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| 1 | Antifungal activity of Aegle marmelos(L.) Correa(Rutaceae) leaf extract on dermatophytes显示文摘Objective:To evaluate the in vitro antifungal activity of Aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like Trichophyton mentagrophytes,Trichophyton rubrum,Microsporum canis,Microsporum gypseum and Epidermophyton floccosum.Methods:The minimum inhibitory concentration(MIC) and minimum fungicidal concentration(MFC) of various extracts and fractions of the leaves of Aegle marmelos were measured using method of National Committee for Clinical Laboratory Standards(NCCLS).Results:Aegle marmelos leaf extracts and fractions were found to have fungicidal activity against various clinical isolates of dermatophytic fungi.The MIC and MFC was found to be high in water and ethyl alcohol extracts and methanol fractions(200μg/mL) against dermatophytic fungi studied.Conclusions:Aegle marmelos leaf extracts significantly inhibites the growth of all dermatophytic fungi studied.If this activity is confirmed by in vivo studies and if the compound is isolated and identified,it could be a remedy for dermatophytosis. | Balakumar S Rajan S Thirunalasundari T Jeeva S | 2011 | Asian Pacific Journal of Tropical Biomedicine2011,1,4: | 8 |
| 2 | Antibacterial activity of selected ethnomedicinal plants from South India显示文摘Objective:To screen the antimicrobial potential of three ethnomedicinal plants Chassalia curviflora Thw.(C.curviflora),Cyclea peltata Hook.F.& Thomson(C.peltata) and Euphorbia hirta L(E.hirta) used in folk medicines in Aarukani hills Kani tribe,Tamil Nadu,India against human bacterial pathogens.Methods:Antibacterial efficacy was performed by disc diffusion method against the pathogens viz.,Escherichia coli(E.coli)(ATCC 35218),Staphylococcus aureus (S.aureus)(ATCC 6538),Salmonella typhi(S.typhi)(MTCC 733),Proteus vulgaris(P.vulgaris), Proteus mirabilis(P.mirabilis) and Streptococcus pyogenes(S.pyogenes) and incubated for 24 h at 37°C.Results:The maximum degree of antibacterial activity was observed in C.peltata followed by C.curviflora.While E.hirta showed comparatively low degree of antibacterial activity.The methanolic extract of C.peltata showed the antibacterial activity against three pathogens viz.,S.pyogenes,P.vulgaris and E.coli with the inhibition zones 12 mm,10 mm and 9 mm,respectively,hexane extracts of C.peltata also showed the antibacterial activity against two selected pathogens viz.,P.vulgaris and P.mirabilis with 15 mm and 12 mm of inhibition zones.All the three different concentrations(025,0.50 & 0.75 mg/mL) of methanolic extract of C. peltata show the inhibitory effect on the three susceptible bacteria S.pyogenes,P.vulgaris and E. coli with the maximum inhibition in the highest concentration(0.75 mg/mL).The methanolic and hexane extracts of C.curviflora exhibited the antibacterial activity against only one bacterium each i.e.P.vulgaris and S.typhi with the maximum zone of inhibition 13 and 11 mm respectively. The methanolic and hexane extracts of E.hirta exhibited the antibacterial activity against only one bacterium Le.S.pyogenes with the maximum zone of inhibition 13 and 11 mm respectively. Conclusions:The present investigation revealed that the C.curviflora,C.peltata and E.hirta are potentially good source of antibacterial agents and demonstrates the importance of such plants in traditional medicines. | Rajendran Darling Anpin Raja Solomon Jeeva Juststella Wilfred Prakash Johnson Marimuthu Antonisamy Varaprasadham Irudayaraj | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,5: | 6 |
| 3 | Phytochemical constituents and antibacterial efficacy of the flowers of Peltophomm pterocarpum(DC.) Baker ex Heyne显示文摘Objective:To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum pterocarpum.Methods:Phytochemical analysis was done by using the standard methods given by Harbone.The methanolic flower extract were tested against Escherichia coli,Klebsiella pneumonia,Pseudomonas aeruginosa.Staphylococcus aureus. Bacillus cereus,Salmonella typhi,Serratia marsecens,Acinetobacter baumannii.Enterobacter sp., Proteus mirabilis.Enterococcus faecalis and Streptococcus pyogenes by the agar disc diffusion method.Results:Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds,flavonoids.saponins,steroids,tannins,xanthoproteic,carboxylic acids, coumarins and carbohydrates.The flower extract of Peltophorum pteroearpum showed significant activity against four gram positive(Staphylococcus aureus.Bacillus cereus.Enlerococcus faecalis and Streptococcus pyogenes) and three gram negative bacteria(Proteus mirabilis,Acinetohacter baumannii and Serratia marsecens).out of 12 pathogenic bacteria studied.Conclusion:The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pleracarpum. | Sukumaran S Kiruba S Mahesh M Nisha SR Miller Paul Z Ben CP Jeeva S | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,9: | 4 |
