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	题名	作者	年代	出处	被引量
1	Folic acid supplementation inhibits recurrence of colorectal adenomas:A randomized chemoprevention trial显示文摘AIM: To determine whether folic acid supplementation will reduce the recurrence of colorectal adenomas, the precursors of colorectal cancer, we performed a double-blind placebo-controlled trial in patients with adenomatous polyps. METHODS: In the current double-blind, placebo-controlled trial at this VA Medical Center, patients with colorectal adenomas were randomly assigned to receive either a daily 5 mg dose of folic acid or a matched identical placebo for 3 years. All polyps were removed at baseline colonoscopy and each patient had a follow up colonoscopy at 3 years. The primary endpoint was a reduction in the number of recurrent adenomas at 3 years. RESULTS: Of 137 subjects, who were eligible after confirmation of polyp histology and run-in period to conform compliance, 94 completed the study; 49 in folic acid group and 45 in placebo group. Recurrence of adenomas at 3-year was compared between the two groups. The mean number of recurrent polyps at 3-year was 0.36 (SD, 0.69) for folic acid treated patients compared to 0.82 (SD, 1.17) for placebo treated subjects, resulting in a 3-fold increase in polyp recurrence in the placebo group. Patients below 70 years of age and those with left-sided colonicadenomas or advanced adenomas responded better to folic acid supplementation. CONCLUSION: High dose folic acid supplementation is associated with a signif icant reduction in the recurrence of colonic adenomas suggesting that folic acid may be an effective chemopreventive agent for colorectal neoplasia.	Richard Jaszewski Sabeena Misra Martin Tobi Nadeem Ullah Jo Ann Naumoff Omer Kucuk Edi Levi Bradley N Axelrod Bhaumik B Patel Adhip PN Majumdar	2008	World Journal of Gastroenterology2008，14，28：	10
2	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar AP	2001	Anticancer Res2001，21，：	1
3	Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirs显示文摘	Xue S Jaszewski A Perlman S	1995	J Virol1995，208，1：	1
4	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar AP	2001	Anticancer res2001，21，2：	1
5	Curcumin induced modulation of cellcycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar AP	2001	Anticancer Res2001，21，2：	1
6	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	MORAGODA L JASZEWSKI R MAJUMDAR A P	2001	Anticancer Res2001，21，：	1
7	Curcumin in- duced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar HP	2011	Hnticancer Res2011，21，2：	1
8	Mycotic DNA in non-atherosclerotic aortic wall of coronary patients is associated with sICAM-1 expression显示文摘	Jeqier B Jaszewski R Kurnatowski P		0，，04：	1
9	Hot embossing in polymers as a direct way to pattern resist 显示文摘	Jaszewski R W Schift H Gobrecht J Smith P	1998	Microelectronic Engineering1998，4142，：	1
10	Hot embossing in polymers as a direct way to pattern resist 显示文摘	JASZEWSKI R W SCHIFT H GOBRECHT J	1998	Microelectron Eng1998，41，：	1
11	Hot embossing in polymers as a direct way to pattern resist显示文摘	Schift H Gobrecht J	1998	Microelectronic Engineering1998，4142，：	1
12	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar AP	2001	Anticancer Res2001，21，2：	1
13	Neutrophil chemotaxis in gastric mucosa A signal-to-response comparison显示文摘	Kozol R Domanowski A Jaszewski R		0，，：	1
14	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	MORAGODA L JASZEWSKI R MAJUMDAR AP	2001	Anticancer Res2001，21，2：	1
15	Curcumin incedmodulation of cellcycle and apoptosis in gastric andcoloncancer cells显示文摘	Moragoda L Jaszewski R Majumdar A P	2001	Anticancer Research2001，21，2：	1
16	Curcumin in ducedmodulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Jaszewski r Majumdar ap	2001	Anticancer Res2001，21，2：	1
17	Giant duodenal ulcers显示文摘	Richard Jaszewski MD Steven A. Crane MD Arturo A. Cid MD	1983	Digestive Diseases and Sciences1983，，6：	1
18	Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells显示文摘	Moragoda L Jaszewski R Majumdar AP	2001	Anticancer Res2001，21，2：	1
19	Aging enhance G(1) phase in the colonic muceosa of rats显示文摘	Xiao ZQ Jaszewski R Majumdar AP	2000	Mech Ageing Dev2000，116，1：	1
20	Tricuspid valve annuloplasty: early and long-term (13 years follow-up: 1988- 2001)显示文摘	Kosmider A Zaslonka J Jaszewski R	2004	Acta Cardiol2004，59，2：	1

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