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| 1 | Fluctuations in butyrate-producing bacteria in ulcerative colitis patients of North India显示文摘AIM: To study the interplay between butyrate concentration and butyrate-producing bacteria in fecal samples of ulcerative colitis (UC) patients vs control individuals. METHODS: Fecal samples were collected from 14 control individuals (hemorrhoid patients only) and 26 UC patients (severe: n = 12, moderate: n = 6, remission: n = 8), recruited by the gastroenterologist at the Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India. Disease activity in UC patients was determined by clinical colitis activity index. We employed fluorescent in situ hybridization in combination with flow cytometry to enumerate the clostridium cluster population targeted by 16S rRNA gene probe. Major butyrate-producing species within this cluster were quantified to see if any change existed in control vs UC patients with different disease activity. This observed change was further validated by quantitative polymerase chain reaction. In addition to this,we carried out gas chromatography to evaluate the changes in concentration of major short chain fatty acids (SCFAs), namely acetate, n -butyrate, iso -butyrate, in the above samples. Student t test and Graph pad prism-6 were used to compare the data statistically. RESULTS: There was a significant decrease of Clostridium coccoides (control, 25.69% ± 1.62% vs severe, 9.8% ± 2.4%, P = 0.0001) and Clostridium leptum clusters (control, 13.74% ± 1.05% vs severe, 6.2% ± 1.8%, P = 0.0001) in fecal samples of UC patients. Furthermore, we demonstrated that some butyrateproducing members of the clostridial cluster, like Fecalibacterium prausnitzii (control, 11.66% ± 1.55% vs severe, 6.01% ± 1.6%, P = 0.0001) and Roseburia intestinalis (control, 14.48% ± 1.52% vs severe, 9% ± 1.83%, P = 0.02) were differentially present in patients with different disease activity. In addition, we also demonstrated decreased concentrations of fecal SCFAs, especially of n -butyrate (control, 24.32 ± 1.86 mmol/μL vs severe, 12.74 ± 2.75 mmol/μL, P = 0.003), iso -butyrate (control, 1.70 ± 0.41 mmol/μL vs severe, 0.68 ± 0.24 mmol/μL, P = 0.0441) and acetate (control, 39.51 ± 1.76 mmol/μL vs severe, 32.12 ± 2.95 mmol/ μL,P = 0.047), in the fecal samples of UC patients. The observed decrease of predominant butyrate producers of clostridial clusters correlated with the reduced SCFA levels in active UC patients. This was further confirmed by the restoration in the population of some butyrate producers with simultaneous increase in the level of SCFA in remission samples. CONCLUSION: Our observations indicate that decreases in members of the clostridial cluster resulting in reduced butyrate levels contribute to the etiology of UC. | Reena Kumari Vineet Ahuja Jaishree Paul | 2013 | World Journal of Gastroenterology2013，19，22： | 21 |
| 2 | Endocytosis unplugged: multiple ways to enter the cell显示文摘Endocytosis 在房间表面发生并且与它的成分膜蛋白质和类脂化合物一起包含血浆膜(下午) 的成为主观。Endocytosis 涉及细胞外的周围的采样并且也服务调整在房间表面开始的各种各样的过程。这些包括滋养的举起,从房间表面受体,和为在 metazoans 工作的房间和织物的许多另外的过程必需品发信号。它对下午类脂化合物和蛋白质动态平衡的维护也中央。有成为主观的多重工具并发地操作,在房间表面。与在高分辨率的可视化技术的前进,同时追踪多重 endocytic 货物现在是可能的,揭示在一个单个房间的 endocytic 进程的显著差异。实时房间成像和有效基因操作的联合也帮助了在成为主观的这些机制理解分子的播放器的功能的层次。这里,我们提供各种各样的 endocytic 线路的一篇报道,他们越过数的操作和出现的机制。 | Sudha Kumari Swetha MG Satyajit Mayor | 2010 | Cell Research2010，20，3： | 19 |
| 3 | 乳腺癌患者延续护理研究现状显示文摘论述乳腺癌患者延续护理需求、干预模式和提出建议。护理需求包括后续治疗、伤口护理、功能锻炼、日常自理等;干预模式包括基于医院的延续护理(随访,成立乳腺癌患者俱乐部,制定出院计划等)、基于社区的延续护理(日间医院,家庭医院/访视)及医院-社区-家庭三位一体的延续护理。建议加强延续护理相关培训,发展专业护理人员及健全相关法规制度,以促进乳腺癌患者延续护理体系的健全与发展。 | 吴珂 贾会英 妮娜 周梦 Nira Kumari Shahi 彭歆 | 2017 | 护理学杂志2017，32，20： | 18 |
| 4 | 社区护理人员灾害准备的研究进展显示文摘对国内外社区护理人员灾害准备模式、存在的问题、影响因素、培训现状及测量工具进行综述。提出应建立完善的社区护理人员灾害准备培训体系,建立适合我国国情的社区护理人员灾害应对准备模式并建立社区护理人员灾害准备测量工具的区域性常模,旨在为今后提高社区护理人员的灾害准备度提供参考依据。 | 周梦 妮娜 贾会英 吴珂 Nira Kumari Shahi 彭歆 | 2018 | 护理学杂志2018，33，2： | 12 |
