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| 1 | Antioxidant activities of Indigofera cassioides Rottl.Ex.DC.using various in vitro assay models显示文摘Objective:To evaluate the antioxidant potential of methanolic leaf extract of Indigofera cassioides(MEIC) using various in vilro antioxidant assay systems.Methods:Antioxidant and free radical scavenging activity of MEIC was assayed by using different in vitro models like ABTS, DPPH,nitric oxide,superoxide,hydrogen peroxide and hydroxyl radical.Reductive ability of the extract was tested by the complex formation with potassium ferricyanide.Further total phenol and flavonoid contents of the crude extract were also determined.Rutin and ascorbic acid were used as standards.Results:MEIC exhibited potent and concentration dependent free radical scavenging activity in all the tested models.Reductive ability was also found to increase with increase in MEIC concentration.Total phenol and flavonoid content determination showed that the extract is rich in phenols and flavonoids.Conclusions:All the results of the in vitro antioxidant assays reveal potent antioxidant and free radical scavenging activity of the leaves of Indigofera cassioides,equivalent to that of standard ascorbic acid and rutin.This potent antioxidant activity may be attributed to its high phenolic and flavonoid contents. | R Senthil Kumar B Rajkapoor P Perumal | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 15 |
| 2 | Antihyperglycemic and antioxidant effects of Solanum xanthocarpum leaves(field grown & in vitro raised) extracts on alloxan induced diabetic rats显示文摘Objective:To investigate antidiabetic efficacy of the extract of field grown and in vitro raised leaves of Solanum xanthocarpum(S.xanthocarpum) against alloxan induced diabetic rats. Methods:The antidiabetic activity of the crude methanol extracts of the field grown and in vitro raised leaves of S.xanthocarpum at different concentrations(100-200 mg/kg bw) was tested against alloxan induced diabetic rats.The antidiabetic efficacy was validated through various biochemical parameters and the antioxidant effect was also determined.The phytochemical analyses of field grown S.xanthocarpum and in vitro rasied 5.xanthocarpum leaves were done by estimating their chlorophyll,carotenoids,total sugar,protein,amino acid and minerals contents. Results:The results revealed that the methanol extracts of both the leaves(field grown and in vitro raised) of S.xanthocarpum was efficient anti hyperglycemic agents at a concentration of 200 mg/kg bw and posses potent antioxidant activity.However,the extracts of in vitro rasied S.xanthocarpum raised leaves exhibit higher efficacy than the field grown leaves in all tested concentrations.Proximal composition and mineral analysis of S.xanthocarpum revealed higher concentration of contents in in vitro rasied S.xanthocarpum than field grown S.xanthocarpum. Conclusions:From the results it can be concluded that the leaves extracts of S.xanthocarpum can be a potential candidate in treating the hyperglycemic conditions and suits to be an agent to reduce oxidative stress. | K Poongothai P Ponmurugan K Syed Zameer Ahmed B Senthil Kumar SA Sheriff | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，10： | 9 |
| 3 | Phytoextraction:the use of plants to remove heavy metals from soils显示文摘 | NADAN KUMAR P B A DUSHENKOV V MOTTO H | 1995 | Environ Sci Technol1995，29，5： | 2 |
| 4 | Objectively determined 10-day African rainfall estimates created for famine early warning systems显示文摘 | Herman A V B Kumar P A Arkin | 1997 | Int J Remote Sens1997，18，： | 2 |
| 5 | Effect of morin, a flavonoid against DOCA-salt hypertensive rats:a dose dependent study显示文摘Objective:To determine the protective effect of morin, a flavonoid against deoxycorticosterone acetate(DOCA)-salt induced hypertension in male Wistar rats.Methods:Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA(25 mg/kg bw) and 1% NaCl in the drinking water for six consecutive weeks. Effect of morin against DOCA-salt induced hypertension was evaluated by measuring blood pressure and performing biochemical estimations and histopathological examination of renal tissues.Results:DOCA-salt hypertensive rats showed considerably increased systolic and diastolic blood pressure,serum hepatic marker enzyme activities such as aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase(ALP) and gamma-glutamyl transpeptidase(GGT)and renal function markers(urea, uric acid and creatinine) in plasma. Oral administration of morin(25, 50 and 75 mg/kg bw) brought back all the above parameters to near normal level.Histopathology of kidney also confirmed the biochemical findings of this study. The effect at a dose of 50 mg/kg bw of morin was more pronounced than that of the other two doses(25 and 75 mg/kg bw).Conclusions:These findings indicate that morin exhibits strong antihypertensive effect against DOCA-salt induced hypertension. | Prahalathan P Kumar S Raja B | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 2 |
| 6 | Phytoremediation:The use of plants to remove heavy metals from soils 显示文摘 | Nanda - Kumar P B A Dushenkov V Motto H | 1995 | Environmental Science & Technology1995，29，5： | 2 |
| 7 | Antioxidant activity and haemolysis prevention efficiency of polyaniline nanofibers显示文摘 | Somik Banerjee Jyoti P Saikia A Kumar B K Konwar | 2010 | Nanotechnology2010，，4： | 2 |
| 8 | Graft copolymerization of acrylonitrilc onto Cassia tora gum with eerie ammonium nitrate - nitricaeid as a redox initiator显示文摘 | Sharma B R Kumar V Soni P L | 2003 | Journal of Applied Polymer Science2003，，1： | 1 |
| 9 | Influence of source and time of potassium application on potato growth, yield, economics and crisp quality 显示文摘 | Kumar P Pandey S K Singh B P | 2007 | Potato Research2007，50，： | 1 |
| 10 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
| 11 | Phytoremediation:anovel strategy for the removal of toxic metals from the environment using plants显示文摘 | SALT D E BLAYLOCK M KUMAR N P B A | 1995 | Nature Biotechnology1995，13，5： | 1 |
| 12 | Stabilization of γ-sterilized biomedical polyolefins by synergistic mixtures of oligomeric stabilizers 显示文摘 | Alariqi S A Kumar P Rao B | 2006 | Polymer Degradation and Stability2006，91，： | 1 |
| 13 | Endoluminal ultrasonography with reusableprobe: preliminary reusult显示文摘 | KUMAR P V JOSHI H B TIMONEY A G | 2002 | J Endourol2002，16，： | 1 |
| 14 | Selective para-chlorination of toluene using zeolite catalysts显示文摘 | Singh A P Kumar S B Paul A | 1994 | J Catal1994，147，： | 1 |
| 15 | Treatability and flow path studies in bamboo显示文摘 | KUMAR S DOBRIYAL P B | 1992 | Wood and Fiber Science1992，24，2： | 1 |
| 16 | Streptomycin induced protein expression analysis in mycobacterium tuberculosis by two-dimensional gel electrophoresis & mass spectrometry显示文摘 | Sharma P Kumar B Singhal N | 2010 | Indian J Med Res2010，132，： | 1 |
| 17 | Lipopolysaccharides from distinct pathogens induce different classes of immune responses invivo显示文摘 | Pulendran B Kumar P Cutler CW | 2001 | J Immunol2001，167，9： | 1 |
| 18 | Experimental quantifi- cation of chemical effects of hydrodynamic cavitation 显示文摘 | Senthil Kumar P Siva Kumar M Pandit A B | 2000 | Chemical Engineering Science2000，55，9： | 1 |
| 19 | Rigid nasal en- doscopy in the diagnosis and treatment of epistaxis 显示文摘 | Kumar M V V Prasad K U R Gowda P R B | 2013 | J Clin Diagn Res2013，7，5： | 1 |
| 20 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
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