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| 1 | Biliary cysts:Etiology,diagnosis and management显示文摘Biliary cysts(BC) are rare dilatations of different parts of a biliary tract.They account for approximately 1% of all benign biliary diseases.BC occur the most frequently in Asian and female populations.They are an important problem for pediatricians,gastroenterologists,radiologists and surgeons.Clinical presentation and management depend on the BC type.Cholangiocarcinoma is the most serious and dangerous BC complication.The other complications associated with BC involve cholelithiasis and hepatolithiasis,cholangitis,acute and chronic pancreatitis,portal hypertension,liver fibrosis and secondary liver cirrhosis and spontaneous cyst perforation.Different BC classifications have been described in the literature.Todani classification dividing BC into five types is the most useful in clinical practice.The early diagnosis and proper treatment are very important,because BC are associated with a risk of carcinogenesis.A malignancy risk increases with the age.Radiological investigations(ultrasonography,computed tomography,endoscopic retrograde cholangiopancreatography and magnetic resonance cholangiopancreatography) play an important role in BC diagnostics.Currently,prenatal diagnosis using ultrasonography is possible.It allows to differentiate biliary disorders in fetals and to perform the early surgical treatment that improves results.In most patients,total cyst excision with Roux-Y hepaticojejunostomy is the treatment of choice.Surgical treat-ment of BC is associated with high success rate and low morbidity and mortality.The early treatment is associated with a lower number of complications.Patients following BC surgery require permanent and careful postoperative observation using laboratory and imaging investigations because of possibility of biliary anastomosis stricture and biliary cancer in tissue remnant. | Beata Jabońska | 2012 | World Journal of Gastroenterology2012，18，35： | 26 |
| 2 | Iatrogenic bile duct injuries:Etiology,diagnosis and management显示文摘Iatrogenic bile duct injuries (IBDI) remain an important problem in gastrointestinal surgery. They are most frequently caused by laparoscopic cholecystectomy which is one of the commonest surgical procedures in the world. The early and proper diagnosis of IBDI is very important for surgeons and gastroenterologists, because unrecognized IBDI lead to serious complications such as biliary cirrhosis, hepatic failure and death. Laboratory and radiological investigations play an important role in the diagnosis of biliary injuries. There are many classifications of IBDI. The most popular and simple classification of IBDI is the Bismuth scale. Endoscopic techniques are recommended for initial treatment of IBDI. When endoscopic treatment is not effective, surgical management is considered. Different surgical reconstructions are performed in patients with IBDI. According to the literature, Roux- en-Y hepaticojejunostomy is the most frequent surgical reconstruction and recommended by most authors. In the opinion of some authors, a more physiological and equally effective type of reconstruction is end- to-end ductal anastomosis. Long term results are the most important in the assessment of the effectiveness of IBDI treatment. There are a few classifications for the long term results in patients treated for IBDI; the Terblanche scale, based on clinical biliary symptoms, is regarded as the most useful classification. Proper diagnosis and treatment of IBDI may avoid many serious complications and improve quality of life. | Beata Jab■ońska Pawe■ Lampe | 2009 | World Journal of Gastroenterology2009，15，33： | 17 |
| 3 | Insulin resistance,adipokine profile and hepatic expression of SOCS-3 gene in chronic hepatitis C显示文摘AIM:to analyze adipokine concentrations,insulin resistance and hepatic expression of suppressor of cytokine signaling 3(SOCS-3)in patients with chronic hepatitis C genotype 1 with normal body weight,glucose and lipid profile.METHODS:The study group consisted of 31 patients with chronic hepatitis C and 9 healthy subjects.Total levels of adiponectin,leptin,resistin,visfatin,omentin,osteopontin and insulin were measured using an ELISA kit.The hepatic expression of SOCS-3 was determined by the use of the reverse transcription polymerase chain reaction method.RESULTS:Homeostasis model assessment for insulin resistance(HOMA-IR)values were significantly higher in hepatitis C virus(HCV)infected patients without metabolic disorders compared to healthy controls(2.24 vs 0.59,P=0.0003).Hepatic steatosis was observed in 32.2%of patients with HCV infection and was found in patients with increased HOMA-IR index(2.81 vs1.99,P=0.05)and reduced adiponectin level(5.96vs 8.37,P=0.04).Inflammatory activity(G≥2)was related to increased osteopontin concentration(34.04vs 23.35,P=0.03).Advanced liver fibrosis(S≥2)was associated with increased levels of omentin and osteopontin(436.94 vs 360.09,P=0.03 and 32.84 vs20.29,P=0.03)and reduced resistin concentration(1.40 vs 1.74,P=0.047).No correlations were reported between adipokine profile,HOMA-IR values and hepatic expression of the SOCS-3 gene.CONCLUSION:We speculated that no relationship between adipokines and HOMA-IR values may indicate that HCV can induce insulin resistance itself.Some adipokines appear to be biochemical markers of steatosis,inflammation and fibrosis in patients with chronic HCV infection. | Kamila Wójcik Elzbieta Jabonowska Aleksandra Omulecka Anna Piekarska | 2014 | World Journal of Gastroenterology2014，20，30： | 8 |
