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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Fiber sensor for the simultaneous measurement of current and voltage in a high-voltage system 显示文摘 | Rajkumar N Kumar V J Sankaran P | 1993 | Applied Optics1993，32，7： | 1 |
| 3 | Increased expression of TGF-β1 in brain tissue after ischemic stroke in human显示文摘 | Krupinski J Kuman P Kumar S | 1996 | Stroke1996，27，5： | 1 |
| 4 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
| 5 | Study of occupational stress among railway engine pilots显示文摘 | KUMAR D SINGH J V KHARWAR P S | 2011 | Indian J Occup Environ Med2011，15，1： | 1 |
| 6 | Modeling and control of formations of nonholonomic mobile robots显示文摘 | Desai J P Ostrowski J P Kumar V | 2001 | IEEE Transactions on Robotics and Automation2001，17，6： | 1 |
| 7 | Prevalence and associations of25-hydro-xyvitamin D deficiency in US children:NHANES2001-2004显示文摘 | Kumar J Muntner P Kaskel FJ | 2009 | Pediatrics2009，124，3： | 1 |
| 8 | Ceria added Sb-V2O5/ TiO2 catalysts for low temperature NH3 SCR: Physico-chemical properties and catalytic activity 显示文摘 | Lee K J Kumar P A Maqbool M S | 2013 | Applied Catalysis B : Environ- mental2013，，： | 1 |
| 9 | Intensity Correlation Properties of High-order Optical Vortices Passing Through a Rotation Ground-glass Plate 显示文摘 | Ashok Kumar Banerji J Singh R P | 2010 | Optics Letters(S0146-9592)2010，35，22： | 1 |
| 10 | Novelmethod for isolation of major phenolic constituents from cashew(Anacardium occidentale L) nut shell liquid显示文摘 | Paramashivappa R Kumar P P Vithayathil P J | 2001 | Journal ofAgricultural & Food Chemistry2001，49，25： | 1 |
| 11 | Winter-Time Convection in Open-Graded Embankments显示文摘 | GOERING D J KUMAR P | 1996 | Cold Regions Science andTechnology1996，24，1： | 1 |
| 12 | Corrosion of 2205 duplex stainless steel in chloride medium containing sulfatereducing bacteria 显示文摘 | ANTONY P J CHONGDAR S KUMAR P | 2007 | Eleetrochim Acta2007，52，12： | 1 |
| 13 | Plasticity and reprogramming of differentiated cells in amphibian regeneration显示文摘 | Brockes J P Kumar A | 2002 | Nat Rev Mol Cell Biol2002，，3： | 1 |
| 14 | Pore-sturcture stability and phase transformation in pure and M-doped(M=La,Ce,Nd,Gd,Cu,Fe)alumina membranes and catalyst supports显示文摘 | Kumar K N P Tranto J Kumar J | 1996 | Mater Sci Lett1996，15，： | 1 |
| 15 | miRNA profiling of naive, effector and memory CD8 T cells 显示文摘 | Wu H Neilson J R Kumar P | 2007 | PLoS One2007，2，10： | 1 |
| 16 | Nanoparticles in the Indian environment: known, unknowns and awareness 显示文摘 | KUMAR P KUMAR A LEAD J R | 2012 | Environmental Science & Technology2012，46，： | 1 |
| 17 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 18 | Low temperature wet etching to reveal sub-surface damage in sapphire substrates显示文摘 | KUMAR P LEE J LEE G | 2013 | Applied Surface Science2013，，273： | 1 |
| 19 | LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus显示文摘 | Floyd J L Smith K P Kumar S H | 2010 | Antimicrob Agents Chemother2010，54，12： | 1 |
| 20 | Chromosome doubling in haploids through colchicines 显示文摘 | Gayen P Maden J K Kumar R | 1994 | Maize Genet Coop News Lett1994，68，： | 1 |
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