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| 1 | 超声波检测横向缺陷漏检案例分析显示文摘在船舶建造过程中发现大量的横向缺陷(氢致裂纹)被漏检,主要原因是超声波检测人员未能按照认可的探伤程序执行,不正确地选用探头和采用错误的扫查方式。结果导致上千米焊缝或上百个分段的返修。通过对不同项目横向缺陷案例分析,总结了漏检的主要原因,指出了横向缺陷在超声波检测中的典型特征及横向缺陷产生的根本原因。 | 王丽梅 王兴春 Andersen Isak | 2018 | 无损探伤2018，42，1： | 5 |
| 2 | Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol显示文摘One-carbon compounds,such as methanol,are becoming potential alternatives to sugars as feedstocks for the biological production of chemicals,fuels,foods,and pharmaceuticals.Efficient biological production often requires extensive genetic manipulation of a microbial host strain,making well-characterised and geneticallytractable model organisms like the yeast Saccharomyces cerevisiae attractive targets for the engineering of methylotrophic metabolism.S.cerevisiae strains S288C and CEN.PK are the two best-characterised and most widely used hosts for yeast synthetic biology and metabolic engineering,yet they have unpredictable metabolic phenotypes related to their many genomic differences.We therefore sought to benchmark these two strains as potential hosts for engineered methylotrophic metabolism by comparing their growth and transcriptomic responses to methanol.CEN.PK had improved growth in the presence of methanol relative to the S288C derivative BY4741.The CEN.PK transcriptome also had a specific and relevant response to methanol that was either absent or less pronounced in the BY4741 strain.This response included up-regulation of genes associated with mitochondrial and peroxisomal metabolism,alcohol and formate dehydrogenation,glutathione metabolism,and the global transcriptional regulator of metabolism MIG3.Over-expression of MIG3 enabled improved growth in the presence of methanol,suggesting that MIG3 is a mediator of the superior CEN.PK strain growth.CEN.PK was therefore identified as a superior strain for the future development of synthetic methylotrophy in S.cerevisiae. | Monica I.Espinosa Thomas C.Williams Isak S.Pretorius Ian T.Paulsen | 2019 | Synthetic and Systems Biotechnology2019，4，4： | 2 |
| 3 | Knowledge representations for the interactive selling of financial services显示文摘 | Felfemig A Isak K Kreutler G | 2007 | Information Systems and eBusiness Management2007，5，2： | 1 |
| 4 | A biomaterials viewpoint for the 2020 SARS-CoV-2 vaccine development显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has caused a considerable loss of life,morbidity,and economic distress since its emergence in late 2019.In response to the novel virus,public and private institutions around the world have utilized novel technologies to develop a vaccine in the hopes of building herd immunity and ending the pandemic.This review provides an overview of mechanisms and available data on the nascent vaccine technologies undergoing clinical trials to combat SARS-CoV-2,namely,those using protein subunits,viral vectors,mRNA,and DNA.Furthermore,we discuss the potential uses of biomaterials in improving the immunogenicity and safety of these vaccine technologies with the goal of improving upon newly-available technologies to combat future SARS-CoV-2 strains and other emerging viral pathogens. | Isak Jatoi Jingyu Fan | 2021 | Biomaterials Translational2021，2，1： | 1 |
| 5 | Assessment of symptom atic diabetic patients with normal nerve conduction studies: u tility of cutaneous silent periods and autonomic tests 显示文摘 | Koytak PK Isak B Borucu D | 2011 | Muscle Nerve2011，43，： | 1 |
| 6 | Anti-ischemic effects of multivalent dendrimeric A3 adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart显示文摘 | Chanyshev B Shainberg A Isak A | | 0，，03： | 1 |
| 7 | Evaluation of peripheral and autonomic neuropathy among patients with newly diagnosed impaired glucose tolerance显示文摘 | Isak B Oflazoglu B Tanridag T | 2008 | Diabetes Metab Res Rev2008，24，7： | 1 |
| 8 | Laser deposition of Metco 15E, Colmony 88 and VIM CRU 20 powders on cast iron and low carbon steel显示文摘 | Zoran Lestan Matjaz Milfelner Joze Balic Miran Brezocnik Isak Karabegovic | 2013 | The International Journal of Advanced Manufacturing Technology2013，，9： | 1 |
| 9 | Arsenic trioxide and thalidomide combination produces multi-lineage hematological responses in myelodysplastic syndromes patients, particularly in those with high pre-therapyEVII expression显示文摘 | RAZA A BUONAMICI S I ISAK L | 2004 | Leuk Res2004，28，8： | 1 |