| 4 | Antifungal activity of Ocimum sanctum Linn.(Lamiaceae) on clinically isolated dermatophytic fungi显示文摘Objective:To assess antifungal activity of Ocimum sanctum leaves against dermatophytic fungi. Methods:Antifungal activity of Ocimum sanctum leaves was measured by 38 A NCCLS method. Minimum inhibitory concentration(MIC) and minimum fungicidal concentration(MFC) of various extracts and fractions of Ocimum sanctum leaves were also determined.Results:Ocimum sanctum leaves possessed antifungal activity against clinically isolated dermatophytes at the concentration of 200μg/mL.MIC and MFC were high with water fraction(200μg/mL) against dermatophytic fungi used.Conclusions:Ocimum sanctum has antifungal activity,and the leaf extracts may be a useful source for dermatophytic infections. | Balakumar S Rajan S Thirunalasundari T Jeeva S | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,8: | 3 |
| 5 | Anti-bacterial studies on Hemigraphis colorata(Blume) H.G.Hallier and Elephantopus scaber L.显示文摘Objective:To examine the ethanol,aqueous,chloroform,benzene,acetone and petroleum ether extracts of Hemigraphis colorata(H.colorata) leaves and stem and Elephantopus scaber (E.scaber) leaves,root and flower for the presence of phyto-constituents and screened the antibacterial activity against the selected pathogens.Methods:The fresh materials were shade dried and powdered using the tissue blender.The dried and powered materials(50 g) were extracted successively with 200 mL of aqueous,acetone,benzene,chloroform,etganol.and petroleum ether by using Soxhlet extractor for 8 h at a temperature not exceeding the boiling point of the solvent.Aqueous,acetone,benzene,chloroform,ethanol.and petroleum ether extracts were prepared from powdered materials were used for preliminary phytnehemical and antimicrobial studies using standard methods.Results:The crude aqueous,acetone,benzene,chloroform, ethauol.and petroleum ether extracts E.scaber leaves,flower and root and H.colorata leaves and stem demonstrated that out of(5×6×12 = 360) tests for the presence or absence of the above compounds.188 tests gave positive results and the remaining 172 gave negative results. The results of the phvtochemical screening revealed that phenol(12/12).carbohydrates(9/12). steroids(8/12).saponins and coumarins(7/12).tannins(6/12),proteins(5/12).earboxylic acid and flavonoids(4/12).xanthoproteins(3/12) and alkaloids(2/12) presence in the crude aqueous, acetone,benzene,chloroform,ethanol.and petroleum ether extracts of H.colorata leaves and stem.The crude aqueous,acetone,benzene,chloroform,ethanol.and petroleum ether extracts E.scaber leaves,flower and root displayed the presence of phenol(18/18).tannin(17/18). carbohydrates(16/18).steroids(14/18),oarboxylic acid and coumarins(12/18).saponins(10/18), xanthoprotein(9/18).flavonoids(7/18).protein(4/18) and alkaloids(2/18).The root ethanolic extracts of E.scaber illustrated the highest zone of inhibition against three pathogens viz.. Staphylococcus aureus(S.aureus)(24 mm).Escherichia coli(E.coli)(16 mm) and Psemlomonas aeruginosa {P.aeruginosa)(13 mm).The chlorofrom extracts of E.scaber showed the highest zone of inhibition against Bacillus cereus(B.ceretus)(12 mm).The leaves ethanolic extracts of E.scaber demonstrated the highest zone of inhibition against three pathogens viz.,Enterococcus faecalis (E.faecalis)(18 mm).Proteus mirabilis(P.mirabilis)(17 mm).Salmonella Typhi(S.typhi)(14 mm) and Enterobacter sp.(11 mm) While the benzene extracts of H.colorata demonstrated maximum zone of inhibition against the pathogen Acinetobucter sp.(14 mm) and S.aureus (12 mm).Conclusions:It is hoped that this study would direct to the establishment of some compounds that could be used to invent new and more potent antimicrobial drugs of natural origin. | Vimala Thankappan Anitha Johnson Marimuthu Solomon Jeeva | 2012 | Asian Pacific Journal of Tropical Medicine2012,5,1: | 2 |
