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6篇 您的检索式:作者名="J.Deng"
    题名 作者 年代 出处 被引量
1Number matters:control of mammalian mitochondrial DNA copy number显示文摘Regulation of mitochondrial biogenesis is essential for proper cellular functioning.Mitochondrial DNA(mtDNA) depletion and the resulting mitochondrial malfunction have been implicated in cancer,neurodegeneration,diabetes,aging,and many other human diseases.Although it is known that the dynamics of the mammalian mitochondrial genome are not linked with that of the nuclear genome,very little is known about the mechanism of mtDNA propagation.Nevertheless,our understanding of the mode of mtDNA replication has ad-vanced in recent years,though not without some controversies.This review summarizes our current knowledge of mtDNA copy number control in mammalian cells,while focusing on both mtDNA replication and turnover.Although mtDNA copy number is seemingly in excess,we reason that mtDNA copy number control is an important aspect of mitochondrial genetics and biogenesis and is essential for normal cellular function.Laura L.Clay Montier Janice J.Deng 2009Journal of Genetics and Genomics2009,36,3:24
2Dietary amylose and amylopectin ratio and resistant starch content affects plasma glucose, lactic acid, hormone levels and protein synthesis in splanchnic tissues显示文摘J.Deng X.Wu S.Bin T.‐J.Li R.Huang Z.Liu Y.Liu Z.Ruan Z.Deng Y.Hou Y.‐L.Yin 2010Journal of Animal Physiology and Animal Nutrition2010,,2:1
3Adverse life event and risk of cognitive impairment: a 5‐year prospective longitudinal study in Chongqing, China显示文摘J.Deng Y.Lian C.Shen Y.Chen M.Zhang Y.‐J.Wang H.‐D.Zhou 2012European Journal of Neurology2012,,4:1
4Dynamic buckling mechanism of pillar rockbursts induced by stress waves显示文摘Rockbursts are sudden and violent rock failures that can lead to huge production and equipment losses,injury or death of mining workers.Buckling has been regarded as one of the key mechanisms of rockbursts,which are often induced by dynamic loads from mining excavations,such as drilling and blasting in underground mining.The paper attempts to investigate the dynamic buckling mechanism of pillar rockbursts in underground mining,by considering rockbursts as a dynamic stability problem of underground rock structures.The results include:(1)A new explanation of the“sudden and violent”phenomenon of rockbursts,characterized by exponential growth of the amplitudes of transverse displacement responses,even in the presence of rock damping;(2)Identification of the critical role in inducing rockbursts of dynamic loads that bear frequencies approximately double the natural pillar frequency;(3)The greater influence on rockburst occurrence of the amplitude of dynamic component relative to the static component of loads;and(4)Quantification of the relative effects of stress waveform of dynamic loads on pillar rockbursts,which are in decreasing order if other parameters remain constant:rectangular,sinusoidal,and exponential waveforms.Application examples are provided and limitations of the approach are discussed.This research is motivated by the on-going and ubiquitous occurrence of rockbursts in underground excavations all around the world.In contrast to conventional methods that use rock specimens or rock materials to study rockbursts,this investigation emphasizes the structural effects on rockbursts,which has potential applications in hard rock mining engineering.J.Deng N.S.Kanwar M.D.Pandey W.-C.Xie 2019Journal of Rock Mechanics and Geotechnical Engineering2019,11,5:1
5CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery显示文摘Y.Han J.Deng L.Guo C 0,,:1
6Cellular repressor of E1A-stimulated genes inhibits human vascular smooth muscle cell apoptosis via blocking P38/JNK MAP kinase activation显示文摘Y.Han G.Wu J.Deng 0,,:1
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