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| 1 | 美国临床生化科学院检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物的应用显示文摘经美国临床生化科学院(NCAB)授权,由鄢盛恺教授组织学者、专家翻译审定2009年NCAB检验医学实践指南:睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的应用单行本(Catharine M.Sturgeon教授和Eleftherios P.Diaman-dis教授编辑)。该指南包含第1至6章共6部分内容,参加指南制订的专家阵容强大,分别从临床及检验角度对睾丸、前列腺、结直肠、乳腺及卵巢癌中肿瘤标志物的检测与临床应用方面的问题进行了详细阐述与说明,是目前国内外在肿瘤实验诊断方面的纲领性应用文件。不仅适合广大检验人员、临床医护人员学习使用,也非常适合相关仪器试剂生产厂商研发应用。本指南由刘洋、薛丽、林文涛、李江、梁红艳、顾兵、潘世扬、郑磊等翻译,姜晓峰、沈文梅、田亚平、鄢盛恺审校,最后由鄢盛恺统稿审定。本指南的翻译出版,不仅有助于我国检验人员和医护人员合理的检测和应用睾丸、前列腺、结直肠、乳腺及卵巢癌肿瘤标志物,对我国检验医学指南的编写与应用也有一定的借鉴作用。本刊特在本期刊发,以飨广大读者。 | 鄢盛恺 Ulf-Hkan Stenman Rolf Lamerz Leendert H.Looijenga Nils Brünner Michael J.Duffy Caj Haglund Mads Holten-Andersen Hans JФrgen Nielsen Francisco J.Esteva Nadia Harbeck Daniel F.Hayes Rafael Molina Daniel W.Chan Robert C.Bast Jr Ie-Ming Shih Lori J.Sokoll Gyrgy Slétormos 刘洋 梁红艳 姜晓峰 田亚平 薛丽 林文涛 顾兵 潘世扬 沈文梅 郑磊 李江 | 2012 | 临床检验杂志2012，30，2： | 32 |
| 2 | Choledocholithiasis: Evolving standards for diagnosis and management显示文摘胆石病,导致外科的干预的最普通的医药条件之一,在美国影响成年人口的约 10 % 。胆总管石病与胆囊石头在大约病人的 10%-20% 发展,文学建议至少经历胆囊炎的病人的 3%-10% 将有胆总管(CBD ) 石头。CBD 石头可以外科手术前地, intraoperatively 或手术后地被发现多重形式为包括实验室测试,超声,计算断层摄影术扫描(CT ) ,和磁性的回声 cholangiopancreatography (MRCP ) 为胆总管石病估计病人是可得到的。Intraoperative 胆管造影术能习惯性地或有选择地在胆囊炎期间被使用诊断 CBD 石头。为 CBD 石头的最普通的干预是 ERCP。另外的通常使用的干预包括 intraoperative 胆汁管探索,任何一个 laparoscopic 或 open。经皮, transhepatic 石头移动胆汁的清理的另外的新奇技术被设计了。与这些技术灵巧的设备和有技能的专业人员的可获得性在机构之中变化。预定干预被临床的状况经常支配。 | Marilee L Freitas Robert L Bell Andrew J Duffy | 2006 | World Journal of Gastroenterology2006，12，20： | 30 |
| 3 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 4 | Evolution of surgical skills training显示文摘外科的训练正在变化:100 年传统被法律、道德的担心为耐心的安全,工作小时限制,手术室时间的费用,和复杂并发症正在质问。训练的外科的模拟和技巧提供一个机会在在生活病人上尝试他们前在手术室环境外面教并且练习先进技巧。当使用真实仪器和录像设备操作在一个盒子训练员模仿了“织物”,模拟训练能向前是同样直的。更先进的、虚拟现实模拟器现在为普遍使用可得到、准备好了。早系统表明了他们的有效性和歧视的能力。更新的系统启用全面课程和完整的程序的模拟的开发。医药教育是的毕业生的认证委员会(ACGME ) 要求了训练和评估的新奇方法的发展。外科的组织正在打电话让方法保证技巧的维护,并且,进展 surgical 训练信任外科医生作为技术上能干。在他们的当前的形式的模拟器被表明了改进外科的居民的手术室表演。训练课程标准化的开发仍然是一个迫切、重要的议程,特别地为最小的侵略外科。一条创新、进步的途径,从航空的域借经验,能为外科的训练的下一个世纪提供基础,保证产品的质量。当技术发展,我们练习的方法将继续演变,到医生和病人的利益。 | Kurt E Roberts Robert L Bell Andrew J Duffy | 2006 | World Journal of Gastroenterology2006，12，20： | 8 |
| 5 | Dementia and osteoporosis in a geriatric population: Is there a common link?显示文摘AIM To determine the existence of a common pathological link between dementia and osteoporosis through reviewing the current evidence base. METHODS This paper reviews the current literature on osteoporosis and dementia in order to ascertain evidence of a common predisposing aetiology. A literature search of Ovid MEDLINE(1950 to June 2016) was conducted. The keywords 'osteoporosis', 'osteoporotic fracture', 'dementia' and 'Alzheimer's disease'(AD) were used to determine the theoretical links with the most significant evidence base behind them. The key links were found to be vitamins D and K, calcium, thyroid disease, statins, alcohol and sex steroids. These subjects were then searched in combination with the previous terms and the resulting papers manually examined. Theoretical, in vitro and in vivo research were all used to inform this review which focuses on the most well developed theoretical common causes for dementia(predominantly Alzheimer's type) and osteoporosis.RESULTS Dementia and osteoporosis are multifaceted disease processes with similar epidemiology and a marked increase in prevalence in elderly populations. The existence of a common