|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Construction, characterization and application of a genomewide promoter library in Saccharomyces cerevisiae显示文摘倡导者们是批评元素控制基因表示,但是能在各种各样的生长条件下面不同地表现。这里,我们报导一个染色体宽的倡导者图书馆,在 Saccharomyces cerevisiae 的每个本国的倡导者在被克隆的构造黄在上游荧光灯蛋白质(YFP ) 记者基因。九个图书馆任意地在细菌被定义并且集合。倡导者的产生水池能被准备并且也作为 centromeric plasmids 转变了成酵母紧张或集成于在酶的处理之上的一个 genomic 地点。使用荧光激活房间排序,我们基于 YFP 荧光紧张分类酵母紧张并且任意地把全部图书馆划分了成 12 箱,代表对强壮的倡导者弱。几个强壮的倡导者从最活跃的箱被识别,他们的活动是在不同生长条件下面的 assayed。最后,这些倡导者被使用在木糖利用驱使基因的表示改进发酵效率。一起,这个图书馆能提供一个快答案在自定义生长条件下面识别并且利用需要的倡导者。 | Ting Yuan Yakun Guo Junkai Dong Tianyi Li Tong Zhou Kaiwen Sun Mei Zhang Qingyu Wu Zhen Xie Yizhi Cai Limin Cao Junbiao Dai | 2017 | Frontiers of Chemical Science and Engineering2017，11，1： | 1 |
| 3 | Inhibition of the negative effect of high glucose on osteogenic differentiation of bone marrow stromal cells by silicon ions from calcium silicate bioceramics显示文摘Human bone marrow stem cells(hBMSCs)are exploited for miscellaneous applications in bone tissue engineering where they are mainly used as seed cells.However,high glucose(HG)environment has negative impacts on the proliferation and osteogenic differentiation of hBMSCs,thus reducing the bone formation in diabetic patients.In our former research works,we discovered that silicon(Si)ions extracted from silicate-based bioceramics are able to stimulate the proliferation and osteogenic differentiation of hBMSCs under normal culture condition.This study aimed to investigate if Si ions could prevent HG-induced inhibition of proliferation and osteogenesis of hBMSCs.We found that 2.59ppm concentration of Si ions promoted the proliferation of hBMSCs under HG condition.The results from alkaline phosphatase(ALP)activity assay,Alizarin red S staining and quantitative real-time PCR analysis of osteogenic genes(BMP2,RUNX2,ALP,COL1 and OCN)demonstrated that the 15.92ppm concentration of Si ions prevented HG-induced inhibition of the osteogenic differentiation of hBMSCs.Moreover,application of Si ions reduced the level of reactive oxygen species in HG-treated hBMSCs.In HG-treated hBMSCs following 15.92ppm Si ions treatment,activation of BMP2/SMAD signaling pathway was detected,as indicated by the increased expression of BMP2 receptors and its downstream genes such as SMAD1,SMAD4 and SMAD5.Taken together,we provide evidence that the specific concentration of Si ions compensated HG-induced inhibition of proliferation and osteogenic differentiation of hBMSCs through antioxidant effect and modulation of BMP2/SMAD pathway.The results suggest that silicate-based bioceramics might be good scaffold biomaterials for bone engineering applications in diabetes patients. | Xixi Dong Xiaoya Wang Min Xing Cancan Zhao Bin Guo Junkai Cao Jiang Chang | 2020 | Regenerative Biomaterials2020，7，1： | 1 |
| 4 | Synergistic effects of plant hormones on spontaneous late-ripening mutant of'Jinghong'peach detected by transcriptome analysis显示文摘Objectives:Peach(Prunus persica L.)is an ancient fruit tree that originated from China.It is the climacteric fruit belonging to genus Prunus in family Rosaceae.Ethylene,which is produced during ripening,accelerates fruit softening,and therefore peaches cannot be stored for a long time.Materials and Methods:To study the mechanism of fruit late ripening,transcriptome analysis of the fruit of a late-ripening mutant of'Jinghong'peach was performed to identify genes and pathways involved in fruit late ripening.Results:A total of 1805,1511,and 2309 genes were found to be differentially expressed in W2_vs_M1,W3_vs_M2,and W3_vs_M3,respectively.Functional enrichment analysis of the differentially expressed genes showed they were related to carotenoid biosynthesis,starch and sucrose metabolism plant hormone signal transduction,flavonoid biosynthesis,and photosynthesis.The expression trends of ripening-related genes that encode transcription factors and plant hormone signal transduction-related genes that encode enzymes were similar.Conclusions:It will help to elucidate the transcriptional regulatory network of fruit development in the spontaneous late-ripening mutant of‘Jinghong’peach and provide a theoretical basis for understanding the molecular regulatory mechanism of fruit ripening. | Man Zhang Tingting Du Yarui Yin Hongyan Cao Zhihua Song Mao Ye Yating Liu Yanhong Shen Libin Zhang Qing Yang Dong Meng Junkai Wu | 2022 | Food Quality and Safety2022，6，1： | 0 |
| 5 | Greenberger-Horne-Zeilinger test for multi-dimension and arbitrary time nodes entangled histories显示文摘Quantum entanglement,since proposed by Einstein,Podolsky and Rosen(EPR)[1]and further explored by Schr?dinger[2]in1935,has always been the focus of quantum physics realm.The EPR paradox revealed the conflict between quantum theory and local realism.Almost 30 years later,in 1964,Bell first came up with the prototype of a family of inequalities,which was later called Bell inequality[3,4],to express certain limitation that every local clas- | Junkai Dong Yi-Ming Chen Da Xu Zhang-Qi Yin | 2017 | Science Bulletin2017，62，18： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员