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| 1 | Current concept in dysplastic hip arthroplasty: Techniques for acetabular and femoral reconstruction显示文摘Adult patients with developmental dysplasia of the hip develop secondary osteoarthritis and eventually end up with total hip arthroplasty(THA) at younger age. Because of altered anatomy of dysplastic hips, THA in these patients represents technically demanding procedure. Distorted anatomy of the acetabulum and proximal femur together with conjoined leg length discrepancy present major challenges during performing THA in patients with developmental dysplasia of the hip. In addition, most patients are at younger age, therefore, soft tissue balance is of great importance(especially the need to preserve the continuity of abductors) to maximise postoperative functional result. In this paper we present a variety of surgical techniques availablefor THA in dysplastic hips, their advantages and disadvantages. For acetabular reconstruction following techniques are described: Standard metal augments(prefabricated), Custom made acetabular augments(3D printing), Roof reconstruction with vascularized fibula, Roof reconstruction with pedicled iliac graft, Roof reconstruction with autologous bone graft, Roof reconstruction with homologous bone graft, Roof reconstruction with auto/homologous spongious bone, Reinforcement ring with the hook in combination with autologous graft augmentation, Cranial positioning of the acetabulum, Medial protrusion technique(cotyloplasty) with chisel, Medial protrusion technique(cotyloplasty) with reaming, Cotyloplasty without spongioplasty. For femoral reconstruction following techniques were described: Distraction with external fixator, Femoral shortening through a modified lateral approach, Transtrochanteric osteotomies, Paavilainen osteotomy, Lesser trochanter osteotomy, Double-chevron osteotomy, Subtrochanteric osteotomies, Diaphyseal osteotomies, Distal femoral osteotomies. At the end we present author's treatment method of choice: for acetabulum we perform cotyloplasty leaving only paper-thin medial wall, which we break during acetabular cup impacting. For femoral side first we peel of all rotators and posterior part of gluteus medius and vastus lateralis from greater trochanter on the very thin flake of bone. This method allows us to adequately shorten proximal femoral stump, with possibility of additional resection of proximal femur. Furthermore, several advantages and disadvantages of this procedure are also discussed. | Goran Bicanic Katarina Barbaric Ivan Bohacek Ana Aljinovic Domagoj Delimar | 2014 | World Journal of Orthopedics2014，5，4： | 27 |
| 2 | Critical minimum temperature limits xylogenesis and maintains treelines on the southeastern Tibetan Plateau显示文摘Physiological and ecological mechanisms that define treelines are still debated.It has been suggested that the absence of trees above the treeline is caused by low temperatures that limit growth.Thus,we hypothesized that there is a critical minimum temperature(CTmin) preventing xylogenesis at treeline.We tested this hypothesis by examining weekly xylogenesis across three and four growing seasons in two natural Smith fir(Abies georgei var.smithii) treeline sites on the southeastern Tibetan Plateau.Despite differences in the timing of cell differentiation among years,minimum air temperature was the dominant climatic variable associated with xylem growth;the critical minimum temperature(CTmin) for the onset and end of xylogenesis occurred at 0.7 ± 0.4 °C.A process-based modelling chronology of tree-ring formation using this CTminwas consistent with actual tree-ring data.This extremely low CTminpermits Smith fir growing at treeline to complete annual xylem production and maturation and provides both support and a mechanism for treeline formation. | Xiaoxia Li Eryuan Liang Jozica Gricar Sergio Rossi Katarina Cufar Aaron M. Ellison | 2017 | Science Bulletin2017，62，11： | 17 |