link between the two has been suggested despite a lack of clear pathological overlap in our current understanding. Research to date has tended to be fragmented and relatively weak in nature with multiple confounding factors reflecting the difficulties of in vivo experimentation in the population of interest. Despite exploration of various possible mechanisms in search for a link between the two pathologies, this paper found that it is possible that these associations are coincidental due to the nature of the evidence available. One finding in this review is that prior investigation into common aetiologies has found raised amyloid beta peptide levels in osteoporotic bone tissue, with a hypothesis that amyloid beta disorders are systemic disorders resulting in differing tissue manifestations. However, our findings were that the most compelling evidence of a common yet independent aetiology lies in the APOE4 allele, which is a well-established risk for AD but also carries an independent association with fracture risk. The mechanism behind this is thought to be the reduced plasma vitamin K levels in individuals exhibiting the APOE4 allele which may be amplified by the nutritional deficiencies associated with dementia, which are known to include vitamins K and D. The vitamin theory postulates that malnutrition and reduced exposure to sunlight in patients with AD leads to vitamin deficiencies. CONCLUSION Robust evidence remains to be produced regarding potential links and regarding the exact aetiology of these diseases and remains relevant given the burden of dementia and osteoporosis in our ageing population. Future research into amyloid beta, APOE4 and vitamins K and D as the most promising aetiological links should be welcomed. | Candice L Downey Adam Young Emily F Burton Simon M Graham Robert J Macfarlane Eva-Maria Tsapakis Eleftherios Tsiridis | 2017 | World Journal of Orthopedics2017，8，5： | 6 |
| 6 | Controversies in the treatment of gastroesophageal reflux and achalasia显示文摘胃的食道的倒流疾病(GERD ) 和弛缓不能的有效治疗为这二作为标准答案建立了最小的侵略外科的 laparoscopic 外科的巨大的成功与更低的病态和死亡调节,更短的医院停留,更快的康复,和不太手术后的疼痛。在 GERD 的处理的一争吵作为比较喜欢的处理在 laparoscopic 反倒流外科(LARS ) 附近演变让 Barrett 的食管和过程的潜力减少食管的腺癌的风险。GERD 也与呼吸症状,气喘和喉的损害被联系了,并且第二争吵推动全部或部分的 fundoplication 是否是为 GERD 的更适当的处理的讨论。在 GERD 的处理的一种新、有希望的选择是 endoluminal 治疗。这种新处理选择的三种类型将被讨论:送到更低的食道的括约肌的射频精力,在胃的食道的连接的一个机械障碍的创造,并且更低的食道的括约肌的直接内视镜的紧缩。Laparoscopic 外科为弛缓不能为 GERD 而且同样永久的痊愈作为很有效的治疗被讨论不仅。这评论为弛缓不能分析三种很重要的处理选择:药,灵魂膨胀,和外科的治疗。因为他们的短半衰期和可变吸收,在弛缓不能的处理的药同样唯一的真非侵略的选择由于穷人不象 LARS 一样有效食道的倒空。第二种处理选择,灵魂膨胀,包含拉长更低的食管并且是仍然为弛缓不能考虑了最有效的非外科的处理。最后,为弛缓不能的外科的治疗和有关这个 laparoscopic 处理的二主要争吵被讨论。第一包含肌切开术被扩大到到胃上的程度,并且第二使反倒流过程的必要性和类型担心在肌切开术以后阻止 GERD。LARS 和 laparoscopic Heller 肌切开术是同意了在之上作为为 GERD 和弛缓不能的外科疗法的标准答案分别地。在一位富有经验的 laparoscopic 外科医生的手里,两个是为有有至少 90% 耐心的满足的优秀主观、客观的长期的结果的病人的安全、有效的治疗。 | Kurt E Roberts Andrew J Duffy Robert L Bell | 2006 | World Journal of Gastroenterology2006，12，20： | 4 |
| 7 | Metastatic recurrence to a solitary lymph node four years after hepatic lobectomy for primary hepatocellular carcinoma显示文摘This report describes a patient that developed recurrent metastatic hepatocellular carcinoma(HCC) to a suprapancreatic lymph node four years after being treated for primary HCC via complete left hepatectomy. Metastatic HCC was proven by pathologic confirmation. The report addresses the role of surgical resection as a treatment modality for recurrent HCC to solitary lymph nodes. The role of biological chemotherapy as adjuvant treatment is also addressed. | Michael L Caparelli Nathan J Roberts Timothy S Braverman Robert M Stevens Edward R Broun Shyam Allamaneni | 2016 | World Journal of Hepatology2016，8，23： | 2 |
