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| 1 | Co-delivery of doxorubicin and quercetin via mPEG-PLGA copolymer assembly for synergistic anti-tumor efficacy and reducing cardio-toxicity显示文摘橡黄素(Que ) 是自然多功能的 bioflavonoid,并且为减少不利副作用并且提高化学疗法的药的反肿瘤功效显示出大潜力。然而,它的临床的申请在生理的系统由于很低的溶解度和结构的不稳定性被限制。此处,我们共同交付由开发 amphiphilic 聚合物包括的 biocompatible nanocarrier 的恐水病的橡黄素和吸水的 doxorubicin (纪录影片) , methoxy poly (乙烯乙二醇) 并且 poly (D, L-lactide-co-glycolide ) 分别地。反肿瘤和这个系统的预防功效被评估在细胞并且动物模型。我们说明的调查结果 Dox-Que nanoparticulate 明确的表达保护了正常脉管的 endothelial 房间免受免费的任何一个或 nanoparticulate 的伤害导致 doxorubicin 的 cytotoxicity 和增加的癌症房间死亡。与免费 doxorubicin 和它的 nanoformulation 相比,用我们的 nanosystem 的橡黄素和 doxorubicin 的合作交货 synergistically 禁止了肿瘤生长,当在浆液维持心脏的功能指示物的正常层次并且在心织物恢复组织病理学说的损坏时。这研究为提高反癌症药功效并且减少 nanoparticulate 表明有希望的策略正常纸巾上的导致化疗的毒性。 | Waseem Akhtar Qureshi Ruifang Zhao Hai Wang Tianjiao Ji Yanping Ding Ayesha Ihsan Ayeesha Mujeeb Guangjun Nie Yuliang Zhao | 2016 | Science Bulletin2016，61，21： | 9 |
| 2 | Microstructure Study in Slow Neutron Irradiated Bi-2223显示文摘The effect of slow neutron irradiation at a low Auence of about 10^(8)n/cm^(2) on the microstructures of Bi-2223 polycrystalline samples was observed by transmission electron microscopy.By comparative study of the defect structures in a given area in one sample,we get evidence for the flux pinning enhancement by low Auence slow neutron irradiation. | SHEN Guangjun JI Helin JIN Jirong JIN Xin ZHANG Yitong XU Xiaonong YAO Xixian | 1993 | Chinese Physics Letters1993，10，1： | 0 |
| 3 | Formation and Growth of Stacking Fault in YBCO by Electron Irradiation显示文摘This paper studies a new electron irradiation effect of the formation,movement and growth of stacking fault in YBa_(2) Cu_(3) O_(6+x).The energy of electron irradiation is about 160keV.It would be a promising way to enhance the density of pinning centers. | SHEN Guangjun HAN Yongsheng JIN Jirong JIN Xin JI Helin YAO Xixian FAN Zhanguo | 1993 | Chinese Physics Letters1993，10，5： | 0 |
| 4 | Comparative Analysis on Two Kinds of Measurement Methods of Particulate Matters in Waste Gas of Low Velocity显示文摘In the current waste gas sampling of fixed source,it is required that deviation of tracking rate of constant velocity sampling should not be more than 10%.When flow rate of the waste gas is less than 5 m/s,the tracking rate can not meet this requirement.The sampling of fixed velocity can meet the requirement of particulate matter sampling on gas collection volume at low velocity.Through the comparison of two different methods for the determination of particulate matter in waste gas under the low flow velocity of flue gas,it was found that there were some differences between the fixed velocity measurement and the constant velocity measurement.The results showed that measurement result of the fixed velocity was higher than that of constant velocity measurement under low velocity.At the same time,the deviation of fixed velocity measurement was not obvious under different low velocity. | Li Weijun Ji Guangjun Yang Xianglin Zhang Xingyao Jing Yifeng | 2019 | Meteorological and Environmental Research2019，10，5： | 0 |
| 5 | Self-assembly of CXCR4 antagonist peptide-docetaxel conjugates for breast tumor multi-organ metastasis inhibition显示文摘As a representative chemotherapeutic drug,docetaxel(DTX)has been used for breast cancer treatment for decades.However,the poor solubility of DTX limits its efficacy,and the DTX based therapy increases the metastasis risk due to the upregulation of C-X-C chemokine receptor type 4(CXCR4)expression during the treatment.Herein,we conjugated CXCR4 antagonist peptide(CTCE)with DTX(termed CTCE-DTX)as an anti-metastasis agent to treat breast cancer.CTCE-DTX could selfassemble to nanoparticles,targeting CXCR4-upregulated metastatic tumor cells and enhancing the DTX efficacy.Thus,the CTCE-DTX NPs achieved promising efficacy on inhibiting both bonespecific metastasis and lung metastasis of triple-negative breast cancer.Our work provided a rational strategy on designing peptide-drug conjugates with synergistic anti-tumor efficacy. | Chen Li Jiayan Lang Yazhou Wang Zhaoxia Cheng Mali Zu Fenfen Li Jingyi Sun Yating Deng Tianjiao Ji Guangjun Nie Ying Zhao | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 0 |