| 3 | Circulating tumor cells in pancreatic cancer patients:Enrichment and cultivation显示文摘AIM:To investigate the feasibility of separation and cultivation of circulating tumor cells(CTCs)in pancreatic cancer(Pa C)using a filtration device.METHODS:In total,24 Pa C patients who were candidates for surgical treatment were enrolled into the study.Peripheral blood samples were collected before an indicated surgery.For each patient,approximately8 m L of venous blood was drawn from the antecubitalveins.A new size-based separation Meta Cell?technology was used for enrichment and cultivation of CTCs in vitro.(Separated CTCs were cultured on a membrane in FBS enriched RPMI media and observed by inverted microscope.The cultured cells were analyzed by means of histochemistry and immunohistochemistry using the specific antibodies to identify the cell origin.RESULTS:CTCs were detected in 16 patients(66.7%)of the 24 evaluable patients.The CTC positivity did not reflect the disease stage,tumor size,or lymph node involvement.The same percentage of CTC positivity was observed in the metastatic and non-metastatic patients(66.7%vs 66.7%).We report a successful isolation of CTCs in Pa C patients capturing proliferating cells.The cells were captured by a capillary action driven size-based filtration approach that enabled cells cultures from the viable CTCs to be unaffected by any antibodies or lysing solutions.The captured cancer cells displayed plasticity which enabled some cells to invade the separating membrane.Further,the cancer cells in the'bottom fraction',may represent a more invasive CTC-fraction.The CTCs were cultured in vitro for further downstream applications.CONCLUSION:The presented size-based filtration method enables culture of CTCs in vitro for possible downstream applications. | Vladimir Bobek Robert Gurlich Petra Eliasova Katarina Kolostova | 2014 | World Journal of Gastroenterology2014，20，45： | 15 |
| 4 | Exchange flux of total gaseous mercury between air and natural water surfaces in summer season显示文摘The exchanges of mercury between surface and air are of significance in the biogeochemical cycling of Hg in the environment, but there are still few reliable data on air/surface exchange in aquatic systems. Field measurement campaigns over seawater surface at Kristineberg Marine Research Station (KMRS) and over Hovg?rds?n River surface at Knobesholm in southwestern Sweden were conducted to measure mercury flux using a dynamic flux chamber technique coupled with automatic mercury vapor-phase analyzers. Both sites show net emissions during summer time. Mercury fluxes measured over both river and seawater surfaces exhibit a consistently diurnal pattern with maximum fluxes during the daytime period and minimum fluxes during the nighttime period. At freshwater site, mercury flux is strongly correlated with the intensity of net solar radiation, and negatively correlated with relative humidity. A typical exponential relationship between mercury flux and water temperature was observed at freshwater measurement site. At seawater site, a strong correlation between mercury flux and intensity of solar radiation was obtained. The driving force of mercury emission from water surface to air is the super-saturation of dissolved gaseous mercury in aqueous phase. | 冯新斌 Jonas Sommar Katarina Grdfeldt OliverLindqvist | 2002 | Science China Earth Sciences2002，45，3： | 10 |
| 5 | 高温胁迫下不同热敏感性小麦光化学活性和能量分配差异显示文摘利用叶绿素荧光技术,研究高温胁迫下不同热敏感性小麦品种光化学活性和能量分配的差异。结果表明:在37.5℃以上的高温胁迫下,与热敏感的小麦品种‘Torysa’相比,耐热品种‘Ilona’通过保持高的PSII最大光化学效率(φPo)、捕获的能量向电子传递链传递的效率(ψo)以及用于电子传递的量子产额(φEo)使更多的能量被反应中心捕获并进入电子传递链,而热敏感品种‘Torysa’中较高的用于热耗散的量子比率(φDo)表明其更多的能量用于热耗散,从而使得‘Ilona’中光化学反应可以利用的能量多于‘Tor ysa’。与此同时,‘Ilona’还有相对更多的PSI参与环式电子传递,耗散多余的能量,从而减少活性氧的产生。因而在高温胁迫下,‘Ilona’能够维持较高的光化学效率,降低光抑制,具有更好的耐热性。 | 张会玲 Marian Brestic Katarina Olsovska 李刚 孟庆伟 杨兴洪 | 2015 | 植物生理学报2015，51，7： | 10 |
| 6 | Axonal regeneration after spinal cord injury in zebrafish and mammals: differences, similarities, translation显示文摘Spinal cord injury (SCI) in mammals results in functional deficits that are mostly permanent due in part to the inability of severed axons to regenerate. Several types of growth-inhibitory molecules expressed at the injury site contribute to this regeneration failure. The responses of axons to these inhibitors vary greatly within and between organisms, reflecting axons' characteristic intrinsic propensity for regeneration. In the zebrafish (Danio rerio) many but not all axons exhibit successful regeneration after SCi. This review presents and compares the intrinsic and extrinsic determinants of axonal regeneration in the injured spinal cord in mammals and zebrafish. A better understanding of the molecules and molecular pathways underlying the remarkable individualism among neurons in mature zebrafish may support the development of therapies for SCI and their translation to the clinic. | Katarina Vajn Jeffery A Plunkett Alexis Tapanes-Castillo Martin oudega | 2013 | Neuroscience Bulletin2013，29，4： | 9 |
