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| 1 | Galvanic and asymmetry effects on the local electrochemical behavior of the 2098-T351 alloy welded by friction stir welding显示文摘Scanning electrochemical microscopy(SECM)and scanning vibrating electrode technique(SVET)were used to investigate the electrochemical behaviour of the top surface of the 2098-T351 alloy welded by friction stir welding(FSW).The SVET technique was efficient in identifying the cathodic and anodic weld regions.The welding joint(WJ),which comprises the thermomechanically affected zone(TMAZ)and the stir zone(SZ),was cathodic relative to the heated affected zone(HAZ)and the base metal(BM).The reactivities of the welding joint at the advancing side(AS)and the retreating side(RS)were analyzed and compared using SECM technique in the competition mode by monitoring the dissolved oxygen as a redox mediator in 0.005 mol L^-1 NaCl solution.The RS was more electrochemically active than the AS,and these results were correlated with the microstructural features of the welded alloy. | Mariana X.Milagre Uyime Donatus Naga V.Mogili Rejane Maria PSilva Barbara Victoria Gde Viveiros Victor F.Pereira Renato A.Antunes Caruline S.CMachado Joao Victor S.Araujo Isolda Costa | 2020 | Journal of Materials Science & Technology2020，42，10： | 2 |
| 2 | Diversity, Endemism and Conservation of Ferns(Polypodiales) in the Mexican Mountain Component显示文摘We analyzed the distributional patterns of95 selected species of leptosporangiate ferns inhabiting the Mexican Mountain Component, using grid-cells of one geographical degree as unit areas,applying endemism indices and richness and beta diversity analyses.Distributional data were obtained from several herbaria and specialized literature.Five grid-cells appear to be important for fern species richness, as they contain 35 to 49 species.These gridcells are located in the Sierra Madre Oriental(SMO),Trans-Mexican Volcanic Belt(TMVB) and the Sierra Madre del Sur(SMS).Mean richness by latitudinal belts of one degree showed that the belts with highest values are related to the TMVB and SMS.A total of 13grid-cells were recognized as important from theperspective of endemism; most of them are located also in the SMO, TMVB and SMS.The richest gridcells coincided with one of the main centres of endemism for ferns obtained in this study, located in the convergence of the southern part of the SMO, the eastern portion of the TMVB and the northern part of the SMS, reflecting the high humidity existing on the mountain slopes facing the Gulf of Mexico.Some important grid-cells recognized from richness and endemism analyses coincide with Mexican Natural Protected Areas.The beta diversity analysis showed a low degree of similarity among grid-cells, implying a high species replacement, as the result of environmental heterogeneity occurring in the Mexican mountain systems.On the other hand, the spatial analysis suggested a pattern of phytogeographical regionalization comprising twomain areas: the Mexican Transition Zone and the Mexican Central Plateau.Ferns play an important role in the Mexican biodiversity and contributing to the beta diversity of Mexico. | SANGINéS-FRANCO Celia LUNA-VEGA Isolda CONTRERAS-MEDINA Raúl ESPINOSA David TEJERO-DíEZ José Daniel RIVAS Gerardo | 2015 | Journal of Mountain Science2015，12，4： | 1 |
| 3 | Co- rrosion characterization of titanium alloys by electrochemical techniques显示文摘 | Sergio Luiz de Assis Stephan Wolynec Isolda Costa | 2006 | Electrochim Acta2006，51，： | 1 |
| 4 | Mouse rrlels in oneogenesis and cancer therapy 显示文摘 | Mafia VC Isolda C | 2006 | Clinical & Translational Oncology2006，8，5： | 1 |
| 5 | Effect of alpha prime due to 475?°C aging on fracture behavior and corrosion resistance of DIN 1.4575 and MA 956 high performance ferritic stainless steels显示文摘 | Maysa Terada Marcio F. Hupalo Isolda Costa Angelo F. Padilha | 2008 | Journal of Materials Science2008，，2： | 1 |
| 6 | Effect of molybdate on phosphating of NdFeB Magnets for Corrosion Protection显示文摘 | Adonis Marcelo Saliba-Silva Mara Cristina Lopes de Oliveira Isolda Costa | 2005 | Materials Research2005，8，2： | 1 |
