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15篇 您的检索式：作者名="Kosone"

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		题名	作者	年代	出处	被引量
	1	Overexpression of NK2 inhibits liver regeneration after partial hepatectomy in mice显示文摘AIM: To investigate the in vivo effects of NK2 on liver regeneration after partial hepatectomy (PH). METHODS: Survival after PH was observed with 21 NK2 transgenic mice and 23 wild-type (WT) mice over 10 d. Liver regeneration was analyzed using histology and immunohistochemistry. Expressions of genes were analyzed using Northern blot analysis, immunoprecipitation and immunoblotting, and reverse transcriptase polymerase chain reaction assay. KaplanMeier method and the log-rank test were used for ahalyzing the survival after PH. Differences in the resultsof immunohistochemistry and percentage of liver regeneration was determined by the Student's t-test. RESULTS: More than half of NK2 transgenic mice died within 48 h after PH. After PH, increased deposition of small lipid droplets in hepatocytes was evident and hepatic proliferation was inhibited in NK2 transgenic mice. The hepatic expression and kinase activity of HGF receptor, c-Met, were unchanged among WT mice and NK2 transgenic mice after PH. The expression of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in liver tissues were prolonged in NK2 transgenic mice that died after PH.CONCLUSION: Our findings indicate that overexpression of NK2 inhibits liver regeneration after PH.	Toshiyuki Otsuka Norio Horiguchi Daisuke Kanda Takashi Kosone Yuichi Yamazaki Kazuhisa Yuasa Naondo Sohara Satoru Kakizaki Ken Sato Hitoshi Takagi Glenn Merlino Masatomo Mori	2005	World Journal of Gastroenterology2005，11，47：	2
	2	Short-term complications of retrograde transvenous obliteration of gastric varices in patients with portal hypertension: effects of obliteration of major portosystemic shunts显示文摘	R. Shimoda K. Horiuchi S. Hagiwara H. Suzuki Y. Yamazaki T. Kosone T. Ichikawa H. Arai T. Yamada T. Abe H. Takagi M. Mori	2005	Abdominal Imaging2005，，3：	1
	3	Marked eosinophilia as the first manifestation of selerosing eholangitis显示文摘	Horiuehi K Kakizaki S Kosone T	2009	Inter Med2009，48，16：	1
	4	Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic Steatohepatitis 显示文摘	Tojima H Kakizaki S Kosone T	2011	Hepatol Int2011，6，3：	1
	5	Hepatocyte growth factor accelerates thrombopoiesis in transgenic mice 显示文摘	Kosone T Takagi H Horiguchi N	2007	Lab Invest2007，87，3：	1
	6	Innovation:Exploring the knowledge base显示文摘	Jan Fagerberg Morten Fosaas Koson Sapprasert	2012	R esearch Policy2012，41，7：	1
	7	Transforming growth factor-alpha accelerates hepatocyte repopulation after hepatocyte transplantation显示文摘	Kosone T Takagi H Horiguchi N	2008	Gastroenterol Hepatol2008，23，2：	1
	8	Synthesis, crystal structures,magnetic properties and fluorescent emissions of two-di- mensional bimetallic coordination frameworks Fell (3-fluoropyridine) 2 显示文摘	KOSONE T KANADANI C SAlT O	2009	Polyhedron2009，28，910：	1
	9	Short-term complications of retrograde transvenous obliteration of gastric varices in patients with portal hypertension: effects of obliteration of major portosystemic shunts显示文摘	R. Shimoda K. Horiuchi S. Hagiwara H. Suzuki Y. Yamazaki T. Kosone T. Ichikawa H. Arai T. Yamada T. Abe H. Takagi M. Mori	2005	Abdominal Imaging2005，，3：	1
	10	The hunt for dying neurons:insight into the neuronal loss in Alzheimer' s disease 显示文摘	Zilkova M Koson P Zilka N	2006	Bratisl Lek Listy2006，107，910：	1
	11	Antecedentsof an experienced sense of virtual community显示文摘	Tonteri L Kosone M Ellonen	2011	H-K Tarkiainen:Computers in Human Behavior2011，，27：	1
	12	Leaf contents differ depending on the position in rice leaf sheath during sink-source transition显示文摘	Ishimaru K Kosone M Sasaki H	2004	Plant Physiology and Biochemistry2004，42，：	1
	13	Gene expression profiles of drag-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor显示文摘	Kakizaki S Yamazaki Y Kosone T	2007	Liver Int2007，27，1：	1
	14	Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis显示文摘	Tojima H Kakizaki S Kosone T	2012	Hepatology International2012，6，：	1
	15	The hunt for dying neurons: insight into the neuronal loss in Alzheimer's disease 显示文摘	Zilkova M Koson P Zilka N	2006	Bratisl Lek Listy2006，107，910：	1

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