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| 1 | 贻贝等六种软体动物磷脂的比较显示文摘对紫贻贝、栉孔扇贝、褶牡蛎、杂色蛤、缢蛏、毛蚶六种贝类的磷脂作了比较研究 ,对它们的出肉率、总脂、中性脂、极性脂、磷脂及其组分、脂肪酸的组成做了检测分析。结果表明 ,六种贝类的磷脂特性有一定的差异 ,牡蛎中磷脂酰肌醇含量特别高。心磷脂只在牡蛎和毛蚶中被检出 ,毛蚶中只含EPA ,而无DHA。六种贝类共同特点是磷脂酰胆碱与磷脂酰乙醇胺之和在 70 | 林洪 吕青 Khalid Jamil 薛长湖 欧阳昌荣 王海英 | 2000 | 水产学报2000，24，2： | 17 |
| 2 | 中国对虾肌动球蛋白变性后ATPase活性的研究显示文摘在中国对虾肌动球蛋白(Aotomyosin)经冷冻变性和热变性后,对Ca2+-ATPase、Mg2+-ATPase活性及蛋白质溶解度进行了研究。冷冻变性之后,肌动球蛋白Ca2+-ATPase活性呈逐渐下降趋势,一般贮藏温度越低,活性降低越快。热变性之后,肌动球蛋白Ca2+或Mg2+-ATPase活性都随温度升高而下降,但肌动球蛋白Ca2+或Mg2+-ATPase活性在35℃有一急剧下降的拐点,并分别在45℃、40℃附近低到0。由于蛋白质的变性。 | 林洪 王长峰 李兆杰 Khalid Jamil | 1996 | 青岛海洋大学学报(自然科学版)1996，26，4： | 14 |
| 3 | Anti-allergic effects of ethanol extracts from brown seaweeds显示文摘Ethanol extracts of brown seaweeds from Pakistan and China were isolated and compared for their antiallergenic activities. They included Sargassum tennerimum (ST) and Sargassum cervicorne (SC) from Pakistan, and Sargassum gramini- folium turn (SG), Sargassum thunbergii (STH), and Laminaria japonica (LJ) from China. The ethanol extracts of these brown seaweeds were optimized at 85% (v/v) ethanol for the maximum yield of phlorotannin, an inhibitor against hyaluronidase. Total phlorotannins contained in the crude extracts were measured as 1.71% (SG), 0.74% (STH), 0.97% (LJ), 3.30% (SC), and 5.06% (ST). The 50% inhibitory concentrations (IC50) of Pakistani SC and ST were 109.5 and 21 μg/ml, respectively, lower than those of Chinese SG, STH, and LJ (134, 269, and 148 μg/ml, respectively). An antiallergic drug, disodium cromoglycate (DSCG), had an IC50=39 μg/ml, and a natural inhibitor of hyaluronidase, catechin, had an IC50=20 μg/ml. The IC50 of ST extract was found similar to that of catechin (21 vs 20 μg/ml) and lower than that of DSCG (21 vs 39 μg/ml). This suggests that ST is a potent inhibitor of hyaluronidase, indicating a promising future development of natural antiallergic medicines or functional foods. | Haider SAMEE Zhen-xing LI Hong LIN Jamil KHALID Yong-chao GUO | 2009 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2009，10，2： | 6 |
| 4 | Studies on the Specific Degranulation of Mast Cell Sensitized by Several Allergens in vitro显示文摘Food allergy is a major health issue worldwide. Mast cells play a very important role in the immediate hypersensitivity for which mast cell degranulation needs to be studied extensively. In this study, an approach was taken to study the characteristics of sensitized mast cell degranulation in vitro, which associated with the study of mast cells and animal models. BALB/c mice were immunized respectively by several food allergens, then blood and peritoneal mast cells were collected at different time points. A dynamic determination was carried out between mast cells and serumal IgE. Comparative analysis on sequential time points showed that there was a close coincidence between mast cell degranulation and IgE antibody titers in sensitized BALB/c mice. Furthermore, it is interesting that sensitized mast cells could implement specific degranulation against the challenges in vitro, but the closely tropomyosins induced mast cell degranulation displayed cross reactions. This is very similar to IgE resisting the allergens in vivo. The study disclosed some characteristics on mast cells, coming from sensitized BALB/c mice, degranulation in vitro. | Yongchao Guo Zhenxing Li Hong Lin Haider Samee Jamil Khalid | 2009 | Cellular & Molecular Immunology2009，6，2： | 3 |
| 5 | Optimization of Preparative Separation and Purification of Total Polyphenols from Sargassum tenerrimum by Column Chromatography显示文摘Polyphenols from the ethanol extracts of Sargassum tenerrimum (ST) with potent antiallergic effects were studied to optimize separation process through column chromatography. The adsorption and desorption characteristics of three widely used adsorbents: macroporous resin, silica gel, and polyvinylpolypyrrolidone (PVPP), were critically evaluated respectively and studied for the optimization of preparative separation of polyphenols. Static operations on these adsorbents showed that macroporous resin had the best adsorption and desorption capability among the three adsorbents. Dynamic adsorption and desorption with macroporous resin packed column were also conducted to optimize the parameters such as: with the optimal values shown in brackets, the concentration of extract solution (4 times diluted), pH value (6?7), adsorption speed (3 BV h-1, bed volumes/per hour), concentration of ethanol (80%), elution speed (3 BV h-1) and elution volume (7 BV). The chromatographic process so optimized gave a purity of 62.43% from the crude polyphenols, providing a promising basis for large scale preparation of bioactive polyphenols upon further scaling up tests. | Samee Haider LI Zhenxing LIN Hong Khalid Jamil | 2009 | Journal of Ocean University of China2009，8，4： | 3 |