| 4 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 5 | ROR2 gene is associated with risk of non-syndromic cleft palate in an Asian population显示文摘背景受体酷氨酸象kinase一样孤儿受体 2 ( ROR2 )基因最近被显示了在动物模型在腭的开发起重要作用并且居住在连接到的 chromosomal 区域非, syndromic 劈开嘴唇与或没有在学习是调查可能的协会在之间的这的 humans.The 目的劈开腭 ROR2 基因和 non-syndromic 我们测试了的这里的口头的 clefts.Methods 在在 297 non-syndromic 的 ROR2 基因的 38 合格单个核苷酸的多型性( SNP ) | Wang Hong Hetmanski, Jacqueline B. Ruczinski, Ingo Liang, Kung Yee Fallin, M. Daniele Redett, Richard J. Raymond, Gerald V. Chou, Yah-Huei Wu Chen, Philip Kuo-Ting Yeow, Vincent Chong, Samuel S. Cheah, Felicia S. H. Jabs, Ethylin Wang Scott, Alan F. Beaty, Terri H. | 2012 | Chinese Medical Journal2012，，3： | 5 |
| 6 | Pancreatic intraductal papillary mucinous neoplasms:Current diagnosis and management显示文摘Intraductal papillary mucinous neoplasms(IPMNs)represent approximately 1%of all pancreatic neoplasms and 25%of cystic neoplasms.They are divided into three types:main duct-IPMN(MD-IPPMN),branch duct-IPMN(BD-IPMN),and mixed type-IPMN.In this review,diagnostics,including clinical presentation and radiological investigations,were described.Magnetic resonance imaging is the most useful for most IPMNs.Management depends on the type and radiological features of IPMNs.Surgery is recommended for MD-IPMN.For BD-IPMN,management involves surgery or surveillance depending on the tumor size,cyst growth rate,solid components,main duct dilatation,high-grade dysplasia in cytology,the presence of symptoms(jaundice,new-onset diabetes,pancreatitis),and CA 19.9 serum level.The patient’s age and comorbidities should also be taken into consideration.Currently,there are different guidelines regarding the diagnosis and management of IPMNs.In this review,the following guidelines were presented:Sendai International Association of Pancreatology guidelines(2006),American Gastroenterological Association guidelines,revised international consensus Fukuoka guidelines(2012),revised international consensus Fukuoka guidelines(2017),and European evidence-based guidelines according to the European Study Group on Cystic Tumours of the Pancreas(2018).The Verona Evidence-Based Meeting 2020 was also presented and discussed. | Beata Jabłońska PawełSzmigiel Sławomir Mrowiec | 2021 | World Journal of Gastrointestinal Oncology2021，13，12： | 3 |
| 7 | Peripheral blood mononuclear cells acquire myofibroblast characteristics in granulation tissue显示文摘 | Moncada GA Nichols CE | 2005 | J Vasc Res2005，42，2： | 1 |
| 8 | Corneal tyrosine crystals in transient neonatal tyrosinemia 显示文摘 | Driscoll D J Jabs EW Alcorn D | 1988 | J Pediatr1988，113，1： | 1 |
| 9 | Cyclosporine for Ocular Inflammatory Diseases显示文摘 | R. Oktay Ka?maz John H. Kempen Craig Newcomb Ebenezer Daniel Sapna Gangaputra Robert B. Nussenblatt James T. Rosenbaum Eric B. Suhler Jennifer E. Thorne Douglas A. Jabs Grace A. Levy-Clarke C. Stephen Foster | 2010 | Ophthalmology2010，，3： | 1 |
| 10 | Impact of the Liaison Committee of Food and Nutrition on the Quality of Patients' Meals显示文摘 | Yahia Abouda Nabiha Bouafia Mohamed Mahjoub Wadiaa Bannour Riadh Essokri Hanen Zendah Mansour N jab | 2012 | Journal of Life Sciences2012，6，8： | 1 |
| 11 | The kidney as a second site of human C reactive protein formation in vivo 显示文摘 | Jabs WJ Logering BA Gerke P | 2003 | Eur J Immunol2003，33，2： | 1 |
| 12 | High affinity binding of a fungal oligopeptide elicitor to parsley plasma membranes triggers multiple defense responses显示文摘 | Nirnberger T Nennstiel D Jabs T | 1994 | Cell1994，78，3： | 1 |
| 13 | Progression of native coronary plaques and in-stent restenosis are associated and predicted by increased pre-procedural C reactive protein显示文摘 | D Skowasch A Jabs R Andrie | 2005 | Heart2005，91，4： | 1 |
| 14 | Reactive oxygen intermediates as mediators of pro- grammed cell death in plants and animals 显示文摘 | Jabs T | 1999 | Biochem Pharmacol1999，，57： | 1 |
| 15 | Studies of mitotic and centromeric abnormalities in roberts syndrom:Implications for a defect in the mitotic mechanism显示文摘 | Tuck C M Cusano R | 1991 | Chromosoma1991，100，： | 1 |
| 16 | Genomic,cDNA and embryonic expression analysis of zebrafish IRF6,the gene mutated in the human oral clefting disorders Van der Woude and popliteal pterygium syndromes显示文摘 | BEN J JABS E W CHONG S S | 2005 | Gene Expr Patterns2005，5，： | 1 |
| 17 | Human milk improves cognitive and motor development of premature infants during infancy显示文摘 | BIER JAB OLIVER T FERGUSON AE | 2002 | J Hum Lact2002，18，： | 1 |
| 18 | Elicitor stimula- ted ion fluxes and O2 from the oxidative burst are essential components in triggering defense gene activation and phytoa- lexin synthesis in parsley显示文摘 | JABS T TSCHOPE M COLLING C | 1997 | Proc Natl Acad Sci1997，94，： | 1 |
| 19 | Elicitor stimulated ion fluxes and O2-from the oxidative burst are essential components in triggering defense gene ac- tivation and phytoalexin synthesis in parsley 显示文摘 | Jabs T Tschope M Coiling C | 1997 | Proceeding of National Academy of Sciences of the United States of American1997，94，9： | 1 |
| 20 | Transcatheter aortic valve implantation and four-year follow up in a 99-year-old patient 显示文摘 | Jabs A Kilic T Schneile N | 2013 | J Heart Valve Dis2013，22，2： | 1 |
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