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| 1 | New oral pharmacotherapeutic agents for venous thromboprophylaxis after total hip arthroplasty显示文摘Patients undergoing total hip arthroplasty(THA)are at high risk for developing venous thromboembolism and,therefore,require short term prophylaxis with antithrombotic agents.Recently,target specific oral anticoagulants(TSOA)including the direct thrombin inhibitor,dabigatran,and the factorⅩa inhibitors rivaroxaban,apixaban,and edoxaban have been approved for THA thrombopropylaxis in various countries.The TSOAs provide a rapid acting,oral alternative to parenteral agents including low-molecular weight heparins(LMWH)and fondaparinux;and compared to warfarin,they do not require routine laboratory monitoring and possess much fewer drug-drug interactions.Based on phaseⅢclinical studies,TSOAs have established themselvesas an effective and safe option for thromboprophylaxis after THA compared to LMWH,particularly enoxaparin,but require additional evaluation in specific populations such as the renally impaired or elderly.The ability to monitor and reverse these TSOAs in the case of bleeding complications or suspected sub-or supra-therapeutic anticoagulation is of importance,but remains investigational.This review will focus on the drug-specific characteristics,efficacy,safety,and economic impact of the TSOAs for thromboprophylaxis following THA,as well as the aspects of therapeutic monitoring and anticoagulation reversal in the event of bleeding complications or a need for urgent reversal. | Garrett B Aikens Jacob R Osmundson Michael P Rivey | 2014 | World Journal of Orthopedics2014，5，3： | 3 |
| 2 | Interaction of insulin receptor substrate 3 with insulin receptor, insulin receptor-related receptor, insulinlike growth factor-1 receptor, and downstream signaling proteins显示文摘 | Xu P Jacobs A R Taylor S I | 1999 | J Biol Chem1999，274，15： | 1 |
| 3 | Meta-analysis of 143 Reported Cases of Aortic Intramural Hematoma显示文摘 | Maraj R Rerkpattanapipat P Jacobs LE | 2000 | Am J Cardiol2000，86，6： | 1 |
| 4 | Measured context-sensitive half-times of remifentanil and alfentanil 显示文摘 | KAPILA A GLASS P S JACOBS J R | 1995 | Anesthesiology1995，83，5： | 1 |
| 5 | Landscape prospects of the next millennium显示文摘 | JACOBS P MANN R | 2000 | Landscape and Urban Planning2000，，47： | 1 |
| 6 | The Alexander project 1998-2000:susceptibility of pathogens is lated from community acquired respiratory tract infection to commonly used ami microbial agents显示文摘 | Jacobs M R Felm ingham D Appelbaum P C | 2003 | J Antimicrob Chemother2003，52，2： | 1 |
| 7 | Calcifying tendinitis of the rotator cuff: func- tional outcome after arthroseopie treatment 显示文摘 | Jacobs R Debeer P | 2006 | Aeta Orthop Belg2006，3，： | 1 |
| 8 | Submucosal purse-string suture as a treatment of leakage around the indwelling voice prosthesis显示文摘 | JACOBS K DELAERE P R VANDER POORTEN V L | 2008 | Head Neck2008，30，： | 1 |
| 9 | Presence and course of the incisive canal in the human mandibular interforaminal region: two-dimensional imaging versus anatomical observations 显示文摘 | Mraiwa N Jacobs R Moerman P | 2003 | Surg Radiol Anat2003，25，56： | 1 |
| 10 | Percutaneous imaging -guided core breast biopsy:5 years experence in a community hos pital显示文摘 | Margolin F R Leung J W Jacobs R P | 2001 | AmJ Roentgenol2001，177，： | 1 |
| 11 | Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs显示文摘 | HUOGHES M A GLASS P S JACOBS J R | 1992 | Anesthesiology1992，76，3： | 1 |
| 12 | Mapping the literature of nursing:1996-2000显示文摘 | Allen M P Jacobs S K Levy J R | | 0，，02： | 1 |
| 13 | Ultrasonic cleaning of nylon microfiltratio membranes fouled by Kraft paper mill effluent显示文摘 | Li J X Sanderso R D Jacobs E P | | 0，，205： | 1 |
| 14 | Alkylation of isobu- tane with 1-butene on zeolite beta显示文摘 | Loenders R Jacobs P A Martens J A | 1998 | Journal of Catalysis1998，176，： | 1 |
| 15 | Prediction of steady and unsteady loads and hydrodynamic forces on counter-rotating propellers显示文摘 | Tsakonas S Jacobs W R Liao P | 1983 | Journal of Ship Research1983，27，3： | 1 |
| 16 | Non - invasive in Situ Visualisation of Membrane Fouling and Cleaning Processes in Microfiltration by Ultrasonic Signal Reflection 显示文摘 | Li J X Sanderson R D Jacobs E P | 2002 | Water SA2002，28，： | 1 |
| 17 | The influence of the lubricant film on the stiffness and damping characteristics of a deep groove ball bearing显示文摘 | Jacobs W Boonen R Sas P | 2014 | Mechanical Systems and Signal Processing2014，42，12： | 1 |
| 18 | Selective neuronal cell attachment to a covalently patterned monoamine on fluorinated ethylene propylene films显示文摘 | Ranieri J P Bellamkonda R Jacob J | 1993 | Biomed Mater Res1993，27，7： | 1 |
| 19 | Sedimentary ag-gregates in the Peoria Loess of Nebraska,USA显示文摘 | Mason J A Jacobs P M Greene R S B | 2003 | Catena2003，57，： | 1 |
| 20 | PhD Showcase: Haptic-GIS: Exploring the Possibilities显示文摘 | JACOB R MOONEY P CORCORAN P | 2010 | SIGSPATIAL Special2010，3，2： | 1 |
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