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| 1 | Percutaneous liver biopsy complicated by hemobilia-associated acute cholecystitis显示文摘肝活体检视通常被认为一只保险箱和高度有用的过程。它经常在众多的肝混乱为诊断和后续在一个门诊病人背景被执行。自从它在第 19 世纪,宽广经验,新成像技术和专辑的结束的介绍,针显著地减少了与肝活体检视联系的复杂并发症的率。肝的经皮的活体检视的已知的复杂并发症包括血腹膜,代替胶囊的血肿,低血压,气胸和败血。另外的 intra 腹的复杂并发症是不太普通的。胆道出血由于 arterio 胆汁的管管被描述了,它临床上仅仅很少被表示了为胆汁或胰腺炎。我们报导开发了在经皮的肝活体检视以后的 12 天在一个门诊病人背景执行了的严重尖锐胆汁的十五个 57 岁的男孩的一个案例。病原学清楚地被表明联系 hemobilia,并且临床的功课要求了 laparoscopic 胆囊炎的表演。起作用的柱子路线是平静的,病人回家被解除。经皮的肝活体检视是一个安全、通常执行的过程。然而,严重复杂并发症能偶尔发生。当处理这些稀罕事件时,医药、外科的选择应该被评估。 | Yair Edden Hugo St Hilaire Keith Benkov Michael T Harris | 2006 | World Journal of Gastroenterology2006，12，27： | 2 |
| 2 | Evaluation and treatment of internal impingement of the shoulder in overhead athletes显示文摘One of the most common pathologic processes seen in overhead throwing athletes is posterior shoulderpain resulting from internal impingement. 'Internal impingement' is a term used to describe a constellation of symptoms which result from the greater tuberosity of the humerus and the articular surface of the rotator cuff abutting the posterosuperior glenoid when the shoulder is in an abducted and externally rotated position. The pathophysiology in symptomatic internal impingement is multifactorial,involving physiologic shoulder remodeling,posterior capsular contracture,and scapular dyskinesis. Throwers with internal impingement may complain of shoulder stiffness or the need for a prolonged warm-up,decline in performance,or posterior shoulder pain. On physical examination,patients will demonstrate limited internal rotation and posterior shoulder pain with a posterior impingement test. Common imaging findings include the classic 'Bennett lesion' on radiographs,as well as articular-sided partial rotator cuff tears and concomitant SLAP lesions. Mainstays of treatment include intense non-operative management focusing on rest and stretching protocols focusing on the posterior capsule. Operative management is variable depending on the exact pathology,but largely consists of rotator cuff debridement. Outcomes of operative treatment have been mixed,therefore intense non-operative treatment should remain the focus of treatment. | Keith T Corpus Christopher L Camp David M Dines David W Altchek Joshua S Dines | 2016 | World Journal of Orthopedics2016，7，12： | 2 |
| 3 | Effects of Ionic Strength, Temperature, and pH on Degradation of Selected Antibiotics显示文摘 | Loftin Keith A Adams Craig D Meyer Michael T Surampalli Rao | 2008 | Journal of Environmental Quality2008，，2： | 2 |
| 4 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 5 | Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘 | Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne | 2010 | Journal of the American College of Cardiology2010，，3： | 2 |
| 6 | Analytical methods for detection of selected estrogenic compounds in aqueous mixtures 显示文摘 | Snyder S A Keith T L Verbrugge D A | 1999 | Environ Sci Technol1999，33，16： | 2 |
| 7 | RolEnact:role-basedenactable models of business processes显示文摘 | KEITH T PETER H ROBERT J | 1998 | Information and Soft-ware Technology1998，40，3： | 1 |
