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| 1 | TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation显示文摘Transforming growth factor-beta(TGF-β)/bone morphogenetic protein(BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcomes, i.e., skeletal, extra skeletal anomalies, autoimmune, cancer, and cardiovascular diseases. Phosphorylation of TGF-β(I/II) or BMP receptors activates intracellular downstream Smads, the transducer of TGF-β/BMP signals. This signaling is modulated by various factors and pathways, including transcription factor Runx2. The signaling network in skeletal development and bone formation is overwhelmingly complex and highly time and space specific.Additive, positive, negative, or synergistic effects are observed when TGF-β/BMP interacts with the pathways of MAPK, Wnt, Hedgehog(Hh), Notch, Akt/m TOR, and mi RNA to regulate the effects of BMP-induced signaling in bone dynamics. Accumulating evidence indicates that Runx2 is the key integrator, whereas Hh is a possible modulator, mi RNAs are regulators, and b-catenin is a mediator/regulator within the extensive intracellular network. This review focuses on the activation of BMP signaling and interaction with other regulatory components and pathways highlighting the molecular mechanisms regarding TGF-β/BMP function and regulation that could allow understanding the complexity of bone tissue dynamics. | Md Shaifur Rahman Naznin Akhtar Hossen Mohammad Jamil Rajat Suvra Banik Sikder M Asaduzzaman | 2015 | Bone Research2015，3，1： | 53 |
| 2 | Hydrotherapy Versus Conventional Land-Based Exercise for the Management of Patients With Osteoarthritis of the Knee: A Randomized Clinical Trial显示文摘 | Silva Luciana E Valim Valeria Pessanha Ana Paula C Oliveira Leda M Myamoto Samira Jones Anamaria Natour Jamil | 2008 | Physical Therapy2008，，1： | 2 |
| 3 | Development of an analog maximum power point tracker for photovoltaic panel 显示文摘 | Abu Tariq Jamil Asghar M S | 2005 | IEEE Power Electronics and Drives System2005，，1： | 1 |
| 4 | Microsomal triglyceride transfer protein显示文摘 | Wetterau J R Lin M C Jamil H | 1997 | Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism1997，1345，： | 1 |
| 5 | Increasing the efficiency of sorghum water extract by mixing with lower doses of isoproturon to control weeds in wheat 显示文摘 | Jamil M Cheema Z A Khaliq A | 2005 | International Journal of Agriculture & Biology2005，7，5： | 1 |
| 6 | An electrochemical and analytical approach to the inhibition mechanism of an amino-alcohol-based corrosion inhibitor for reinforced concrete显示文摘 | Jamil H E Montemor M F Boulif R | 2003 | Electrochimica Acta2003，，48： | 1 |
| 7 | Fabrication of a non-ce- ment binder using slag, palm oil fuel ash and rice husk ash with so- dium hydroxide 显示文摘 | Karim M R Zain M F M Jamil M | 2013 | Construction and Building Materials2013，49，： | 1 |
| 8 | Geochemistry of selected crude oils from Sabah and Sarawak显示文摘 | Jamil A S A Anwar M L Kiang E S P | 1991 | Bulletin of the Geological Society of Malaysia1991，28，： | 1 |
| 9 | Piezoelectric energy harvesting from a L-shaped beam-mass structure with an application to UAVs显示文摘 | Erturk A Jamil M R Daniel J I | 2009 | Journal of Intelligent Ma- terial Systems and Structures2009，20，： | 1 |
| 10 | Risk factor assessment of young patients with acute myocardial infarction显示文摘 | Jamil G Jamil M Alkhazraji H | 2013 | Am J Cardiovasc Dis2013，3，3： | 1 |
| 11 | The stochastic queue center problem 显示文摘 | Jamil M Baveja A Batta R | 1999 | Computers & Operations Research1999，26，14： | 1 |
| 12 | 显示文摘 | REGINA M M G ELISABETH W JAMILE R R | 2007 | Bioresource Technology2007，99，： | 1 |
| 13 | Nanoparticle-doped polymer-dispersed liquid crystal display显示文摘 | Jamil M Ahmad F Rhee J T | 2011 | Current Science2011，101，12： | 1 |
| 14 | Treatment of highly polluted paper mill wastewater by solar photocatalytic oxidation with synthesized nano TiO2 显示文摘 | Ghaly M Y Jamil T S E1-Seesy I E | 2011 | Chemical Engineering Journal2011，168，1： | 1 |
| 15 | Automatic Ontology Matching Using Application Semantics显示文摘 | Gal A Modica G Jamil H M | | AI Magazine0，2005，： | 1 |
| 16 | Envi- ronmental management accounting practices in small medium manufacturing finns显示文摘 | Jamil C Z M Mohamed R Muhammad F | 2015 | Procedia-Social and Be- havioral Sciences2015，172，27： | 1 |
| 17 | Cardiac and vascular pathophysiology in hypertension显示文摘 | Jamil M Alun H | 2003 | Heart2003，89，9： | 1 |
| 18 | Antibacterial activity of the essential oil from aristolochia India显示文摘 | Shaft P M Rosamma M K Jamil K | 2002 | Fitoterapia2002，73，5： | 1 |
| 19 | A literature Survey of Bench- mark Functions for Global Optimization Problems 显示文摘 | Jamil M Yang X S | 2013 | International Journal of Mathematical Modelling and Numerical Optimisation2013，4，2： | 1 |
| 20 | Successful and Unsuccessful Sales Calls, Measuring Salesperson Attributions and Behavioral Intentions显示文摘 | Dixon A L Spiro R L Jamil M | 2001 | Journal of Marketing2001，65，3： | 1 |
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