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| 1 | Aspirin-induced small bowel injuries and the preventive effect of rebamipide显示文摘AIM:To evaluate the influence of taking low-dose aspirin for 4 wk on small intestinal complications and to examine the preventive effect of rebamipide.METHODS:This study was conducted as a single-center,randomized,double-blind,cross-over,placebo-controlled study.Eleven healthy male subjects were enrolled.Each subject underwent video capsule endos-copy after 1 and 4 wk of taking aspirin and omepra-zole,along with either rebamipide or placebo therapy.The primary endpoint was to evaluate small bowel damage in healthy subjects before and after taking low-dose aspirin for 4 wk.RESULTS:The number of subjects with mucosal breaks(defined as multiple erosions and/or ulcers)were 1 at 1 wk and 1 at 4 wk on the jejunum,and 6 at 1 wk(P = 0.0061)and 7 at 4 wk on the ileum(P =0.0019).Rebamipide significantly prevented mucosal breaks on the ileum compared with the placebo group(P = 0.0173 at 1 wk and P = 0.0266 at 4 wk).CONCLUSION:Longer-term,low-dose aspirin adminis-tration induced damage in the small bowel.Rebamipide prevented this damage,and may be a candidate drug for treating aspirin-induced small bowel complications. | Kazuhiro Mizukami Kazunari Murakami Takashi Abe Kunimitsu Inoue Masahiro Uchida Tadayoshi Okimoto Masaaki Kodama Toshio Fujioka | 2011 | World Journal of Gastroenterology2011，17，46： | 8 |
| 2 | WAVE TRANSMISSION AND REFIECTION DUE TO A THIN VERTICAL BARRIER显示文摘WT5”BZ]A numerical method, the boundary fitted coordinate method (BFC), was used to investigate the transmission and reflection of water waves due to a rigid thin vertical barrier descending from the water surface to a depth, i.e., a curtain-wall type breakwater. A comparison between the present computed results and previous experimental and analytical results was carried out which verifies the prediction of the BFC method. Wave transmission and reflection due to the barrier were computed, and the transmission and refiection coefficients were given in a figure. [WT5”HZ] | Gao Xue-ping Hydraulics Institute, School of Civil Engineering, Tianjin University, Tianjin300072, China Nakamura Takayuki , Inouchi Kunimitsu Ehime University, Matsuyama 790-8577, Japan Kakinuma Tadao Nagasaki Comprehensive University, Nagasaki | 2001 | Journal of Hydrodynamics2001，13，1： | 4 |
| 3 | Monomorphic epitheliotropic intestinal T-cell lymphoma presenting as melena with long-term survival: A case report and review of literature显示文摘BACKGROUND Monomorphic epitheliotropic intestinal T-cell lymphoma(MEITL)is a rare primary intestinal T-cell lymphoma,previously known as enteropathy-associated T-cell lymphoma type II.MEITL is an aggressive T-cell lymphoma with a poor prognosis and high mortality rate.The known major complications of MEITL are intestinal perforation and obstruction.Here,we present a case of MEITL that was diagnosed following upper gastrointestinal bleeding from an ulcerative duodenal lesion,with recurrence-free survival for 5 years.CASE SUMMARY A 68-year-old female was admitted to our hospital with melena and mild anemia.An urgent esophagogastroduodenoscopy(EGD)revealed bleeding from an ulcerative lesion in the transverse part of the duodenum,for which hemostatic treatment was performed.MEITL was diagnosed following repeated biopsies of the lesion,and cyclophosphamide,doxorubicin,vincristine,and prednisone(CHOP)chemotherapy was administered.She achieved complete remission after eight full cycles of CHOP therapy.At the last follow-up examination,EGD revealed a scarred ulcer and 18Fluorodeoxyglucose(18FDG)positron emission tomography/computed tomography showed no abnormal FDG accumulation.The patient has been in complete remission for 68 mo after initial diagnosis.CONCLUSION To rule out MEITL,it is important to carefully perform histological examination when bleeding from a duodenal ulcer is observed. | Sotaro Ozaka Kunimitsu Inoue Tomoya Okajima Takako Tasaki Shimpei Ariki Hideki Ono Takeaki Ando Tsutomu Daa Kazunari Murakami | 2021 | World Journal of Gastroenterology2021，27，38： | 3 |
