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| 1 | Platelets in Kawasaki disease:Is this only a numbers game or something beyond?显示文摘Kawasaki disease(KD)is a medium vessel vasculitis with predilection to cause coronary artery abnormalities.KD is now the most common cause of acquired heart disease in developed countries.Thrombocytosis is consistently found in patients with KD,usually in 2nd to 3rd week of illness.Thrombocytopenia has occasionally been reported in the acute phase of KD.An increase or decrease in platelet number in patients with KD was initially considered to be a benign phenomenon.However,recent literature on platelet biology in KD has suggested that platelets are not only increasing but are rather activated.This phenomenon has been found to increase the risk of thrombosis in these patients.Similarly a fall in platelet counts during acute stage of KD has also been found to be associated with increased severity of disease.In this review,we update on the current best understanding about pathogenic role of platelets in patients with KD. | Kanika Arora Sandesh Guleria Ankur Kumar Jindal Amit Rawat Surjit Singh | 2020 | Genes & Diseases2020，7，1： | 9 |
| 2 | Epidemiologic pattern of paediatric supracondylar fractures of humerus in a teaching hospital of rural India: A prospective study of 263 cases显示文摘 | Rashid Anjum Vivek Sharma Ramesh Jindal Tarun Pratap Singh Narender Rathee | 2017 | Chinese Journal of Traumatology2017，20，3： | 5 |
| 3 | Erlotinib usage after prior treatment with gefitinib in advanced non-small cell lung cancer: A clinical perspective and review of published literature显示文摘Erlotinib and gefitinib are among the most widely researched, used and available molecularly targeted therapies for treatment of advanced non-small cell lung cancer(NSCLC). They are both tyrosine kinase inhibitors(TKIs) of the epidermal growth factor receptor(EGFR). In the past decade, there have been reports on clinical benefit from use of erlotinib after gefitinib failure in NSCLC patients. A review of published literature on this focussed topic is provided herein. Pooled analysis of published literature shows that majority of patients were female(60.6%), non-smokers(64.5%), had adenocarcinoma histology(88.3%) and were of East Asian ethnicity(92.3%). Presence of sensitizing EGFR mutation was detected in 48.4% of subjects. Disease control rates with prior gefitinib therapy and with subsequent erlotinib treatment were 79.4% and 45.4% respectively. Based upon our review, the most important predictive factor for clinical benefit from erlotinib identified was previous response to gefitinib. The exact explanations for the potential benefit from erlotinib use in this patient population is still not known and further studies are required to determine the role of molecular mechanismsespecially those related to resistance to initial EGFR TKI therapy. | Navneet Singh Aditya Jindal Digambar Behera | 2014 | World Journal of Clinical Oncology2014，5，5： | 5 |
| 4 | An updated review on activated PI3 kinase delta syndrome(APDS)显示文摘Activated Phosphoinositide 3-kinase d syndrome(APDS)is a newly recognised primary immunodeficiency disease.It has currently been a hot topic of clinical research and new data are emerging regarding its pathogenesis,clinical manifestations and treatment.Patients with APDS syndrome have significant autoimmune manifestations and lymphoproliferation.It is important to differentiate APDS from the usual polygenic CVID in view of the availability of targeted therapy like mTOR inhibitors such as Rapamycin and selective PI3Kd inhibitors.We provide a comprehensive review on this interesting disorder focusing light on its etiology,genetic research and emerging therapy. | Ankita Singh Vibhu Joshi Ankur Kumar Jindal Babu Mathew Amit Rawat | 2020 | Genes & Diseases2020，7，1： | 4 |
