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| 1 | Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism显示文摘 | Fu YS Cheng YC Lin MY Cheng H Chu PM Chou SC Shih YH Ko MH Sung MS | 2006 | 中国生物学文摘2006，20，10： | 138 |
| 2 | Pancreatic enzymes and abdominal adipose tissue distribution in new-onset prediabetes/diabetes after acute pancreatitis显示文摘BACKGROUND New-onset prediabetes/diabetes after acute pancreatitis(NODAP)is the most common sequela of pancreatitis,and it differs from type 2 prediabetes/diabetes mellitus(T2DM).AIM To study the associations between circulating levels of pancreatic amylase,pancreatic lipase,chymotrypsin and fat phenotypes in NODAP,T2DM,and health.METHODS Individuals with NODAP(n=30),T2DM(n=30),and sex-matched healthy individuals(n=30)were included.Five fat phenotypes(intra-pancreatic fat,liver fat,skeletal muscle fat,visceral fat,and subcutaneous fat)were determined using the same magnetic resonance imaging protocol and scanner magnet strength for all participants.One-way analysis of covariance,linear regression analysis,and relative importance analysis were conducted.RESULTS Intra-pancreatic fat deposition(IPFD)was higher in NODAP(9.4%±1.8%)and T2DM(9.8%±1.1%)compared with healthy controls(7.8%±1.9%)after adjusting for covariates(P=0.003).Similar findings were observed in regards to visceral fat volume(P=0.005),but not subcutaneous fat volume,liver fat,or skeletal muscle fat.Both IPFD(β=-2.201,P=0.023)and visceral fat volume(β=-0.004,P=0.028)were significantly associated with circulating levels of pancreatic amylase in NODAP,but not in T2DM or healthy individuals.Of the five fat phenotypes,IPFD explained the highest amount of variance in pancreatic amylase concentration(R2=15.3%out of 41.2%).None of the phenotypes contributed meaningfully to the variance in pancreatic lipase or chymotrypsin.CONCLUSION Both NODAP and T2DM are characterized by increased IPFD and visceral fat volume.However,only NODAP is characterized by significant inverse associations between the two fat phenotypes and pancreatic amylase. | Juyeon Ko Loren Skudder-Hill Jaelim Cho Sakina H Bharmal Maxim S Petrov | 2021 | World Journal of Gastroenterology2021，27，23： | 5 |
| 3 | Beyond first-line chemotherapy for advanced pancreatic cancer:An expanding array of therapeutic options?显示文摘While an increasing number of therapeutic options are now available for the first-line treatment of locally advanced or metastatic pancreatic cancer,the optimal choice for treatment in the second-line setting and beyond is less well defined.A variety of cytotoxic agents,either alone or in combination,have been evaluated,although primarily in the context of small single-arm or retrospective studies.Most regimens have been associated with median progression-free survival rates in the range of 2-4 mo and overall survival rates between 4-8mo,highlighting the very poor prognosis of patients who are candidates for such treatment.Targeted therapies studied in this chemotherapy-refractory setting,meanwhile,have produced even worse efficacy results.In the current article,we review the clinical evidence for treatment of refractory disease,primarily in patients who have progressed on front-line gemcitabine-based chemotherapy.In the process,we highlight the limitations of the available data to date as well as some of the challenges in designing appropriate clinical trials in this salvage setting,including how to select an appropriate control arm given the absence of a wellestablished reference standard,and the importance of incorporating predictive biomarkers and quality of life measures whenever possible into study design. | Evan J Walker Andrew H Ko | 2014 | World Journal of Gastroenterology2014，20，9： | 2 |
| 4 | Location-aided routing (LAR) in mobile Ad Hoc network 显示文摘 | Ko Y B Vaidya N H | 2000 | IEEE Wireless Networks2000，6，： | 2 |
| 5 | 由木炭角菌引起的澳洲坚果速衰病显示文摘在夏威夷群岛的一个经济果园中发现了澳洲坚果速衰病,其症状为在树干上出现木炭角菌(Xylaria abuscula)棍棒状的子实体。从发病的木质部中可分离到木炭角菌。如果将该菌接种于健康的澳洲坚果树上,它可使树枝致死。树干受该菌侵染后可引起环状坏死,结果澳洲坚果树衰退的速度比其根部受到土居病原菌侵染的哀退速度更快。 | W H Ko 林文有 | 1993 | 广西热作科技1993，，1： | 2 |
| 6 | Human autoantibodies to carcinoembryonic antigen (CEA) induced by a vaccinia-CEA vaccine 显示文摘 | Conry RM Allen KO Lee H | 2000 | ClinCancer Res2000，6，1： | 2 |
| 7 | Artificial neural- network based feeder reconfiguration for loss reduction in distribution systems显示文摘 | Kim H Ko Y Jung K-H | 1993 | IEEE Trans onPowerDelivery1993，8，3： | 2 |
| 8 | Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in P53 stabilization显示文摘 | KO J LEE Y H HWANG S Y | 2003 | Oncogene2003，22，： | 1 |
| 9 | A new LDA-based face recognition system which can solve the small sample size problem显示文摘 | CHEN LF LIAO H Y M KO M T | 2000 | Pattern Recognition2000，33，10： | 1 |
| 10 | Field - amplified sample stacking in capillary electrophoresis for the determination of clozapine, clozapine N - oxide, anddesmethylclozapine in schizophrenics' plasma显示文摘 | Ho Y H Ko W K Kou W S | 2004 | Journal of Chromatography B2004，809，： | 1 |
| 11 | On the Complete Convergence for Weighted Sums of Dependent Random Variables under Condition of Weighted Integrability 显示文摘 | Baek J I Ko M H Kim T S | 2008 | J Korean Math Soc2008，45，1： | 1 |
| 12 | Improved enzymatic hydrolysis yield of rice straw using electron beam irradiation pretreatment显示文摘 | Bak J S Ko J K Han Y H | 2009 | Bioresource Technology2009，100，： | 1 |
| 13 | The expression of porcine adiponectin and stearoyl coenzyme Adesaturase genes in differentiating adipocyte 显示文摘 | Wang P H Ko Y H B Liu H H | 2004 | J Anita Sci2004，17，： | 1 |
| 14 | Structure-borne noise reduction for an infinite,elastic cylindrical shell显示文摘 | KO S H SEONG W PYO S | 2001 | Journal of the Acoustical Society of America2001，109，4： | 1 |
| 15 | A fuzzy nonlinear model for quality function deployment considering Kano's concept 显示文摘 | Chen L H Ko W C | 2008 | Mathematical and Computer Modeling2008，48，34： | 1 |
| 16 | Vasorelaxant and antiproliferative effects of berberine 显示文摘 | Ko W H Yao X Q Lau C W | 2000 | Eur J Pharrnacol2000，399，23： | 1 |
| 17 | Agenetie algorithm approach to developing the multi - echelon reverse logistics network for product returns显示文摘 | Min H Ko H J Ko C S | 2006 | Omega2006，34，： | 1 |
| 18 | Novel molecular drug carrier:Encapsulation of oxaliplatin in cucurbit uril and its effects on stability and reactivity of the drug显示文摘 | JEON Y J KIM S Y KO Y H | 2005 | Org Biomol Chem2005，3，11： | 1 |
| 19 | Digital image stabilizing algorithms based on bit-plane matching 显示文摘 | Ko S J Lee S H Lee K H | 1998 | IEEE Transactions on Consumer Electronics1998，44，3： | 1 |
| 20 | Automatic assembling procedure generation from mating conditions 显示文摘 | Ko H Lee K | 1987 | Computer-Aided Design1987，19，1： | 1 |
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