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| 1 | The strigolactone receptor D14 targets SMAX1 for degradation in response to GR24 treatment and osmotic stress显示文摘The effects of the phytohormone strigolactone(SL)and smoke-derived karrikins(KARs)on plants are generally distinct,despite the fact that they are perceived through very similar mechanisms.The homologous receptors DWARF14(D14)and KARRIKIN-INSENSITIVE2(KAI2),together with the F-box protein MORE AXILLARY GROWTH2(MAX2),mediate SL and KAR responses,respectively,by targeting different SMAX1-LIKE(SMXL)family proteins for degradation.These mechanisms are putatively well-insulated,with D14-MAX2 targeting SMXL6,SMXL7,and SMXL8 and KAI2-MAX2 targeting SMAX1 and SMXL2 in Arabidopsis thaliana.Recent evidence challenges this model.We investigated whether D14 can target SMAX1 and whether this occurs naturally.Genetic analysis indicates that the SL analog GR24 promotes D14-SMAX1 crosstalk.Although D14 shows weaker interactions with SMAX1 than with SMXL2 or SMXL7,D14 mediates GR24-induced degradation of SMAX1 in plants.Osmotic stress triggers SMAX1 degradation,which is protective,through SL biosynthesis and signaling genes.Thus,D14-SMAX1 crosstalk may be beneficial and not simply a vestige of the evolution of the SL pathway. | Qingtian Li Elena Sánchez Martín-Fontecha Aashima Khosla Alexandra R.F.White Sunhyun Chang Pilar Cubas David C.Nelson | 2022 | Plant Communications2022，3，2： | 5 |
| 2 | Models for optimal lead time reduction 显示文摘 | Hill A V Khosla I S | 1992 | Production and Operations Management1992，1，2： | 1 |
| 3 | Osteoporosis:now and the future 显示文摘 | Rachner TD Khosla S Hofbauer LC | 2011 | Lancet2011，377，9773： | 1 |
| 4 | Hyperuricemia induces endothelial dysfunction显示文摘 | Khosla UM Zharikov S Finch JL | 2005 | Kidney Int2005，67，5： | 1 |
| 5 | Hyperuricemia induces en- dothelial dysfunction 显示文摘 | Khosla UM Zharikov S Finch JL | 2005 | Kidney Int2005，67，5： | 1 |
| 6 | Role of RANK ligand in mediating increased bone resorption in early postmenopausal women显示文摘 | Eghbali-Fatourechi G Khosla S Sanyal A Boyle WJ Lacey DL Riggs BL | | 0，，： | 1 |
| 7 | The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption显示文摘 | Hofbauer L.C Khosla S Dunstan C.R | | 0，，： | 1 |
| 8 | Osteoporosis: now and thefuture显示文摘 | Rachner TD Khosla S Hot'bauer LC | 2011 | Lancet2011，377，9773： | 1 |
| 9 | Osteoporosis:now and the future显示文摘 | Rachner TD Khosla S Hofbauer LC | 2011 | Lancet2011，377，9773： | 1 |
| 10 | Update on estrogens and the skeleton显示文摘 | Khosla S | 2010 | J ClinEndocrinol Metab2010，95，8： | 1 |
| 11 | Hyperuricemia induces endothelial dysfunction显示文摘 | Khosla UM Zharikov S Finch JL | 2005 | Kidney Int2005，67，5： | 1 |
| 12 | Minireview: The OPG/RANKL/RANK system 显示文摘 | Khosla S | 2001 | Endocrinology2001，142，12： | 1 |
| 13 | The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption显示文摘 | Hofbauer L C Khosla S Dunstan C R | 2000 | J Bone Miner Res2000，，15： | 1 |
| 14 | Clinical review144:Estrogen and the male skeleton显示文摘 | Khosla S Melton L J Riggs B L | 2002 | J Clin Endocrinol Metab2002，87，4： | 1 |
| 15 | Osteoporosis:now and the future显示文摘 | Rachner TD Khosla S Hofbauer LC | 2011 | Lancet2011，377，9773： | 1 |
| 16 | Male osteoporosis 显示文摘 | Drake M T Khosla S | 2012 | Endocrinol Metab Clin North Am2012，41，3： | 1 |
| 17 | Osteoporosis update from the 2010 santa fe bone symposium显示文摘 | Ewiecki EM Bilezikian JP Khosla S | 2011 | J Clin Densitom2011，14，： | 1 |
| 18 | keptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes显示文摘 | Thomas T Gori F Khosla S | 1999 | Endocrinology1999，140，： | 1 |
| 19 | The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption 显示文摘 | Hofbauer LC Khosla S Dunstan CR | 2000 | J Bone Miner Res2000，15，： | 1 |
| 20 | Minireview: the OPG/HANKL/HANK system 显示文摘 | Khosla S | 2001 | En-docrinology2001，142，： | 1 |
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