| 5 | Association between obesity-related adipokines and colorectal cancer:A case-control study and meta-analysis显示文摘AIM:To examine the association between obesityrelated adipokines(adiponectin,leptin,resistin,interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)and colorectal cancer(CRC)risk.METHODS:Serum levels of adipokines were measured in 100 CRC patients and age-and sex-matched controls for the data analysis.Unconditional logistic regression models were used for estimating ORs and95%CIs related to each adipokine.For the metaanalysis,studies published before July 2013 available on Medline/PubMed and EMBASE were retrieved.The analysis included a total of 17 relevant studies(including the present case-control study):nine studies on adiponectin and eight on leptin.The effect sizes of ORs and 95%CIs were estimated using RevMan 5.1.Heterogeneity was evaluated using Cochran’s Q-test and I2 statistics.RESULTS:Among the five adipokines,only resistin levels were significantly higher in cases than in controls(P<0.001).The case-control study results showed no association between adiponectin and CRC and a negative association between leptin and CRC.However,the results of the meta-analysis showed a significant inverse association between adiponectin and CRC(OR=0.91,95%CI:0.83-1.00,P=0.04)and no association between CRC and leptin.After stratification by study design,an inverse association between adiponectin and CRC was observed in prospective studies only(OR=0.90,95%CI:0.82-0.99,P=0.03),whereas the association between leptin and CRC was inconsistent(prospective studies:OR=1.14,95%CI:1.02-1.27,P=0.02 and retrospective studies:OR=0.47,95%CI:0.29-0.74,P=0.001).The associations of resistin and TNF-αwith CRC risk were positive,but no association was observed for IL-6.CONCLUSION:Our results suggest a negative association of leptin,positive associations of resistin and TNF-α,and null associations of adiponectin and IL-6with CRC.However,further studies with larger number of prospective approaches are needed. | Rakhi Kumari Joshi Woo Jin Kim Sang-Ah Lee | 2014 | World Journal of Gastroenterology2014，20，24： | 11 |
| 6 | Marine Bacterial Biofilms in Bioremediation of Polycyclic Aromatic Hydrocarbons(PAHs) Under Terrestrial Condition in a Soil Microcosm显示文摘Polycyclic aromatic hydrocarbons(PAHs) in soil retain for a quite long period due to their hydrophobicity and aggregation properties. Biofilm-forming marine bacterial consortium(named as NCPR), composed of Stenotrophomonas acidaminiphila NCW702,Alcaligenes faecalis NCW402, Pseudomonas mendocina NR802, Pseudomonas aeruginosa N6P6, and Pseudomonas pseudoalcaligenes NP103, was used for the bioremediation of PAHs in a soil microcosm. Phenanthrene and pyrene were used as reference PAHs. Parameters that can affect PAH degradation, such as chemotaxis, solubility of PAHs in extracellular polymeric substances(EPS), and catechol2,3-dioxygenase(C23O) activity, were evaluated. P. aeruginosa N6P6 and P. pseudoalcaligenes NP103 showed chemotactic movement towards both the reference PAHs. The solubility of both the PAHs was increased with an increase in EPS concentration(extracted from all the 5 selected isolates). Significantly(P < 0.001) high phenanthrene(70.29%) and pyrene(55.54%) degradation was observed in the bioaugmented soil microcosm. The C23O enzyme activity was significantly(P < 0.05) higher in the bioaugmented soil microcosm with phenanthrene added at 173.26 ± 2.06 nmol min^(-1) mg^(-1) protein than with pyrene added at 61.80 ± 2.20 nmol min^(-1) mg^(-1) protein. The C23O activity and gas chromatography-mass spectrometer analyses indicated catechol pathway of phenanthrene metabolism. However, the metabolites obtained from the soil microcosm added with pyrene revealed both the catechol and phthalate pathways for pyrene degradation. | Neelam MANGWANI Supriya KUMARI Surajit DAS | 2017 | Pedosphere2017，27，3： | 10 |
