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154篇 您的检索式：作者名="Kufe"

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	题名	作者	年代	出处	被引量
1	MUC1及其C端活性片段突变体具有抑制肿瘤的活性显示文摘MUC1蛋白翻译后成为一条多肽链,它很快在内质网被切割成2个亚基,形成稳定的异源二聚体.Cys-Gln-Cys(CQC)3个氨基酸位于MUC1C端亚基跨膜结构域与胞内结构域的连接处.研究发现,MUC1C端的CQCRRK结构域突变成AQARRK或使其缺失,突变体的致瘤性明显降低.表明:通过突变CQC→AQA来阻碍与C端亚基相关的二聚体化,可能成为肿瘤治疗的新途径.	魏玲易艳萍刘萱 DONALD KUFE 曹诚	2007	生物化学与生物物理进展2007，34，4：	2
2	Molecular targeting of gene therapy and radiotherapy 显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
3	Molecular targeting of gene therapy and radio therapy 显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
4	Interaction of human MUC1 and betacatenin is regulated by Lck and ZAP-70 in activated Jurkat T cell显示文摘	Li Q Ren J Kufe D	2004	Biochem Biophys Res Commun2004，315，2：	1
5	MUC1-C oncoprotein as a target in breast cancer: ac tivation of signaling pathways and therapeutic approaches 显示文摘	Kufe DW	2013	Oncogene2013，32，9：	1
6	MUCl oncoprotein stabilizes and activates estrogen receptor alpha显示文摘	Wei X Xu H Kufe D	2006	Mol Cell2006，21，2：	1
7	Molecular targeting of gene therapy and radiotherapy显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
8	Human MUC1 on coprotein regulates p53-responsive gene transcription in the genotoxic stress response显示文摘	Wei X Xu H Kufe D		0，，：	1
9	Mucins in cancer:function,prognosis andtherapy显示文摘	Kufe D	2009	Nat Rev Cancer2009，9，12：	1
10	Dendritic/Tumor Fusion Cells as Cancer Vaccines显示文摘	David Avigan Jacalyn Rosenblatt Donald Kufe	2012	Seminars in Oncology2012，，3：	1
11	Functional targeting of the MUC1 oncogene in human cancers 显示文摘	Kufe DW	2009	Cancer Biol Ther2009，8，13：	1
12	In vivo cytotoxicity of o- varian cancer cells through tumor - selective expression of the Bax gene显示文摘	Tai Y T Strobel T Kufe D	1999	Cancer Res1999，59，9：	1
13	Lenalidomide enhances anti-myeloma cellular immunity显示文摘	Katarina Luptakova Jacalyn Rosenblatt Brett Glotzbecker Heidi Mills Dina Stroopinsky Turner Kufe Baldev Vasir Jon Arnason Dimitri Tzachanis Jeffrey I. Zwicker Robin M. Joyce James D. Levine Kenneth C. Anderson Donald Kufe David Avigan	2013	Cancer Immunology, Immunotherapy2013，，：	1
14	Differential reactivity of a nove monoclonal antibody (DF3)with human maiignant Versus benign breast tumors显示文摘	KufeD InghiranuG AbeM etal	1984	Hybridoma1984，3，3：	1
15	Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft显示文摘	taba M J Maucefi H J Kufe D W	1998	Gene Ther1998，5，3：	1
16	MUC1 - C oncoprotein as a target in breast cancer: activa- tion of signaling pathways and therapeutic approaches显示文摘	Kufe DW	2013	Oncogene2013，32，9：	1
17	Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene 显示文摘	Wei X Xu H Kufe D	2007	Cancer Res2007，67，4：	1
18	Radiation-induced tumour necrosis factor-α expression:clinical application of transcriptional and physical targeting of gene therapy显示文摘	Weichselbaum RR Kufe DW Hellman S	2002	Lancet Oncol2002，3，11：	1
19	Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function显示文摘	Kufe DW Munroe D Herrick D	1984	Mol Pharmacol1984，26，1：	1
20	Functional targeting of the MUCI oncogene in human cancers显示文摘	Kufe DW	2009	Cancer BioI Ther2009，8，13：	1

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