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69篇 您的检索式:作者名="Kendrew"
    题名 作者 年代 出处 被引量
1Patterns of in-hospital mortality and bleeding complications following PCI for very elderly patients: insights from the Dartmouth Dynamic Registry显示文摘BackgroundVery 老病人(年龄 85 年) 是人口的一个很快增加的片断。作为一个组,他们经历跟随经皮的冠的干预(一种总线标准) 的在里面医院死亡和流血复杂并发症的高率。然而,在流血和死亡在之间的关系老 unknown.MethodsRetrospective 评论在 Dartmouth-Hitchcock 从 2000 ~ 2015 在 17,378 连续一种总线标准过程上被执行医学中心。在索引一种总线标准承认期间流血的发生(流血要求的输送,存取地点 hematoma > 5 厘米, pseudoaneurysm,和 retroperitoneal 流血)? 并且在里面医院死亡为四个年龄组被报导(< 65 年, 65-74 年, 75-84 年,和 85 年) 。承受了谁的流血复杂并发症和那些的病人的死亡被计算, multivariate 分析为在里面医院被执行死亡。最后,知道流血的预言者在病人年龄之间被比较 < 85 年和年龄 17,378 个病人学习了的 85 years.ResultsOf,(5.9%) 1019 经历了流血,(2.1%) 369 死了在里面医院追随者一种总线标准。流血和在里面医院死亡的发生与增加年龄 monotonically 增加了(死亡:0.94% , 2.27% , 4.24% 和 4.58% ;流血:3.96% , 6.62% , 10.68% 和 13.99% 好久 < 65, 65-74, 75-84 和 85 年,分别地) 。除了病人年龄 85 年,在 multivariate 分析上,流血为所有年龄组与增加的死亡被联系[机会比率(95% CI ) :变老 < 65 年, 3.65 (1.99-6.74 ) ;年龄 65-74 年, 2.83 (1.62-4.94 ) ;年龄 75-84 年, 3.86 (2.56-5.82 ) ,年龄 85 年:1.39 (0.49-3.95 )] 有增加的 .ConclusionsBleeding 和死亡追随者一种总线标准增加变老。为老尽管有流血的高率,流血在里面医院死亡追随者一种总线标准不再是预兆的。Shawn X Li Hannah I Chaudry Jiyong Lee Theodore B Curran Vishesh Kumar Kendrew K Wong Bruce W Andrus James T DeVries 2018Journal of Geriatric Cardiology2018,15,2:6
2基于自参考的高精度红外点衍射干涉仪研制(英文)显示文摘介绍了一种结构简单紧凑、可用于高精度实时相位波前测量的红外点衍射干涉仪,采用类迈克耳孙的光学结构,并结合低通小孔滤波,同时使用窗口傅里叶变换的方法解调单幅离轴载波条纹。与传统波前测量技术相比,所提出的准共光路的光学系统结构有效地抑制了系统像差及外部环境干扰等对测量结果的影响,实现高精度和高分辨率的波前探测。实验结果表明,该方法能够实现高精度的相位测量,且其重复精度达到了纳米量级。杨朋千 Stefan Hippler Casey Deen Wolfgang Brandner Sarah Kendrew 缪洁 张艳丽 朱健强(指导) 2013中国激光2013,40,5:3
3ZD1839 ('IRESSA ') A selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI):inhibition of c-fos mRNA,an intermediate marker of EGFR activation,correlates with tumor growth inhibition显示文摘Woodburn JR Kendrew J Fennell M 2000Proceedings of the American Association for Cancer Research2000,,:1
4Modulation of polyketides synthase activity by accessory proteins during lovastatin biosynthesis 显示文摘Kenndy J Auclair K Kendrew S G 1999Science1999,284,:1
5Combination of the VEGF receptor tyrosine kinase inhibitor ZD6474 and vascular - targeting agent ZD6126 produces an enhanced anti - tumorre-sponse显示文摘Wedge SR Kendrew J Ogilvie D J 2002Proc Am Assoc Cancer Res2002,43,:1
6AZD2171:A highly potent,orally bioavailable,vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer显示文摘Wedge SR Kendrew J Hennequin LF 0,,10:1
7Biosynthesis of the immunosuppressants FK506,FK520,and rapamycininvolves a previously undescribed family of enzymes acting on chorismate显示文摘Andexer J N Kendrew S G Alam M N 0,,:1
8Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate显示文摘Andexer JN Kendrew SG NureAlam M 2011Proceedings of the National Academy of Sciences of the United States of America2011,108,12:1
9AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer显示文摘Wedge SR Kendrew J Hennequin LF 2005Cancer Res2005,65,10:1
10Modulation ofpolyketide synthase activity accessory proteins during lovastatinbiosythesis显示文摘KENNEDY J AUCLAIR K KENDREW SG 1999Science1999,284,5418:1
11Mondulation of polyketides synthase activity by accessory proteins during lova- tion biosythesis显示文摘Kenndy J Auclair K Kendrew S G 1999Science1999,284,:1
12Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis显示文摘Miotla J Maciewicz R Kendrew J 2000Lab Invest2000,80,8:1
13Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: purification and characterization of the recombinant enzyme显示文摘Kendrew SG Hopwood DA Marsh EN 1997Journal of Bacteriology1997,179,13:1
14Modulation of polyketides synthase activity by accessory proteins during lovastatin biosynthesis 显示文摘KENNEDY J AUCLAIR K KENDREW S G 1999Science1999,284,5418:1
15Treatment with soluble VEGF receptor reduces disease severity in murine collagen-induced arthritis显示文摘Miotla J Maciewicz R Kendrew J 2000Lab Invest2000,80,10:1
16The structure of globular proteins显示文摘KENDREW J C 1962Comp Biochem Physiol1962,4,:1
17AZD2127:A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer显示文摘Wedge SR Kendrew J Hennequin LF 2005Cancer Res2005,65,:1
18显示文摘Miotla J Maciewicz R Kendrew J 2000Lab Invest2000,80,8:1
19Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis显示文摘KENNEDY J AUCLAIR K KENDREW S G 1999Science1999,284,5418:1
20Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis 显示文摘Joathan Kennedy Karine Auclair Steven G Kendrew 1999Microbiology1999,,284:1
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