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| 1 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010,,10: | 3 |
| 2 | 光动力疗法治疗非小细胞肺癌显示文摘光动力疗法被越来越多地应用于治疗胸部恶性肿瘤。对于早期非小细胞肺癌(如支气管腔内肺癌)、X线检查阴性或同时性原发癌,光动疗法可作为主要治疗手段进行腔内根治性治疗。作为单一根治疗法,光动力疗法是治疗支气管镜可见≤1 cm且无软骨外浸润的肺部肿瘤的最有效方法。对于晚期非小细胞癌患者,光动力治疗可以作为综合根治疗法的一部分,用于减轻阻塞性支气管内病变,增加可手术性或缩小所需手术范围。本文对现有发表的应用光动力疗法治疗至少10例以上非小细胞肺癌病例的研究文献进行综述,提出了光动力疗法应用的治疗建议并进行了总结。 | Charles B Simone II Joseph S Friedberg Eli Glatstein James P Stevenson Daniel H Sterman Stephen M Hahn Keith A Cengel 袁光金 李金銮 朱宇熹 凌扬 | 2013 | 国际病理科学与临床杂志2013,33,3: | 3 |
| 3 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022,13,3: | 2 |
| 4 | Mode of action of the COR15a gene on the freezing tolerance of Arabidopsis thaliana 显示文摘 | STEPONKUS P L UEMURA M JOSEPH R A | 1998 | Proc Nail Acad Sci USA1998,95,14: | 1 |
| 5 | Closed tubular automobile parts demand innovative welding methods 显示文摘 | Michael G P Joseph M L | 1997 | Welding Journal1997,76,10: | 1 |
| 6 | Seismic behavior of composite RCS frame systems显示文摘 | Miehael N Bugeja Joseph M Bracci Walter P MooreJr | 2000 | Joumal of Structural Engineering2000,126,4: | 1 |
| 7 | Cold Acclimation of Arabidopsis Thalian 显示文摘 | M Uemura R A Joseph and P L Steponkus | 1995 | Plant Physiol1995,,109: | 1 |
| 8 | Virtual Corporations: Recipe for Success 显示文摘 | P M Joseph R R Levary | 1998 | Industrial Management1998,40,4: | 1 |
| 9 | Dynamic Mechani-cal Properties of Oil Palm Microfibril-reinforced Natural Rub-ber Composites显示文摘 | Joseph S Sreekumar P A Jose M K | 2010 | Journal of Applied Polymer Science2010,117,3: | 1 |
| 10 | Filamentous bulking sludge-a critical review显示文摘 | ANTONIO M KRISHNA P JOSEPH H | 2004 | Wat Res2004,38,4: | 1 |
| 11 | FeinbergLecture Stroke Therapy in the Year 2025 Burden, Breakthroughs, and Barriers to Progress显示文摘 | Joseph P Broderick MD William M | 2004 | Stroke2004,35,1: | 1 |
| 12 | An examination of the nature of trust in buyerseller relationships显示文摘 | POATRICIA M D JOSEPH P C | 1997 | Journal of Marketing1997,61,4: | 1 |
| 13 | Expression profile of eukaryotie translation factors in human cancer tissues and cell lines 显示文摘 | Joseph P O' Kemiek C M Othumpangat S | 2004 | Mol Carcinog2004,40,3: | 1 |
| 14 | Accurate spatial resolution estimates for reactive supersonic flow with detailed chemistry 显示文摘 | Joseph M Powers S P | 2005 | AIAA Journal2005,45,5: | 1 |
| 15 | An examination of the nature of trust in buyer- seller relationships显示文摘 | PATRICIA M DONEY JOSEPH P CANNON | 1997 | Journal of marketing1997,61,2: | 1 |
| 16 | A comparison of time delay estimators for the detection of leak noise signals in plastic water distribution pipes显示文摘 | Gao Y Brennan M J Joseph P F | 2006 | Journal of Sound and Vibration2006,292,35: | 1 |
| 17 | Understanding the Influence of National Culture on the Development of Trust显示文摘 | PATRICIA M DONEY JOSEPH P CANNON MICHAEL R MULLEN | 1998 | The Academy of Management Review1998,23,3: | 1 |
| 18 | Closed tubular automobile parts demand innovative welding methods显示文摘 | Michael G P Joseph M L | 1997 | Welding Journal1997,76,10: | 1 |
| 19 | Blockade of the renin-angiotensin- aldosterene system (RAAS) for primary prevention of non-valvular atri- al fibrillation :a systematic review and meta analysis of randomized controlled trials 显示文摘 | Khatib R Joseph P Briel M | 2012 | Nt J Cardio12012,13,: | 1 |
| 20 | Molecular andcellular mechanisms of cadmium carcinogenesis显示文摘 | Waisberg M Joseph P Hale | 2003 | Toxicology2003,192,23: | 1 |