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| 1 | 地铁施工引起的建筑物扭曲变形分析显示文摘隧道施工或深基坑开挖过程中会引起地面建筑物或其他结构产生复杂的变形,长期以来,对建筑物的弯曲或剪切变形都进行过一些研究,但是一般都忽略了结构的扭曲变形。事实上,由于地层的位移,会引起附近的各类结构普遍承受不同程度的扭曲变形。本文讨论了建筑物某一个平面的扭曲变形(例如基础平面,或建筑物的某一个立面)问题。首先给出了一个平面扭曲变形的数学定义,然后基于力学分析和受力推导,得到了平面变形扭曲的量化表征和计算方法。进一步在对实测资料分析的基础上,探讨在某些简化假定条件下,建筑物基础板的扭曲变形分析方法。最后以伦敦伊丽莎白大厦(E lizabeth House)为例,采用本文所提出的方法具体量化分析了该建筑物在地铁隧道施工过程中产生的扭曲变形,并对扭曲变形的规律进行了探讨,对扭曲变形对结构安全的影响进行了分析。 | 韩煊 Jamie R Standing 李宁 | 2010 | 土木工程学报2010,43,1: | 19 |
| 2 | Residual renal function in peritoneal dialysis with failed allograft and minimum immunosuppression显示文摘Immunosuppression(IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function(RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis(PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation. Hemodialysis was initiated via tunneled dialysis catheter(TDC) and IS was gradually withdrawn. Two weeksafter IS withdrawal he developed a febrile illness, which necessitate removal of the TDC and conversion to PD. He was maintained on small dose of tacrolimus(1 mg/d) and prednisone(5 mg/d). Currently(1 year later) he is doing exceedingly well on cycler-assisted PD. Residual urine output ranges between 600-1200 m L/d. Total weekly Kt/V achieved 1.82. RRF remained well preserved in this patient with failed renal allograft with minimal immunosuppressive therapy. This strategy will need further study in well-defined cohorts of PD patients with failed allografts and residual RRF to determine efficacy and safety. | Nadear Elmahi éva Csongrádi Kenneth Kokko Jack R Lewin Jamie Davison Tibor Fülp | 2013 | World Journal of Transplantation2013,3,2: | 5 |
| 3 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013,19,48: | 4 |
| 4 | 多重结局的多元Meta分析和多重治疗的网状Meta分析:原理、概念及实例显示文摘英国国家健康与临床优选研究所(NICE)等组织需要对现有研究获得的证据进行整合来指导决策,需要确定关于多重疗效及安全性结局的最佳治疗。但是,相关的研究不一定对所有关注的治疗或结局都进行了直接比较,多元Meta分析及网状Meta分析为如何确定最佳治疗这一问题提供了思路,该方法不仅考虑了直接证据,还利用了关联或间接的证据。本文中,研究者描述了这些方法学的重要概念及假设,并阐述关联及间接证据如何产生,同时通过图表说明这些证据在涉及多重结局和多重治疗的真实临床案例中如何使用。 | Richard D Riley Dan Jackson Georgia Salanti Danielle L Burke Malcolm Price Jamie Kirkham Ian R White 孙至佳(译) 张岩(译) 刘雪晴(译) 杨智荣(校) 孙凤(校) | 2018 | 英国医学杂志中文版2018,21,12: | 2 |
| 5 | Characterization of a unique ethanologenic yeast capableof fermenting galactose显示文摘 | Jamie R Rodney J Bothast John N S Shawn D M | 2004 | Enzyme and Microbial Technology2004,35,: | 1 |
| 6 | Sealing Pond bottoms with muddy water显示文摘 | Herman B Jamie L Robert C R | 2001 | Ecological Engineering2001,18,2: | 1 |
| 7 | Polymer replicas of photonic porous silicon for sensing and drug delivery applications 显示文摘 | Li Y Y Cunin F Jamie R | 2003 | Science2003,299,5615: | 1 |
| 8 | Covalent anchoring of copper-Schiff base complex into SBA-15 as a het- erogeneous catalyst for the synthesis of pyridopyrazine and qui- noxaline derivatives 显示文摘 | BARDAJEE G R MALAKOOTI R JAMI F | 2012 | Catalysis Communications2012,27,: | 1 |