| 8 | Drug-Induced Liver Injury Network (DILIN) Prospective Study: Rationale, Design and Conduct显示文摘 | Fontana Robert J Watkins Paul B Bonkovsky Herbert L Chalasani Naga Davern Timothy Serrano Jose Rochon James | 2009 | Drug Safety2009，，1： | 2 |
| 9 | Experimental and theoretical investigation of time setting polymer gels in porous media显示文摘 | Hubbard S Robert L J Sorbie K S | 1988 | Soc Petrol Engrs Reservoir Eval Engng1988，，： | 2 |
| 10 | Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett’s oesophagus: a prospective study显示文摘 | Thomas L Vaughan Linda M Dong Patricia L Blount Kamran Ayub Robert D Odze Carissa A Sanchez Peter S Rabinovitch Brian J Reid | 2005 | Lancet Oncology2005，，12： | 2 |
| 11 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 12 | Liver bioengineering:Current status and future perspectives显示文摘The present review aims to illustrate the strategies that are being implemented to regenerate or bioengineer livers for clinical purposes.There are two general pathways to liver bioengineering and regeneration.The first consists of creating a supporting scaffold,either synthetically or by decellularization of human or animal organs,and seeding cells on the scaffold,where they will mature either in bioreactors or in vivo.This strategy seems to offer the quickest route to clinical translation,as demonstrated by the development of liver organoids from rodent livers which were repopulated with organ specific cells of animal and/or human origin.Liver bioengineering has potential for transplantation and for toxicity testing during preclinical drug development.The second possibility is to induce liver regeneration of dead or resected tissue by manipulating cell pathways.In fact,it is well known that the liver has peculiar regenerative potential which allows hepatocyte hyperplasia after amputation of liver volume.Infusion of autologous bone marrow cells,which aids in liver regeneration,into patients was shown to be safe and to improve their clinical condition,but the specific cells responsible for liver regeneration have not yet been determined and the underlying mechanisms remain largely unknown.A complete understanding of the cell pathways and dynamics and of the functioning of liver stem cell niche is necessary for the clinical translation of regenerative medicine strategies.As well,it will be crucial to elucidate the mechanisms through which cells interact with the extracellular matrix,and how this latter supports and drives cell fate. | Christopher Booth Tom Soker Pedro Baptista Christina L Ross Shay Soker Umar Farooq Robert J Stratta Giuseppe Orlando | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 13 | Factors associated with 5-year survival of combined hepatocellular and cholangiocarcinoma显示文摘BACKGROUND Combined hepatocellular and cholangiocarcinoma(HCC/CC)is a rare primary hepatic malignancy which carries a poor prognosis due to its aggressive nature.Few centers have enough cases to draw definitive conclusions and there is limited understanding of prognosis.Given the rarity of HCC/CC,an analysis of large national cancer database was needed to obtain larger number of HCC/CC cases.AIM To identify associated factors for 5-year survival of HCC/CC.METHODS We conducted a retrospective study of The Surveillance,Epidemiology,and End Results(SEER)database obtained from SEER*Stat 8.3.6 