| 5 | Recent advances in elucidating the genetics of common variable immunodeficiency显示文摘Common variable immunodeficiency disorders(CVID),a heterogeneous group of inborn errors of immunity,is the most common symptomatic primary immunodeficiency disorder.Patients with CVID have highly variable clinical presentation.With the advent of whole genome sequencing and genome wide association studies(GWAS),there has been a remarkable improvement in understanding the genetics of CVID.This has also helped in understanding the pathogenesis of CVID and has drastically improved the management of these patients.A multiomics approach integrating the DNA sequencing along with RNA sequencing,proteomics,epigenetic and metabolomics profile is the need of the hour to unravel specific CVID associated disease pathways and novel therapeutic targets.In this review,we elaborate various techniques that have helped in understanding the genetics of CVID. | Vaishali Aggarwal Aaqib Zaffar Banday Ankur Kumar Jindal Jhumki Das Amit Rawat | 2020 | Genes & Diseases2020，7，1： | 4 |
| 6 | 云计算中SLA守恒的高效虚拟机迁移方法显示文摘随着在线工作量的激增,云用户呈指数级增长。然而,云环境下需求下单大规模数据中心将导致高能耗。因此,优化资源利用对于提高云数据中心的能效至关重要。现有文献大多关注虚拟机(VM)整合,以简化服务水平协议为代价来提高能效。本文提出了负载感知的三齿轮阈值(LATHR)和改进的最佳拟合减少(MBFD)算法,在提高服务质量的同时,最大限度地降低总能耗。在单个主机上分配的动态工作负载和可变数量的虚拟机(1-290)下,提供了有效结果。实验结果通过SLA、能量消耗、指令能量比(IER)以及相对于不同虚拟机数量的迁移次数来衡量。实验结果表明,与中位数绝对偏差(MAD)、四分位范围(IQR)和双阈值(THR)过载检测策略相比,该技术SLA违反率分别降低了55%、26%和39%,能耗分别降低了17%、12%和6%。 | GARG Vaneet JINDAL Balkrishan | 2021 | Journal of Central South University2021，28，3： | 4 |
| 7 | Shallow foundation response variability due to soil and model parameter uncertainty显示文摘Geotechnical 无常可以与实质的 soil-foundation-structure-interaction (SFSI ) 在结构的反应预言起关键作用效果。自从一个土壤基础的行为,系统可以显著地改变它支持的结构的反应,并且因而,几设计决定,识别并且描绘相关参数是极其重要的。而且,为建模要求的当模特儿的途径和参数为反应预言也是极其重要的。现在的工作打算在在干燥的稠密的沙上休息的浅基础结构系统的反应上调查土壤和模型参数无常的效果。SFSI 用 beam-on-nonlinear-winkler-foundation (BNWF ) 被建模概念在在基础下面的土壤被假定是的地方,分离、非线性的元素的一个集会弹簧,缓冲筒和差距元素创作了。浅基础回答上的土壤和模型输入参数的敏感用一阶的秒时刻(FOSM ) 被调查通过拉丁 hypercube 采样的分析和蒙特卡罗模拟技术。在预言浅基础的回答的精确性的度是高度敏感的土壤参数,这被观察了,例如磨擦角度,泊松比率并且砍模量,而非模型参数,例如僵硬紧张比率和春天间距;为可靠 soilfoundation 反应分析显示土壤参数的合适的描述的重要性。 | Prishati RAYCHOWDHURY Sumit JINDAL | 2014 | Frontiers of Structural and Civil Engineering2014，8，3： | 3 |
| 8 | S-,N-and C-doped ZnO as semiconductor photocatalysts:A review显示文摘In the past few decades,many novel non-metal doped ZnO materials have developed hasty interest due to their adaptable properties such as low recombination rate and high activity under the solar light exposure.In this article,we compiled recent research advances in non-metal(S,N,C)doped ZnO,emphasizing on the related mechanism of catalysis and the effect of non-metals on structural,morphological,optical and photocatalytic characteristics of ZnO.This review will enhance the knowledge about the advancement in ZnO and will help in synthesizing new ZnO-based materials with modified structural and photocatalytic properties. | Vijaya KUMARI Anuj MITTAL Jitender JINDAL Suprabha YADAV Naveen KUMAR | 2019 | Frontiers of Materials Science2019，13，1： | 3 |
