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| 1 | Hepatocellular carcinoma treated with transarterial chemoembolization: Dynamic perfusion-CT in the assessment of residual tumor显示文摘AIM: To asses the value of computed tomography (CT)-perfusion in the detection of residual hepatocellular carcinoma (HCC) vascularization after transarterial chemoembolization (TACE). METHODS: Thirty-two consecutive patients were pro-spectively included in this study. All patients had liver cirrhosis and a conf irmed HCC lesion which was treated with TACE. One month after treatment, perfusion measurements of treated lesions were carried out. The CTperfusion (CT-p) protocol was performed with 16 slice multidetector computed tomography which included the following parameters: 8 dynamic slices/scan per 40 scans after iv injection of 50 mL of iodinated contrast (350 mg/mL) at a flow rate of 6 mL/s. Treated lesions were evaluated using dedicated perfusion software, which generated a quantitative colour map of perfusion. The following parameters were considered: hepatic perfusion (HP), arterial perfusion (AP), blood volume (BV), hepatic perfusion index (HPI), and time to peak (TTP). Perfusion parameters were described with quartile values of their distribution and statistically analyzed. RESULTS: Perfusion parameters of the treated lesions could be quantitatively assessed using CT-p analysis. The presence of residual tumor tissue was observed in 13 of the 32 patients. The values of the perfusion parameters measured within the relapse tissue were: HP (mL/100 g per minute): median = 44.4 (1stqt = 31.3, 3rdqt = 55.8); BV (mL/100 g): median = 18.7 (1stqt = 11.5, 3rdqt = 22.5); AP (mL/min): median = 39.0 (1stqt = 36.5, 3rdqt = 61.3); HPI (%): median = 34.0 (1stqt = 30.4, 3rdqt = 38.9); TTP (s): median = 17.3 (1stqt = 15.8, 3rdqt = 26.5). With the use of the univariate paired Wilcoxon signed rank test, HP, AP and HPI were shown to be significantly higher (P<0.001) in the relapse site than in the primary lesion. The BV and TTP parameters showed a tendency to be greater and lower, respectively, in the relapse site than in the primary lesion. CONCLUSION: In patients with HCC treated with TACE, CT-p provides measurement of flow parameters related to residual arterial structures in viable tumor, thus helping in the assessment of therapeutic response. | Davide Ippolito Pietro Andrea Bonaff ini Laura Ratti Laura Antolini Rocco Corso Ferruccio Fazio Sandro Sironi | 2010 | World Journal of Gastroenterology2010，16，47： | 15 |
| 2 | 加载方向变化对细晶花岗岩凯塞效应的影响显示文摘进行了单轴压缩试验条件下重复加载时加载方向变化对细晶花岗岩凯塞效应的影响试验研究。试验发现,加载方向不变或加载角度变为7°时,岩石的凯塞效应明显;加载角度为10°和15°时,部分试件由于受试验环境、试件加工等因素的影响观测不到凯塞效应。试验统计数据表明,重复加载时加载方向变化越大,其凯塞效应越弱。研究同时发现:加载方向变化对凯塞效应的影响还取决于岩石的受力状态,单轴压缩状态下,岩石受力状态单一,重复加载时加载方向的轻微变化不会影响岩石对历史应力的记忆能力;劈裂状态下,圆盘试样应力状态复杂,加载方向的轻微变化足以引起试样内应力的重分布,进而影响岩石的凯塞效应。 | 谢强 江小城 余贤斌 Carlos inis da Gama | 2010 | 煤炭学报2010，35，10： | 6 |
| 3 | Individual function difference of Runx2 isoforms in bone formation by RNA inferen显示文摘 | Li YL INi ZJ Zheng SP | 2008 | Cell Biol Int2008，32，3： | 1 |
| 4 | TranscranialDopp ler as sessment of cerebrovascular reactivity in symp tomatic and asymp to matic severe carotid stenosis显示文摘 | Silvestrini M Troisi E Cup ini LM | 1996 | Stroke1996，27，： | 1 |
| 5 | Do ar- senosugars pose a risk to human health? The comparative toxicities of a trivalent and pentavalent arsenosugar 显示文摘 | Andrewes P Demar ini D M Funasaka K | 2004 | Environ Sci Technol2004，，38： | 1 |
| 6 | Bone fraetures and hypoglycenfic treatment in type 2 diabetic patients:a case-control study显示文摘 | Monami M Crcsci B Colornl ini A | 2008 | Diabetes Care2008，31，2： | 1 |
| 7 | Thermal fracture mechanisms in ceramic thermal barrier coatings 显示文摘 | Kk ini K Choules B D Takeuchi Y R | 1997 | journal of Thermal Spray Teehno logy1997，6，1： | 1 |
| 8 | The Common Defense and Great-Power Responsibilities显示文摘 | Inis L.Claude Jr | | 0，，05： | 1 |
| 9 | A role for the ELAV RNA-bind-ing proteins in neural stem cells:stabilization of Msi1 mRNA显示文摘 | Ratti A Fal ini C Cova L | | 0，，7： | 1 |
| 10 | Effect of hospital volume, surgeon experience, and surgeon volume on pa- tient outcomes after pancreaticoduodenectomy 显示文摘 | Max Schmidt C Olivier Tun'ini Purvi Parikh | 2010 | Arch Surg2010，145，7： | 1 |
| 11 | Oxidative damages in the DNA, lipids, and proteins of rats exposed to isofluranes and alcohols显示文摘 | KIM H OH E INI H | 2006 | Toxicology2006，220，23： | 1 |
| 12 | Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians显示文摘 | Menzaghi C Coco A Salvem ini L | 2005 | J Clin Endocrinol Metab2005，91，7： | 1 |
| 13 | Learning without local minima in radial basis function networks显示文摘 | BIANCH INI M Frasconi P GORI M | 1995 | IEEE Transon Neural Networks1995，6，3： | 1 |
| 14 | Adrenal glandcysts :our experinee显示文摘 | Danza FM De Mar inis L Mancini A | 1993 | Minerva Chir1993，48，2122： | 1 |
| 15 | Large vessel cerebral atherosclerosis is not in direct association with neuropathologieal le- sions of Alzheimer' s disease 显示文摘 | LUoto INI HalKonen 3 tlaapasalo n | 2009 | Eur Neurol2009，62，2： | 1 |
| 16 | 查看详情显示文摘 | Maloj(c)i(c) G Piantanida I Marini(c) M (Z)ini(c) M Marjanovi(c) M Kralj M Paveli(c) K Schneider H | | 0，，： | 1 |
| 17 | Determination of the chemical diffusion coefficient of lithium in LiFePO4 显示文摘 | Pros ini P P Lisi M Zane D | 2002 | Solid State Ionics2002，148，12： | 1 |
| 18 | Cerebrovascular reactivity and subcortical infarctions显示文摘 | Cup ini LM DiomediM Placidi F | 2001 | Arch Neurol2001，58，57： | 1 |
| 19 | An',dysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport 显示文摘 | COLOMBO P BETI'INI R SANTI P | 1996 | J Control Release1996，39，： | 1 |
| 20 | Sphenoid wing meningiomas:Neurosurgical recommendations显示文摘 | Kanaan INI | 2004 | Int Cong Series2004，1259，： | 1 |
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