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| 1 | 溶栓时间(入院到用药时间)的延迟及其对脑卒中治疗时间与预后的影响显示文摘尽管美国心脏协会/美国脑卒中协会关于脑卒中的治疗均提出了倡议,大量急性缺血性脑卒中患者仍然在到达就诊60min后才开始启动组织型纤溶酶原激活剂(阿替普酶)溶栓治疗。该研究旨在描述延迟的原因及其与患者预后之间的关系。 | 刘莉 叶鹏 Kamal N Sheng S Xian Y Matsouaka R Hill MD Bhatt DL Saver JL Reeves MJ Fonarow GC Schwamm LH Smith EE | 2017 | 中华高血压杂志2017，25，4： | 15 |
| 2 | Intensivist-based deep sedation using propofol for pediatric outpatient flexible bronchoscopy显示文摘AIM To evaluate the safety and efficacy of sedating pediatric patients for outpatient flexible bronchoscopy.METHODS A retrospective chart review was conducted for all children, age 17 years or under who underwent flexible bronchoscopy under deep sedation in an outpatient hospital-based setting. Two sedation regimens were used; propofol only or ketamine prior to propofol. Patients were divided into three age groups; infants(less than 12 mo), toddlers(1-3 years) and children(4-17 years). Demographics, indication for bronchoscopy, sedative dosing, sedation and recovery time and adverse events were reviewed.RESULTS Of the total 458 bronchoscopies performed, propofol only regimen was used in 337(74%) while propofol and ketamine was used in 121(26%). About 99% of the procedures were successfully completed. Children in the propofol + ketamine group tend to be youngerand have lower weight compared to the propofol only group. Adverse events including transient hypoxemia and hypotension occurred in 8% and 24% respectively. Median procedure time was 10 min while the median discharge time was 35 min. There were no differences in the indication of the procedure, propofol dose, procedure or recovery time in either sedative regimen. When compared to other age groups, infants had a higher incidence of hypoxemia.CONCLUSION Children can be effectively sedated for outpatient flexible bronchoscopy with high rate of success. This procedure should be performed under vigilance of highly trained providers. | Kamal Abulebda Samer Abu-Sultaneh Sheikh Sohail Ahmed Elizabeth A S Moser Renee C McKinney Riad Lutfi | 2017 | World Journal of Critical Care Medicine2017，6，4： | 8 |
| 3 | Response of blood pressure after percutaneous transluminal renal artery angioplasty and stenting显示文摘AIM: To evaluate the short and intermediate term out-come of percutaneous transluminal renal artery angioplasty (PTRA) and stenting particularly on blood pressure (BP) control and renal function and to evaluate predictors of poor BP response after successful PTRA and stenting. METHODS: We conducted a prospective analysis of all patients who underwent PTRA and stenting in our institute between August 2010 to September 2012. A total number of 86 patients were underwent PTRA and renal stenting. Selective angiography was done to confirm at least 70% angiographic stenosis. The predilatation done except few cases with critical stenosis, direct stenting was done in the rest of cases. All patients received aspirin 325 mg orally, and clopidogrel 300 mg orally within 24 h before the procedure. Heparin was used as the procedural anticoagulant agent. Optimal results with TIMI-Ⅲ flow obtained in all cases. Following stent placement, aspirin 150 mg orally once daily was continued for a minimum of 12 mo and clopidogrel 75 mg orally once daily for at least 4 wk. The clinical, radiological, electrocardiography, echocardiography and treatment data of all patients were recorded. The BP measurement, serum creatinine and glomerular filtration rate (GFR) were recorded before the procedure and 1 and 6 mo after PTRA. RESULTS: A total of 86 patients were included in the study. The mean age of study population was 55.87±11.85 years old and 67 (77.9%) of patients were male. There was a significant reduction in both systolic and diastolic BP at 1 mo after the procedure: 170.15±20.10 mmHg vs 146.60±17.32 mmHg and 98.38±10.55 mmHg vs 89.88±9.22 mmHg respectively (P=0.0000). The reduction in BP was constant throughout the follow-up period and was evident 6 mo after the procedure: 144.23±18.19 and 88.26±9.79 mmHg respectively (P=0.0000). However, no improvement in renal function was observed at any time during the follow-up period. After multivariate analysis, we found male sex, low GFR (<60 mL/min) and higher baseline mean BP as a poor predictors of successful outcome on BP response after PTRA and stenting. CONCLUSION: The PTRA and stenting can be considered as an effective therapeutic intervention for improving BP control with minimal effect on renal function. The male sex, higher baseline BP and low GFR are associated with poor BP response after successful PTRA and stenting. | Jayesh S Prajapati Sharad R Jain Hasit Joshi Shaurin Shah Kamal Sharma Sibasis Sahoo Kapil Virparia Ashok Thakkar | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 4 | Lipoprotein abnormalities in South Asians and its association with cardiovascular disease:Current state and future directions显示文摘South Asians have a high prevalence of coronary heart disease(CHD) and suffer from early-onset CHD compared to other ethnic groups. Conventional risk factors may not fully explain this increased CHD risk in this population. Indeed, South Asians have a unique lipid profile which may predispose them to premature