| 9 | Leukocyte adhesion defect:Where do we stand circa 2019?显示文摘Migration of polymorphonuclear leukocytes from bloodstream to the site of inflammation is an important event required for surveillance of foreign antigens.This trafficking of leukocytes from bloodstream to the tissue occurs in several distinct steps and involves several adhesion molecules.Defect in adhesion of leukocytes to vascular endothelium affecting their subsequent migration to extravascular space gives rise to a group of rare primary immunodeficiency diseases(PIDs)known as Leukocyte Adhesion Defects(LAD).Till date,four classes of LAD are discovered with LAD I being the most common form.LAD I is caused by loss of function of common chain,cluster of differentiation(CD)18 of β2 integrin family.These patients suffer from life-threatening bacterial infections and in its severe form death usually occurs in childhood without bone marrow transplantation.LAD II results from a general defect in fucose metabolism.These patients suffer from less severe bacterial infections and have growth and mental retardation.Bombay blood group phenotype is also observed in these patients.LAD III is caused by abnormal integrin activation.LAD III patients suffer from severe bacterial and fungal infections.Patients frequently show delayed detachment of umbilical cord,impaired wound healing and increased tendency to bleed.LAD IV is the most recently described class.It is caused by defects in β2 and α4β1 integrins which impairs lymphocyte adhesion.LAD IV patients have monogenic defect in cystic-fibrosis-transmembraneconductance-regulator(CFTR)gene,resulting in cystic fibrosis.Pathophysiology and genetic etiology of all LAD syndromes are discussed in detail in this paper. | Jhumki Das Avinash Sharma Ankur Jindal Vaishali Aggarwal Amit Rawat | 2020 | Genes & Diseases2020，7，1： | 2 |
| 10 | onunion of paediatric talar neck fracture显示文摘儿科学的距骨的破裂在治疗期间是由 posttraumatic 关节和 avascular 坏死很复杂的很少发生的损害。在孩子不属于工会以前没在文学被报导。我们报导有的一个 12 岁的男孩的一个案例一 talar 的霍金斯类型 II 骨折不属于工会颈。不属于工会与好临床的结果通过手术被对待。管理在的目标儿科学的 talar 颈骨折不属于工会与在新鲜破裂的那些不同。没有试试可以引起进一步的缺陷的一个激进的手术,非最优的减小应该是可接受的。 | Nipun Jindal Parmanand Gupta Sandeep Jindal | 2014 | Chinese Journal of Traumatology2014，17，1： | 2 |
| 11 | Management of acute hepatitis B and reactivation of hepatitis B显示文摘 | Ankur Jindal Manoj Kumar Shiv K. Sarin | 2013 | Liver Int2013，，： | 2 |
| 12 | Effect of vesicular-arbuscular mycorrhizae on metabolism of moong plants under NaCl salinity 显示文摘 | Jindal V Atwal A Sekson B S | 1993 | Plant Physiol Biochem1993，31，： | 1 |
| 13 | Adhesion measurements of chemically vapor deposited and physical vapor deposited hard coating on WC-CO substrate显示文摘 | Jindal P C | 1987 | Thin Slid Film1987，，154： | 1 |
| 14 | Prevalence of diabetic nephropathy in an underserved rural community显示文摘 | Jindal RM Salifu MO Patel TG | 2012 | Indian J Nephrol2012，22，6： | 1 |
| 15 | Ultrasound guided percutaneous nephrostomy for obstructive uropathy in benign and malignant diseases显示文摘 | Sood G Sood A Jindal A | 2006 | Int Braz J Urol2006，32，3： | 1 |
| 16 | New directions for induction immunosuppresaion strategy in solid organ transplantation显示文摘 | Hawksworth JS Leeser D Jindal RM | | 0，，04： | 1 |
| 17 | Diagnosis and management of congenital adrenal hyperplasia in the child and adolescent显示文摘 | Kochar IP Jindal R | | 0，，04： | 1 |
| 18 | Adhesion Measurements of Chemically Vapor Deposited and Physically Vapor Deposited Hard Coatings on WC-Co Substrates 显示文摘 | Prem C Jindal Dennis T Quinto and George J Wolfe | 1987 | Thin Solid Films1987，154，： | 1 |
| 19 | Ca- pacity Limits of MIMO Channels显示文摘 | GOLDSMITH A JAFAR S JINDAL N et at | 2003 | IEEE Jour- nal on Selected Areas in Communications2003，21，5： | 1 |
| 20 | Protective role of IL-18- 137G/C polymorphism in a North Indian population with asthma: a pilot study显示文摘 | Birbian N Singh J Jindal SK | 2013 | Cytokine2013，61，1： | 1 |
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