| 9 | Biosynthesis of dichloroimines in the tropical marine sponge Stylotella aurantium显示文摘 | Jamie SS Parul R Mary JG | 1997 | Tetrahedron Letter1997,38,45: | 1 |
| 10 | Wear behaviour of interpenetrating alumina–copper composites显示文摘 | Jami Winzer Ludwig Weiler Jeanne Pouquet Jürgen R?del | 2011 | Wear2011,,11: | 1 |
| 11 | Methane emission from free-ranging sheep:a comparison of two measurement methods显示文摘 | Leuning R Baker S K Jamie I M | 1999 | Atmospheric Environment1999,33,9: | 1 |
| 12 | Bovine lactoferricincauses apoptosis in Jurkat T-leukemia cells by sequentialpermeabilization of the cell membrane and targeting of mito-chondria显示文摘 | Jamie SM Angela R Jayme S | 2007 | Experimental Cell Research2007,313,: | 1 |
| 13 | Biosynthesis of dichloroimines in the tropical marine sponge Stylotella aurantium 显示文摘 | Jamie SS Parul R Mary JG | 1997 | Tetrahedron Lett1997,38,45: | 1 |
| 14 | A longitudinal study of relational and physical aggression in preschool 显示文摘 | Crick N R Jamie M Ostrov Jean E | 2006 | Applied Developmental Psychology2006,27,: | 1 |
| 15 | 早期乳腺癌最佳辅助化疗方案与人类表皮生长因子受体2阳性乳腺癌辅助靶向治疗选择:依据 ASCO 对 CCO临床实践指南的改编显示文摘目的研究加拿大安大略癌症治疗中心(CCO)关于早期乳腺癌最佳辅助化疗方案,包括人类表皮生长因子受体2(HER2)阳性乳腺癌辅助靶向治疗方案,并对其进行改编。方法按照美国临床肿瘤协会(ASCO)对其他组织临床实践指南改编的策略和程序,对CCO临床实践指南的严谨性与内容适用性进行回顾。结果基于对CCO临床实践指南内容的回顾,ASCO小组认为,CCO临床实践指南在整体上清晰全面,以最确切的科学证据为基础,为患者提供可接受的治疗选项。推荐关于辅助化疗方案的决定,应考虑到基线复发风险、毒性、利益可能性和宿主因素(如合并症)。对于高风险HER2阴性的身体状况良好的人群,蒽环类和紫杉烷治疗方案是标准治疗方案。4个周期的多西他赛和环磷酰胺治疗方案是可接受的非蒽环类治疗方案。对于高风险HER2阳性患者,推荐蒽环类与紫杉烷序贯疗法联合曲妥单抗或多西他赛、卡铂、曲妥单抗进行6个周期的治疗。对于低风险、非淋巴结转移、HER2阳性人群,推荐每周一次的紫杉醇和曲妥单抗连续进行12个周期的替代治疗。曲妥单抗应持续使用1年。不应采用铂复合盐对三阴性人群进行常规的辅助管理,除非出现有效的生存数据加以支持。 | Neelima Denduluri Mark R Somerfield Andrea Eisen Jamie N Holloway Arti Hurria Tari A King Gary H Lyman Ann H Partridge Melinda L Telli Maureen E Trudeau Antonio C Wolff 本刊编辑部 | 2016 | 中国全科医学2016,19,18: | 1 |
| 16 | Relationship between self - efficacy and physical activity among patients with type 2 diabetes显示文摘 | Gareth R Bridgette C Jamie L | 2009 | Behavior Med )2009,32,: | 1 |
| 17 | Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF_therapy显示文摘 | Jamie G E Animesh S | 2004 | J Exp Med2004,200,3: | 1 |
| 18 | The ecotoxicology and chemistry of manufactured nanoparticles显示文摘 | Richard D Handy yon der Kammer Frank Jamie R Lead | 2008 | Ecotoxicology2008,17,: | 1 |
| 19 | Isolation of tetranuclear orgunoantimony oxo clusters and hexa-decanuclear polyoxostibonates 显示文摘 | JAMI A K PRABHU M S R BASKAR V | 2010 | Organometallics2010,29,5: | 1 |
| 20 | Diabetes,glucose toxicity, and oxidative stress: A case of double jeopardy for the pancre atic islet β cell显示文摘 | R Paul Robertson Jamie S Harmon | 2006 | Free Radical Biology & Medicine2006,41,5: | 1 |