| 7 | Mouse models in oncogenesis and cancer therapy显示文摘 | María Virtudes Céspedes Isolda Casanova Matilde Parre?o Ramón Mangues PhD | 2006 | Clinical and Translational Oncology2006，，5： | 1 |
| 8 | Corrosion characterization of titanium alloys by electrochemical techniques显示文摘 | Sérgio Luiz de Assis Stephan Wolynec Isolda Costa | 2005 | Electrochimica Acta2005，，8： | 1 |
| 9 | Corrosion characterization of titanium alloys byelectrochemical techniques显示文摘 | Stephan Wolynec Isolda Costa | 2006 | Electrochimica Acta2006，，51： | 1 |
| 10 | Self-assembling protein nanocarrier for selective delivery of cytotoxic polypeptides to CXCR4^(+) head and neck squamous cell carcinoma tumors显示文摘Loco-regional recurrences and distant metastases represent the main cause of head and neck squamous cell carcinoma(HNSCC) mortality. The overexpression of chemokine receptor 4(CXCR4) in HNSCC primary tumors associates with higher risk of developing loco-regional recurrences and distant metastases, thus making CXCR4 an ideal entry pathway for targeted drug delivery. In this context, our group has generated the self-assembling protein nanocarrier T22-GFP-H6, displaying multiple T22 peptidic ligands that specifically target CXCR4. This study aimed to validate T22-GFP-H6 as a suitable nanocarrier to selectively deliver cytotoxic agents to CXCR4^(+)tumors in a HNSCC model. Here we demonstrate that T22-GFP-H6 selectively internalizes in CXCR4^(+)HNSCC cells, achieving a high accumulation in CXCR4^(+)tumors in vivo, while showing negligible nanocarrier distribution in non-tumor bearing organs. Moreover, this T22-empowered nanocarrier can incorporate bacterial toxin domains to generate therapeutic nanotoxins that induce cell death in CXCR4-overexpressing tumors in the absence of histological alterations in normal organs. Altogether, these results show the potential use of this T22-empowered nanocarrier platform to incorporate polypeptidic domains of choice to selectively eliminate CXCR4^(+)cells in HNSCC. Remarkably, to our knowledge, this is the first study testing targeted proteinonly nanoparticles in this cancer type, which may represent a novel treatment approach for HNSCC patients. | Elisa Rioja-Blanco Irene Arroyo-Solera Patriciaálamo Isolda Casanova Alberto Gallardo Ugutz Unzueta Naroa Serna Laura Sánchez-García Miquel Quer Antonio Villaverde Esther Vázquez Ramon Mangues Lorena Alba-Castellón Xavier León | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 1 |
| 11 | Corrosion characterization of titanium alloys by electrochemical techniques显示文摘 | Stephan W Isolda C | 2006 | Electrochim Acta2006，51，： | 1 |
| 12 | Mouse Models in oneo- genesis and cancer therapy 显示文摘 | Maria VC Isolda C Matilde P | 2006 | Clinical and Translational 0ncology2006，8，5： | 1 |
| 13 | Masting effect on alpha and beta avian diversity in fragmented forests of relict?endangered Mexican Beech(Fagus grandifolia subsp.mexicana)显示文摘Background:Tropical montane cloud forests are one of the most important hotspots on Earth and show presence of relict-endemic and endangered species,representing about 14%of the total tropical forest worldwide.Synchronous seed production or masting in tropical montane cloud tree species is a widespread reproductive strategy of decidu-ous and evergreen broad-leaved tree associations to decrease costs of reproduction and ensure offspring.Masting event maintains a high avian diversity,which can be modified by phenological process(seed production and non-seed production).Methods:The main aim of this study was to assess alpha and beta avian diversity and whether the composition of the trophic guild modifies among phenological processes and between two fragmented relict-endangered Mexican Beech(Fagus grandifolia subsp.mexicana)forests(Medio Monte and El Gosco)in the Mexican state of Hidalgo.In addi-tion,we evaluated beechnut production.Results:We recorded 36 bird species,11 of them included in some conservation risk status,and 5 endemic species.Alpha diversity values were dissimilar in avian