| 7 | 多学科乳腺癌团队在乳腺癌患者决策辅助中的应用研究进展显示文摘乳腺癌是全世界女性最常见的恶性肿瘤之一,随着乳腺癌诊断、分期及管理的演变和完善,其治疗方案变得越来越复杂.由于存在多种有效治疗方案,有学者认为在遵循法律和道德的原则下,尊重患者的自主权至关重要,因此,有必要让乳腺癌患者参与到治疗决策中. | 韦文棋 吴珂 贾会英 周梦 妮娜 王粲霏 Nira Kumari Shahi 彭歆 | 2018 | 解放军护理杂志2018，35，19： | 10 |
| 8 | Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study显示文摘A simple and rapid liquid chromatography-tandem mass spectrometric(LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human plasma.Irbesartan was used as an internal standard.The analytes were extracted from human plasma samples by solid-phase extraction technique using a Strata-X 33 mm polymeric sorbent.The reconstituted samples were chromatographed on a C18 column by using a 80:20(v/v) mixture of acetonitrile and 0.1% formic acid as the mobile phase at a flow rate of 0.8 mL/min.The calibration curves obtained were linear(rZ0.99) over the concentration range of 15-3000 ng/mL for pioglitazone and 5-608 ng/mL for candesartan.The results of the intra-and inter-day precision and accuracy studies were well within the acceptable limits.A run time of 2.7 min for each sample made it possible to analyze more than 300 plasma samples per day.The proposed method was found to be applicable to clinical studies. | Vijaya Kumari Karra Nageswara Rao Pilli Jaswanth Kumar Inamadugu J.V.L.N.Seshagiri Rao | 2012 | Journal of Pharmaceutical Analysis2012，2，3： | 8 |
| 9 | 一类具有非线性发生率的无线传感网络蠕虫传播模型的延迟动力学行为(英文)显示文摘研究了一类具有不同发生率的无线传感网络蠕虫传播模型的延迟动力学行为。由于在监测节点隔离不稳定节点需要消耗一定的时间,在模型中考虑了处理时滞。通过分析相应特征方程根的分布情况,得到了平衡点存在性、模型局部稳定性和Hopf分岔存在的充分性条件。通过构造合适的李雅普诺夫函数,证明了蠕虫病毒平衡点的全局稳定性。数值仿真实验验证了理论分析结果的正确性。仿真结果表明,当处理时滞的值越过关键值时,网络中的蠕虫传播将失去控制,发现无线传感网络的覆盖范围是控制蠕虫传播和保证无线传感网络安全最为重要的因素之一。并通过仿真发现消除模型混沌状态的一些关键参数,其中非线性发生率βSI/I+1是控制蠕虫病毒传播、保证无线传感网络安全的最佳选择。 | 张子振 储煜桂 KUMARI Sangeeta UPADHYAY Ranjit Kumar | 2019 | 浙江大学学报(理学版)2019，46，2： | 6 |
| 10 | Hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatocellular damage in Wistar albino rats显示文摘Objective:To evaluate the hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatic damage in rats.Methods:The plant material was shade dried, powdered and extracted with ethanol.Liv 52 and silymarin were used as standard drugs and 2%gum acacia as a control(vehicle).Alteration in the levels of biochemical markers of hepatic damage like AST,ALT,ALP and lipid peroxides were tested,and phytochemical tests were also performed.Results:Paracetamol(2 g/kg) increased the serum levels of alanine aminotransfer (ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP) and the lipid peroxides. Treatment of Liv 52,silymarin and ethanolic extract of Terminalia paniculata(200 mg/kg) altered levels of biochemical marker and showed significant hepatoprotective activity.Ethanolic extract revealed the presence of phenolic compound and flavanoids.Our findings suggested that ethanolic bark extract of Terminalia paniculata possessed hepatoprotective activity in a dose dependent manner.Conclusions:Terminalia paniculata possesses hepatoprotective activity.It could be an effective and promising preventive agent against PCT induced hepatotoxicity. | Eesha BR Mohanbabu Amberkar V Meena Kumari K Sarath babu Vijay M Lalit M Rajput R | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 5 |