| 6 | Anti-allergic effects of ethanol extracts from brown seaweeds显示文摘 | Haider Samee Zhen-xing Li Hong Lin Jamil Khalid Yong-chao Guo | 2009 | Journal of Zhejiang University SCIENCE B2009，，2： | 1 |
| 7 | Clinical outcomes of moderate to severe COVID-19 patients receiving invasive vs. non-invasive ventilation显示文摘Objective:To evaluate the in-hospital outcome of moderate to severe COVID-19 patients admitted in High Dependency Unit(HDU)in relation to invasive vs.non-invasive mode of ventilation.Methods:In this study,the patients required either non-invasive[oxygen≤10 L/min or>10 L/min through mask or nasal prongs,rebreather masks and bilevel positive airway pressure(BiPAP)]or invasive ventilation.For analysis of 30-day in hospital mortality in relation to use of different modes of oxygen,Kaplan Meier and log rank analyses were used.In the end,independent predictors of survival were determined by Cox regression analysis.Results:Invasive ventilation was required by 15.1%patients while 84.9%patients needed non-invasive ventilation.Patients with evidence of thromboembolism,high inflammatory markers and hypoxemia mainly required invasive ventilation.The 30-day in hospital mortality was 72.7%for the invasive group and 12.9%for the non-invasive group(1.8%oxygen<10 L/min,0.9%oxygen>10 L/min,3.6%rebreather mask and 4.5%BiPAP).The median time from hospital admission to outcome was 7 days for the invasive group and 18 days for the non-invasive group(P<0.05).Age,presence of co-morbidities,number of days requiring oxygen,rebreather,BiPAP and invasive ventilation were independent predictors of outcome.Conclusions:Invasive mechanical ventilation is associated with adverse outcomes possibly due to ventilator associated lung injury.Thus,protective non-invasive ventilation remains the necessary and safe treatment for severely hypoxic COVID-19 patients. | Zubia Jamil Samreen Khalid Shahid Mumtaz Abbasi Yasir Waheed Jamal Ahmed | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，4： | 1 |
| 8 | Effects of Replacing Fishmeal with Animal By-products Meal Supplementation in Diets on the Growth and Nutrient Utilization of Mangrove Red Snapper显示文摘A feeding trial was conducted for 75 d to evaluate the nutritive value of a mixture of animal by-products(MAB) as a possible protein source in diets for juvenile mangrove red snapper,Lutjanus argentimaculatus(mean initial body weight,30 g). Fish were fed one of five isonitrogenous diets(40% crude protein) replacing 0,25%(MAB25),50%(MAB50),75%(MAB75) and 100%(MAB100) of fish meal protein with similar percentages of MAB. The MAB consisted of 25% cow liver meal,20% leather meal,20% meat and bone meal,15% blood meal,10% APC(poultry feather meal),8% poultry manure dried,1.5% choline and 0.5% chromic oxide. After 75 d of feeding,fish fed with diets MAB50,MAB75 and MAB100 exhibited significantly lower growth per-formance than that of fish fed with control and MAB25 diets. The optimum level of MAB was estimated to be 23%. Replacement of fish meal by MAB23% showed the following performance:maximum weight gain,510%;SGR,2.39% and FCE,2.83%. The MAB substitution up to 75% of fish meal protein in diets did not show differences in apparent protein digestibility(83.6% for MAB25,79.2% for MAB50,78.7% for MAB75) compared with control(83.4%),whereas in MAB100 group digestibility(65.3%) was sig-nificantly lower than in other groups. The apparent phosphorus absorption of test diet groups was significantly higher(37.1% for MAB25,28.5% for MAB50,55.6% for MAB75 and 54.5% for MAB100) than that of control(11.2%). The levels of protein and ash in the whole body,carcass and viscera increased as MAB substitution in diets increased,whereas lipids and moisture remained con-sistent among all treatment groups. These results showed that approximately 23% of fish meal protein could be replaced by a mixture of animal by-products for juvenile snapper growing from 30 g to 167 g in 75 d without compromising growth performance and feed efficiency. | Khalid Jamil Ghulam Abbas Rukhsana Akhtar LIN Hong LI Zhenxing | 2007 | Journal of Ocean University of China2007，6，3： | 1 |
