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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Non-destructive method of leaf-area determination in ash gourd ( Benincasa hispida) 显示文摘 | Radhakrishnan V V Kumar P G S Oommen A | 1991 | Indian Journal of Agricultural Sciences1991，61，1： | 1 |
| 3 | Performance of a magnesium-lithium alloy as an anode for magnesium batteries显示文摘 | SIVASHANMUGAM A KUMAR T P RENGANATHAN N G | 2004 | J Appl Electrochem2004，34，： | 1 |
| 4 | Characterization and 3D structure prediction of chitinase induced in sugarcane during pathogenesis of Colletotrichum falcatum显示文摘 | Rahul P R Kumar V G Sathyabhama M | | 0，，： | 1 |
| 5 | On the performance of stabilized a-nickel hydroxide as a nickel-positive electrode in alkaline storage batteries 显示文摘 | KUMAR V G MUNICHANDRAIAH N KAMATH P V SHUKLA A K | 1995 | Journal of Power Sources1995，56，： | 1 |
| 6 | Endoluminal ultrasonography with reusableprobe: preliminary reusult显示文摘 | KUMAR P V JOSHI H B TIMONEY A G | 2002 | J Endourol2002，16，： | 1 |
| 7 | Low temperature wet etching to reveal sub-surface damage in sapphire substrates显示文摘 | KUMAR P LEE J LEE G | 2013 | Applied Surface Science2013，，273： | 1 |
| 8 | Microstructural coarsening in Sn-Ag-based solders and its effects on mechanical properties显示文摘 | DUTTA I KUMAR P SUBBARAYAN G | 2009 | Journal of the Minerals Metals and Materials Society2009，61，6： | 1 |
| 9 | Behavior of lead borosilicate glass/alumina composite in the temperature range 900-1 100 ℃显示文摘 | Kumar K P Mukherjee P S Mukunda P G | 1989 | Materials Science & Engineering B:Solid-State Materials for Advanced Technology1989，5，1： | 1 |
| 10 | Silencing of acetylcholinesterase gene of Helicoverpa armigera by siRNA affects larval growth and its life cycle显示文摘 | Kumar M Gupta G P Rajam M V | | 0，，03： | 1 |
| 11 | Three-Dimensional Simulation of Multistage Depressed Collectors on Micro- Computers显示文摘 | Kumar L Spadtke P Carter R G | 1995 | IEEE Trans Electron Dev1995，42，9： | 1 |
| 12 | (2D)2 LDA: An efficient approach for face recognition 显示文摘 | Noushath S Hemantha Kumar G Shiva kumara P | 2006 | Pattern Recognition2006，39，7： | 1 |
| 13 | Cyclic codes over Z4,locator polynomials,and Newton's identities显示文摘 | Calderbank A R Mcguire G Kumar P V | 1996 | IEEE Trans Inform Theory1996，42，1： | 1 |
| 14 | Increase in the enantioselectivity of asymmetric hydrogenation in water influenced by surfactants or polymerized micelles显示文摘 | KUMAR A OEHME G ROQUE J P | 1994 | Angew Chem Int Ed Eng1994，33，： | 1 |
| 15 | Non-Darcy converging flow through coarse granular media 显示文摘 | PRADIP KUMAR G N VENKATARAMAN P | 1995 | Journal of the Institution of Engineers (India) : Civil Engineering Division1995，76，： | 1 |
| 16 | Mesenteric venous thrombosis 显示文摘 | Kumar S Sarr M G Kamath P S | 2001 | N Eng[J Med2001，345，9： | 1 |
| 17 | Assessing wetland eco- system services and poverty interlinkages: a general framework and case study 显示文摘 | Kumar R Horwitz P Milton G R | 2011 | Hydrological Sciences Journal2011，56，8： | 1 |
| 18 | Optimization of Microwave T-junction Power- Divider Circuits 显示文摘 | KUMAR P B BRANNER G R RAZMA F G | 1994 | Circuits and Systems1994，37，2： | 1 |
| 19 | RSC Advance显示文摘 | Sabitha G Reddy D V Reddy S S S Yadav J S Kumar C G Sujitha P | 2012 | 2(8):72412012，2，8： | 1 |
| 20 | EphB1 receptor tyrosine kinase is expressed in bladder cancer and pro vides signals for cell survival显示文摘 | Xia G Kumar S R Stein J P | 2006 | Oncogene2006，25，5： | 1 |
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