| 11 | Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease显示文摘AIM: To study the effect of regular aerobic exercise on insulin resistance, serum aminotransferase and liver histology in nonalcoholic fatty liver disease (NAFLD) patients. METHODS: Sixty (mean age 40.0 ± 8.5 years, 75% male) NAFLD patients were included in the study. After baseline anthropometric measurement i.e., body mass index (BMI), waist circumference (WC); all patients were advised regular aerobic exercise for 30 min/d, for at least 5 d/wk and trained to achieve around 70% of his maximal heart rate. In addition, moderately energy restricted diet was advised to patients with high BMI (> 25 kg/m 2 ). Monthly follow up was done by measuring BMI, WC, aspartate aminotransferase, and alanine aminotransferase (ALT). Insulin resistance was calculated using homeostasis model assessment (HOMA) of insulin resistance (HOMA-IR) model, at baseline and after 6mo. Insulin resistance was arbitrarily considered altered when it was ≥ 2. Liver biopsy was done in a section of patients at baseline and after 6 mo. RESULTS: Seventy percent (42/60) patients were overweight or obese; 95% (57/60) had central obesity (WC > 90 cm in men, > 80 cm in women). In the 45 exercise compliant patients insulin resistance decreased from 6.4 ± 6.1 to 1.3 ± 1.0, BMI from 26.7 ± 3.3 kg/m 2 to 25.0 ± 3.3 kg/m 2 , WC from 95.7 ± 8.9 cm to 90.8 ± 7.3 cm and ALT from 84.8 ± 43.5 U/L to 41.3 ± 18.2 U/L (P < 0.01). In 15 exercise noncompliant patient's insulin resistance, BMI, WC and ALT did not show significant change at 6 mo follow up. Six of 8 patients in compliant group on repeat liver biopsy showed significant change in steatosis and necroinflammation. Nonalcoholic steatohepatitis scores improved form 5.3 ± 1.5 to 3.35 ± 1.5. The decline in insulin resistance correlated with decline in ALT (P = 0.01, r s = 0.90) and liver histology (P = 0.03, r s = 0.73). CONCLUSION: Life style modification improves insulin resistance resulting in improvement in ALT and liver histology in NAFLD patients. | Ganesh Bhat Chalamalasetty Sreenivasa Baba Amaresh Pandey Neeraj Kumari Gourdas Choudhuri | 2012 | World Journal of Hepatology2012，4，7： | 5 |
| 12 | Palladium-Catalyzed Asymmetric [4+3]-Cyclization Reaction of Fused 1-Azadienes with Amino-trimethylenemethanes: Highly Stereoselective Construction of Chiral Fused Azepines显示文摘Summary of main observation and conclusion A Pd-catalyzed asymmetric aromative[4+3]-cyclization reaction of amino-trimethylenemethanes(TMM,1d,ip3-oles)with fused 1-azadienes has been developed.This method enables access to the synthetically importance and biologically active benzofuran fused azepines and indeno-azepines in excellent efficiency and stereoselectivity(up to 95%yield,99%ee,>19:1 dr). | Prathibha Kumari Weiwei Liu Cheng-Jie Wang Jun Dai Mei-Xin Wang Qi-Qiong Yang Yu-Hua Deng Zhihui Shao | 2020 | Chinese Journal of Chemistry2020，38，2： | 5 |
| 13 | Donors for Resistance to Brown Planthopper Nilaparvata lugens(St?l) from Wild Rice Species显示文摘Out of 1 989 wild accessions sown in seed boxes for screening, only 1 003 wild accessions with good germination were screened against brown planthopper(BPH), Nilaparvata lugens(St?l) under greenhouse conditions. The collection comprised of accessions from 11 wild species and African cultivated rice. The germplasm was screened for BPH following standard seed box screening technique in the greenhouse. As many as 159 accessions were identified as resistant during the year 2012 based on one year screening. A selected set of BPH resistant accessions were screened again during 2013. Based on the two years screening, seven accessions of O. nivara(AA), one accession of O. officinalis(CC), seven accessions of O. australiensis(EE), five accessions of O. punctata(BB and BBCC) and nine accessions of O. latifolia(CCDD) were confirmed to be resistant to BPH. So far no BPH resistance genes have been identified and designated from O. nivara and O. punctata, hence these may act as new sources of resistance. | Preetinder S. SARAO Gurpreet K. SAHI Kumari NEELAM Gurjit S. MANGAT Bhaskar C. PATRA Kuldeep SINGH | 2016 | Rice science2016，23，4： | 5 |