| 9 | Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats显示文摘 | Sadiq Umar Jamil Zargan Khalid Umar Sayeed Ahmad Chandra Kant Katiyar Haider A. Khan | 2012 | Chemico-Biological Interactions2012，，1： | 1 |
| 10 | Effect of deposition parameters on structural and mechanical properties of niobium nitride synthesized by plasma focus device显示文摘Effects of deposition angle and axial distance on the structural and mechanical properties of niobium nitride synthesized by a dense plasma focus(DPF) system are studied.The x-ray diffraction(XRD) confirms that the deposition parameters affect the growth of multi-phase niobium nitride.Scanning electron microscopy(SEM) shows the granular surface morphology with strong thermally assisted coagulation effects observed at the 5-cm axial distance.The non-porous granular morphology observed at the 9-cm distance along the anode axis is different from those observed at deposition angles of 10°and 20°.Energy dispersive x-ray(EDX) spectroscopy reveals the maximum nitrogen content at the shortest(5 cm) axial position.Atomic force microscopy(AFM) exhibits that the roughness of coated films varies for coatings synthesized at different axial and angular positions,and the Vickers micro-hardness test shows that a maximum hardness value is(08.44 ± 0.01) GPa for niobium nitride synthesized at 5-cm axial distance,which is about 500% more than that of a virgin sample. | Jamil Siddiqui Tousif Hussain Riaz Ahmad Nida Khalid | 2015 | Chinese Physics B2015，24，6： | 0 |
| 11 | Predictors of complicated dengue infections in endemic region of Pakistan显示文摘Objective:To predict the factors associated with progression to severe dengue infection to prevent potentially fatal complications and to identify the determinants of severe complicated dengue.Methods:The study was conducted in a tertiary care hospitaldengue ward from September to November 2021 including confirmed dengue infected patients(positive NS1 antigen or antidengue-antibodies IgM).Secondary dengue infection was labelled by positive anti-dengue-antibodies IgG in active dengue infected patients.Detailed history,physical examination,laboratory and radiological parameters,hospital stay(days)and mortality percentages were noted.Patients were classified into three groups according to disease severity:dengue fever(DF),dengue hemorrhagic fever(DHF)and dengue shock syndrome(DSS).The predictors of complicated dengue infection were determined by regression analysis.Results:The most common symptom was fever(96.9%).Among 129 patients,62.8%had DF,31.0%had DHF and only 6.2%developed DSS.History of previous symptomatic dengue and positive anti-dengue-antibodies IgG were present in 100%DSS patients and nearly 75.0%DHF patients(P<0.05).The moratlity rate in patients with DSS,DHF and DF was 50.0%,2.5%and none respectively(P<0.05).Clinical parameters(body aches,bleeding,conjunctival hemorrhage,maculopapular rash,right hypochondrial tenderness,ascites,pleural effusion)and laboratory parameters(thrombocytopenia,raised alanine aminotransferase and secondary dengue infection)were determinants that complicate the dengue infection.Conclusions:Thrombocytopenia,raised alanine aminotransferase and secondary dengue infection are important laboratory parameters to complicate the disease process of dengue infection. | Ikram Waheed Samreen Khalid Zubia Jamil | 2022 | Asian Pacific Journal of Tropical Medicine2022，15，11： | 0 |
| 12 | Global trends in hepatitis C-related hepatocellular carcinoma mortality:A public database analysis(1999-2019)显示文摘BACKGROUND Hepatitis C is the leading cause of chronic liver disease worldwide and it significantly contributes to the burden of hepatocellular carcinoma(HCC).However,there are marked variations in the incidence and mortality rates of HCC across different geographical regions.With the advent of new widely available treatment modalities,such as direct-acting antivirals,it is becoming increasingly imperative to understand the temporal and geographical trends in HCC mortality associated with Hepatitis C.Furthermore,gender disparities in HCC mortality related to Hepatitis C are a crucial,yet underexplored aspect that adds to the disease's global impact.While some studies shed light on gender-specific trends,there is a lack of comprehensive data on global and regional mortality rates,particularly