|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Testing of biological aerated filter (BAF) media 显示文摘 | Kent T D Fitzpatrick C S B Williams S C | 1996 | Wat Sci Tech1996，34，34： | 2 |
| 4 | Meat tenderness and muscle growth: is there any relationship? 显示文摘 | Koohmaraie M Kent M P Shackelford S D Veiseth E Wheeler T L | 2002 | Meat Science2002，62，： | 1 |
| 5 | The mental health of UK Gulfwar veterans:phase 2 of a two phase cohort study显示文摘 | Ismail K Kent K Brugha T | 2002 | BMJ2002，325，7364： | 1 |
| 6 | Developing a Logistics Service Quality Scale显示文摘 | Mentzer J T Flint D J Kent J L | | 0，，01： | 1 |
| 7 | Testing of biological aerated filter (BAF) media显示文摘 | T D Kent S C Williams | 1996 | Water Science Technology1996，34，： | 1 |
| 8 | Modulation of CDK2-AP1 (p12(DOC-1))expression in human colorectal cancer显示文摘 | YUAN Z GABA A G KENT T S | 2005 | Oncogene2005，24，： | 1 |
| 9 | Interactions between terminally substituted amino acids in an aqueous and a non-aqueous environment显示文摘 | Lilley T H Milburn P J | 1985 | J Soln Chem1985，14，： | 1 |
| 10 | Image analysis and fractal geometry to characterize soil desiccation cracks 显示文摘 | Baer J U Kent T F Anderson S H | 2009 | Geoderma2009，154，1： | 1 |
| 11 | Minimally invasive resection of benign esophageal tumors 显示文摘 | Kent M D'Amato T Nordman C | 2007 | J Thorac Car Diovasc Surg2007，134，1： | 1 |
| 12 | Thoracoscopic ligation of the thoracic duct显示文摘 | Kent R B 3rd Pinson T W | 1993 | Surg Endosc1993，7，： | 1 |
| 13 | Differential expression of DOC-1 in microsatellite-unstable human colorectal cancer显示文摘 | YUAN Z SOTSKY KENT T WEBER T K | 2003 | Oncogene2003，22，40： | 1 |
| 14 | Structure - Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors显示文摘 | Zhi - Fu T Le W Kent D S | 2007 | J Med Chem2007，50，： | 1 |
| 15 | Brain oedema in focal ischaemia:molecular pathophysiology and theoretical implications显示文摘 | Simard J M Kent T A Chen M | 2007 | Lancet Neurol2007，6，3： | 1 |
| 16 | The Russell-Yasuda Kasai model: an asset liability model for a Japanese insurance company using multistage stochastic programming显示文摘 | Carino D R Kent T Myers D H | 1994 | Interfaces1994，24，1： | 1 |
| 17 | Testing of biological aerated filter (BAF) media显示文摘 | Kent T D Fitzpatrick C S B William S C | 1996 | Water Sci Technol1996，34，34： | 1 |
| 18 | High - resolution DNA melting analysis for simple and efficient molecular diagnostics 显示文摘 | REED G H KENT J O WITYWER C T | 2007 | Pharmacoengenomios2007，8，6： | 1 |
| 19 | Does melatonin modulate betaendorphin,corticosterone,and pain threshold?显示文摘 | Barrett T Kent S Voudouris N | 2000 | Life Sci2000，66，6： | 1 |
| 20 | A structured model for penicillin production on mixed substrates显示文摘 | PAUL G C SYDDALL M T KENT C A | 2001 | Biochemical Engineering Journal2001，7，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员