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| 1 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 2 | Spares provisioning for repairable items: Cyclic queues in light traffic显示文摘 | Gross D Ince J F | 1978 | AIIE Transactions1978，10，： | 2 |
| 3 | Analgesia in preterm newborns: the comparative effects of sucrose and glucose 显示文摘 | Okan F Coban A Ince Z | 2007 | Eur J Pediatr2007，166，10： | 1 |
| 4 | Maximum likelihood classification, optimal or problematic? A comparison with the nearest neighbor classification显示文摘 | Ince F | 1987 | Intl J Remote Sensing1987，12，： | 1 |
| 5 | Direct observation of the human cerebral microcirculation during aneurysm surgery reveals in- creased arteriolar contractility 显示文摘 | PENNINGS F A BOUMA G J INCE C | 2004 | Stroke2004，35，6： | 1 |
| 6 | Microstructure and macroscopic prop- erties of hybrid carbon nanofibers/silica fume cement composites 显示文摘 | Sanchez F Ince C | 2009 | Composites Science and Technology2009，69，78： | 1 |
| 7 | Computer estimation of crowd densityusing digitized aerial photographs显示文摘 | Khan M A Ince F | 1989 | The Arabian Journalfor Science and Engineering1989，14，4： | 1 |
| 8 | Respirometric kinetic parameter calculations of a batch jet loop bioreactor treating leachate and oxygen uptake rate estimation by DTM显示文摘 | Ince M Yildiz F Engin G O | 2008 | Journal of Hazardous Materials2008，153，3： | 1 |
| 9 | Survey Of The OccurrenceOf Aflatoxin M1 In Cheeses Produced By Dairy Ewe'S Milk In Urfa City, Turkey 显示文摘 | Filazi A ince S Temamoaullari F | 2010 | Ankara tiniversitesi Veteriner Fakahesi Dergisi2010，57，3： | 1 |
| 10 | The association between baseline characteristics and the outcome of foot lesions in a UK population with diabetes显示文摘 | Ince P Kendrick D Game F | 2007 | Diabet Med2007，24，9： | 1 |
| 11 | Classification of single trial motor imagery EEG recordings with subject adapted non-dyadic arbitrary time-frequency tilings显示文摘 | Ince N F Arica S Tewfik A | 2006 | J Neural Eng2006，3，3： | 1 |
| 12 | Analgesia in preterm newborns : Thecomparative effects of sucrose and glucose 显示文摘 | Okan F Coban A Ince Zf | 2007 | Eur J Pediatr2007，166，10： | 1 |
| 13 | Persistence of high CD40 and CD40L expression after restorative proctocolectomy for ulcerative colitis显示文摘AIM: To focus on the role of CD40 and CD40L in their pathogenesis.METHODS: We analyzed by immunohistochemistry the CD40 and CD40L expression in the pouch mucosa of 28 patients who had undergone RPC for UC, in the terminal ileum of 6 patients with UC and 11 healthy subjects. We also examined by flow cytometry the expression of CD40 by B lymphocytes and monocytes in the peripheral blood of 20 pouch patients, 15 UC patients and 11 healthy controls.RESULTS: Ileal pouch mucosa leukocytes presented a significantly higher expression of CD40 and CD40L as compared to controls. This alteration correlated with pouchitis, but was also present in the healthy pouch and in the terminal ileum of UC patients. CD40 expression of peripheral B lymphocytes was significantly higher in patients with UC and pouch, respect to controls. Increased CD40 levels in blood B cells of pouch patients correlatedwith the presence of spondyloarthropathy, but not with pouchitis, or inflammatory indices.CONCLUSION: High CD40 expression in the ileal pouch mucosa could be implied in the pathogenesis of pouchitis following proctocolectomy for UC, whereas its increased levels on peripheral blood B lymphocytes are associated with the presence of extraintestinal manifestations. | Lino Polese Imerio Angriman Giuseppe De Franchis Attilio Cecchetto Giacomo C.Sturniolo Renata D'Incà Marco Scarpa Cesare Ruffolo Lorenzo Norberto Mauro Frego Davide F D'Amico | 2005 | World Journal of Gastroenterology2005，11，34： | 1 |
| 14 | Adapting sub-ject specific motor imagery EEG patterns in space-time-fre-quency for a brain computer interface 显示文摘 | INCE N F GOKSU F TEWFIK A H | 2009 | Biomed SignalProcess Control2009，4，3： | 1 |
| 15 | Ameliorative effects of potassium phosphate on salt-stressed pepper and cucumber显示文摘 | Kaya C Higgs D Ince F | 2003 | Journal of Plant Nutrition2003，26，4： | 1 |
| 16 | Effects of wetlanddepth and flow rate on resident time distribution characteris-tics显示文摘 | Jeff Holland Jay F Martin Timothy Inc | 2004 | Ecological Engineering2004，23，3： | 1 |
| 17 | Identification of damaged wheat kernels and cracked- shell hazelnuts with impact acoustics time - frequency patterns 显示文摘 | Ince N F Onaran I Pearson T C | 2008 | Transactions of the ASABE2008，51，4： | 1 |
| 18 | One-step fab- rication of biocompatible carboxymethyl cellulose polymeric particles for drug delivery systems 显示文摘 | BUTUN S INCE F G ERDUGAN H | 2011 | Carbohydr Polym2011，86，2： | 1 |
| 19 | A GIS model for settlement suitability regarding disaster mitigation, a case study in Bolu Turkey显示文摘 | Alparslan E Ince F Erkan B | 2008 | Engineering Geology2008，96，： | 1 |
| 20 | Analgesia in preterm newborns: the comparative effects of sucrose and glucose显示文摘 | Okan F Coban A Ince Z | 2007 | Eur J Pediatr2007，166，10： | 1 |
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