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| 1 | Pediatric functional constipation treatment with Bifi dobacterium-containing yogurt:A crossover,double-blind,controlled trial显示文摘AIM: To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS: A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, according to Roma Ⅲ criteria. The students were randomized in two groups to receive a goat yogurt supplemented with 109 colony forming unit/mL Bifidobacterium longum (B.longum) (probiotic) daily or only the yogurt for a period of 5 wk (formula). Afterwards, the groups were intercrossed for another 5 wk. Defecation frequency, stool consistency and abdominal and defecation pain were assessed.RESULTS: Both treatment groups demonstrated improvement in defecation frequency compared to baseline. However, the group treated with probiotic showed most signif icant improvement in the f irst phase of the study. An inversion was observed after crossing over, resulting in a reduction in stool frequency when this group was treated by formula. Probiotic and formula improved stool consistency in the f irst phase of treatment, but the improvement obtained with probiotic was significantly higher (P = 0.03). In the second phase of treatment, the group initially treated with probiotic showed worseningstool consistency when using formula. However, the difference was not signif icant. A signif icant improvement in abdominal pain and defecation pain was observed with both probiotic and formula in the first phase of treatment, but again the improvement was more signif icant for the group treated with B. longum during phase I (P < 0.05). When all data of the crossover study were analyzed, significant differences were observed between probiotic yogurt and yogurt only for defecation frequency (P = 0.012), defecation pain (P = 0.046) and abdominal pain (P = 0.015). | Paula VP Guerra Luiza N Lima Tassia C Souza Vanessa Mazochi Francisco J Penna Andreia M Silva Jacques R Nicoli Elizabet V Guimares | 2011 | World Journal of Gastroenterology2011，17，34： | 25 |
| 2 | A combined analysis of the cystic fibrosis transmembrane conductance regulator: implications for structure and diease models显示文摘 | Chen J M Cutler C Jacques C | 2001 | Mol Biol Evol2001，18，9： | 2 |
| 3 | Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3kinase/Akt and GluT-4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats显示文摘 | Tremblay F Lavigne C Jacques H | 2003 | Diabetes2003，52，1： | 1 |
| 4 | Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the venestent study 显示文摘 | Hanekamp C E E Jacques J K den Heijer P | 2003 | Catheter Cardiovasc Interv2003，60，： | 1 |
| 5 | Microelectrode guided posteroventral medial radiofrequency pallidotomy for Parkinson's disease显示文摘 | KOPYOV O JACQUES D DUMA C | 1997 | J Neurosurg1997，87，： | 1 |
| 6 | Use of the 3,H2AX assay for assessing the genotoxicity of polycyclic aromatic hydro- carbons in human cell lines显示文摘 | AUDEBERT M RIU A JACQUES C | 2010 | Toxicol Lett2010，199，2： | 1 |
| 7 | Proinflammatory ac- tions of visfatin/nicotinamide phosphoribosyhransferase (Nampt) in- volve regu-lation of insulin signaling pathway and Nampt enzymatic ac- tivity显示文摘 | Jacques C Holzenberger M Mladenovic Z | 2012 | J Biol Chem2012，287，15： | 1 |
| 8 | The role of IL - 1 and IL -1Ra in joint inflammation and cartilage degradation 显示文摘 | Jacques C Gosset M Berenbaum F | 2006 | Vitam Horm2006，74，： | 1 |
| 9 | Immunocytochemical characterization of pulmonary histiocytosis X cells in lung biopsies显示文摘 | Soler P Chollet S Jacque C | 1985 | Am J Pathol1985，118，3： | 1 |
| 10 | Background Subtraction and Shadow Detection in Grayscale Video Se- quences 显示文摘 | Jacques J C S Jung C R Raupp Musse S | 2005 | Computer Graphics and Image Processing2005，1，1： | 1 |
| 11 | Exact method for robotic cell problem 显示文摘 | Mohamed K Jacques C Mohamed H | 2011 | Flexible Services and Manufacturing Journal2011，23，2： | 1 |
| 12 | Hydrolysis of p-nitrophenyl pal- mitate in n-heptane by the Pseudomonas cepacia lipase: A simple test for the determination of lipase activity in organic media 显示文摘 | GAELLE P JACQUES C B | 1996 | Enzyme &Microbial Technology1996，18，6： | 1 |
| 13 | The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation显示文摘 | Cosset M Berenbaum F | 2006 | Vitam Horm2006，74，： | 1 |
| 14 | Airborne lidar measuments of aerosol spatial distribution and optical properties over the Atlantic Ocean during a European pollution outbreak of ACE-2显示文摘 | Jacques P Partrick C | 2000 | Tellus B2000，52，2： | 1 |
| 15 | Cryopreservation of boar semen and its future importance to the industry 显示文摘 | Bailey J L Lessard C Jacques J | 2008 | Theriogenology2008，70，： | 1 |
| 16 | The effect of mycophenolate mofetil on hepatitis B viral load in stable renal transplant recipients with chronic hepatitis B显示文摘 | Maes Bart D Jacques C | 2001 | Transplantation2001，72，： | 1 |
| 17 | Characterization of a novel endopolygalacturonase from Aspergillus niger with unique kinetic properties显示文摘 | Lucie Parenicova Harry C M Kester Jacques A E Benen | 2000 | FEBS Letters2000，467，： | 1 |
| 18 | Viable skin efficiently absorbs and metabolizes bisphenol A 显示文摘 | Zalko D Jacques C Duplan H Bruel S Perdu E | 2011 | Chemosphere2011，82，3： | 1 |
| 19 | The role of il-1 and il-1 ra in joint inflammation and cartilage degradation 显示文摘 | Jacques C Gosset M Berenbaum F | 2006 | Vitamins and hormones2006，74，371： | 1 |
| 20 | The role of IL- 1 and IL-1Ra in joint inflammation and cartilage degradation 显示文摘 | Jacques C Gosset M Berenbaum F | 2006 | Vitam Horm2006，74，37： | 1 |
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