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| 1 | Intravaginal gels as drugdelivery systems显示文摘 | Justin TM Darnian F Kinget R | 2004 | J Womens Health(Larchmt)2004,13,7: | 1 |
| 2 | Causes, magnitude and man- agement agement of burns in under-fives in district hospitals in Dares Salaam,Tanzania显示文摘 | Justin TM Rimoy G Premji Z | 2008 | East Afr J Public Health2008,5,1: | 1 |
| 3 | Causes,magnitude and management of burns in under-fives in district hospitals in Dar es Salaam,Tanzania显示文摘 | Justin TM Rimoy G Premji Z | 2008 | East Afr J Public Health2008,5,1: | 1 |
| 4 | Causes,magnitude and management agement of burns in under-fives in district hospitals in Dar es Salaam,Tanzania显示文摘 | Justin TM Rimoy G Premji Z | | 0,,01: | 1 |
| 5 | Causes, magnitude and management of burns in under-fives in district hospitals in Dar es Salaam, Tanzania 显示文摘 | Justin TM Rimoy G Premji Z | 2008 | East-Mr-J-Public-Health2008,5,1: | 1 |
| 6 | Highly cross-linked versus conventional polyethylene inserts in total hip arthroplasty,a five-year Roentgen stereophotogrammetric analysis randomised controlled trial显示文摘BACKGROUND Polyethylene(PE)particles produced by wear of the acetabular insert are thought to cause osteolysis and thereby aseptic loosening of the implant in total hip arthroplasty(THA).As highly cross-linked polyethylene(HXLPE)is presumed to give lower wear rates,in vivo studies are needed to confirm this.AIM To compare the wear of REXPOL,a HXPLE,with conventional PE within the first five years after implantation using Roentgen stereophotogrammetric analysis(RSA).METHODS Patients were randomised to receive either a HXLPE(REXPOL)or a conventional PE insert during primary THA.RSA images were obtained directly postoperative and after 6 wk,12 wk,6 mo,12 mo,24 mo and five years.Functional outcomes were assessed using the Hip Injury and Osteoarthritis Outcome Score and Harris Hip Score at baseline and five years after surgery.RESULTS The HXLPE(REXPOL)showed less wear in the latero-medial direction.Significant wear rates of conventional PE were seen in the latero-medial and center-proximal direction and in volume and corrected volume,whereas the REXPOL did not show these outcomes over time.Improvement from baseline in functional outcome did not significantly differ.CONCLUSION Total 3D wear is less in THAs inserted with a REXPOL inlay than a conventional PE inlay after five years.This study confirms,for the first,that the REXPOL HXLPE inlay is preferred to standard PE. | Justin van Loon Daniël Hoornenborg Inger Sierevelt Kim TM Opdam Gino MMJ Kerkhoffs Daniël Haverkamp | 2020 | World Journal of Orthopedics2020,11,10: | 0 |
| 7 | Ceramic-on-ceramic vs ceramic-on-polyethylene,a comparative study with 10-year follow-up显示文摘BACKGROUND In press-fit total hip arthroplasty(THA)ceramic-on-ceramic(CoC)bearings are a potential for overcoming the wear that is seen in ceramic-on-polyethylene(CoPE)bearings,and can lead to wear-induced osteolysis,resulting in loosening of the implant.However,CoC bearings show disadvantages as well,such as squeaking sounds and being more fragile,which can cause ceramic head or liner fracture.Because comparative long-term studies are limited,the objective of this study was to determine the long-term difference in wear,identify potential predictive factors for wear,investigate radiological findings such as osteolysis,and evaluate clinical functioning and complications between these bearings.AIM To determine 10-year differences in wear,predictive factors for wear,and investigate radiological findings and clinical functioning between CoC and CoPE.METHODS This observational prospective single-center cohort study with a 10-year followup includes a documented series of elective THAs.Primary outcome was wear measured by anteroposterior(AP)radiographs.Secondary outcomes were potential predictive factors for wear,complications during follow-up,Harris hip score(HHS),and radiological findings such as presence of radiolucency,osteolysis,atrophy,and hypertrophy around the cup.Due to the absence of wear in the CoC group,stratified analysis to identify risk factors for wear was only performed in the CoPE group by use of univariate linear regression analysis.HHS was expressed as a change from baseline and the association with bearing type was assessed by use of multivariate linear regression analysis,adjusted for potential confounders.RESULTS A total of 17 CoPE(63.0%)and 25 CoC(73.5%)cases were available for follow-up and showed a linear wear of respectively 0.130 mm/year(range 0.010;0.350)and 0.000 mm/year(range 0.000;0.005),which was significant(P<0.001)between both groups.Wear always occurred in the cranial direction.Cup inclination was the only predictive factor for polyethylene(PE)wear.No dislocations,ceramic head,or liner fractures were seen.The HHS showed a mean change from baseline of 37.1 points(SD 18.5)in the CoPE group and 43.9(SD 17.0)in the CoC group.This crude difference of 6.8(range-5.2;18.7)in favor of the CoC group was not significant(P=0.26)and was not significant when adjusted for age,gender,and diagnosis either(P=0.99).No significant differences in complications and radiological findings were seen between groups.CONCLUSION CoC bearing shows lower wear rates compared to CoPE at 10-year follow-up with cup inclination as a predictive factor for wear and no differences in complications,HHS,and radiological findings. | Justin van Loon Daniël Hoornenborg Harm M van der Vis Inger N Sierevelt Kim TM Opdam Gino MMJKerkhoffs Daniël Haverkamp | 2021 | World Journal of Orthopedics2021,12,1: | 0 |