| 14 | Effect of nitrogen doping on structural and optical properties of ZnO nanoparticles显示文摘Infl uence of nitrogen doping on structural and optical properties of ZnO nanoparticles has been studied. Undoped and N doped ZnO nanoparticles were synthesized via chemical precipitation approach. The prepared samples were characterized through X-ray diffraction(XRD),Transmission electron microscopy(TEM) equipped with Energy dispersive X-ray(EDAX) spectroscopy, UV–visible spectroscopy, Fourier transform infrared(FTIR) spectroscopy and micro-Raman spectroscopy(m RS). Wurtzite phase of undoped as well as 0.5–10% N doped ZnO nanoparticles was con fi rmed through characteristic XRD patterns. The particle size expansion due to N incorporation in ZnO was further revealed by TEM and EDAX analysis where 11 nm size undoped and 18–22 nm size 0.5–10% N doped ZnO(N:ZnO) nanoparticles without any impurity were ascertained. Slight blue-shift in band gap energy, as observed in our case, symbolized weak quantum con fi nement of the prepared nanoparticles. The alterations in vibrational modes of ZnO due to N incorporation, remarkably H substituting at O site and subsequently causing the passivation in N:ZnO nanoparticles, were detected through FTIR analysis. Finally, the effect of the nano-size of crystallite and gradual prominence of N into ZnO lattice due to increase of N doping concentration in prepared nanoparticles was meticulously expatiated though m RS analysis. | Renu Kumari Anshuman Sahai Navendu Goswami | 2015 | Progress in Natural Science:Materials International2015，25，4： | 4 |
| 15 | A systematic review on the aboveground biomass and carbon stocks of Indian forest ecosystems显示文摘Background:Tropical forests play a crucial role as source and sink in global carbon cycle.Development and other anthropogenic activities have led to degradation of forest land,and ultimately,it results in loss of biodiversity and increases concentration of CO_(2) in atmospheres.Therefore,there is urgent need to estimate regional and national level carbon stock for making forest-based policies and strategies for mitigation of CO_(2).Patchy and sporadic information is available on biomass and carbon stock of Indian forests.The paper presents a systematic review and comprehensive account of studies conducted in different forest types in India.Result:There are six major forest types found in India consisting of 15 groups and other subgroups with peculiar characteristics.Methodologies used by researchers for biomass/carbon stock estimation are destructive,nondestructive,tree inventories data,species-specific biomass estimation,and remote sensing.Majority of estimates are based on nondestructive allometric equation approach.Studies showed positive correlation between tree species,diameter at breast height,and biomass/carbon stock.Small-and medium-sized growing trees,invasive species,mixed forest,Agroforestry,and Agrosilviculture also play an important role in atmospheric carbon assimilation.The results of diverse forest carbon stock studies are broadly categorized in North,Central,and Southern India.Present review will be helpful for developing conservation policies and decision to increase carbon stock and also REDD+program for particular forest ecosystem.Conclusion:The systematic literature review was carried out to gather and summarize information from different studies conducted on forest ecosystems and quantification methods used for biomass estimation and carbon stock in different forests types and states of India.In general,great variability occurs in aboveground biomass and carbon stock on account of climatic and geographic differences.To obtain good and accurate estimations,following nondestructive approach,species-specific density-based equations are required from different habitats and also in relation to degradation status of forests.As such regional volume equations would increase error of estimations.The comprehensive account of data would be helpful to formulate strategies based on carbon sequestration in Indian forests for CO_(2) mitigation. | Onkar Salunkhe P.K.Khare Richa Kumari M.L.Khan | 2018 | Ecological Processes2018，7，1： | 4 |
