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| 1 | 患者肠道微生物群失调与肠上皮屏障功能障碍显示文摘最近的证据表明,在动物模型中,肠道病理学和微生物组与高血压之间存在联系。然而,这种关联在人类中是否存在尚不清楚。因此,该研究的目的是检验高血压患者具有明显特异的肠道微生物组以及肠上皮屏障功能标记物和微生物组组成可以预测收缩压变化的假设。研究者通过鸟枪法宏基因组学分析粪便样本显示微生物分类和功能变化,结果显示高血压患者和对照受试者之间丁酸盐产生存在差异。 | Kim S Goel R Kumar A Qi Y Lobaton G Hosaka K Mohammed M Handberg EM Richards EM Pepine CJ Raizada MK 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 45 |
| 2 | Perspectives of pluripotent stem cells in livestock显示文摘The recent progress in derivation of pluripotent stem cells(PSCs)from farm animals opens new approaches not only for reproduction,genetic engineering,treatment and conservation of these species,but also for screening novel drugs for their efficacy and toxicity,and modelling of human diseases.Initial attempts to derive PSCs from the inner cell mass of blastocyst stages in farm animals were largely unsuccessful as either the cells survived for only a few passages,or lost their cellular potency;indicating that the protocols which allowed the derivation of murine or human embryonic stem(ES)cells were not sufficient to support the maintenance of ES cells from farm animals.This scenario changed by the innovation of induced pluripotency and by the development of the 3 inhibitor culture conditions to support naïve pluripotency in ES cells from livestock species.However,the long-term culture of livestock PSCs while maintaining the full pluripotency is still challenging,and requires further refinements.Here,we review the current achievements in the derivation of PSCs from farm animals,and discuss the potential application areas. | Dharmendra Kumar Thirumala R Talluri Naresh L Selokar Iqbal Hyder Wilfried A Ku | 2021 | World Journal of Stem Cells2021，13，1： | 4 |
| 3 | 米糠油同时脱胶脱蜡物理精炼新技术显示文摘对米糠油同时脱胶脱蜡物理精炼新工艺进行了小试研究,并在此基础上进行了生产试验。毛米糠油与氯化钙水溶液混合,在低温下结晶(20℃)使水化磷脂和非水化磷脂与蜡一起沉析分离,随后进行脱色和冬化(20℃)处理,进一步将磷脂含量降到5mg/kg以下,再经物理精炼,即可使成品精炼米糠油满足市售商品对其色泽(10~12罗维朋值,25.4mm槽)、游离脂肪酸含量(〈0.25%)和浊点(4~5℃)的要求;且中性油损失少。米糠油含有多种生物活性物质,如谷维素,VE和甾醇。本工艺可在最终产品中保留80%以上的生物活性物质。 | Rajam L Soban Kumar D R Sundaresan A Arumughan C 武丽荣(译) | 2006 | 中国油脂2006，31，7： | 3 |
| 4 | 因拒食而由家庭成员对其鼻饲四年的精神分裂症和强迫症共病患者一例(英文)显示文摘在许多精神障碍中(包括强迫症和精神分裂症),拒食是常见的表现。当突然出现拒食时,这可能需要急诊处理;一旦变成慢性,它就成为一种难以改变的根深蒂固的行为。对拒食患者的诊断可能有难度,尤其是对有共病问题、智力受损或对自身状况缺乏自知力的患者。鼻饲是一种有效的短期干预方法,当患者重新进食时即可中止这一干预。然而,在某些情况下,患者可能变得依赖于鼻饲。我们介绍一个病例,报告一名患有精神分裂症、强迫症、边缘智力以及癫痫的患者由于拒绝进食而由其家庭成员用鼻饲管喂食超过三年。 | Sachdeva A Chandra M Saxena A Beniwal R Kandpal M Kumar A | 2015 | 上海精神医学2015，27，4： | 3 |
| 5 | Gastric hyperplastic polyps causing upper gastrointestinal hemorrhage in a young adult显示文摘Here, we report a case of a young man who presented with a significant upper gastrointestinal bleed treated by endoscopic removal of multiple hyperplastic polyps. Gastric hyperplastic polyps are a relatively uncommon cause of overt gastrointestinal bleeding. While most hyperplastic gastric polyps are asymptomatic, they may present with abdominal pain, iron def iciency anemia or gastric outlet obstruction. These polyps are associated with conditions such as Helicobacter pylori gastritis and atrophic autoimmune gastritis, which predispose the epithelium to chronic inf lammation and epithelial repair.The