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| 1 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016，22，20： | 5 |
| 2 | Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats 显示文摘 | JIANG Y M YANG Y K KIMBER L | 2002 | J Appl Physiol2002，92，1： | 1 |
| 3 | Effects of biochar form slow pyrolysis of parper waste on agromic performance and soil fertility 显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant and soil2010，327，12： | 1 |
| 4 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant and Soil2010，327，： | 1 |
| 5 | Early stages of implantation as revealed by an in vitro model显示文摘 | SINGH H NARDO L KIMBER S J | 2010 | Reproduction22010，139，5： | 1 |
| 6 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | ZWIETEN L VAN KIMBER S MORRIS S | 2010 | Plant and Soil2010，327，12： | 1 |
| 7 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility 显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant and Soil2010，327，： | 1 |
| 8 | Influence of biochars on flux of N20 and CO2 from ferrosol显示文摘 | Zwieten L Kimber S Morris S | 2010 | Australian Journal of Soil Research2010，48，7： | 1 |
| 9 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Zwieten L Van Kimber S Morris S | 2010 | Plant and Soil2010，327，12： | 1 |
| 10 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant and Soil2010，327，12： | 1 |
| 11 | Effects of biochar from slow pyrolysis of papermill waste on ag- ronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant and Soil2010，327，1： | 1 |
| 12 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Van Z L Kimber S Morris S | 2010 | Plant and Soil2010，327，12： | 1 |
| 13 | Effects of biochar from slow pyroly- sis of papermill waste on agronomic performance and soil fertility 显示文摘 | Van Z L Kimber S Morris S | 2009 | Plant and Soil2009，327，12： | 1 |
| 14 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | | 0，，： | 1 |
| 15 | Effects of biochar from slow pyrolysis of papermill wasteon agronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant Soil2010，327，12： | 1 |
| 16 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Zwieten L V Kimber S Morris S | 2010 | Plant and Soil2010，327，1： | 1 |
| 17 | Etibct oi blochar lmm slow pymlysisi of papermill waste on agronomic performance and soil fertility 显示文摘 | ZWIETEN V L KIMBER S MORRIS S | 2010 | Plant and Soil2010，327，12： | 1 |
| 18 | Effects ofbiochar from slow pyrolysis of papermill waste onagronomic performance and soil fertility显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant Soil2010，327，12： | 1 |
| 19 | Effects of biochar from slow pyrolysis of papermill waste on agronomic performance and soil fertility显示文摘 | Zwieten L V Kimber S Morris S | 2010 | Plant and Soil2010，327，： | 1 |
| 20 | Effects of biochar from slow pyrolysis of papermill wasteon agronomic performance and soil fertility 显示文摘 | Van Zwieten L Kimber S Morris S | 2010 | Plant Soil2010，327，12： | 1 |
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