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| 1 | A New Method of Estimating United States and State‐level Cancer Incidence Counts for the Current Calendar Year显示文摘 | Linda W.Pickle YongpingHao AhmedinJemal ZhaohuiZou Ram C.Tiwari ElizabethWard MarkHachey Holly L.Howe Eric J.Feuer | 2009 | CA: A Cancer Journal for Clinicians2009，，1： | 2 |
| 2 | Annual report to the nation on the status of cancer, 1975–2001, with a special feature regarding survival显示文摘 | AhmedinJemal Limin X.Clegg ElizabethWard Lynn A. G.Ries XiaochengWu Patricia M.Jamison Phyllis A.Wingo Holly L.Howe Robert N.Anderson Brenda K.Edwards | 2004 | Cancer2004，，1： | 1 |
| 3 | Annual report to the nation on the status of cancer, 1975–2001, with a special feature regarding survival显示文摘 | AhmedinJemal Limin X.Clegg ElizabethWard Lynn A. G.Ries XiaochengWu Patricia M.Jamison Phyllis A.Wingo Holly L.Howe Robert N.Anderson Brenda K.Edwards | 2004 | Cancer2004，，1： | 1 |
| 4 | Systemic evidence of acute seizureassociated elevation in serum neuronal injury biomarker in patients with temporal lobe epilepsy显示文摘Background:Patients with drug refractory temporal lobe epilepsy frequently accumulate cognitive impairment over time,suggesting loss of neurons induced by seizures.Our objective was to determine whether there is a temporal association between changes in serum levels of neural injury markers and electroencephalographic(EEG)evidence of seizures and interictal spikes.Methods:We measured serum levels of neuron-specific enolase(NSE),a neuronal injury marker,relative to levels of S100β,a marker of glial injury,at 6 AM,9 AM,noon,3 PM,and 6 PM over the course of several days in 7 epilepsy patients undergoing continuous video-EEG monitoring and in 4 healthy controls.Results:All epilepsy patients exhibited significant deviations in NSE levels through time,and 4 of the epilepsy patients exhibited large sample entropy values and large signal variation metrics for NSE relative to S100β.Controls did not exhibit such changes.Correlation analysis revealed that NSE levels were significantly elevated after seizures.There was also a highly significant relationship between increased EEG spike frequency and an increase in serum NSE levels measured 24 h later.Conclusions:The detection of large but transient post-ictal increases in NSE suggests that even self-limited seizures may cause an injury to neurons that underlies cognitive decline in some patients.While this study used a small patient population,the pilot findings suggest that post-ictal assessment of serum NSE may serve as a biomarker for measuring the efficacy of future acute neuroprotective strategies in epilepsy patients. | Shailaja Kunda Reghann G.LaFrance-Corey Fatemeh Khadjevand Gregory A.Worrell Charles L.Howe | 2019 | Acta Epileptologica2019，1，1： | 1 |
| 5 | Trends in Breast Cancer by Race and Ethnicity: Update 2006显示文摘 | CarolSmigal AhmedinJemal ElizabethWard VilmaCokkinides RobertSmith Holly L.Howe MichaelThun | 2009 | CA: A Cancer Journal for Clinicians2009，，3： | 1 |
| 6 | Insula and the Immune System:More than mere Co-existence?显示文摘Does the Brain Regulate the Immune System?While long considered to be separate entities,increasing evidence has demonstrated that thebrain and theperipheral immune system interact through bidirectional feedback[1].The brain hosts a vibrant immune environment(e.g.microglia and perivascular macrophages)that is responsible for maintaining the integrity of the central nervous system[2].In addition,the brain is the central regulator of the rest of the body and its homeostasis. | Panagiotis Kerezoudis Charles L.Howe Long-Jun Wu Brian N.Lundstrom Jamie J.Van Gompel | 2022 | Neuroscience Bulletin2022，38，10： | 0 |
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