|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevention of esophageal strictures after endoscopic submucosal dissection显示文摘Endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD) have recently been accepted as less invasive methods for treating patients with early esophageal cancers such as squamous cell carcinoma and dysplasia of Barrett's esophagus.However,the large defects in the esophageal mucosa often cause severe esophageal strictures,which dramatically reduce the patient's quality of life.Although preventive endoscopic balloon dilatation can reduce dysphagia and the frequency of dilatation,other approaches are necessary to prevent esophageal strictures after ESD.This review describes several strategies for preventing esophageal strictures after ESD,with a particular focus on anti-inflammatory and tissue engineering approaches.The local injection of triamcinolone acetonide and other systemic steroid therapies are frequently used to prevent esophageal strictures after ESD.Tissue engineering approaches for preventing esophageal strictures have recently been applied in basic research studies.Scaffolds with temporary stents have been applied in five cases,and this technique has been shown to be safe and is anticipated to prevent esophageal strictures.Fabricated autologous oral mucosal epithelial cell sheets to cover the defective mucosa similarly to how commercially available skin products fabricated from epidermal cells are used for skin defects or in cases of intractable ulcers.Fabricated autologous oralmucosal-epithelial cell sheets have already been shown to be safe. | Shinichiro Kobayashi Nobuo Kanai Takeshi Ohki Ryo Takagi Naoyuki Yamaguchi Hajime Isomoto Yoshiyuki Kasai Takahiro Hosoi Kazuhiko Nakao Susumu Eguchi Masakazu Yamamoto Masayuki Yamato Teruo Okano | 2014 | World Journal of Gastroenterology2014，20，41： | 12 |
| 2 | Coronary artery disease in type 2 diabetes mellitus:Recent treatment strategies and future perspectives显示文摘Patients with type 2 diabetes mellitus(T2DM) are at a higher risk of developing coronary artery disease(CAD) than are non-T2 DM patients. Moreover, the clinical outcomes in CAD with T2 DM are poor despite improvements in medications and other interventions. Coronary artery bypass grafting is superior to percutaneous coronary intervention in treating multivessel coronary artery disease in diabetic patients. However, selecting a revascularization strategy depends not only on the lesion complexity but also on the patient's medical history and comorbidities. Additionally, comprehensive risk management with medical and non-pharmacological therapies is important, as is confirmation regarding whether the risk-management strategies are being appropriately achieved. Furthermore, non-pharmacological interventions using exercise and diet during the earlier stages of glucose metabolism abnormalities, such as impaired glucose tolerance, might be beneficial in preventing the development or progression of T2 DM and in reducing the occurrence of cardiovascular events. | Ryo Naito Takatoshi Kasai | 2015 | World Journal of Cardiology2015，7，3： | 12 |
| 3 | Transcatheter arterial chemoembolization with a fine-powder formulation of cisplatin for hepatocellular carcinoma显示文摘AIM:To evaluate the efficacy of transcatheter arterial chemoembolization(TACE) using a suspension of a fine-powder formulation of cisplatin(DDPH) for hepatocellular carcinoma(HCC).METHODS:The study population was comprised of 164 patients who were treated by TACE alone.Of these patients,76 underwent TACE using a suspension of DDPH in lipiodol(LPD)(DDPH group),and the remaining 88 underwent TACE with an emulsion of doxorubicin(ADM) with LPD(ADM group).We compared the DDPH group with the ADM group in terms of the objective early response rate,progression free survival(PFS) and overall survival(OS).RESULTS:The objective early response rate in the DDPH group was significantly higher than that in the ADM group(54% vs 24%,P < 0.001).The PFS rate in the DDPH group was also significantly higher than that in the ADM group(P < 0.001).Moreover,the OS in the DDPH group was significantly longer than that in the ADM group(P = 0.002).Although the incidence rate of nausea or vomiting in the DDPH group was higher than that in the ADM group,the ADM group showed a higher incidence rate of the adverse events of hepatic arterial damage and leucopenia.No other serious complications were observed in either group.CONCLUSION:We conclude that TACE using a suspension of DDPH in LPD could be a useful treatment for HCC. | Kazuhiro Kasai Akira Ushio Kei Sawara Yasuhiro Miyamoto Yukiho Kasai Kanta Oikawa Hidekatsu Kuroda Yasuhiro Takikawa Kazuyuki Suzuki | 2010 | World Journal of Gastroenterology2010，16，27： | 6 |