| 6 | Performance characteristics of corrosion resistant black coatings 显示文摘 | JEEVA P A KARTHIKEYAN S NARAYANAN S | 2013 | Procedia Engineering2013,64,: | 1 |
| 7 | Cytokinin induced shoot regeneration and flowering of Scoparia dulcis L.(Scrophulariaceae)-an ethnomedicinal herb显示文摘Objective:To develop an improved protocol for micropropagation of ethnomedicinally important Scoparia dulcis(S.dulcis) L.Methods:Explants were inoculated on MS basal medium supplemented with kinelin and 6-benzylaminopurine for shoot bud induction.To enhance the shoot induction,various auxins like 3-indoleacetic acid or 3-indolebutyric acid or a-naphthylacetic acid were tested along with 2.32 M KI and 4.44 μ M BAP.The regenerated shoots were rooted in half strength MS medium supplemented with various concentrations of IAA,IBA or NAA.After roots were developed,the plantlets were transplanted to pots filled with vermiculate and sand and kept in growth chamber with 70%-80%humidity under 16 h photoperiod.After acclimatization,the plantlets were transferred to the garden and survival percentage was calculated.Data were statistically analyzed and means were compared using Duncan's multiple range test(P<0.05).Results:An in vitro method was developed to induce high frequency shoots regeneration from stem,mature leaf and young leaf explants of S.dulcis.Shoot induction on young leaf explants was most successful in MS medium supplemented with combination of two cytokinins(2.32 μ M KI and 4.44 μ M BAP) 2.85 μ M IAA,10%CM and 1 483.79 μM adenine sulfate.A single young leaf explant was capable of producing 59 shoots after 13 days of culture. Flower was induced in medium supplemented with combination of KI and BAP.Conclusions: Cytokinins are the key factor to induce the direct shoot regeneration and flowering of S.dulcis. | Premkumar G Sankaranarayanan R Jeeva S Rajarathinam K | 2011 | Asian Pacific Journal of Tropical Biomedicine2011,1,3: | 1 |
| 8 | Cortical/hippocampal monoamines, HPA-axis changes and aversive behavior following stress and restress in an animal model of post-traumatic stress disorder显示文摘 | Harvey BH Brand L Jeeva Z | 2006 | Physiol Behav2006,87,5: | 1 |
| 9 | Facile fabrication of core-shell Pr6Oli-ZnO modified silane coatings for anti-corrosion applica- tions显示文摘 | Jeeva Jothi K Palanivelu K | 2014 | Applied Surface Science2014,288,: | 1 |
| 10 | The species richness and composition of termites (Isoptera) in primary and regenerating lowland dipterocarp forest in Sabah, East Malaysia显示文摘 | Eggleton P Homathevi R Jeeva D | 1997 | Ecotropica1997,3,2: | 1 |
| 11 | The effect of hyperoxygenation on T1 relaxation time in vitro 1显示文摘 | Bertrand Janne d’Othée Guy Rachmuth Jeeva Munasinghe Elvira V Lang | 2003 | Academic Radiology2003,,: | 1 |
| 12 | Survey on background modeling and foreground detection for real time video sur- veillance 显示文摘 | Jeeva S Sivabalakrishnan M | 2015 | Procedia Computer Science2015,50,: | 1 |
| 13 | Cortical/hippocampal monoamines,HPA-axis changes and aversive behavior following stress and restress in an animal model of post-traumatic stress disorder显示文摘 | Harvey BH Brand L Jeeva Z | 2006 | Physiol Behav2006,87,5: | 1 |
| 14 | Short-term outcomes of acute fulminant myocarditis in children显示文摘 | Sankar J Khalil S Jeeva Sankar M | 2011 | Pediatr Cardiol2011,32,7: | 1 |
| 15 | Hypocalcemia in the Newborn显示文摘 | Jain A Agarwal R Jeeva SM | 2010 | Indian J Pediatr2010,77,10: | 1 |
| 16 | Selective Oxidation of p-Methoxybenzaidehyde over V2O5/CaO-MgO Catalysts显示文摘 | Reddy B M Vijaya K M Jeeva R K | 1999 | Appl Catal A1999,181,: | 1 |
| 17 | Hypoglycemia in the newborn 显示文摘 | Jain A Aggarwal R Jeeva Sankar M | 2010 | Indian J Pediatr2010,77,10: | 1 |
| 18 | Hypoglycemia in the newborn显示文摘 | Jain A Aggarwal R Jeeva Sankar M | 2010 | lndian J Pediatr2010,77,10: | 1 |
| 19 | Short-term out- comes of acute {ulminant myocarditis in ehildren显示文摘 | Sankar J Khalil S Jeeva Sankar M | 2010 | Pediatr Cardiol2010,32,7: | 1 |
| 20 | Preliminary phytochemical studies on the methanolic flower extracts of some selected medicinal plants from India显示文摘 | Antonisamy J M Aparna J S Jeeva S | 2012 | Asian Pacific J Tropical Biomed2012,2,1: | 1 |