| 16 | Screening of Antioxidant Potential of Selected Barks of Indian Medicinal Plants by Multiple in vitro Assays显示文摘Objective To evaluate the antioxidant potential in herbal extract barks of five therapeutically important medicinal plants native to India, i.e. Crataeva nurvala Buch.-Ham., Buchanania lanzan Spreng., Aegle marmelos Corr., Dalbergia sissoo Roxb. ex DC., and Cedrela toona Roxb. Methods Standardized aqueous alcoholic extracts from the selected barks having different target radicals, such as superoxide radical, nitric oxide, ABTS radical, and peroxidative decomposition of phospholipids, were prepared and screened by multiple in vitro assays. These extracts were also tested for total phenolic and tannin content and correlated with antioxidant capacity. Results Total phenolic and tannin contents were found to be the highest in C. nurvala (195 GAE mg/g and 218.3 mg/g CE). SOD mimetic activity was found to be the highest in Crataeva nurvula, although all barks showed activity more than 100 units/mg extract. Lipid peroxidation inhibitory potential was found to be the highest in Crataeva nurvala (83.4% inhibition of MDA formation/10 μg extract), and also showed a comparatively high NO quenching capacity (45.5% per 10 μg extract). The highest NO quenching potential was found in Aegle marmelos (47.3% per 10 μg extract). Cedrela toona showed the lowest LPO inhibitory potential and NO quenching capacity (50.5% and 30.5%, respectively). Buchanania lanzan, a medicinal plant extensively used for inflammatory disorders and Dalbergia sissoo also showed 72.5% and 69.1% LPO inhibitory potential/10 μg extract. Trolox equivalent antioxidant capacity ranged from 0.24 to 0.39 mmol/L TEAC/mg extract, indicating that all the barks tested had ABTS+· radical quenching capacity. Conclusion Bark of Crataeva nurvula has the highest antioxidant capacity and a positive correlation between antioxidant activity and their plendic content was found. | ARCHANA KUMARI POONAM KAKKAR | 2008 | Biomedical and Environmental Sciences2008，21，1： | 4 |
| 17 | Bismuth Modified Porous Silica Preparation,Characterization and Photocatalytic Activity Evaluation for Degradation of Isoproturon显示文摘Porous silica prepared by using an acrylic emulsion has been impregnated with bismuth ion resulting in Bi_2SiO_5 species containing surface.The as-prepared materials have been characterized by X-ray diffraction spectroscopy (XRD),X-ray photoelectron spectroscopy(XPS),UV-Vis diffuse reflectance spectroscopy(UV-Vis DRS), scanning electron microscopy(SEM),energy dispersive analysis of X-ray(EDAX),transmission electron microscopy(TEM),Fourier transform infrared spectroscopy(FTIR) and N_2 adsorption/desorption techniques. EDAX analysis confirms the penetration of bismuth ions into the framework of silica to form Bi_2SiO_5,which is substantiated by XRD.The UV—Vis DRS shows that the catalysts are optically active and XPS confirms the inclusion of bismuth into the framework of silica.FTIR spectra illustrate the formation of Bi—O—Si linkages in the porous silica framework.SEM and TEM show the spherical morphology,whereas N_2 adsorption/desorption study confirms the porosity of the prepared materials.The photocatalytic activity of the material is evaluated for the degradation of isoproturon herbicide and it is found that the material is active as compared to the commercial P-25 Degussa TiO_2. | Anil Kumar Reddy Police Srinivas Basavaraju Durga Kumari Valluri Subrahmanyam Machiraju | 2013 | Journal of Materials Science & Technology2013，29，7： | 4 |
