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151篇 您的检索式:作者名="Krishnasamy"
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1Anti-chikungunya activity of luteolin and apigenin rich fraction from Cynodon dactylon显示文摘Objective:To obtain Iuteolin and apigenin rich fraction from the ethanolic extract of Cynodon dactylon(L.)(C.dactylon) Pers and evaluate the fraction's cytotoxicity and anti-Chikungunya potential using Vero cells.Methods:The ethanolic extract of C.dactylon was subjected to silica gel column chromatography to obtain anti-chikungunya virus(CHIKV) fraction.Reverse phase-HPLC and GC-MS studies were carried out to identily the major phytochemicals in the fraction using phylochemical standards.Cytotoxicity and the potential of the fraction against CHIKV were evaluated in vitro using Vero cells.Reduction in viral replication was assessed by reverse transcriptase-polymerase chain reaction(RT-PCR) after treating the viral infected Vero cells with the fraction.Results:Reverse Phase-HPLC and GC-MS studies confirmed the presence of flavonoids,luteolin and apigenin as major phytochemicals in the anti-CHIKV ethanolic fraction of C.dactylon- The fraction was found to exhibit potent viral inhibitory activity(about 98%) at the concentration of 50 μg/mL as observed by reduction in cytopathic effect,and the cytotoxic concentration of the fraction was found to be 250 μg/mL.RT-PCR analyses indicated that the reduction in viral mRNA synthesis in fraction treated infected cells was much higher than the viral infected control cells.Conclusions:Luteolin and apigenin rich ethanolic fraction from C.dactylon can be utilized as a potential therapeutic agent against CHIKV infection as the fraction does not show cytotoxicity while inhibiting the virus.Krishnan Saravana Murali Srinivasan Sivasubramanian Savariar Vincent Shanmugaraj Bala Murugan Bupesh Giridaran Sundaram Dinesh Palani Gunasekaran Kaveri Krishnasamy Ramalingam Sathishkumar 2015Asian Pacific Journal of Tropical Medicine2015,8,5:5
2Supramolecular Nanohelix Fabricated by Pillararene-Based Host–Guest System for Chirality Amplification, Transfer, and Circularly Polarized Luminescence in Water显示文摘Amplified chirality and Förster resonance energy transfer(FRET)-assisted chirality transfer frommolecular to nanoscale level have been shown to play a vital role in co-assembled nanohelix for potential energy transfer in biological systems.Herein,we have constructed a chiral host–guest complex donor system for chiral amplification via induced chirality of pillar[5]arene host and loaded it with an achiral dye acceptor to demonstrate how chirality-assisted excitation energy transfer occurred in the supramolecular nanohelix system in an aqueous medium.Krishnasamy Velmurugan Adil Murtaza Azhar Saeed Jianing Li Kaiya Wang Minzan Zuo Qian Liu Xiao-Yu Hu 2022CCS Chemistry2022,4,10:3
3Low Pressure DC Glow Discharge Air Plasma Surface Treatment of Polyethylene (PE) Film for Improvement of Adhesive Properties显示文摘The present work deals with the change in surface properties of polyethylene (PE) film using DC low pressure glow discharge air plasma and makes it useful for technical applications. The change in hydrophilicity of the modified PE film surface was investigated by measuring contact angle and surface energy as a function of exposure time. Changes in the morphological and chemical composition of PE films were analyzed by atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). The improvement in adhesion was studied by measuring T-peel and lap-shear strength. The results show that the wettability and surface energy of the PE film has been improved due to the introduction of oxygen-containing polar groups and an increase in surface roughness. The XPS result clearly shows the increase in concentration of oxygen content and the formation of polar groups on the polymer surface. The AFM observation on PE film shows that the roughness of the surface increased due to plasma treatment. The above morphological and chemical changes enhanced the adhesive properties of the PE film surfaces, which was confirmed by T-peel and lap-shear tests.Krishnasamy NAVANEETHA PANDIYARAJ Vengatasamy SELVARAJAN Rajendrasing R. DESHMUKH Coimbatore. Paramasivam YOGANAND Suresh BALASUBRAMANIAN Sundaram MARUTHAMUTHU 2013Plasma Science and Technology2013,15,1:2
4The prevalence of weight loss during (chemo)radiotherapy treatment for lung cancer and associated patient- and treatment-related factors显示文摘Nicole Kiss Elisabeth Isenring Karla Gough Meinir Krishnasamy 2013Clinical Nutrition2013,,:2
5Assessment of weather induce transmission line loads on a probabilistic basis显示文摘KRISHNASAMY S G 1985IEEE Trans on Power Apparatus and Systems1985,104,9:1
6The Effect of Nutrition Intervention in Lung Cancer Patients Undergoing Chemotherapy and/or Radiotherapy: A Systematic Review显示文摘NicoleK. Kiss Meinir Krishnasamy ElisabethA. Isenring 2014Nutrition and Cancer2014,,1:1
7Side chain alkylation of toluene with isopropanol and methanol over alkali exchanged zeolites显示文摘Kumari Vasanthy B Palanichamy M Krishnasamy V 1996Applied Catalysis A:General1996,148,:1
8Management of hemodialysis catheter related bacteremia with an adjunctive antibiotic lock solution显示文摘Krishnasami Z Carlton D Bimbo L 2002Kidney Int2002,61,3:1
9A general algorithm for the numerical solution of hyper-singular boundary integral equations 显示文摘Guiggiani M Krishnasamy G Rudolphi T J 1992ASME Journal of Applied Mechanics1992,59,:1
10Patient expectations and preferences for follow - up after treatment for lung cancer: Apilot study 显示文摘Krishnasamy M K Uqalde A Carey M 2010Eur J Nurs2010,15,3:1
11Exploring the nature and impact of fa- tigue in advanced cancer显示文摘Krishnasamy M 1997Int J Palliati Nurs1997,,3:1
12Side chain alkylation of toluene with isopropanol and methanol over alkaliexchanged zeolites显示文摘Kumari Vasanthy B Palanichamy M Krishnasamy 1996Applied Catalysis A: General1996,148,:1
13Management of hemodialy sis catheter related -bacteremia with an adjunctive antibiotic lock solution显示文摘Krishnasami Z Carlton D Bimbo L 2002Kidney Int2002,61,3:1
14Management of hemodialysis catheter-related bacteremia with an adjunctive antibiotic lock solution.显示文摘Krishnasami Z Carlton D Bimbo L 0,,:1
15Daily variation in death in patients treated by long-term dialysis:Comparison of in-center hemodialysis to peritoneal and home hemodialysis显示文摘Krishnasamy R Badve SV Hawley CM 0,,01:1
16Short communication:Susceptibility of Culex sitiens to Japanese encephalitis virus in peninsular Malaysia显示文摘I Vythilingam S B Tan M Krishnasamy 0,,:1
17Organ-specific reduction in the abundance of a mitochondrial protein accompanies fertility restoration in cytoplasmic male-sterile radish显示文摘Krishnasamy S Makaroff C A 1994Plant Molecular Biology1994,26,3:1
18Management of hemodialysis catheter-related bacteremia with an adjunctive antibiotic lock solution显示文摘Krishnasami Z Carlton D Bimbo L 2002Kidney Int2002,61,3:1
19Delay-Dependent Stability of Neutral Systems with Time-Varying Delays Using Delay-Decomposition Approach显示文摘Balasubramaniam P Krishnasamy R Rakkiyappan R 2012Applied Mathematical Modelling2012,36,5:1
20Rhabdomyolysis: not a textbook case显示文摘Sunit- Preet Chaudhry Kavita Krishnasamy 2012Am J Medicine2012,125,2:1
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