those highlighting gender disparities.This gap in knowledge hinders the development of targeted interventions and resource allocation strategies.DISCUSSION The results of our study show an overall decline in the mortality rates of patients with hepatitis C-related HCC over the last two decades.Notably,females exhibited a remarkable decrease in mortality compared to males.Regionally,East Asia and the Pacific displayed a significant decline in mortality,while Europe and Central Asia witnessed an upward trend.Latin America and the Caribbean also experienced an increase in mortality rates.However,no significant difference was observed in the Middle East and North Africa.North America exhibited a notable upward trend.South Asia and Sub-Saharan Africa significantly declined throughout the study period.This raises the hope of identifying areas for implementing more targeted resources.Despite some progress,multiple challenges remain in meeting the WHO 2030 goal of eliminating viral hepatitis[24]. | Hassam Ali Fnu Vikash Vishali Moond Fatima Khalid Abdur Rehman Jamil Dushyant Singh Dahiya Amir Humza Sohail Manesh Kumar Gangwani Pratik Patel Sanjaya K Satapathy | 2024 | World Journal of Virology2024，13，1： | 0 |
| 13 | Drought Tolerance in Mung Bean is Associated with the Genotypic Divergence, Regulation of Proline, Photosynthetic Pigment and Water Relation显示文摘Drought is one of the critical conditions for the growth and productivity of many crops including mung bean(Vigna radiata L.Wilczek).Screening of genotypes for variations is one of the suitable strategies for evaluating crop adaptability and global food security.In this context,the study investigated the physiological and biochemical responses of four drought tolerant(BARI Mung-8,BMX-08010-2,BMX-010015,BMX-08009-7),and four drought sensitive(BARI Mung-1,BARI Mung-3,BU Mung-4,BMX-05001)mung bean genotypes under wellwatered(WW)and water deficit(WD)conditions.The WW treatment maintained sufficient soil moisture(22%±0.5%,i.e.,30%deficit of available water)by regularly supplying water.Whereas,the WD treatment was maintained throughout the growing period,and water was applied when the wilting symptom appeared.The drought tolerant(DT)genotypes BARI Mung-8,BMX-08010-2,BMX-010015,BMX-08009-7 showed a high level of proline accumulation(2.52–5.99 mg g^(−1) FW),photosynthetic pigment(total chlorophyll 2.96–3.27 mg g^(−1) FW at flowering stage,and 1.62–2.38 mg g^(−1) FW at pod developing stage),plant water relation attributes including relative water content(RWC)(82%–84%),water retention capacity(WRC)(12–14)as well as lower water saturation deficit(WSD)(19%–23%),and water uptake capacity(WUC)(2.58–2.89)under WD condition,which provided consequently higher relative seed yield.These indicate that the tolerant genotypes gained better physiobiochemical attributes and adaptability in response to drought conditions.Furthermore,the genotype BMX-08010-2 showed superiority in terms of those physio-biochemical traits,susceptibility index(SSI)and stress tolerance index(STI)to other genotypes.Based on the physiological and biochemical responses,the BMX-08010-2 was found to be a suitable genotype for sustaining yield under drought stress,and subsequently,it could be recommended for crop improvement through hybridization programs.In addition,the identified traits can be used as markers to identify tolerant genotypes for drought-prone areas. | Mohammad Rafiqul Islam Mohd Mostofa Kamal Mohammad Faruk Hossain Jamil Hossain Mohammad Golam Azam Mst Masuma Akhter MKamrul Hasan Ibrahim Al-Ashkar Khalid FAlmutairi Ayman EL Sabagh Md Atikur Rahman Muhammad Aamir Iqbal Mohammad Sohidul Islam | 2023 | Phyton-International Journal of Experimental Botany2023，92，3： | 0 |
| 14 | 生物植入用碳纳米管增强混合功能梯度材料的力学性能(英文)显示文摘利用羟基磷灰石(HA)、不锈钢316L(SS316L)和碳纳米管(CNT)制备生物医学植入体用混合功能梯度材料(FGM)。加入SS316L和CNT增强功能梯度材料离散层的HA制成三种不同类型的功能梯度材料。第一种功能梯度材料加入10%~40%(质量分数)的SS316L强化微米HA,浓度梯度为10%。第二种功能梯度材料,在第一种功能梯度材料的基础上加入0.5%(质量分数)的功能化碳纳米管。第三种功能梯度材料在第二种功能梯度材料的基础上加入微米HA和纳米HA(1:1)的混合物。所有类型的功能梯度材料在相似的压缩参数和烧结参数下,进行单轴压缩实验,并采用无压烧结技术进行烧结。结果表明,加入碳纳米管和纳米晶体HA提高了功能梯度材料的致密度。碳纳米管增强的功能梯度材料的硬度和断裂韧性增加,但是微米和纳米晶体HA增强的功能梯度材料的硬度和断裂韧性的增加更明显。 | M.Asif HUSSAIN Adnan MAQBOOL F.Ahmad KHALID Nabi BAKHSH Ali HUSSAIN Jamil Ur RAHMAN Jong Kyu PARK Tae Gone PARK Lee Jae HYUN Myong Ho KIM | 2014 | Transactions of Nonferrous Metals Society of China2014，24，S1： | 0 |
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