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| 1 | Condyloma acuminatum of the anal canal,treated with endoscopic submucosal dissection显示文摘Condyloma acuminatum(CA) is a common sexually transmitted disease caused by human papilloma virus infection. Not all individuals develop persistent, progressive disease, but careful follow up is required with moderate-to-severe dysplasia to prevent progression to malignancy. Standard therapies include surgical treatments(trans-anal resection and transanal endoscopic microsurgery) and immunotherapeutic and topical methods(topical imiquimod); however, local recurrence remains a considerable problem. Here, we report a case with superficial CA of the anal canal, treated with endoscopic submucosal dissection(ESD). A 28-year-old man presented with a chief complaint of hematochezia. Digital exam did not detect a tumor. Screening colonoscopy revealed 10-mm long, whitish condyles extending from the anal canal to the lower rectum. The lesion covered almost the whole circumference, and only a small amount of normal mucosa remained. Magnifying endoscopy with narrow band imaging showed brownish hairpin-shaped, coiled capillaries. Although histopathological diagnosis by biopsy revealed CA, accurate histological differentiation between CA, papilloma, and squamous cell carcinoma can be difficult with a small specimen. Therefore, weperformed diagnostic ESD, which provides a complete specimen for precise histopathological evaluation. The pathological diagnosis was CA, with moderate dysplasia(anal intraepithelial neoplasia 2). There was no recurrence at 16 mo after the initial ESD. Compared to surgical treatment, endoscopic diagnosis and resection could be performed simultaneously and the tumor margin observed clearly with a magnifying chromocolonoscopy, resulting in less recurrence. These findings suggest that endoscopic resection may be an alternative method for CA that prevents recurrence. | Akiko Sasaki Takeshi Nakajima Hideto Egashira Kotaro Takeda Shinnosuke Tokoro Chikamasa Ichita Sakue Masuda Haruki Uojima Kazuya Koizumi Takeshi Kinbara Taku Sakamoto Yutaka Saito Makoto Kako | 2016 | World Journal of Gastroenterology2016，22，8： | 11 |
| 2 | TiN film coatings on alumina radio frequency windows显示文摘 | Michizono S Kinbara A Saito Y | 1992 | J Vac Sci Technol1992，10，4： | 1 |
| 3 | Process effects on structural properties of TiO2 thin films by reactive sputtering显示文摘 | WIEAKSANA D KOBAYASHI A KINBARA A | 1992 | Journal of Vacancy Science and Technology A1992，，10： | 1 |
| 4 | Effect of sodium tauroursodeoxycholate on phalloidin-induced cholestasis in rats显示文摘 | Ishizaki K Kinbara S Hirabayashi N | 2001 | Eur J Pharmacol2001，421，1： | 1 |
| 5 | Effect of cholecystokinin 1 receptor antagonistloxiglumide (CR1505) on basal pancreatic exocrine secretion in consciousrats显示文摘 | Ishizaki K Kinbara S Kawamura M | 2003 | Pancreas2003，26，1： | 1 |
| 6 | Muscle-specific Calpain, p94, responsible for limb girdle muscular dystrophy type 2A asso- ciates with connection thmugt~ IS2, a p94 specific sequence显示文摘 | Sorimachi H Kinbara K Kimura S ct al | 1995 | Journal of Biological Chemistry1995，270，31： | 1 |
| 7 | Ras GTPases: integrins' friends or foes? 显示文摘 | Kinbara K Goldfinger LE Hansen M | 2003 | Nat Rev M01 Cell Biol2003，4，10： | 1 |
| 8 | An autopsy case of tako - tsubocardiomyopathy presenting ventricular tachycardia after pacemaker im-plantation显示文摘 | Kinbara T Hayano T Otani N | 2013 | J Cardiol Casas2013，8，4： | 1 |
| 9 | Skeletal muscle-specific calpain,p94:Structure and physiological function显示文摘 | KINBARA K SORIMACHI H ISHIURA S | 1998 | Biochem Pharmacol1998，56，4： | 1 |
| 10 | A laboratory simulation for stick-slip phenomena on the hydraulic cylinder of a construction machine显示文摘 | Muraki M Kinbara E Konishi T | 2003 | Tribology International2003，36，10： | 1 |
| 11 | Percutaneous radiofrequency ablation with transarterial embolization is useful for treatment of stage 1 renal cell carcinoma with surgical risk:results at 2-year mean follow up显示文摘 | Arima K Yamakado K Kinbara H | 2007 | Int J Urol2007，14，7： | 1 |
| 12 | Elastic and plastic energies in sputtered multilayered Ti–TiN films estimated by nanoindentation显示文摘 | Naoto Kikuchi Masaru Kitagawa Akishige Sato Eiji Kusano Hidehito Nanto Akira Kinbara | 2000 | Surface & Coatings Technology2000，，2： | 1 |
| 13 | Transforming growth factor-beta isoforms differently stimulate proalpha2 (I) collagen gene expression during wound healing process in transgenic mice 显示文摘 | Kinbara T Shirasaki F Kawara S | 2002 | J Cell Physiol2002，190，3： | 1 |
| 14 | Skeletalmuscle-specific calpain,p94显示文摘 | KINBARA K SORIMACHI H ISHIURA S | 1998 | Biochem Phamacol1998，56，： | 1 |
| 15 | Skeletal muscle specific calpain, p94 显示文摘 | Kinbara K Sorimachi H lshiura S | 1998 | Biochem Pharmacol1998，56，： | 1 |
| 16 | 显示文摘 | Nishiura N Yoshida S Kinbara A | 1973 | Thin Solid Films1973，15，： | 1 |
| 17 | Work Function of Thin LaB6 Films显示文摘 | Akie Yutani Akihiko Kobayashi Akira Kinbara | 1993 | Applied Surface Science1993，7071，14： | 1 |
| 18 | Mechanical twisting of a guest by a photoresponsive host显示文摘 | TMuraoka Kinbara K Aida T | 2006 | Nature2006，440，： | 1 |
| 19 | Optical resolution of 1-(3-methoxyphenyl)ethylamine with enantiomerically pure mandelic acid,and the crystal structure of less-soluble diastereomeric salt显示文摘 | Sakai K Hashimoto Y Kinbara K | 1993 | Bull Chem Soc Jpn1993，66，11： | 1 |
| 20 | Discrimination of forearm's motions by surface EMG signals using neural network 显示文摘 | Itakura N Kinbara Y Fuwa T | 1996 | Appl Human Sci1996，15，6： | 1 |
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