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| 1 | Neurologic aspects of cobalamin deficiency 显示文摘 | Healton EB Savage DG Brust JCM | 1991 | Medicine1991，70，： | 1 |
| 2 | Fetal erythropoietin levels in pregnancies complicated by meconium passage:does meconium suggest fetal hypoxia显示文摘 | Jazayeri A Politz L Tsibris JCM | 2000 | Am J Obstet Gynecol2000，183，2： | 1 |
| 3 | Growth hormone,insulin like growt h factor and the kidney显示文摘 | Krieg RJ Santos F Chan JCM | 1995 | Kidney Int1995，48，： | 1 |
| 4 | Neurologic aspects of cobalamin deficiency显示文摘 | Heahon EB SavageDG Brust JCM etal | 1991 | Medicine1991，70，： | 1 |
| 5 | Digital simulation of randomprocesses and its applications 显示文摘 | SHINOZUKA M JCM | 1972 | Journal of Sound andVibration1972，29，1： | 1 |
| 6 | Catalytic mechanism and product specificity of cyclodextrin glycosyltransferase, a prototypical transglycosylase from the a-amylase family显示文摘 | Uitdehaag JCM van der Veen BA Dijkhuizen L | 2002 | Enzyme and Microbial Technology2002，30，3： | 1 |
| 7 | Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome as acomplication of preeclampsia in pregnant women increases the amount of cell-free fetal and maternal DNA in maternal plasma and serum 显示文摘 | Swinkels DW de KoK JB Hendriks JCM | 2002 | Clin Chem2002，48，4： | 1 |
| 8 | Acute ventricular hemorrhage in adults with hydrocephalus managed by corpus callosotomy and fenestration of the septum pellucidum显示文摘 | Holtzman RNN Brust JCM Bowers PP | 2001 | Neurosurgery2001，95，： | 1 |
| 9 | The NRG1 gene is frequentlysilenced by methylation in breast cancers and is a strong candidatefor the 8p tumour suppressor gene显示文摘 | Chua YL Ito Y Pole JCM | 2009 | Oncogene2009，28，46： | 1 |
| 10 | Postoperative pain following the use of two ddifferent intracanal medications显示文摘 | GamaTGV de Oliveira JCM Abad EC | 2008 | Clin Oral Investig2008，12，4： | 1 |
| 11 | Percutaneous cholecystostomy for the treatment of acute cholecystitis in the critically ill and elderly显示文摘 | Li JCM Lee DWH Lai CW | 2004 | Hong Kong Med J2004，10，： | 1 |
| 12 | Vitamin E ameliorates kidney injury in an experimental model of immunoglobulin A nephropathy显示文摘 | Trachtman H Chan JCM Chan W | 2006 | Pediatr Res2006，40，： | 1 |
| 13 | Computetional biomechanical modelling of the lumbar spine using marching-cubes surface smoothened finite element voxel meshing 显示文摘 | Wang ZL Teo JCM Chui CK | 2005 | Computer Methods and Programs in Biomedicine2005，80，： | 1 |
| 14 | Elastin as a biomaterial for tissue engineering显示文摘 | Daamen WF Veerkamp JH van Hest JCM | | 0，，： | 1 |
| 15 | Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients 显示文摘 | Kwa SLS Lebesque JV Theuws JCM | 1998 | Int J Radiat Oncol Biol Phys1998，42，： | 1 |
| 16 | Heterogeneous meshing and biomechanical modeling of the human spine 显示文摘 | Teo JCM Chui CK Wang ZL etal | 2007 | Medical Engineering and Physics2007，29，： | 1 |
| 17 | Radiation pneumonitis as a function of mean lung dose: a analysis of Pooled data of 540 Patients 显示文摘 | Kwa SLS Lebesque JV Thenws JCM | 1998 | Int J Radiat Oncol Biol Phys1998，42，1： | 1 |
| 18 | Carotiol intima-media thickness at different sites:relation to incident myocardial infarction显示文摘 | Witteman JCM Hofman A Bots ML | 2002 | Eur Heart J2002，23，： | 1 |
| 19 | Sodium and po tassium intake and risk of cardiovascular events and all-cause mor- tality: the Rotterdam study显示文摘 | Geleijnse JM Witteman JCM Stijnen T | 2007 | Eur J Epidemiol2007，，： | 1 |
| 20 | Gene expression arrays as a tool to unravel mechanisms of normal tissue radiation injury and prediction of response显示文摘Over the past 5 years there has been a rapid increase in the use of microarray technology in the field of cancer research. The majority of studies use microarray analysis of tumor biopsies for profiling of molecular characteristics in an attempt to produce robust classifi ers for prognosis. There are now several published gene sets that have been shown to predict for aggressive forms of breast cancer, where patients are most likely to benefit from adjuvant chemotherapy and tumors most likely to develop distant metastases, or be resistant to treatment. The number of publications relating to the use of microarrays for analysis of normal tissue damage, after cancer treatment or genotoxic exposure, is much more limited. A PubMed literature search was conducted using the following keywords and combination of terms: radiation, normal tissue, microarray, gene expression profi ling, prediction. With respect to normal tissue radiation injury, microarrays have been used in three ways: (1) to generate gene signatures to identify sensitive and resistant populations (prognosis); (2) to identify sets of biomarker genes for estimating radiation exposure, either accidental or as a result of terrorist attack (diagnosis); (3) to identify genes and pathways involved in tissue response to injury (mechanistic). In this article we will review all (relevant) papers that covered our literature search criteria on microarray technology as it has been applied to normal tissue radiation biology and discuss how successful this has been in defining predisposition markers for radiation sensitivity or how it has helped us to unravel molecular mechanisms leading to acute and late tissue toxicity. We also discuss some of the problems and limitations in application and interpretation of such data. | Jacqueline JCM Kruse Fiona A Stewart | 2007 | World Journal of Gastroenterology2007，13，19： | 1 |
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