| 10 | Brainstem auditory evoked potentials and middle latency auditory evoked po- tentials in patients with impaired glucose tolerance显示文摘 | Yitmen I Oflazoglu B Isak B | 2008 | Di- abet Med2008，25，7： | 1 |
| 11 | Suppression of inflammatory gene expression in T cells by Porphyromonas gingivalis is mediated by targeting MAPK signaling显示文摘在主人免疫者回答上正在增加 Porphyromonas gingivalis 的效果的了解。由半胱氨酸朊酶的 cytokines 和 chemokines 的降级以前被报导了。然而,精确机制由哪个 P。gingivalis 能改变细胞内部的发信号,并且这样增长和发炎,没被描述。我们以前从 P 由朊酶报导了使活跃之物 protein-1 (AP-1 ) 和 IL-2 的降级的抑制。gingivalis。在现在的学习,我们分析了 P 的效果。Jurkat T 房间信号 transduction 和随后的 IL-2 和 CXCL8 表示上的 gingivalis。我们发现了那 CXCL8,然而并非 IL-2,基因表示层次被可行 P 显著地压制。gingivalis。细胞内部的发信号的分析揭示了 P 的禁止的效果。c6 月和 c-Fos 上的 gingivalis,然而并非 NFκ B (p50 和 p65 ) , NFAT 或 STAT5 表示。这禁止的效果不由于激活 mitogen 的蛋白质 kinase (MAPK )(p38,英皇家空军之阶级最低之兵和 JNK ) 的抑制基因表示,但是相当由于蛋白质 kinase C (PKC ) 和 p38 phosphorylation 的预防由西方的污点分析示威了。而且, SOCS1 和 SOCS3 表示层次减少了与可行 P 跟随 Jurkat T 房间的处理。gingivalis。结果显示那 P。gingivalis 能由在 T 房间指向 MAPK 小径的活动压制煽动性的基因表示,它被使用 NF-κ 的特定的禁止者证实; B, PKC,英皇家空军之阶级最低之兵, p38 和 JNK。 | Hazem Khalaf Isak Demirel Torbjorn Bengtsson | 2013 | Cellular & Molecular Immunology2013，10，5： | 1 |
| 12 | A model of 'coupled' technology trander-A logistic curve approach 显示文摘 | Baruch Raz Isak Assa | 1988 | Technological Forecasting and Social Change1988，33，3： | 1 |
| 13 | A neurophysiological ap- proach to the complex organisation of the spine: F-wave dura- tion and the cutaneous silent period in restless legs syndrome 显示文摘 | Isak B Uluc K Salcini C | 2011 | Clin Neurophysiol2011，122，： | 1 |
| 14 | Vacuum arc plasma jets and their applications显示文摘 | Keidar Michael Beilis Isak I | 2003 | IEEE International Conference on Plasma Sci2003，，： | 1 |
| 15 | Madras motor neuron diseasein Turkey显示文摘 | Isak B Uluc K Tanridag T | 2009 | Amyotrophic Lateral Sclerosis2009，10，56： | 1 |
| 16 | Medial plantar and dorsal sural nerve conduction studies increase the sensitivity in the detection of neuropathy in diabetic patients显示文摘 | Uluc K Isak B Borucu D | 2008 | Clin Neurophysiol2008，119，4： | 1 |
| 17 | Medial plantar and dor- sal sural nerve conduction studies increase the sensitivityin the detection of neuropathy in diabetic patients 显示文摘 | Uluc K Isak B Borucu D | 2012 | Clin Neurophysiol2012，119，： | 1 |
| 18 | High yield manufacturing of fully screen-printed organic electrochemical transistors显示文摘The potential of the screen printing method for large-scale production of organic electrochemical transistors(OECTs),combining high production yield with low cost,is here demonstrated.Fully screen-printed OECTs of 1 mm^(2) area,based on poly(3,4-ethylenedioxythiophene)doped with poly(styrensulfonate)(PEDOT:PSS),have been manufactured on flexible polyethylene terephthalate(PET)substrates.The goal of this project effort has been to explore and develop the printing processing to enable high yield and stable transistor parameters,targeting miniaturized digital OECT circuits for large-scale integration(LSI).Of the 760 OECTs manufactured in one batch on a PET sheet,only two devices were found malfunctioning,thus achieving an overall manufacturing yield of 99.7%.A drain current ON/OFF ratio at least equal to 400 was applied as the strict exclusion principle for the yield,motivated by proper operation in LSI circuits.This consistent performance of low-footprint OECTs allows for the integration of PEDOT:PSS-based OECTs into complex logic circuits operating at high stability and accuracy. | Marzieh Zabihipour Roman Lassnig Jan Strandberg Magnus Berggren Simone Fabiano Isak Engquist Peter Andersson Ersman | 2020 | npj Flexible Electronics2020，4，1： | 1 |
| 19 | Extensions to the hybrid method of moments/uniform GTD formulation for sources located close to a smooth convex surface显示文摘 | Isak P Theron David B Davidson Ulrich Jakobus | 2000 | IEEE Trans Antennas Propagat2000，48，6： | 1 |
| 20 | X-ray diagnosis of impacted upper canines in panoramic radiographs and computed tomographs显示文摘 | Dr. Marita Freisfeld Isak Arne Dahl Andreas J?ger Dieter Drescher Heinrich Schüller | 1999 | Journal of Orofacial Orthopedics / Fortschritte der Kieferorthop?die1999，，3： | 1 |
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