| 7 | Galectin-3 possible involvement in antipsychotic-induced metabolic changes of schizophrenia:A minireview显示文摘Recently,specific immunometabolic profiles have been postulated in patients with schizophrenia,even before full-blown disease and independent of antipsychotic treatment.Proteomic profiling studies offer a promising potential for elucidating the cellular and molecular pathways that may be involved in the onset and progression of schizophrenia symptoms,and co-occurrent metabolic changes.In view of all this,we were intrigued to explore galectin-3(Gal-3)as a glycan,and in our previous study,we measured its elevated levels in remission of schizophrenia.The finding may be a consequence of antipsychotic treatment and may have an impact on the onset of inflammation,the development of obesity,and the presumed cognitive changes in schizophrenia.In the animal study,it was shown that downregulation of Gal-3 was beneficial in insulin regulation of obesity and cognitive preservation.Strategies involving plasma exchange are discussed in this review,particularly in the context of Gal-3 elimination. | Milica M Borovcanin Katarina Vesic Milena Jovanovic Natasa R Mijailovic | 2021 | World Journal of Diabetes2021，12，10： | 4 |
| 8 | Postoperative visual performance with a bifocal and trifocal diffractive intraocular lens during a 1-year follow-up显示文摘AIM:To evaluate and compare the clinical outcomes with a diffractive bifocal and trifocal intraocular lens(IOL) during a 12-month follow-up.METHODS:Prospective comparative study including 75 eyes of 38 patients(44-70 y) undergoing uneventful cataract surgery.Each patient was randomly assigned to one type of IOL,bifocal(35 eyes) or trifocal(40 eyes).Visual,refractive,and contrast sensitivity changes were evaluated in a 12-month follow-up.The binocular defocus curve was also measured at 12 mo postoperatively.RESULTS:No statistically significant differences between groups were found in postoperative uncorrected and corrected distance visual acuities(P≥0.276).Postoperative corrected near visual acuity(33 cm) was significantly better in the trifocal group during all follow-up(P≤0.004) as well as 6-month uncorrected near(P=0.008) and distancecorrected near visual acuities(P=0.016)(33/40 cm).Significantly better uncorrected intermediate and distance corrected-intermediate visual acuity were found during all follow-up in the trifocal group(P<0.001),which was consistent with differences among groups in binocular defocus curve.Differences among groups in contrast sensitivity were minimal,being only significant at 6 months for some low to medium spatial frequencies(P≤0.006).CONCLUSION:Bifocal and trifocal diffractive IOLs are able to provide an effective visual restoration which is maintained during a 12-month follow-up,with a clear benefit of the trifocal IOL for the intermediate vision. | Peter Mojzis Lucia Kukuckova Katarina Majerova Peter Ziak David P.Pi?ero | 2017 | International Journal of Ophthalmology(English edition)2017，10，10： | 3 |
| 9 | Transition after pediatric liver transplantation-Perceptions of adults, adolescents and parents显示文摘AIM To develop a locally adapted, patient-focused transitionprogram, we evaluated the perceptions of adult and adolescent patients and parents regarding transitionprograms and transfer.METHODS We evaluated these perceptions by analyzing the responses of pre-transfer adolescents(n = 57), their parents(n = 57) and post-transfer adults(n = 138) from a cohort of pediatric-liver-transplant-patients using a self-designed questionnaire. Furthermore, we compared a responder group with a non-responder group as well as the provided answers with baseline characteristics and clinical outcomes to exclude selection bias, characterize high-risk patients for nonadherence and test for gender differences. Included in our study were all pre-transfer liver transplant and combined liver-kidney transplant