| 18 | Synthesis,spectroscopic characterization,DNA cleavage and antibacterial studies of a novel tridentate Schiff base and some lanthanide(III) complexes显示文摘A novel potential tridentate Schiff base was prepared by condensing equimolar quantities of 2-hydroxyacetophenone and 2-aminopyrimidine in methanol.This ligand was versatile in forming a series of complexes with lanthanide ions such as La(III),Pr(III),Nd(III),Sm(III),Gd(III),Dy(III) and Yb(III).The ligand and the metal complexes were characterized through elemental analysis,molar conductance,UV-Visible,IR,1H NMR,and mass spectral studies.The spectral studies indicated that the ligand was coordinated to the metal ion in neutral tridentate fashion through the azomethine nitrogen,one of the nitrogen atoms in the pyrimidine ring and the phenolic oxygen without deprotonation.Thermal decomposition and luminescence property of lanthanum(III) complex were also examined.The X-ray diffraction patterns showed the crystalline nature of the ligand and its lanthanum(III) complex.The DNA cleavage studies of the ligand and the metal complexes were carried out and it was observed that the lanthanum(III) and neodymium(III) complexes cleaved the pUC19 DNA effectively.The ligand and the metal complexes were screened for their antibacterial activities.The metal complexes were found to be more potent bactericides than the ligand. | K.Mohanan R.Aswathy L.P.Nitha Niecy Elsa Mathews B.Sindhu Kumari | 2014 | Journal of Rare Earths2014，32，4： | 4 |
| 19 | Er^(3+)/Yb^(3+)/Li^+/Zn^(2+):Gd_2(MoO_4)_3 upconverting nanophosphors in optical thermometry显示文摘Er^(3+)-Yb^(3+)-Li^+:Gd_2(MoO_4)_3 and Er^(3+)-Yb^(3+)-Zn^(2+):Gd_2(MoO_4)_3 nanophosphors, synthesized by chemical co-precipitation technique were characterized through XRD,FESEM,dynamic light scattering(DLS),diffuse reflectance, photoluminescence, photometric and decay time analysis. The enhancement of about~28, ~149 and ~351 times in the green upconversion emission band is observed for the optimized Er^(3+)-Yb^(3+),Er^(3+)-Yb^(3+)-Li^+ and Er^(3+)-Yb^(3+)-Zn^(2+):Gd_2(MoO_4)_3 nanophosphors in comparison to the singly Er^(3+) doped nanophosphors. The electric dipole-dipole interaction is found to be responsible for the concentration quenching. The temperature dependent behaviour of the two green thermally coupled levels of the Er^(3+) ions based on the fluorescence intensity ratio technique was studied. The maximum sensor sensitivity ~38.7 × 10^(-3) K^(-1) at 473 K for optimized Er^(3+)-Yb^(3+)-Zn^(2+) codoped Gd_2(MoO_4)_3 nanophosphors is reported with maximum population redistribution ability~88% among the ~2H_(11/2) and ~4S_(3/2) levels. | Anita Kumari Lakshmi Mukhopadhyay Vineet Kumar Rai | 2019 | Journal of Rare Earths2019，37，3： | 4 |
| 20 | Effect of Low Level Subchronic Microwave Radiation on Rat Brain显示文摘Objective The present study was designed to investigate the effects of subchronic low level microwave radiation(MWR) on cognitive function,heat shock protein 70(HSP70) level and DNA damage in brain of Fischer rats.Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900,1800,and 2450 MHz.Animals were divided into 4 groups: Group I: Sham exposed,Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate(SAR) 5.953 × 10-4 W/kg,Group III: animals exposed to 1800 MHz at SAR 5.835 × 10-4 W/kg and Group IV: animals exposed to 2450 MHz at SAR 6.672 × 10-4 W/kg.All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues.HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay.Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function,increase in HSP70 level and DNA damage in brain.Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900,1800,and 2450 MHz may lead to hazardous effects on brain. | Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta | 2016 | Biomedical and Environmental Sciences2016，29，12： | 4 |
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