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| 1 | Current trends of sugar consumption in developing societies显示文摘 | Amid I.Ismail Jason M.Tanzer Jennifer L.Dingle | 2006 | Community Dentistry and Oral Epidemiology2006，，6： | 1 |
| 2 | Wireless Network Design:Optimization Models and Solution Procedures显示文摘 | D.Allen I.Ismail J.Kennington E.Olinick | | 0，，09： | 1 |
| 3 | The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries显示文摘 | A. I.Ismail W.Sohn M.Tellez A.Amaya A.Sen H.Hasson N. B.Pitts | 2007 | Community Dentistry and Oral Epidemiology2007，，3： | 1 |
| 4 | 大肠癌中肿瘤干细胞标志物CD133,ALDH1和核β-catenin的预后价值(英文)显示文摘Objective: Colon cancer is one of the most common human malignancies. Cancer stem cells(CSCs), despite being only a small subset of cancer cells, have the capability to self-renew and sustain the tumor. They also have the ability to proliferate. Multiple CSCs-associated markers have been identified in colon cancer including CD133, ALDH1 and β-catenin. The aim of the work was to study the prognostic value of CSCs markers(CD133, ALDH1 and β-catenin), as well as their relationship to clinicopathological features of colon cancer. Methods: CD133, ALDH1 and β-catenin proteins expression was assessed immunohistochemically in a series of colon cancers and their prognostic significance was evaluated. Results: CD133 expression showed significant relationship to tumor stage and lymph node metastasis(P-value 0.004 & < 0.001 respectively), and near significant relationship to liver metastasis(P-value 0.092). ALDH1 was significantly associated with tumor grade, stage and nodal metastasis(P-value 0.021, 0.001 and 0.026 respectively), but its relationship to liver metastasis was near significant(P-value 0.068). Nuclear β-catenin was significantly related to tumor grade, stage, nodal and liver metastasis(P-value 0.001, < 0.001, < 0.001 and 0.008 respectively). Overall survival(OS) was associated inversely with CD133, ALDH1 positivity, and directly with nuclear β-catenin positivity(P-value < 0.001, 0.0001 and < 0.001 respectively). Also recurrence free survival(RFS) was associated inversely with CD133, ALDH1 and directly with nuclear β-catenin positivity(P-value 0.0001, 0.001 and < 0.001 respectively). Conclusion: CD133, ALDH1 and β-catenin expressions of tumor cells have significant impact upon malignant progression of colon cancer and thus patient survival and tumor recurrence. Hence they can be used to predict outcome of colon cancer patients. | Eman H.Abdelbary Hayam E.Rashed Eman I.Ismail Mohamed Abdelgawad | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，8： | 0 |
| 5 | Electro-Optical Model of Soiling Effects on Photovoltaic Panels and Performance Implications显示文摘In this paper,a detailed model of a photovoltaic(PV)panel is used to study the accumulation of dust on solar panels.The presence of dust diminishes the incident light intensity penetrating the panel’s cover glass,as it increases the reflection of light by particles.This phenomenon,commonly known as the“soiling effect”,presents a significant challenge to PV systems on a global scale.Two basic models of the equivalent circuits of a solar cell can be found,namely the single-diode model and the two-diode models.The limitation of efficiency data in manufacturers’datasheets has encouraged us to develop an equivalent electrical model that is efficient under dust conditions,integrated with optical transmittance considerations to investigate the soiling effect.The proposed approach is based on the use of experimental current-voltage(I-V)characteristics with simulated data using MATLAB/Simulink.Our research outcomes underscores the feasibility of accurately quantifying the reduction in energy production resulting from soiling by assessing the optical transmittance of accumulated dust on the surface of PV glass. | A.Asbayou G.P.Smestad I.Ismail A.Soussi A.Elfanaoui L.Bouhouch A.Ihlal | 2024 | Energy Engineering2024，121，2： | 0 |