patient presented to Northwestern Memorial Hospital in July 2011. The polyps were resected by clip-assisted snare polypectomy. Histopathologic assessment of the resected polyps demonstrated multiple, nonulcerative hyperplastic polyps measuring 1.3-1.8 cm in size, without evidence of dysplasia or malignancy. This case describes a young adult patient with multiple, large gastric polyps causing overt gastrointestinal bleeding. This is a rare presentation in a young individual, as these polyps are typically identifi ed in patients older than 60 years of age and less commonly, pediatric populations. | Brian J Secemsky Kenika R Robinson Kumar Krishnan Kristina A Matkowskyj Barbara H Jung | 2013 | World Journal of Clinical Cases2013，1，1： | 2 |
| 6 | A comparison of seven soil P tests for plant species with different external P requirements grown on soils containing rock phosphate and superphosphate residues 显示文摘 | KUMAR V GILKES R J BOLLAND M D A | 1993 | Fertiliser Research1993，33，： | 1 |
| 7 | Co-immobilization of cholesterol oxidase and horseradish peroxidase in a sol-gel film显示文摘 | KUMAR A MALHOTRA R MALHOTRA B D | 2000 | Anal Chim Acta2000，414，： | 1 |
| 8 | Fluorodexoyglucose-PET in the management of breast cancer显示文摘 | Kumar R Alavi A | 2004 | Radiol Clin N Am2004，42，6： | 1 |
| 9 | Frequency Estimation Techniques for High Dynamic Trajectories显示文摘 | Vilnrotter V A Hinedi S Kumar R | 1989 | IEEE Trans on Aerospace and Electronic Systems1989，25，4： | 1 |
| 10 | Bewarel Fungal urosepsis may follow endoscopic intervention for prolonged indwelling ureteral stent显示文摘 | Gautam G Singh A K Kumar R | 2006 | J Endourol2006，20，7： | 1 |
| 11 | Low high density lipo- protein cholesterol: current status and future strategies for management 显示文摘 | Singh V Sharma R Kumar A | 2010 | Vasc Health Risk Manag2010，6，2： | 1 |
| 12 | Endobronchial tu- berculosis presenting as tumorous mass 显示文摘 | Singla R Kumar A Chauhan D | 2007 | Indian J Chest Dis Allied Sci2007，49，1： | 1 |
| 13 | Safety and efficacy of a superior caliceal puncture in pediatric percutaneous nephrolithotomy 显示文摘 | Anand A Kumar R Dogra PN | 2010 | JEndourol2010，24，11： | 1 |
| 14 | Transcathter closure of congenital ventricular septal defects:experience with various devices显示文摘 | Arora R Trehan V Kumar A | 2003 | Interw Cardiol2003，16，1： | 1 |
| 15 | Management of impacted upper ureteri calculi:Results of lithotripsy and percutaneous Litholapaxy显示文摘 | Srivastava A Ahlawat R Kumar A | 1992 | Br J Urol1992，70，： | 1 |
| 16 | 显示文摘 | Singh R Kumar J Kaur A | 2006 | Polymer2006，47，： | 1 |
| 17 | Transcatheter closure of congenital ventricular septal defects: experience with various devices显示文摘 | Arora R Trehan V Kumar A | 2003 | J Interv Cardiol2003，16，1： | 1 |
| 18 | DNA barcodes can distinguish species of Indian mosquitoes (Diptera: Culicidae)显示文摘 | Kumar N P Rajavel A R Natarajan R | 2007 | J Med Entomol2007，44，1： | 1 |
| 19 | Efficient and convenient polyethylene glyeol(PEG)-mediated synthesis of spiro-oxindoles显示文摘 | Meshram H M Kumar D A Prasad B R V | 2010 | Helvetica Chimica ACTA2010，93，4： | 1 |
| 20 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
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