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111篇 您的检索式:作者名="Jusko"
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1电阻抗断层成像与乳房超声及钼靶在诊断乳腺良恶性病变中的对照观察显示文摘目的探讨一种新的电阻抗断层成像技术(EIT)对乳腺良恶性疾病的诊断价值,并与传统的影像学检查乳房超声和钼靶的结果进行比较。方法2016年5至8月来北京朝阳医院乳腺外科就诊的121例患者,共126个乳腺结节接受钼靶、超声及EIT检查,均经穿刺活检或手术病理证实,计算EIT、超声和钼靶检查对乳腺病变的准确率、敏感度、特异度、阳性预测值、阴性预测值。结果EIT、超声及钼靶检查对乳腺良恶性病变诊断的准确率分别为75.4%、81.7%、76.1%,敏感度分别为76.8%、94.6%、74.4%,特异度分别为74.3%、71.4%、77.6%,EIT结合超声诊断乳腺病变的准确度、敏感度和特异度分别为91.3%、98.2%、85.7%,在准确度和特异度方面显著高于超声检查(χ^2=4.896,P=0.027;χ^2=4.242,P=0.039),EIT联合钼靶对乳腺病变的诊断准确率、敏感度及特异度分别为95.5%,97.4%,93.9%,均显著高于钼靶检查(χ^2=13.474,P〈0.001;χ^2=8.573,P=0.003;χ^2=5.333,P=0.021)。结论电阻抗断层成像对超声和钼靶在诊断乳腺疾病时有良好的互补性,且能够对乳腺进行代谢评估,有望用于早期筛查。徐峰 李梦新 Peter Jusko 蒋宏传 2017中华医学杂志2017,97,18:15
2Prednisolone disposition in obese men显示文摘Milsap RL Plaisance KI Jusko WJ 1984Clin Pharmacol Ther1984,36,6:1
3Utility of cleavable isotopecoded affinity - tagged reagents for quantification of low - copy proteins induced by methylprednisolone using liquid chromatography/tandem mass spectrometry 显示文摘Qu J Jusko W J Straubinger R M 2006Anal Chem2006,78,:1
4Consensus document : therapeutic monitoring of taerolimus ( FK-506 ) 显示文摘Jusko WJ Thomson AW Fung J 1995Ther Drug Monit1995,17,4:1
5Cortieosteroid pharmacodynamie modeling: osteocalcin suppression by prednisolone 显示文摘Jeffrey A Wald Jusko J 1992Pharmaceutical Research1992,9,:1
6Pharmacokinetics of tacrolimus in liver transplant patients 显示文摘Jusko WJ Piekoszewski W Klintmalm GB 1995Clin Pharmacol Ther1995,57,:1
7Consensus Document:Therapeutic Monitoring of Tacrolimus (FK506)显示文摘Jusko WJ Thomson AW Fung J 1995Ther Drog Morit1995,17,6:1
8Modeling interaction between adrenal suppression and T-helper lymphocyte trafficking during multiple dosing of methylprednisolone显示文摘Chow FS Sharma A Jusko WJ 1999J Pharmacokinet Biopharm1999,27,6:1
9Consensus document: therapeutic monitoring of tacrolimus (FK-506)显示文摘Jusko WJ Thomson AW Fung J 1995Ther Drug Monit1995,17,6:1
10Physiologic indirect response models characterize diverse typesof pharmacodynamic effects 显示文摘Jusko WJ Ko HC 1994Clin Pharmacol Ther1994,56,:1
11Consensus document: therapeutic monitoring of tacrolimus (FK506) 显示文摘JUSKO W J THOMSON A W FUNG J J 1995Ther Drug Monit1995,17,6:1
12Betamethasone pharmacokinetics after two prodrug formulations in sheep: implications for antenatal corticosteroid use显示文摘Samtani M N Lohle M Grant A Nathanielsz P W Jusko W J 2005Drug Metab Dispos2005,33,:1
13Blood lead concentrations < 10 μg/dL and child intelligence at 6 years of age显示文摘Jusko TA Henderson CR Lanphear BP 2008Environ Health Perspect2008,116,2:1
14Quantitative structure-pharmacokinetic/pharmacodynamic relationships of corticosteroids in man显示文摘Mager DE Jusko WJ 2002J Pharm Sci2002,91,:1
15Blood Lead Concentrations < 10μg/dL and Child Intenigence at 6 Years of Age 显示文摘Jusko T A Henderson Jr C R Lanphear B P 2008Environ Health Perspect2008,116,:1
16Pharmacokinetics and receptor-mediated pharmacodynamis of corticosteroids显示文摘Jusko WJ 1995Toxicology1995,102,:1
17Scaling Pharmacodynamics from in vitro and preclinical animal studies to humans显示文摘Mager DE Woo S Jusko WJ 2009Drug Metab Pharmacokinet2009,24,1:1
18Identifying peer-to-peer communities in the network by connection graph analysis显示文摘Jusko J Rehak M 2014International Journal of Network Management2014,24,4:1
19Dose-dependence and repeated-dose studies for receptor / genemediated pharmacodynamic of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aninotransferase induction in rat liver显示文摘 DuBios DC Almon RR Pyszczyhski NA Jusko WJ 1998J Pharmacokinet Biopharm1998,26,6:1
20Comparison of 4 basic models of indirectpharmacodynamic responses显示文摘Dayneka NL Garg V Jusko WJ 1993J Pharmacokinet Biop1993,21,:1
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