|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD. | Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele | 2009 | World Journal of Gastroenterology2009，15，10： | 20 |
| 2 | The apparent, of polyphenol oxidase and phloridzin in the production of apple rooting cofactors显示文摘 | Bassuk N L Hunter L D Howard B H | 1981 | J Hort Sci1981，56，4： | 1 |
| 3 | In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody显示文摘 | Mason K Hunter N | 2000 | Clin Cancer Res2000，6，： | 1 |
| 4 | Partial discharge monitoring for power transformers using UHF sensors, part 1 : sensors and signal interpretation显示文摘 | Judd M D Yang L Hunter B B | 2005 | IEEE Electrical Insulation Magazine2005，21，2： | 1 |
| 5 | Effect of fatigue on force sensation显示文摘 | JONES L A HUNTER I W | 1983 | EXP Neurol1983，81，： | 1 |
| 6 | The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital显示文摘 | Maunder R Hunter J Vincent L | 2003 | CMAJ2003，168，10： | 1 |
| 7 | Predicting enzyme function from sequence: A systematic appraisal显示文摘 | Shah I Hunter L | 1997 | Proc Int Conf Intell Syst Mol Biol1997，5，： | 1 |
| 8 | Optimum preventive maintenance policies 显示文摘 | Barlow R Hunter L | 1960 | European Journal of Operational Research1960，8，： | 1 |
| 9 | Nylon-6 Nano- composites from Alkylammonium-modified Clay: The Role of Alkyl Tails on Exfoliation 显示文摘 | FORNES T D HUNTER D L PAUL D R | 2004 | Macromolecules2004，37，5： | 1 |
| 10 | Stress and anxiety:structural plasticity and epigenetic regulation as a consequence of stress显示文摘 | McEWEN B S EILAND L HUNTER R G | 2012 | Neuropharmacology2012，62，1： | 1 |
| 11 | PremenstrualSyndrome 显示文摘 | Dickerson L M Mazyck P J Hunter M H | 2003 | American Family Physician2003，67，8： | 1 |
| 12 | Global association of air pollution and heart failure: a systematic review and meta-analysis显示文摘 | Anoop SV Shah Jeremy P Langrish Harish Nair David A McAllister Amanda L Hunter Ken Donaldson David E Newby Nicholas L Mills | 2013 | The Lancet2013，，： | 1 |
| 13 | Lumbar facet joint osteoarthritis: A review显示文摘 | Kaliehman L Hunter D | 2007 | Semin Arthritis Rheum2007，37，1： | 1 |
| 14 | Consumers′ Need for Uniqueness:Scale Development and Validation显示文摘 | Tian K T Bearden W O Hunter G L | 2001 | Journal of Consumer Research2001，28，1： | 1 |
| 15 | Maximizing therapeutic gain with gemcitabine and fractionated radiation显示文摘 | Mason KA Milas L Hunter NR | 1999 | Int J Radiat Oncol Biol Phys1999，44，5： | 1 |
| 16 | Effect of sodium montmorillonite source on nyton6/clay nanocomposites显示文摘 | Fornes T D Hunter D L Paul D R | 2004 | Polymer2004，45，7： | 1 |
| 17 | Enhancement of tumor radio response in vivo by gemcitabine显示文摘 | Milas L Fujii T Hunter N | 1999 | Cancer Res1999，59，： | 1 |
| 18 | An international survey of HVI显示文摘 | Hunter L | 1995 | Melliand Textilberiehte1995，76，3： | 1 |
| 19 | Preclinical pharmacology,antitumor activity,and development of pharmacodynamic markers for the novel,potent AKT inhibitor CCT128930显示文摘 | YAP T A WALTON M I HUNTER L J | 2011 | Mol Cancer Ther2011，10，2： | 1 |
| 20 | Lumbar facet joint osteoarthritis:areview显示文摘 | Kalichman L Hunter DJ | 2007 | Semin Arthritis Rheum2007，37，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员