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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Effectiveness of hepatitis B virus vaccination program in Egypt:Multicenter national project显示文摘AIM:To assess the effectiveness of hepatitis B virus(HBV) vaccination program among fully vaccinated children.METHODS:A national community based crosssectional study was carried out in 6 governorates representing Egypt. A total of 3600 children aged from 9 mo to 16 years who were fully vaccinated with HBV vaccine during infancy were recruited. Face to face interviews were carried out and sera were evaluated for hepatitis B surface antigen(HBsA g),anti-HBV core antibodies(total) and quantitative detection of hepatitis B surface antibody using enzyme linked immunoassays techniques. Samples positive to HBs Ag/anti-HBV core antibodies were subjected to quantitative HBV-DNA detection by real time polymerase chain reaction with 3.8 IU/L detection limit. RESULTS:Sero-protection was detected among 2059 children(57.2%) with geometric mean titers 75.4 ± 3.6 IU/L compared to 3.1 ± 2.1 IU/L among nonseroprotected children. Multivariate logistic analysis revealed that older age and female gender were the significant predicting variables for having non seroprotective level,with adjusted odds ratio 3.3,9.1and 14.2 among children aged 5 to < 10,10 to < 15 and ≥ 15 years respectively compared to those < 5 years and 1.1 among girls compared to boys with P < 0.01. HBs Ag was positive in 0.11% and breakthrough infection was 0.36% and 0.39% depending on positivity of anti-HBc and DNA detection respectively. The prevalence of HBV infection was significantly higher among children aged ≥ 7 years(0.59%) compared to 0.07% among younger children with odds ratio equal to 8.4(95%CI:1.1-64.2) and P < 0.01.The prevalence was higher among girls(0.48%) than boys(0.29%) with P > 0.05. C ON C LU S I ON :T he E gy pt ian c ompuls or y H B V vaccination program provides adequate protection. Occult HBV infection exists among apparently healthy vaccinated children. Adherence to infection control measures is mandatory. | Iman I Salama Samia M Sami Zeinab Nabil Ahmed Said Manal H El-Sayed Lobna A El Etreby Thanaa M Rabah Dalia M Elmosalami Amany T Abdel Hamid Somaia I Salama Aida M Abdel Mohsen Hanaa M Emam Safaa M Elserougy Amal I Hassanain Naglaa F Abd Alhalim Fatma A Shaaban Samia A Hemeda Nihad A Ibrahim Ammal M Metwally | 2015 | World Journal of Hepatology2015，7，22： | 2 |
| 3 | Efficacy and safety of treatment of hepatitis C virus infection in renal transplant recipients显示文摘AIM: To assess the efficacy and safety of combinedpegylated interferon and ribavirin therapy in hepatitis C virus (HCV) infection in renal transplant recipients. METHODS: This is a retrospective chart review of post renal transplant patients who were positive for anti-HCV and HCV-RNA, and who have received treatment with combination of pegylated interferon and ribavirin between October 2003 and December 2008. Only patients with stable graft function and absence of evidence of cirrhosis and who received the therapy for continuous 48 wk were included. Nineteen patients (13 male and 6 female) were identified and included. The patient's complete blood count, liver and kidney prof ile, and cal- culated glomerular f iltration rate (GFR) were monitored every 6-8 wk while on treatment. HCV-RNA was tested at 12 wk for early virological response, at 48 wk for end of treatment response (ETR), and then retested at 24, and 48 wk after completion of therapy for sustained virological response (SVR). Liver biopsies were obtained before treatment from all patients and graft kidney biopsies were performed as required. RESULTS: Of the entire cohort, 9 patients (47.4%) showed an ETR and 8 had SVR (42.1%). Of the 8 patients with abnormal alanine aminotransferase (ALT) levels at baseline, 78.9% had their ALT normalized (including the virological non responders). ALT was normal in all responders at the end of therapy and at 24 wk post therapy (100%). Only one patient (5.3%) developed an increase in creatinine and decline in GFR