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| 1 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment. | Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren | 2014 | World Journal of Radiology2014，6，7： | 8 |
| 2 | Autotrophic denitrification of landfill leachate using elemental sulphur显示文摘 | KOENING A LIU L H | 1996 | Wat Sci Tech1996，34，56： | 2 |
| 3 | Disruption of functional connectivity in clinically normal older adults harboring amyloid burden显示文摘 | Trey H Koene RA van Alex B | 2009 | Neurosci2009，29，40： | 1 |
| 4 | Breakthrough Innovation Dilemmas显示文摘 | Koen P A Bertels H Elsum I R | 2010 | Research Technology Management2010，53，6： | 1 |
| 5 | Autotrophic denitrification of landfill leachate using elemental sulphur显示文摘 | Koening A Liu L H | 1996 | Water Science Technolo- gy1996，34，56： | 1 |
| 6 | Dutch guideline for the diagnosis and treatment of immune thrombocytopenia in adults显示文摘 | Schipperus MR Koene H Zwaginga J J | | 0，，10： | 1 |
| 7 | Prognostic factors in idiopathic membranous nephropathy 显示文摘 | Reichert H Koene RA Wetzels JF | 1998 | Am J Kidney Dis1998，31，1： | 1 |
| 8 | Dutch guideline for the diagnosis and treatment of immune thrombocytopenia in adults显示文摘 | Schipperus MR Koene H Zwaginga JJ | 2010 | Nederlands Tijdschrift voor Hematologie2010，7，10： | 1 |
| 9 | Combining top - down and bottom - up dynamics in land use modeling: exploring the future of abandoned farmlands in Europe with the Dyna - CLUE model 显示文摘 | VER BURG P H KOEN P O | 2009 | Landscape Ecology2009，24，9： | 1 |
| 10 | Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes 显示文摘 | Hajovsky H Hu G Koen Y | 2012 | Chem Res Toxicol2012，25，9： | 1 |
| 11 | Lipoprotein-associated phospholipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population:results from the 14-year follow-up of a large cohort from southern Germany显示文摘 | KOENING W KHUSEYINOVA N LOWEL H | | 0，，14： | 1 |
| 12 | Abnormal cotrisol secretion and responses to corticotropin - releasing hormone in women with hypo- thalamic amenorrhea 显示文摘 | Billet E M Federoff H J Koening J l | 1990 | JClin Endocrinol Metab1990，70，2： | 1 |
| 13 | Top-spray fluidized bed coating :effect of process variables on coating efficiency 显示文摘 | Koen D Andre H | 1998 | Lebensm-Wiss Technol1998，31，6： | 1 |
| 14 | Physical therapy activities in stroke,knee Arthroplasty,and traumatic brain injury rehabilitation:their variation,similarities,and association with functional outcomes显示文摘 | Gerben D Ching-Hui H Koen P | 2011 | Phys Ther2011，91，12： | 1 |
| 15 | Microfoundations of Routines and Capabilities: In- dividuals, Processes, and Structure 显示文摘 | Teppo Felin Nicolai J Foss Koen H Heimeriks Tammy L Madsen | 2012 | Journal of Manage- ment Studies2012，49，8： | 1 |
| 16 | Physical Therapy Activ- ities in Stroke, Knee Arthroplasty,and Traumatic Brain Injury Rehabilitation: Their Variation, Similarities, and Association With Functional Outeomes显示文摘 | Gerben D Ching-Hui H Koen P | 2011 | Phys Ther2011，91，12： | 1 |
| 17 | Thwarting of behaviour in different contexts and the gakel-call in the laying hen显示文摘 | Zimmerman P H Koene P van Hooff J | | 0，，04： | 1 |
| 18 | The vocal expression of feeding motivation and frustration in the domestic laying hen,Gallus gallus domesticus显示文摘 | Zimmerman P H Koene P van Hooff J | | 0，，04： | 1 |
| 19 | Knowledge, Attitudes and Practices in Travel-related Infectious Diseases: The European Airport Survey显示文摘 | Koen Iran H Francesco C Jane C | 2004 | Journal of travel medicine2004，11，： | 1 |
| 20 | Association between plasma viscosity and all-cause mortality:results from the MONIC-Ausburg cohort study显示文摘 | Koening W Sund M Lowel H | 2000 | Br J Haematol2000，109，： | 1 |
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