|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reduced bone mineral density and altered bone turnover markers in patients with non-cirrhotic chronic hepatitis B or C infection显示文摘AIM: Previous studies suggest that loss of bone mineral density (BMD) frequently occurs in patients with chronic viral liver disease, presenting with histologically proven liver cirrhosis. However, little is known about the occurrence of bone disease in non-cirrhotic patients with chronic hepatitis B or C. Therefore, it was the aim of this study to evaluate this particular population for BMD and bone turnover markers.METHODS: Biochemical markers of bone turnover and BMD were measured in 43 consecutive patients with HCV (n = 30)or HBV (n = 13) infection without histological evidence for liver cirrhosis. Mean age was 49 years (range 26-77 years). BMD was measured by dual X-ray absorptiometry in the femoral neck (FN) and the lumbar spine (LS) region. In addition, bone metabolism markers were measured.RESULTS: BMD was lowered in 25 (58%) of the patients with chronic hepatitis B or C (FN: 0.76 (0.53-0.99); LS:0.96 (0.62-1.23) g/cm2). Eight (32%) osteopenic patients were diagnosed with osteoporosis. Bone-specific alkaline phosphatase (P = 0.005) and intact parathyroid hormone (iPTH) (P = 0.001) were significantly elevated in the more advanced stages of fibrosis. Mean 7-score value was lower in patients with chronic hepatitis C as compared to patients suffering from chronic hepatitis B; however, the difference was not statistically significant (P = 0.09).CONCLUSION: There was a significantly reduced BMD in non-cirrhotic patients with chronic hepatitis B or C infection. Alterations of bone metabolism already occurred in advanced liver fibrosis without cirrhosis. According to our results, these secondary effects of chronic viral hepatitis should be further investigated. | Ingolf Schiefke Andreas Fach Marcus Wiedmann Andreas V.Aretin Eva Schenker Gudrun Borte Manfred Wiese Joachim Moessner | 2005 | World Journal of Gastroenterology2005，11，12： | 23 |
| 2 | The dynamics of color signals in male threespine sticklebacks Gasterosteus aculeatus显示文摘 | Meike HIERMES Ingolf P. RICK Marion MEHLIS Theo C. M. BAKKER | 2016 | Current Zoology2016，62，1： | 4 |
| 3 | “En bloc ” caudate lobe and inferior vena cava resection following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal and liver metastasis of colorectal cancer显示文摘There are diverse protocols to manage patients with recurrent disease after primary cytoreductive surgery(CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC) for peritoneal carcinomatosis. We describe a case of metachronous liver metastasis after CRS and HIPEC for colorectal cancer, successfully treated with a selective metastectomy and partial graft of the inferior vena cava. A 35-year-old female presented with a large tumour in the cecum and consequent colonic stenosis. After an emergency right colectomy, the patient received adjuvant chemotherapy. One year later she was diagnosed with peritoneal carcinomatosis, and it was decided to carry out a CRS/HIPEC. After 2 years of total remission, an isolated metachronous liver metastasis was detected by magnetic resonance imaging surveillance. The patient underwent a third procedure including a caudate lobe and partial inferior vena cava resection with a prosthetic graft interposition, achieving an R0 situation. The postoperative course was uneventful and the patient was discharged on postoperative day 17 after the liver resection. At 18-mo follow-up after the liver resection the patient remained free of recurrence. In selected patients, the option of re-operation due to recurrent disease should be discussed. Even liver resection of a metachronous metastasis and an extended vascular resection are acceptable after CRS/HIPEC and can be considered as a potential treatment option to remove all macroscopic lesions. | Patricia Sánchez-Velázquez Nicolas Moosmann Ingolf T?pel Pompiliu Piso | 2016 | World Journal of Gastroenterology2016，22，46： | 3 |