| 4 | The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels显示文摘 | Yoshihisa Ozoe Miho Asahi Fumiyo Ozoe Kunimitsu Nakahira Takeshi Mita | 2009 | Biochemical and Biophysical Research Communications2009，，1： | 1 |
| 5 | Chemistry and toxicology of cyclic heptapeptide toxins, the microcystins from cyanobacteria 显示文摘 | Kunimitsu K | 1994 | Microbiol Cult Coll1994，，10： | 1 |
| 6 | Camphor ionic liquid: correlation between stereoselectivity and cation-anion interaction 显示文摘 | NOBUOKA K KITAOK A S KUNIMITSU K | 2005 | J Org Chem2005，70，24： | 1 |
| 7 | Total microcystin determination using erythro-2-methyl-3-(methoxy-d3)-4-phenylbutyric acid (MMPBd3) as the internal standard显示文摘 | Tomoharu Sano | 1999 | Analytica Chimica Acta1999，386，： | 1 |
| 8 | Microcystin composition of an axenic clonal strain of Microcystis viridis and Microcystis viridis-containing waterblooms in Japanese freshwaters显示文摘 | Kunimitsu Kaya Makoto M. Watanabe | 1990 | Journal of Applied Phycology1990，，2： | 1 |
| 9 | Squalene Quantification Using Octadecylbenzene as the Internal Standard显示文摘 | Hiroshi Matsuura Makoto M. Watanabe Kunimitsu Kaya | 2012 | Procedia Environmental Sciences2012，，： | 1 |
| 10 | Microcystin composition of an axenic clonal strain of Microcystis viridis and Microcystis viridis-containing waterblooms in Japanese freshwaters显示文摘 | Kunimitsu Kaya Makoto M. Watanabe | 1990 | Journal of Applied Phycology1990，，2： | 1 |
| 11 | Precipitation behavior of Laves phase and its effect on toughness of 9Cr-2Mo Ferritic-martensitic steel 显示文摘 | HOSOI Y WADEN KUNIMITSU S | 1986 | Journal of Nuclear Materials1986，，： | 1 |
| 12 | Echinenone production of a dark red-coloured strain of Botryococcus braunii 显示文摘 | Hiroshi M Makoto M W Kunimitsu K | 2012 | Journal of Applied Phycology2012，24，4： | 1 |
| 13 | Public health response to the combined Great East Japan Earthquake, tsumani and nuclear power plant accident: perspective from the ministry of health, labour and welfare of Japan 显示文摘 | Saito T Kunimitsu A | 2011 | Western Pacific Surveillance and Response Journal2011，2，4： | 1 |
| 14 | Non- small cell lung carcinoma therapy using mTOR-siRNA显示文摘 | Matsubara H Sakakibara K Kunimitsu T | 2012 | Int J Clin Exp Pathol2012，5，2： | 1 |
| 15 | Graceful exit from Higgs G-inflation显示文摘 | KAMABA K KOBAYASHI T KUNIMITSU T | 2013 | Phys Rev D2013，88，12： | 1 |
| 16 | Precipitation Behavior of Laves Phase and its Ef{ect on Toughness of 9Cr-2Mo Ferrit- ic-Martensitic Steel 显示文摘 | Hosoi Y Wade N Kunimitsu S | 1986 | Journal of Nuclear Materials1986，，141143： | 1 |
| 17 | Selective control of Microcystis using an amino acid – a laboratory assay显示文摘 | Annett Hehmann Kunimitsu Kaya Makoto M. Watanabe | 2002 | Journal of Applied Phycology2002，，2： | 1 |
| 18 | Nonsmall cell lung carcinoma therapy using mTOR-siRNA 显示文摘 | Matsubara H Sakakibara K Kunimitsu T | 2012 | Int J Clin Exp Pathol2012，5，2： | 1 |
| 19 | Total microcystin determination using erythro-2-methyl-3-(methoxy-d3)-4-phenylbutyric acid (MMPB-d3) as the internal standard显示文摘 | Kunimitsu Kaya Tomoharu Sano | 1999 | Analytica Chimica Acta1999，386，12： | 1 |
| 20 | Crystal growth and structure refinement of monoclinic Li2TiO3显示文摘 | KUNIMITSU K YASUHIKO T | 2009 | Materials Research Bulletin2009，44，5： | 1 |
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