| 8 | The three-stratum theory of cognitive abilities:Test of the structure of intelligence across the life span显示文摘 | Keith T Z Wolfle L.M | | 0，，： | 1 |
| 9 | Randomized controlled trial with low-dose spiral CT for lung cancer screening :feasibility study and preliminary results显示文摘 | Garg K Keith RL Byers T | 2002 | Radiology2002，225，2： | 1 |
| 10 | Dynamic model- ing of a dual clearance squeeze film damper:Part I test rigand dynamic model with one damper显示文摘 | Moraru L Keith T G Jr Dimofte F | 2003 | Tribology Trans- actions2003，46，2： | 1 |
| 11 | PIK-Related Kinases: DNA repair, recombination, and cell cycle checkpoint显示文摘 | Keith C T Schreiber S L | 1995 | Science1995，270，1： | 1 |
| 12 | Bioconcentration of nonyiphenol in fathead minnows ( pimephales promelas) 显示文摘 | SNYDER S A KEITH T L PIERENS S L | 2001 | Chemosphere2001，44，8： | 1 |
| 13 | Control of p70 S6 kinase by kinase activity of FRAP in vivo显示文摘 | Brown E J Beal P A Keith C T | 1995 | Nature1995，377，6548： | 1 |
| 14 | Biosensor technology: technology push versus market pull显示文摘 | JOHN H T L KEITH B M JEREMY D G | 2008 | Biotechn Adv2008，26，5： | 1 |
| 15 | Dynamic model- ing of a dual clearance squeeze film damper: Part II 显示文摘 | Moraru L Keith T G Jr Dimofte F | 2006 | Tribology Transactions2006，49，4： | 1 |
| 16 | Estimating the environmental costs of soil erosion at multiple scales in Kenya using emergy synthesis 显示文摘 | Matthew J Cohen Mark T Brown Keith D Shepherd | 2006 | Agriculture Ecosystems and Environment2006，114，2： | 1 |
| 17 | 成人2型糖尿病不同筛查及预防策略成本效益分析显示文摘目的 比较针对2型糖尿病预防及治疗的4种筛查策略及随后予以的干预措施:(a)筛查2型糖尿病患者使其能接受早期检查及治疗,(b)筛查2型糖尿病和糖耐量受损患者,对糖耐量受损的人群予以生活方式干预以延缓或预防糖尿病的发生,(c)同(b)但予以药物干预措施,(d)不筛查。
设计 成本效益决策分析建立在对概率的发展和评估基础上,是从筛查到死亡的综合性经济决策分析模型。
研究对象 一组假设人群,筛查时年龄45岁,高于平均糖尿病风险水平。
数据来源 电子书目数据库收录的已发表的临床试验和流行病学研究;补充数据分别来自英国和威尔士健康统计署、风险筛查(STAR)研究和ADDITION研究的Leicester部分。
方法 建立一种决策树/Markov混合模型,以模拟每一种筛查策略的长期效用,包括临床和成本效益终点。该模型假设水平跨度为50年时间,其成本效益折损率为3.5%。采用敏感度分析以验证模型假设及确定哪种模型数据输入对结果的影响最大。
结果 与不筛查策略比较,筛查2型糖尿病、筛查糖尿病和糖耐量受损并予以生活方式干预、筛查糖尿病和糖耐量受损并予以药物干预治疗3种策略,每获得一个质量调整生命年(QALY)估计所需成本分别为(每年成本效益贴现率为3.5%)14150英镑(17560欧元;27860美元)、6242英镑和7023英镑。在支付意愿阈值为20000英镑时,各主动筛查策略通过干预产生的成本效益概率分别为49%,93%和85%。
结论 对年龄45岁、高于平均风险水平的人群进行2型糖尿病和糖耐量受损的筛查,并对糖耐量受损人群予以适当的干预似乎具有很好的成本效益。单独筛查糖尿病而不对糖耐量受损人群予以干预的策略具有的成本效益仍不确定,需要进一步研究确定早期检测糖尿病的作用。 | Clare L Gillies Paul C Lambert Keith R Abrams Alex J Sutton Nicola J Cooper Ron T Hsu Melanie J Davies Kamlesh Khunti 张晓梅(译) 纪立农(校) | 2008 | 英国医学杂志中文版2008，11，5： | 1 |
| 18 | Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human of ear显示文摘 | Yilin Cao Joseph P Vacanti Keith T Paige | 1997 | Plastic and Reconstructive Surgery1997，100，： | 1 |
| 19 | Angiographic Versus Functional Severity of Coronary Artery Stenoses in the FAME Study显示文摘 | Pim A.L. Tonino William F. Fearon Bernard De Bruyne Keith G. Oldroyd Massoud A. Leesar Peter N. Ver Lee Philip A. MacCarthy Marcel van’t Veer Nico H.J. Pijls | 2010 | Journal of the American College of Cardiology2010，，25： | 1 |
| 20 | Multi-target therapeutics: when the whole is greater than the sum of the parts显示文摘 | ZIMMERMANN G R LEHAR J KEITH C T | 2007 | Drug Discov Today2007，12，12： | 1 |
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