| 4 | 心室辅助装置在小儿原发性心肌病并发心力衰竭中的应用价值显示文摘目的:评价心室辅助装置在小儿原发性心肌病并发心力衰竭中的应用价值。方法:4例扩张型心肌病(DCM)患儿采用手术安装心室辅助装置代替并发心室行使泵功能。术后常规给予抗凝剂苯丙酸豆素和抗血小板药物阿司匹林以防止血栓事件的发生。术后每日采用毛细血管法测定INR,同时严密观察管道有无血栓形成。结果:1例6个月男婴安装左室辅助装置(LVAD);1例40个月男性患儿初安装LVAD,后因继发右心衰竭于9周后复手术安装双侧心室辅助装置(BIVD);1例13岁女性患儿和1例15岁男性患儿因全心力衰竭安装BIVD;4例目前心功能均恢复良好。其中6个月男婴已心脏移植,15岁男性患儿因心功能和心肌收缩力恢复良好,予撤机后痊愈出院。结论:对于原发性心肌病并发心力衰竭患儿,应用心室辅助装置如Berlin Heart系统进行治疗,效果良好。 | 杨晓东 陈秀玉 黄敏 Joerg Ingolf Stein | 2008 | 临床心血管病杂志2008，24，1： | 2 |
| 5 | Influence of lighting environment on social preferences in sticklebacks from two different photic habitats.I.mate preferences of wild-caught females显示文摘Ultraviolet(UV)A signals(320-400 nm)are important in mate choice in numerous species.The sensitivity for UV signals is not only assumed to be costly,but also expected to be a function of the prevailing ecological conditions.Generally,those signals are favored by selection that efficiently reach the receiver.A decisive factor for color signaling is the lighting environment,especially in aquatic habitats,as the visibility of signals,and thus costs and benefits,are instantaneously influenced by it.Although ecological aspects of color signal evolution are relatively well-studied,there is little data on specific effects of environmental UV-light conditions on signaling at these shorter wavelengths.We studied wild-caught gravid female 3-spined sticklebacks Gasterosteus aculeatus of 2 photic habitat types(tea-stained and clear-water lakes),possessing great variation in their UV transmission.In 2 treatments,tea-stained and clear-water,preferences for males viewed under UV-present(UV-1-)and UV-absent(UV-)conditions were tested.A preference for males under UV+conditions was found for females from both habitat types,thus stressing the significance of UV signals in stickleback's mate choice decisions.However,females from both habitat types showed the most pronounced preferences for males under UV-h conditions under clear-water test conditions.Moreover,reflectance measurements revealed that the carotenoid-based orange-red breeding coloration in wild-caught males of both habitat types differed significantly in color intensity(higher in clear-water males)and hue(more red shifted in clear-water males)while no significant differences in UV coloration were found.The differential reflection patterns in longer wavelengths suggest that sticklebacks of both habitat types have adapted to the respective water conditions.Adaptations of UV signals in a sexual context to ambient light conditions in both behavior and coloration seem less evident. | Meike Hiermes Stephanie REHER Ingolf P.RICK Theo C.M.Bakker | 2021 | Current Zoology2021，67，3： | 2 |
| 6 | Mate assessment behavior is correlated to learning ability in female threespine sticklebacks显示文摘In many species, males signal quality with elaborate traits, but females often show inter-individual variation in pref ere nee for these traits. Choosi ng a mate requires multiple cog nitive steps;therefore, cog nitive style (how an in dividual processes information) likely in fluences the perception of sexual signals and ability to choose a high-quality mate. An important component of cognitive style is flexibility;cognitively flexible individuals are more perceptive to shifts in cues. We hypothesized that cognitively flexible individuals would acquire more information about potential mates, better discern between two quality-signaling traits, and thus be more discriminatory. Here, we show that mate assessment is correlated to other