| 6 | Submesoscale eddies in the East China Sea detected from SAR images显示文摘Seven-year(2005-2011)Synthetic Aperture Radar(SAR)images are applied to study oceanic eddies in the East China Sea.It is found that most of these eddies detected from the SAR images are less than 10 km,which are submesoscale eddies.Seasonal differences are evident in the distribution of eddies,with the highest and the lowest number of eddies noted in summer and winter,respectively.Since slick streaks in SAR images look dark,an eddy identified due to the slicks is referred to as“black eddy”.As a result of wave-current interactions in the zones of current shear,it can be seen that an eddy exhibits a bright curve,the eddy is called“white eddy”.During the seven years,95 black eddies and 50 white eddies are identified in the study area.Black eddies are found in the whole study area while white eddies are mainly distributed in the vicinity of the Kuroshio Current.This study suggests that the distribution of the white eddy is denser around the Kuroshio because of the strong shear in the Kuroshio region.In terms of the eddy sizes,white eddies are generally smaller than black eddies. | Yuxiang Ji Guangjun Xu Changming Dong Jingsong Yang Changshui Xia | 2021 | Acta Oceanologica Sinica2021，40，3： | 0 |
| 7 | Inhibitory Effects of 12 Chemical Agents against Alternaria alternata显示文摘[Objective]The paper was to screen highly efficient fungicides for the prevention and control of tobacco brown spot(Alternaria alternata).[Method]The inhibitory effects of 12 chemical agents against A.alternata were determined indoors by mycelium growth rate method.[Result]Toxicity test showed that 30%kresoxim-methyl·boscalid SC had the best inhibitory effect,with an EC_(50)of 1.05μg/mL,followed by 9%pyraclostrobin CS,with an EC_(50)of 2.09μg/mL.As a broad spectrum protective fungicide,77%copper calcium sulfate WP showed a low sensitivity against A.alternata in the petri dish test since it had a mechanism of action different from that of other chemical agents.[Conclusion]The study lays the foundation for subsequent screening of fungicides for the prevention and control of A.alternata in the field. | Shen Hong Zhang Jiatao Cui Zhiyan Sun Guangjun Li Bin Zhang Yongfeng Xu Chuantao Ai Yongfeng Song Guanglong Ji Xiuting Wang Xiaoqiang | 2020 | Plant Diseases and Pests2020，11，4： | 0 |
| 8 | Context-Aware Task Allocation for Quick Collaborative Responses显示文摘 | SUN Yuqing Matthias Farwick Patrick C.K. Hung Dickson K.W. Chiu JI Guangjun | 2012 | Chinese Journal of Electronics2012，21，3： | 0 |
| 9 | Nanotechnological strategies for prostate cancer imaging and diagnosis显示文摘The high incidence rates and complicated subtypes of prostate cancer(PCa)call for the demand of the precise diagnostic and therapeutic strategies.Current clinical imaging techniques,such as MRI,CT,and ultrasonography are difficult to accurately detect the early-stage tumor lesions,and biochemical assays or biopsies are invasive and cannot provide sufficient information for the PCa staging and classification.Nanotechnology has the potential to improve the accuracy of current diagnosis strategies by targeting specific PCa biomarkers and/or integrating multiple imaging modes.In this review,we briefly introduce current clinical PCa imaging strategies and their major limitations,and highlight representative works on nanoparticle-mediated multimode imaging strategies.We also discuss the challenges of nanotechnology-based PCa diagnosis,and come up with suggestions and perspectives. | Thecla Trinity Wheeler Pei Cao Muhammad Daniyal Ghouri Tianjiao Ji Guangjun Nie Yuliang Zhao | 2022 | Science China Chemistry2022，65，8： | 0 |
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