| 4 | Numerical and Experimental Investigation on Heat Propagation Through Composite Sinter Bed With Non-Uniform Voidage:Part Ⅰ Mathematical Model and Its Experimental Verification显示文摘The mechanisms of heat transfer through the sinter beds of the MEBIOS process are discussed and their comprehensive mathematical model is proposed.The MEBIOS process,the concept of which has been proposed earlier by the authors,allows using both coarse and fine particles of iron ores in the same sinter bed.The study includes two parts.The first part describes the model content and the results of its experimental verification.The model accounts for coal combustion,limestone decomposition,moisture evaporation/condensation,and melting/solidifying of solid phases.The model predictions are in good agreement with the experimental data.Typical numerical results of the sintering process and the key parameters influencing the process efficiency are discussed in the second part of the study. | Sergey V Komarov Hiroyuki Shibata Naohito Hayashi Eiki Kasai | 2010 | Journal of Iron and Steel Research(International)2010，17，10： | 5 |
| 5 | Therapeutic efficacy of transarterial chemo-embolization with a fine-powder formulation of cisplatin for hepatocellular carcinoma显示文摘AIM:To evaluate the efficacy of transarterial chemoembolization(TACE) using a suspension of a finepowder formulation of cisplatin(DDPH) in lipiodol(LPD) in the treatment of hepatocellular carcinoma(HCC).METHODS:The subjects were 262 HCC patients treated with TACE using a DDPH-LPD suspension.The DDPH-LPD suspension was prepared by mixing 50 mg of DDPH into 10 mL of LPD.TACE was repeated when treated lesions relapsed and/or new hepatic lesions were detected.These patients received additional TACE using the same agent.TACE was repeated until complete regression of the tumor was obtained.The primary efficacy endpoint of the current study was the objective early response rate.Secondary efficacy endpoints were progression-free survival(PFS) and overall survival.RESULTS:The objective early response rate was 43.6%.Cumulative PFS rates were 56.7% at 6 mo,23.1% at 12 mo,13.4% at 18 mo,and 10.5% at 24 mo.The median PFS was 6.6 mo.Cumulative survival rates were 90.6% at 6 mo,81.9% at 12 mo,70.5% at 24 mo,and 58.8% at 36 mo.Median survival time was 46.6 mo.All adverse reactions were controllable by temporary suspension of treatment.No serious complications or treatment-related deaths were observed.CONCLUSION:TACE using a suspension of DDPH in LPD may be a useful treatment for HCC. | Kazuhiro Kasai Akira Ushio Yukiho Kasai Kei Sawara Yasuhiro Miyamoto Kanta Oikawa Yasuhiro Takikawa Kazuyuki Suzuki | 2013 | World Journal of Gastroenterology2013，19，14： | 3 |
| 6 | 伊朗Graves眼病的临床特点(英文)显示文摘目的:研究分析伊朗Graves眼病患者的临床特点。方法:回顾分析2003/2005年确诊为Graves眼病的103例患者临床资料。结果:在103例Graves眼病患者中,48例(46.6%)为男性,55例(53.3%)为女性(男女比例为1.1)。年龄18~73(平均45)岁,95例(92.2%)表现为甲状腺机能亢进,3例(2.9%)表现为原发性甲状腺机能减退,5例(4.8%)甲状腺机能正常。出现眼部症状的时间为2~95(平均3.2)mo,而表现出甲状腺功能障碍的时间为6~180(平均39.4)mo。12例患者单眼发病,90例(87%)患者有眼睑退缩,80例(77.6%)患者表现出眼球突出,其中30例(29%)伴有局限性眼外肌运动障碍;CT扫描显示70例患者中有52例(74%)有眼外肌肥大。6例患者(5.8%)有视神经功能障碍,22例患者(21%)表现出Graves眼病相关的青光眼,其中7例(6.7%)为正常眼压青光眼。结论:本组病例中眼睑退缩是Graves眼病最常见的临床表现。未来需要更大范围的病例研究,以评价分析Graves眼病在伊朗人群中的发病率以及不同人种之间临床表现差异。 | Ali Sadeghi Tari Mohammad Taher Rajabi Khalil Hamzedust Seyed Ziaeddin Tabatabaie Abolfazl Kasai | 2007 | 国际眼科杂志2007，7，2： | 3 |