recipients aged 11-19 currently under our care and their parents, as well as all post-transfer liver transplant and combined liverkidney transplant recipients aged ≥ 17 years who had received a liver transplant and were treated at our center during childhood.RESULTS Fifty-seven(24 female) pre-transfer patients who received a transplant in the previous 8-186 mo(mean 93.9 mo, median 92 mo, SD 53.8 mo) and 138(57 female) post-transfer patients who received a transplant in the preceding 2-29 years(mean 15.6 years, median 17, SD 6.90) met the inclusion criteria. A total of 67% of pre-transfer patients(71% of female; 64% of male; P = 0.78) and their parents replied. Additionally, 54% of post-transfer patients(26% of female; 48% of male; P = 0.01) replied. No differences in clinical outcomes were observed between the responder and non-responder groups, and responses did not differ significantly based on clinical complication rates, although they did differ based on gender and the location of medical follow-up after transfer. Adolescents were generally ambivalent toward transition programs. However, adults strongly supported transition programs. CONCLUSION Transition programs need to be developed in close collaboration with adolescents. The best clinical practices regarding transition should respect local circumstances, gender and the location of post-transfer medical follow-up. | Norman Junge Katarina Migal Imeke Goldschmidt Ulrich Baumann | 2017 | World Journal of Gastroenterology2017，23，13： | 2 |
| 10 | Pentadecapeptide BPC 157 resolves suprahepatic occlusion of the inferior caval vein, Budd-Chiari syndrome model in ratsPentadecapeptide BPC 157 resolves suprahepatic occlusion of the inferior caval vein, Budd-Chiari syndrome model in rats显示文摘BACKGROUND Recently,as a possible therapy resolving solution,pentadecapeptide BPC 157 therapy,has been used in alleviating various vascular occlusion disturbances.BPC 157 was previously reviewed as novel mediator of Robert cytoprotection and endothelium protection in the stomach,and gut-brain axis,beneficial therapy in gastrointestinal tract,with particular reference to vascular recruitment,ulcerative colitis and tumor cachexia,and other tissues healing.Here we raised new hypothesis about BPC 157 therapy in the Budd-Chiari syndrome in rats,rapid bypassing of the suprahepatic inferior caval vein occlusion,and rats recovery with the active and effective pharmacotherapy treatment.AIM To investigate Budd-Chiari syndrome model(inferior caval vein suprahepatic occlusion)resolution,since BPC 157 resolves various rat vascular occlusion.METHODS We assessed the activated bypassing pathways between the inferior and superior caval veins and portocaval shunt,counteracted caval/portal hypertension,aortal hypotension,venous/arterial thrombosis,electrocardiogram disturbances,liver and gastrointestinal lesions(i.e.,stomach and duodenum hemorrhages,in particular,congestion).Rats with suprahepatic occlusion of the inferior vena cava by ligation were medicated at 1 min,15 min,24 h,or 48 h post-ligation.Medication consisted of 10μg/kg BPC 157,10 ng BPC 157 or 5 m L/kg saline,administered once as an abdominal bath or intragastric application.Gross and microscopic observations were made,in addition to assessments of electrical activity of the heart(electrocardiogram),portal and caval hypertension,aortal hypotension,thrombosis,hepatomegaly,splenomegaly and venography.Furthermore,levels of nitric oxide,malondialdehyde in the liver and serum enzymes were determined.RESULTS BPC 157 counteracted increased P wave amplitude,tachycardia and ST-elevation,i.e.,right heart failure from acute thrombotic coronary occlusion.The bypassing pathway of the inferior vena cava-azygos(hemiazygos)vein-superior vena cava and portocaval shunt occurred rapidly.Even with severe caval portal hypertension,BPC 157 antagonized portal and caval hypertension and aortal hypotension,and also reduced refractory ascites.Thrombosis of portal vein tributaries,inferior vena cava,and hepatic and coronary arteries was attenuated.In addition,there was reduced pathology of the lungs(severe capillary congestion)and liver(dilated central veins and terminal portal venules),decreased intestine hemorrhagic lesions(substantial capillary congestion,submucosal edema and