CHD. Dyslipidemia in this patient population seems to be an important contributor to the high incidence of coronary atherosclerosis. The dyslipidemia in South Asians is characterized by elevated levels of triglycerides, low levels of high-density lipoprotein(HDL) cholesterol, elevated lipoprotein(a) levels, and a higher atherogenic particle burden despite comparable low-density lipoprotein cholesterol levels compared with other ethnic subgroups. HDL particles also appear to be smaller, dysfunctional, and proatherogenic in South Asians. Despite the rapid expansion of the current literature with better understanding of the specific lipid abnormalities in this patient population, studies with adequate sample sizes are needed to assess the significance and contribution of a given lipid parameter on overall cardiovascular risk in this population. Specific management goals and treatment thresholds do not exist for South Asians because of paucity of data. Current treatment recommendations are mostly extrapolated from Western guidelines. Lastly, large, prospective studies with outcomes data are needed to assess cardiovascular benefit associated with various lipid-lowering therapies(including combination therapy) in this patient population. | Ozlem Bilen Ayeesha Kamal Salim S Virani | 2016 | World Journal of Cardiology2016，8，3： | 3 |
| 5 | Antidepressant bupropion exerts alleviating properties in an ovariectomized osteoporotic rat model显示文摘 | Hatem M ABUOHASHISH Mohammed M AHMED Salim S AL-REJAIE Kamal EH ELTAHIR | 2015 | Acta Pharmacologica Sinica2015，36，2： | 2 |
| 6 | Imaging pancreatobiliary ductal system with optical coherence tomography: A review显示文摘An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography(OCT) is a noninvasive, high-resolution(1-10 μm) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by inserting an OCT probe through a standard endoscope operative channel. High-resolution OCT images and the technique's endoscopic compatibility have allowed for the microstructural diagnostic of thepancreatobiliary diseases. In this review, we discussed currently available pancreaticobiliary ductal imaging systems to assess the pancreatobiliary tissue microstructure and to evaluate varieties of pancreaticobiliary disorders and diseases. Results show that OCT can improve the quality of images of pancreatobiliary system during endoscopic retrograde cholangiopancheatography procedure, which may be important in distinguishing between the neoplastic and non-neoplastic lesions. | Mohammad S Mahmud Gray R May Mohammad M Kamal Ahmed S Khwaja Carry Sun Alex Vitkin Victor XD Yang | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 2 |
| 7 | In vitro evolved non-aggregating and thermostable lipase:structural and thermodynamic investigation显示文摘 | Kamal M Z Ahmad S Molugu T R | 2011 | J Mol Biol2011，413，： | 1 |
| 8 | Ecological vehicle control on roads with up-down slopes显示文摘 | KAMAL M A S MUKAI M MURATA J | 2011 | IEEE Trans Intell Transp Syst2011，12，3： | 1 |
| 9 | Long - term moisture absorption and thickness swelling behavior of recycled thermoplastics reinforced with Pinus radiata sawdust 显示文摘 | Kamal B A Shusheng P Mark P S | 2008 | Chemical Engineering Journal2008，142，2： | 1 |
| 10 | Kinetics and thermal characterization of thermoset cure 显示文摘 | Kamal M R Sourour S | 1973 | Polym Eng Sci1973，13，1： | 1 |
| 11 | A multilevel automatic thresholding method based on a genetic algorithm for a fast image segmentation 显示文摘 | Kamal H Moussa D Patrick S | 2008 | Comp Vision Image Un- derstand2008，109，2： | 1 |
| 12 | High Temperature Cyclic Oxidation and Hot Corro- sion Behaviours of SuperaUoys at 900 :C 显示文摘 | KAMAL S JAYAGANTHAN R PRAKASH S | 2010 | Bulle- tin of Materials Science2010，33，3： | 1 |
| 13 | Thermostable Bacillus subtilis lipases:in vitro evolution and structural insight显示文摘 | Ahmad S Kamal M Z Sankaranarayanan R | 2008 | J Mol Biol2008，381，： | 1 |
| 14 | Synthesis and Biological Evaluation of Tetracyclic Fluoroquinolones asAntibacterial and Anticancer Agents显示文摘 | Al-Trawneh S A Zahra J A Kamal M R | 2010 | Bioorg Med Chem2010，18，： | 1 |
| 15 | Development of ANN-based virtual fault detector for Wheatstone bridge -oriented transducers 显示文摘 | Singh A P Kamal T S Kumar S | 2005 | Sensors Journal2005，5，5： | 1 |
| 16 | Adsorption of fluoride from water by Al^3+ and Fe^3_ pretreated natural iranian zeolites显示文摘 | Rahmani A Nouri J Kamal Ghadiri S | 2010 | International Journal of Environmental Research2010，4，4： | 1 |
| 17 | The Development of Laminar Morphology During Extrusion of Polymer Blends显示文摘 | Kamal M R Garmabi H Hozhabr S | 1995 | Polym Eng Sci1995，35，： | 1 |
| 18 | Ultraweak photon emission and proteomics analyses in soybean under abioticstress显示文摘 | Komatsu S Hena A Kamal M | 2014 | Biochimica et Biophysica Acta2014，1844，4： | 1 |
| 19 | Anaerobic phototrophic metabolism of 3-chlorobenzoate by Rhodopseudomonas palustris显示文摘 | KAMAL S WYNDI4AM R C | 1990 | Appl Environ Microbiol1990，56，12： | 1 |
| 20 | Catalytic decompo-sition of ethanol on V2O5/AIPO4 catalysts 显示文摘 | Abd El-Aziz A Said Kamal M S Khalil | 2000 | Journal ofChemical Technology and Biotechnology2000，75，： | 1 |
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