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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Ankle Fractures in the Elderly: What You Get Depends on Where You Live and Who You See显示文摘 | Kenneth J Koval Jon Lurie Weiping Zhou Michael B Sparks Robert V Cantu Scott M Sporer James Weinstein | 2005 | Journal of Orthopaedic Trauma2005，，9： | 2 |
| 3 | Amyloid β-peptide impairs ion-motive ATPase activities:evidence for a role in loss of neuronal Ca^2+ Homeostasis and cell death显示文摘 | Robert J M Kenneth H Allan B | 1995 | J Neurosci1995，15，9： | 1 |
| 4 | Numerical Modeling of Concrete Confined by Fiber-Reinforced Composites显示文摘 | Malvar L J Kenneth B M John E C | 2004 | Journal of Composites for Construction2004，8，4： | 1 |
| 5 | Discounts and premium on closed-end mutual fund: a study in valuation 显示文摘 | Kenneth J B | 1973 | Journal of Finance1973，28，2： | 1 |
| 6 | The prognostic value of histology in the assessment of patients with Budd–Chiari syndrome显示文摘 | Thjon J Tang Kenneth P Batts Piet C de Groen Bart van Hoek Elizabeth B Haagsma Wim C.J Hop Harry L.A Janssen | 2001 | Journal of Hepatology2001，，3： | 1 |
| 7 | The Political Economy of Benefits and Costs : A Neoclassical Approach to Distributive Politics 显示文摘 | Weingast B Kenneth S Christopher J | 1981 | Journal of Political Economy1981，89，： | 1 |
| 8 | High-resolution image reconstruction from a sequence of rotated and translated frames and its application to an infrared imaging system显示文摘 | Russell C H Kenneth J B John G B | 1998 | Optical Engineering1998，37，1： | 1 |
| 9 | Kinetics and mechanisms of thermal decomposition of nitzoazomatic explosives显示文摘 | Brill B Kenneth J James | 1993 | Chemistry Review1993，93，： | 1 |
| 10 | Modeling thermally thick pyrolysis of wood 显示文摘 | KENNETH M B KENNETH W R RUTLAND C J | 2002 | Biomass and Bioenergy2002，22，： | 1 |
| 11 | Evolutionary relationships, interisland biogeography, and molecular evolution in the Hawaiian violets (Viola: Violaceae) 显示文摘 | Christopher H J Kenneth J S Harvey E B J | 2009 | Am JBot2009，96，： | 1 |
| 12 | The utilization of risk assessments in tactical command decisions 显示文摘 | WARREN W J KENNETH R S G BRUCE B | 2002 | Sei Total Environ2002，288，： | 1 |
| 13 | Rooting characteristics and associated drought resistance of zoysiagrass显示文摘 | Kenneth B M Engelke M C Morton S J | 1995 | Agron J1995，87，： | 1 |
| 14 | Freezing thawing effects on storey metabolic enzymes in wood frog organ's显示文摘 | Kra J cawan and Kenneth B | 2001 | Cryobiology2001，43，： | 1 |
| 15 | Benefits associated with supplier integration into new product development under conditions of technology uncertainty 显示文摘 | GARY L R ROBERT B H KENNETH J P | 2002 | Business Research2002，，55： | 1 |
| 16 | Coherence factor enhance-ment of through-wall radar images显示文摘 | ROBERT J B KENNETH E B | 2010 | IEEE Antennas and Wireless Propagation Letters2010，9，： | 1 |
| 17 | A multispecialty approach to the diagnosis and management of pancreatic cancer显示文摘 | Robert H Hawes Qinghua Xiong Irving Waxman Kenneth J Chang Douglas B Evans James L Abbruzzese | 2000 | The American Journal of Gastroenterology2000，，1： | 1 |
| 18 | Knowledge Sharing in Interorganizational Product Development Teams: The Effect of Formal and Informal Socializa?tion Mechanisms 显示文摘 | Benn Lawson Kenneth J Petersen Paul D Cousins Handfield R B | 2009 | Journal of Product Innovation Manage?ment2009，26，2： | 1 |
| 19 | Creating supply chain relational capital: The im- pact of formal and informal socialization processes显示文摘 | Paul D Cousins Robert B Handfield Benn Lawson Kenneth J Petersen | 2006 | Jour- nal of Operations Management2006，24，： | 1 |
| 20 | Testing and improving evapotranspiration and soil water balance of the DSSAT crop models显示文摘 | Federico S Kenneth J B Bostick W M | 2004 | Agronomy Journal2004，96，： | 1 |
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