architecture loss),and increased liver and spleen weight.During the period of ligation,nitric oxide-and malondialdehyde-levels in the liver remained within normal healthy values,and increases in serum enzymes were markedly reduced.CONCLUSION BPC 157 counteracts Budd Chiari syndrome in rats. | Slaven Gojkovic Ivan Krezic Borna Vrdoljak Dominik Malekinusic Ivan Barisic andreja Petrovic Katarina Horvat Pavlov Marijan Kolovrat Antonija Duzel Mario Knezevic Katarina Kasnik Kovac Domagoj Drmic Lovorka Batelja Vuletic Antonio Kokot Alenka Boban Blagaic Sven Seiwerth Predrag Sikiric | 2020 | World Journal of Gastrointestinal Pathophysiology2020，11，1： | 2 |
| 11 | Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights显示文摘AIM To provide new insights in treatment of colitis and ischemia and reperfusion in rats using stable gastric pentadecapeptide BPC 157. METHODS Medication [BPC 157,L-NAME,L-arginine(alone/combined),saline] was bath at the blood deprived colon segment. During reperfusion,medication was BPC 157 or saline. We recorded(USB microscope camera) vessel presentation through next 15 min of ischemic colitis(ICrats) or reperfusion(removed ligations)(IC + RL-rats);oxidative stress as MDA(increased(IC-and IC + RLrats)) and NO levels(decreased(IC-rats);increased(IC + RL-rats)) in colon tissue. IC + OB-rats [IC-rats had additional colon obstruction(OB)] for 3 d(IC + OBrats),then received BPC 157 bath. RESULTS Commonly,in colon segment(25 mm,2 ligations on left colic artery and vein,3 arcade vessels within ligated segment),in IC-,IC + RL-,IC + OB-rats,BPC 157(10 μg/kg) bath(1 m L/rat) increased vessel presentation,inside/outside arcade interconnections quickly reappeared,mucosal folds were preserved and the pale areas were small and markedly reduced. BPC 157 counteracted worsening effects induced by L-NAME(5 mg) and L-arginine(100 mg). MDA-and NO-levels were normal in BPC 157 treated IC-rats and IC + RLrats. In addition,on day 10,BPC 157-treated IC + OBrats presented almost completely spared mucosa with very small pale areas and no gross mucosal defects;the treated colon segment was of normal diameter,and only small adhesions were present.CONCLUSION BPC 157 is a fundamental treatment that quickly restores blood supply to the ischemically injured area and rapidly activates collaterals. This effect involves the NO system. | Antonija Duzel Josipa Vlainic Marko Antunovic Dominik Malekinusic Borna Vrdoljak Mariam Samara Slaven Gojkovic Ivan Krezic Tinka Vidovic Zdenko Bilic Mario Knezevic Marko Sever Nermin Lojo Antonio Kokot Marijan Kolovrat Domagoj Drmic Jaksa Vukojevic Tamara Kralj Katarina Kasnik Marko Siroglavic Sven Seiwerth Predrag Sikiric | 2017 | World Journal of Gastroenterology2017，23，48： | 2 |
| 12 | Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms显示文摘 | Ida Rasmusson Olle Ringdén Berit Sundberg Katarina Le Blanc | 2005 | Experimental Cell Research2005，，1： | 2 |
| 13 | Hematopoietic AMPK [Beta]1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity显示文摘 | Galic Sandra Fullerton Morgan D Schertzer Jonathan D Sikkema Sarah Marcinko Katarina Walkley Carl R Izon David Honeyman Jane Chen Zhi-Ping van Denderen Bryce J Kemp Bruce E Steinberg Gregory R | 2011 | Journal of Clinical Investigation2011，，12： | 2 |
| 14 | Counterregulation of insulin by leptin as key component of autonomic regulation of body weight显示文摘A re-examination of the mechanism controlling eating, locomotion, and metabolism prompts formulation of a new explanatory model containing five features: a coordinating joint role of the(1) autonomic nervous system(ANS);(2) the suprachiasmatic(SCN) master clock in counterbalancing parasympathetic digestive and absorptive functions and feeding with sympathetic locomotor and thermogenic energy expenditure within a circadian framework;(3) interaction of the ANS/SCN command with brain substrates of reward encompassing dopaminergic projections to ventral striatum and limbic and cortical forebrain. These drive the nonhomeostatic feeding and locomotor motivated behaviors in interaction with circulating ghrelin and lateral hypothalamic neurons signaling through melanin concentrating hormone and orexin-hypocretin peptides;(4) counterregulation of insulin by leptin of both gastric and adipose tissue origin through: potentiation