| 7 | Vaporization behavior of lead from the FeO-CaO-SiO_2-Al_2O_3 slag system显示文摘Vaporization behavior (1163-1463 K) of lead in the slag system of FeO-CaO-SiO2-Al2O3 with CaCl2 was examined. A thermodynamic estimation with the principle of Gibbs free energy minimization showed that the major vapor species from the sam-ple of the FeO-CaO-SiO2-Al2O3 system+PbO+CaCl2 were metallic Pb, PbCl, PbCl2, and FeCl2, at the experimental temperature range. The experimental results show that the mole ratio of vaporized Cl in lead chlorides to vaporized Pb, simply expressed as Cl/Pb, decreases with increasing temperature. The larger Cl/Pb means a larger ratio of gaseous PbCl2, since metallic Pb and PbCl vapors are formed in a similar reduction atmosphere. The evaporation is initially rapid and becomes steady after holding for 10 min. Gaseous PbCl2 is mainly formed during the heating period, and at the holding stage, it reacts with FeO to produce gaseous FeCl2. With regard to slag composition, FeO content and basicity significantly affect the evaporation of lead. High FeO content and high basicity pro-motes the formation of metallic Pb and PbCl, whereas, it prohibits PbCl2 evaporation. | Yanling Zhang Rui Zhang Eiki Kasai Shiqi Li | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 3 |
| 8 | Study on Improvement of Seismic Performance of Transmission Tower Using Viscous Damper显示文摘 | Masayuki Matsumoto Akira Kasai Taiji Mazda Nobuyuki Ishida Yuki Ito | 2017 | Journal of Civil Engineering and Architecture2017，11，5： | 3 |
| 9 | 显示文摘 | Chahara K Ohno T Kasai M | 1993 | Appl Phys Lett1993，63，： | 2 |
| 10 | Metformin Inhibits Cytokine-Induced Nuclear Factor κB Activation Via AMP-Activated Protein Kinase Activation in Vascular Endothelial Cells显示文摘 | Yoshiyuki Hattori Kunihiro Suzuki Sachiko Hattori Kikuo Kasai | 2006 | Hypertension2006，，6： | 2 |
| 11 | A simple method for mouse embry cryopreservation in a low toxicity vitrification solution, without appreciable loss of viability显示文摘 | Kasai M Komi J H Takakamo A | 1990 | J Reprod Fertil1990，89，： | 2 |
| 12 | Cryopreservation of expanded mouse blastocyssts by vitrification in ethylene glycol-based solution显示文摘 | Zhu S E Kasai M Otoge H | 1993 | J Reprod Fertil1993，98，： | 2 |
| 13 | Full-scale dynamic testing of response-controlled buildings and their components:concepts,methods,and findings显示文摘A series of shake-table tests was conducted by inserting and replacing 4 different types of dampers,or by removing them in a full-scale 5-story steel frame building. The objective is to validate response-control technologies that are increasingly adopted for major Japanese buildings without being attested to-date by a major earthquake. Test results are briefly described,and good performance of the dampers and frame demonstrated. The concepts of the full-scale building tests and various contributions are discussed. The difficulty associated with full-scale dynamic testing is explained. | Kazuhiko Kasai Kazuhiro Matsuda | 2014 | Earthquake Engineering and Engineering Vibration2014，13，S1： | 2 |
| 14 | Analytical studies on local damage to reinforce concrete structures under impact loading by discrete element method显示文摘 | Sawamoto Y Tsubota H Kasai Y | 1998 | Nuclear Engineering and Design1998，179，： | 1 |
| 15 | New sweet diterpene glucosides from Stevia rebaudiana显示文摘 | Hiroshi Kohda Ryoii Kasai Kazuo Yamasaki | 1976 | Phytochemistry1976，15，6： | 1 |
| 16 | A kinematic analysis of disk motion in a double sided polisher for chemical mechanical planarization (CMP) 显示文摘 | Toshi Kasai | 2008 | Tribology International2008，41，： | 1 |
| 17 | Sarcomatiod carcinoma of the lung:a clinicopathologic study of 37 cases显示文摘 | Nakajima m kasai t Hashimoto h | 1999 | Ccancer1999，86，： | 1 |
| 18 | Transmission of an azole-resistant isogenic strain of Candida albicans among human immunodeficiency virus-infected family members with oropharyngeal candidiasis显示文摘 | Kasai M Francesconi A | 1999 | J Clin Microbiol1999，37，10： | 1 |
| 19 | Glycomics,coming of age显示文摘 | Kasai K | 2000 | Trends Glycosci Glycotech2000，，12： | 1 |
| 20 | Chemical Shrinkage and Autogeneous Shrinkage of Hydrating Cement Paste显示文摘 | Tazawa E Miyazawa S Kasai T | 1995 | Cem Coner Res1995，25，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员