cognitive traits. Although we did not detect an effect of cogn itive style on mate pref ere nee or discriminatio n, we found that female threespi ne sticklebacks Gasterosteus aculeatus that spent more time assessing potential mates (more responsive) in a dichotomous mate choice task reached both the initial and reversal learning criterion in a spatial learning task with fewer errors. However, these highly responsive females made more consecutive mistakes immediately at the beginning of the reversal phase, suggest!ng that they did not quickly adapt to the en vironmental cha nge but in stead rapidly formed strict routi nes duri ng the learning task that were eventually reversible after repeated errors. Furthermore, we found evidenee for condition-dependent mate pref ere nee, with larger females preferring the high-quality male. These are among the first results that illustrate how cog nitive traits might in flue nee mate choice, which has implicati ons for the st re ngth and di recti on of sexual selection. | Taylor L.RYSTROM Theo C.M.BAKKER Ingolf P.RICK | 2019 | Current Zoology2019，65，3： | 2 |
| 7 | Ribosomally synthesized antimicrobial peptides : their function, structure, biogenesis and mechanism of action 显示文摘 | Jon N M Ingolf F N | 1997 | Arch Microbiol1997，167，： | 1 |
| 8 | Thermal investigations of amber and copal显示文摘 | Michael Feist Ingolf Lamprecht Frank MUller | 2007 | Thermochimica Aeta2007，，458： | 1 |
| 9 | In vivo high-resolution magnetic resonance elastography of the uterine corpus and cervix显示文摘 | Xuyuan Jiang Patrick Asbach Kaspar-Josche Streitberger Anke Thomas Bernd Hamm Jürgen Braun Ingolf Sack Jing Guo | 2014 | European Radiology2014，，： | 1 |
| 10 | Bacteriocins: safe, natural antimicrobials for food preservation 显示文摘 | Jennifer Cleveland Thomas J Montville Ingolf F Nes | 2001 | International Journal of Food Microbiology2001，71，： | 1 |
| 11 | Bacterocins:safe,natural antimicrobials for food preservation显示文摘 | Jennifer C Thomas J M Ingolf F N | 2001 | International Journal of Food Microbiology2001，71，： | 1 |
| 12 | In Vivo Abdominal Magnetic Resonance Elastography for the Assessment of Portal Hypertension Before and After Transjugular Intrahepatic Portosystemic Shunt Implantation显示文摘 | Jing Guo Carsten Büning Eckart Schott Thomas Kr?ncke Jürgen Braun Ingolf Sack Christian Althoff | 2015 | Investigative Radiology2015，，： | 1 |
| 13 | Bacteriocin : Sate, natural antimicrobials for food pres- Exwation显示文摘 | Cleveland J Thomas J M Ingolf F N | 2001 | Inter Food Microbial2001，71，1： | 1 |
| 14 | The antigenic response of β-lactogloblin is modulated by thermally induced aggregation 显示文摘 | Kleber N Ingolf K Sven I | 2004 | Eur Food Res Technol2004，219，： | 1 |
| 15 | Bacteriocins: safe, natural antimicrobials for food preservation显示文摘 | JENNIFER C THOMAS J M INGOLF F N | 2001 | lnternat J Food Micro biol2001，71，1： | 1 |
| 16 | How reliable should auditors:Optimal monitoring in principal-agent relationships显示文摘 | Ingolf Dittmann | 2009 | European Journal Political Economy2009，，5： | 1 |
| 17 | Effects of plant extracts on microbial growth, color change and lipid oxidation in cooked beef 显示文摘 | Juhee A Ingolf U G Azlin M | 2007 | Food Microbiology2007，，24： | 1 |
| 18 | How reliable should auditors:Optimal monitoring in principal-agent relationships 显示文摘 | Ingolf Dittmann | 1999 | European Journal Political Economy1999，，5： | 1 |
| 19 | Bacterioneins: safe, natural antimicrobials for food preservation 显示文摘 | Jennifer Cleveland Thomas J Montville Ingolf Nes | 2001 | International Journal of food Microbiology2001，71，1： | 1 |
| 20 | Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef 显示文摘 | Juhee Ahna Ingolf U Grunb Azlin Mustapha | 2007 | Food Microbiology2007，，24： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员