by leptin of cholecystokinin-mediated satiation, inhibition of insulin secretion, suppression of insulin lipogenesis by leptin lipolysis, and modulation of peripheral tissue and brain sensitivity to insulin action. Thus weight-loss induced hypoleptimia raises insulin sensitivity and promotes its parasympathetic anabolic actions while obesity-induced hyperleptinemia supresses insulin lipogenic action; and(5) inhibition by leptin of bone mineral accrual suggesting that leptin may contribute to the maintenance of stability of skeletal, lean-body, as well as adipose tissue masses. | Katarina T Borer | 2014 | World Journal of Diabetes2014，5，5： | 2 |
| 15 | Immunobiology of Human Mesenchymal Stem Cells and Future Use in Hematopoietic Stem Cell Transplantation显示文摘 | Katarina Le Blanc Olle Ringdén | 2005 | Biology of Blood and Marrow Transplantation2005，，： | 2 |
| 16 | 湖泊中与微生物转化有关的氮素消涨显示文摘本研究观测了2个富营养化湖泊中微生物氮素的变化趋势,并与流入和流出湖泊的氮素消长情况进行了比较。浮游植物的初级生产力主要取决于再生氮素(尤其取决于铵态氮)的多少。浮游菌通过吸收溶解的游离氨基酸来满足其一年中大部分时间内对氮素的需求,并将相当大的一部分用于有机氮的再生。使硝酸盐变成分子态氮的微生物脱氮作用以及在沉积物中的永久性持留,是水生生态系统中氮素损耗的最主要途径。湖泊沉积物中的脱氮的估测方法是利用硝酸盐中的^(15)N作示踪物,然后测定所产生氮气的^(15)N/^(14)N比率而估算,并与以消涨计算得到的估测值进行比较,这两种方法得出了同水平估测值。由铵盐硝化作用得到的硝酸盐,马上就被作为脱氮作用的原料。脱氮作用每年的损耗量是外源氮素输入量的5%—25%,此值位于先前报道的变化范围的下限。湖泊沉积物中的氮素永久持留量是外源氮素输入量的14%—33%。 | Ingemar Ahlgren Tomas Waara Katarina Vrede Fred Srensson 马焕成 | 1994 | 人类环境杂志1994，23，6： | 2 |
| 17 | 散射介质中的气体吸收光谱技术对食品包装中氧气含量的光学无损检测显示文摘食品质量在很大程度上取决于食品的包装过程。为了抑制食品变质并延长货架期,食品包装技术在食品工业的应用得到了越来越广泛的发展。利用散射介质中的气体吸收光谱技术对食品包装中的气体含量进行光学无损检测。用中心波长为760 nm的二极管激光器测量食品包装中氧气的吸收光谱信号,通过研究包装内的气体交换过程估算出包装内的氧气体积分数。实验结果表明该技术可以用来测量食品包装中的氧气含量,确保食品包装的紧密型和安全性。 | 张浩 林惠莺 李天祺 段正 Katarina Svanberg Sune Svanberg | 2016 | 光学学报2016，36，2： | 2 |
| 18 | Functional studies of mesenchymal stem cells derived from adult human adipose tissue显示文摘 | Andrea Dicker Katarina Le Blanc Gaby ?str?m Vanessa van Harmelen Cecilia G?therstr?m Lennart Blomqvist Peter Arner Mikael Rydén | 2005 | Experimental Cell Research2005，，2： | 2 |
| 19 | Nitric oxide and tumour necrosis factor alpha in the process of pseudoexfoliation glaucoma显示文摘AIM: To establish the role of nitric oxide(NO), ascorbic acid and tumour necrosis factor α(TNF-α) in the pathogenesis of pseudoexfoliation glaucoma(XFG).METHODS: Our study included 120 patients who were referred for cataract surgery. All patients were divided into four groups according to clinical findings: XFG,early and late pseudoexfoliation syndrome(XFS), and cataract(without pseudoexfoliation). Serum and aqueous humour levels of the ascorbic acid, NO and TNF-α were measured. The concentrations of the ascorbic acid and NO were measured by an appropriate spectrophotometric method. Enzyme-linked immunosorbent assay(ELISA)was used to determine TNF-α level.RESULTS: Aqueous humour concentration of ascorbic acid was significantly lower in patients with late XFS(0.61 ±0.11 mmol/L) and XFG(0.48 ±0.15 mmol/L)compared to patients with early XFS(0.9 ±0.15 mmol/L)and cataract(1.16 ±0.22 mmol/L), while there was no difference in serum concentration in all examined groups.Aqueous humour concentration of NO was significantly higher in patients with XFG(77.7 ±11.4 μmol/L) compared to patients with early XFS(50.27 ±9.34 μmol/L) and cataract(49.77 ±7.1 μmol/L), while serum concentration was increased in the early stage of XFS(73.26±8.29 μmol/L).Aqueous humour level of proinflammatory cytokine TNF-αwas increased in patients with XFS(early 460.04±18.32 pg/mL;late 502.42±53.23 pg/mL) and XFG(510.34±43.07 pg/mL),while there was no difference in serum level in all examined groups of patients.CONCLUSION: Reduced ascorbic acid and elevated NO and inflammation related cytokine TNF-α level in aqueous humour of the patients with developed XFG suggest that oxidative stress induces local inflammation. | Tatjana S.Sarenac Vulovic Sladjana M.Pavlovic Vladimir LJ.Jakovljevic Katarina B.Janicijevic Nemanja S.Zdravkovic | 2016 | International Journal of Ophthalmology(English edition)2016，9，8： | 2 |
| 20 | Synthesis of a chitosan-based chelating resin and its application to the selective concentration and ultratrace detemination of silver in environmental water samples显示文摘 | Rosi Ketrin Katarina Toshio Takayanagi Mitsuko O shima | 2006 | Analytical Chimica Acta2006，，558： | 1 |
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