software.Previously defined histology code 8180 for the International Classification of Disease for Oncology,3rd edition was used to identify HCC/CC cases from 2004 to 2015.We collected demographics,American Joint Committee on Cancer(AJCC)stage,treatment,tumor size,and survival data.These data were converted to categorical variables.The Shapiro-Wilk normality test was used to assess normal distribution.Mann-Whitney U test was used to compare continuous variables without normal distribution,and t-test was used to compare continuous variables with a normal distribution.The Kaplan-Meier survival curve analyzed 5-year survival.Univariate and multivariate logistic regression model was used to analyze factors associated with 5-year survival.Multivariate Cox proportional hazard regression was done on 5-year survival.We defined P<0.05 was statistically significant.RESULTS We identified 497 patients with the following characteristics:Mean age 62.4 years(SD:11.3),149(30.0%)were female,racial distribution was:276(55.5%)white,53(10.7%)black,84(16.9%)Asian and Pacific Islander(API),77(15.5%)Hispanic,and 7(1.4%)others or unknown.Stage I/II disease occurred in 41.5%and tumor size<50 mm was seen in 35.6%of patients.Twenty-four(4.8%)received locoregional therapy(LRT),119(23.9%)underwent resection,and 50(10.1%)underwent liver transplantation.The overall median survival was 6 mo[Interquartile range(IQR):1-22].After multivariate logistic regression,tumor size<50 mm[Odds ratios(OR):2.415,P=0.05],resection(OR:12.849,P<0.01),and transplant(OR:27.129,P<0.01)showed significance for 5-year survival.Age>60,sex,race,AJCC stages,metastasis,and LRT were not significant.However,API vs white showed significant OR of 2.793(CI:1.120-6.967).Cox proportional hazard regression showed AJCC stages,tumor size<50 mm,LRT,resection,and transplant showed significant hazard ratio.CONCLUSION HCC/CC patients with tumor size<50 mm,resection,and transplant were associated with an increase in 5-year survival.API showed advantageous OR and hazard ratios over white,black. | Tomoki Sempokuya Eric A Wien Robert J Pattison Jihyun Ma Linda L Wong | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 14 | Coronary vasoconsriction after percutaneous transluminal coronary angioplasty is attenuated by antiadrenergic agents 显示文摘 | Gregorini L Fajadet J Robert G | 1994 | Circulation1994，90，2： | 1 |
| 15 | Damage Evaluation of Concrete Test Specimens Related to Failure Analysis 显示文摘 | Berthelot J M Robert J L | 1990 | Journal of Engineering Mechanics ASCE1990，116，3： | 1 |
| 16 | On parameter identifiability of MIMO radar 显示文摘 | Li J Stoica P Xu L Z Roberts W | 2007 | IEEE Signal Processing Letters2007，14，12： | 1 |
| 17 | On the theory of flashover development显示文摘 | Graham T L Makhviladze G Roberts J P | 1995 | Fire Safety Journal1995，25，： | 1 |
| 18 | Application of Burkholderia cepacia and Trichoderma virens,alone and in combinations,a-gainst Meloidogyne incognita on bell pepper显示文摘 | MEYER S L F ROBERTS D P CHITWOOD D J | 2001 | Nematropica2001，，： | 1 |
| 19 | Quantiy aboveground biomass and estimating net aboveground primary production for wetland macrophytes using a non- destructive phenometric technique显示文摘 | Robert J D Daniel L C | 1998 | Aquactic Botany1998，62，： | 1 |
| 20 | Automatic Representation of Fingerprints for Data Compression by B-Spline Functions显示文摘 | Michael Chong M S Robert Gay K L Tan H N Liu J | 1992 | Pattern Recognition1992，25，10： | 1 |
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