richness(q=0)among phenological processes and between frag-mented beech forests.Avian communities among three phenological processes and between fragmented forests were structurally similar,dominated during immature seeds the Brown-backed Solitaire(granivores-insectivores-frugivores);during mature seeds the White-crowned Parrot(Pionus senilis,granivores-frugivores);and the Dwarf Jay(Cyanolyca nana,insectivores)was abundant during low seed quality.The complementarity index was high among phenological processes and low between forests.We found a high bird turnover value between immature seeds—mature seeds and during mature seeds—low seed quality.Furthermore,a similar pattern was recorded between the two study forests.Seed production showed a high number of undamaged beechnuts in Medio Monte,while in El Gosco beechnuts were attacked by insects.Conclusions:Our results reflect that masting phenological process and contrasting study forests'structure influence the shifts in alpha and beta diversity of seed and non-seed bird consumers.Our study reaffirms the importance of continuing studies throughout masting in all the Mexican Beech forests to address regional efforts in preserving the relict-ecological interactions. | Ernesto CRodríguez-Ramírez Levinn Camacho-Islas Ana Paola Martínez-Falcón Isolda Luna-Vega Pilar Carbó-Ramírez | 2021 | Avian Research2021，12，4： | 0 |
| 14 | Drought effects on the plasticity in vessel traits of two endemic Magnolia species in the tropical montane cloud forests of eastern Mexico显示文摘本文旨在探讨气候变化如何影响两种特有墨西哥木兰的导管性状可塑性和其每年的年轮宽度。尽管如此,很少有研究评估干旱对墨西哥东部热带山地云林导管性状的影响。通过生长年轮的数字图像,我们对所研究的墨西哥木兰树种的径向生长率、树龄和导管性状可塑性进行了评估,比较了两种墨西哥木兰树种在干旱年和非干旱年的导管密度、水力直径和传导面积百分比。本研究首次对墨西哥两个热带山地云林中的两个濒危木兰树种(Magnolia vovidesii和M.schiedeana)的多孔木质部导管性状对长期气候变化的可塑性进行了分析。结果发现,当比较干旱和非干旱年份时,温度和降水量与年轮宽度的差异密切相关。扩散型多孔木质导管解剖结构具有很高的可塑性,这与所研究的两种木兰树种的温度和/或水的有效性有关。我们的结论是,与非干旱年份相比,对干旱年份的解剖学适应导致了导管性状的大量减少;这些可塑的适应性在植物长期环境胁迫下的水分运输以及生存的安全性方面起着重要的作用。 | Ernesto Chanes Rodríguez-Ramírez José Antonio Vázquez-García Ignacio García-González Othón Alcántara-Ayala Isolda Luna-Vega | 2020 | Journal of Plant Ecology2020，13，3： | 0 |
| 15 | Historical relationships of the Mesoamerican highlands,with emphasis on tropical montane cloud forests:a temporal cladistic biogeographical analysis显示文摘The historical relationships of nine areas of endemism of the tropical montane cloud forests(TMCFs)were analysed based on a temporal cladistic biogeographical approach.Three cladistic biogeographical analyses were conducted based on 29cladograms of terrestrial taxa by partitioning them into three time-slices,namely,Miocene,Pliocene,and Pleistocene.The results showed different area relationships over time.For the Miocene and Pliocene time slices,the Isthmus of Tehuantepec acted as a geographic barrier that fragmented the TMCFs into two portions:west of the Isthmus and east of the Isthmus.In the case of the Pleistocene,the TMCFs were broken into two portions,one related to the Neotropical region and the other to the Nearctic region.Furthermore,the analyses allowed us to detect the influences of different geological and paleoclimatological events on the distribution of the TMCFs over time.Therefore,the TMCFs current distribution might have been driven by geological events during the Miocene-Pliocene,whereas climatic fluctuations have the highest impact during the Pleistocene. | CASTRO-TORREBLANCA Marisol ESPINOSA David BUENO-HERNANDEZ Alfredo LUNA-VEGA Isolda | 2023 | Journal of Mountain Science2023，20，1： | 0 |
| 16 | Biocidal Effect of Gamma Radiation on the Ecology of Filamentous Fungal Populations Associated with Stone Deterioration显示文摘 | Douglas Boniek Isolda de Castro Mendes Antonio Femando Batista dos Santos Maria Aparecida de Resende Stoianoff | 2017 | Journal of Environmental Science and Engineering(A)2017，6，5： | 0 |
| 17 | 帕拉诗选显示文摘敬告读者作者对自己作品可能引发的不快概不负责:即使他也不好受。读者只能永远表示满意。撒伯流是个宗教学者,同时也是个幽默大王,他颠覆了基督教的三位一体教义他为自己的异端邪说承担过责任吗?即便有,你看他是怎么负责的!是多么荒谬的方式!一堆自相矛盾的奇谈怪论! | 尼卡诺尔·帕拉 莫沫(Isolda Morillo) 孙新堂(校) | 2019 | 大家2019，0，3： | 0 |
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