| 6 | Investigation of SARS-CoV-2 Main Protease Potential Inhibitory Activities of Some Natural Antiviral Compounds Via Molecular Docking and Dynamics Approaches显示文摘Coronaviruses caused an outbreak pandemic disease characterized by a severe acute respiratory distress syndrome leading to the infection of more than 200 million patients and the death of more than 4 million individuals.The primary treatment is either supportive or symptomatic.Natural products have an important role in the development of various drugs.Thus,screening of natural compounds with reported antiviral activities can lead to the discovery of potential inhibitory entities against coronaviruses.In the current study,an in-silico molecular docking experiment was conducted on the effects of some of these natural antiviral phytoconstituents,(e.g.,procyanidin B2,theaflavin,quercetin,ellagic acid,caffeoylquinic acid derivatives,berginin,eudesm-1β,6α,11-triol and arbutin),on the crystal structure of SARS-CoV-2 main protease(PDB ID:6w63)using AutoDock-Vina software.Many of the docked compounds revealed good binding affinity,with procyanidin B2(–8.6 Kcal/mol)and theaflavin(–8.5 Kcal/mol)showing a better or similar binding score as the ligand(–8.5 Kcal/mol).Molecular dynamics simulations were carried out at 100 ns and revealed that procyanidin B2 forms a more stable complex with SARS-CoV-2 main protease than theaflavin.Procyanidin B2,theaflavin,and 4,5-dicaffeoylquinic acid were evaluated for toxicity by ProTox-II webserver and were non-toxic according to the predicted LD50 values and safe on different organs and pathways.Additionally,these phytoconstituents showed good ADME properties and acceptable lipophilicity,as evaluated using WLOGP.Amongst the tested compounds,procyanidin B2 showed the highest lipophilic value.It is worth mentioning that these natural inhibitiors of SARS-CoV-2 main protease are components of green and black tea that can be used as a supporting supplement for COVID patients or as potential nuclei for further drug design and development campaigns. | Nada M.Mostafa Muhammad I.Ismail Amr M.El-Araby Dina M.Bahgat Ahmed M.Elissawy Ahmed M.Mostafa Omayma A.Eldahshan Abdel Nasser B.Singab | 2022 | Phyton-International Journal of Experimental Botany2022，91，5： | 0 |
| 7 | 节律化疗作为体力状况较差的晚期卵巢上皮癌患者的姑息治疗(英文)显示文摘Objective:Previous reports have shown that the gene promoter region of retinoic acid receptor β(RARβ) was hypermethylated in cervical carcinoma,implying the inhibition of gene transcription.The aim of this study was to investigate the association of cervical cancer development with the RARβ gene expression at the mRNA and protein level to assess the impact of RARβ as a marker for early detection of the cancer.Methods:We collected 126 cases of formalin fixed and paraffin embedded cervical tissue specimens as well as 37 cases of fresh tissue samples from women with cervicitis,cervical intraepithelial neoplasia(CIN) and cervical squamous cell carcinoma(CSCC).The RARβ mRNA and protein expression was detected by quantitative RT-PCR and immunohistochemistry,respectively.Results:(1) The mRNA expression of RARβ in CIN and cervical cancer was markedly decreased compared to cervicitis with a statistically very significant difference,but no difference was found between CIN and cervical cancer.(2) RARβ protein was normally expressed in the epithelial cells of cervicitis and partially lost in a few cases,but with the development of cervical lesion pathogenesis and cancer,a significant loss of protein expression was detected in CIN(38%) and CSCC(57%) compared to cervicitis(P < 0.01).Conclusion:The downregulation of RARβ transcription or loss of protein expression is an important indicator of cervical cancer and its precursur lesions.The detection of RARβ expression coupled with aberrant methylation of the gene may become a biomarker for the early prognosis or diagnosis of the cancer. | Eman I.Ismail Mohamed A.Elgawad | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，9： | 0 |
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