from baseline towards the end of treatment. This patient's kidney biopsy revealed borderline rejection. There was no impact on response by HCV-genotype, initial HCV RNA load, age or sex of the patient or duration post transplant before commencement of therapy. All patients tolerated treatment in the same way as non-transplant with no unusual or increased occurrence of side effects. CONCLUSION: The combination of pegylated interferon and ribavirin is effective in suppressing HCV-RNA,with a low risk of graft rejection or failure in HCV infected renal transplant recipients. | Abdulrahman A Aljumah Mohamed A Saeed Ahmed I Al Flaiw Ibrahim H Al Traif Abduljaleel M Al Alwan Salem H Al Qurashi Ghormallah A Al Ghamdi Fayez F Al Hejaili Mohammed A Al Balwi Abdulla A Al Sayyari | 2012 | World Journal of Gastroenterology2012，18，1： | 2 |
| 4 | Anfioxidant galloylated flavonol glycosides from Callianclra haemat ocephala 显示文摘 | Moharram F A Marzouk M S A Ibrahim M T | 2011 | Natural Product Research2011，，11： | 1 |
| 5 | Molecu- lar differentiation between two varieties of Ros- marinus officinal grown in north east region of I- raq显示文摘 | Ibrahim K M Mahmood T N Barazanchi F M | 2011 | Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Horticulture2011，68，1： | 1 |
| 6 | A multi -criteria approach to contractor selection 显示文摘 | IBRAHIM M M MIKE J R SAMI M F | 2002 | Engi- neering Construction and Architectural Management2002，9，1： | 1 |
| 7 | The development of live load for long span bridges显示文摘 | Nowak A S Lutomirska M Sheikh Ibrahim F I | 2010 | Bridge Structures-Assessment Design&Construction2010，6，1： | 1 |
| 8 | Mitral stenosis after mitral valve repair for non-rheumatic mitral regurgitation显示文摘 | Ibrahim M F David T E | | 0，，： | 1 |
| 9 | Effect of physical modification on dyeing properties of blended wool/polyester fabric显示文摘 | MICHEAL M N IBRAHIM S F | 2004 | Journal of Engineering and Applied Science2004，51，6： | 1 |
| 10 | Interactive effects of nitrogen and water availabilities on gas exchange and whole-plant carbon allocation in poplar显示文摘 | Ibrahim L Proe M F Cameron A D | 1998 | Tree Physiolo- gy1998，18，7： | 1 |
| 11 | Effect of knit structure and finishing treatments on functional and properties of knitted fabrics 显示文摘 | IBRAHIM N A KHALIFA T F EL-HOSSAMY M B | 2010 | Journal of Industrial Textiles2010，40，1： | 1 |
| 12 | Angiotensin- converting enzyme inhibition and angiotensin ATl-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity显示文摘 | IBRAHIM M A ASHOUR O M IBRAHIM Y F | 2009 | Pharmacological Research2009，60，5： | 1 |
| 13 | Heterotopic pregnancy: a growing diagnostic challenge显示文摘 | Ibrahim AG Badawi F Tahlak M | 2009 | BMJ Case Rep2009，，： | 1 |
| 14 | Properties of some high alumina refractories obtained from different alumina sources显示文摘 | Ibrahim N Abdel F M Embabi H K | 1981 | Ceramics International1981，7，2： | 1 |
| 15 | Effect of dietary protein level with some natural biological feed addi- tives supplementation on productive and physiological performance of Japanese quail 显示文摘 | Abdel-Azeem F A Nematallah G M Ibrahim Faten A A | 2005 | Egyptian Poultry Science2005，25，： | 1 |
| 16 | Photodynamie destruction of Haemophilus parainflu- enzae by endogenously produced porphyrins显示文摘 | VAN D M F W IBRAHIM K STERENBORG H J C M | 1997 | Journal of Photochemistry & Photobiology B Biology1997，40，3： | 1 |
| 17 | Effect of different surface treatments on adhesion of In-Ceram Zirconia to enamel and dentin substrates显示文摘 | Saker S Ibrahim F Ozcan M | 2013 | J Adhes Dent2013，15，4： | 1 |
| 18 | Raising the breasthealth awareness amongst women in an Urban Slum area in Al-exandria显示文摘 | Ibrahim F Kharbousha B Hanaa M | 2011 | Breast Care2011，6，： | 1 |
| 19 | The Importance of Entertainment in the Shopping Center Experience:Evidence from Singapore显示文摘 | Ibrahim M F Wee N C | 2002 | Journal of Real Estate Portfolio Management2002，8，3： | 1 |
| 20 | Modified Egyptian talc as internal and surface treatments for papermaking显示文摘 | Ibrahim M M Mobarak F EI-Din E I S | 2009 | Tappi Journal2009，，4： | 1 |
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