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| 1 | Effect of calycosin on left ventricular ejection fraction and angiogenesis in rat models with myocardial infarction显示文摘OBJECTIVE:To evaluated the effect of calycosin on left ventricular ejection fraction and angiogenesis.METHODS:Adult male Sprague-Dawley rats were randomly assigned into calycosin-treated groups(0.5,1,2,and 4 mg/kg qd),a dimethyl sulfoxide(DMSO),or a sham-operated control group.The myocardial ischaemia(Ml) model was intraperitoneally administered calycosin for 28 days.The survival rates and left ventricular ejection fractions(LVEF)were compared between groups.The expression levels of vascular endothelial growth factor(VEGF)and cluster of differentiation 31(CD31) in ischaemic myocardium were also measured and compared.RESULTS:The construction of MI model resulted in a LVEF reduction of 50% compared with the sham-control.After 28 days,the LVEF value was 10% higher when calycosin(4 mg/kg) was administered compared with the DMSO group.The expression of VEGF and CD31 showed a dose-dependent manner when calycosin was administrated.The calycosin-treated(4 mg/kg) group displayed a twofold increase in VEGF expression at both the mRNA and protein levels compared with the DMSO group.In addition,CD31 expression in the microvascular increased 1.5-fold in the 4 mg/kg calycosin-treated group.CONCLUSION:Calycosin improved left ventricular ejection fraction in the MI rat models,induced VEGF expression in the ischaemic myocardium,increased CD31 expression and promoted angiogenesis. | Gao Junqing Chen Tao Jin Huigen Liu Zongjun Zhao Deqiang | 2015 | Journal of Traditional Chinese Medicine2015，35，2： | 6 |
| 2 | Recent progress in Chinese polar upper-atmospheric physics research: review of research advances supported by the Chinese Arctic and Antarctic expeditions显示文摘It has been more than 30 years since the first Chinese Antarctic Expedition took place. Polar upper atmospheric observations started at this time. First began at Great Wall Station and then at Zhongshan Station in Antarctica, and later in the Arctic at Yellow River Station, Kjell Henriksen Observatory on Svalbard, and at the China-Iceland Joint Aurora Observatory in Iceland. In this paper, we reviewed the advances in polar upper atmosphere physics(UAP) based on the Chinese national Arctic and Antarctic research over the last five years. These included newly deployed observatories and research instruments in the Arctic and Antarctic; and new research findings, from ground-based observations, about polar ionosphere dynamics, aurora and particle precipitation, polar plasma convection, geomagnetic pulsations and space plasma waves, space weather in the polar regions, simulations of the polar ionosphere-magnetosphere. In conclusion, suggestions were made for future polar upper atmosphere physics research in China. | HE Fang HU Hongqiao YANG Huigen ZHANG Beichen HUANG Dehong LIU Yonghua HU Zejun LIU Jianjun | 2016 | Advances in Polar Science2016，27，4： | 6 |
| 3 | SuperDARN CUTLASS Finland radar observations of high-latitude magnetic reconnections under northward interplanetary magnetic field (IMF) conditions显示文摘A number of backscatter power enhancement events with 'equatorward-moving radar auroral forms' in the high-latitude ionosphere were observed by SuperDARN CUTLASS Finland radar when the IMF was northward during 09:00 -10:00 UT on 26 March 2004. These events were also associated with sunward flow enhancements at each location in the Northern Hemisphere which were shown in ionospheric convections measured by the SuperDARN radars. These are typical features of high-latitude (lobe) magnetic reconnections. The durations of the velocity enhancements imply that the evolution time of the lobe reconnections is about 8-16 min from their origin at the reconnection site to their addition to the magnetotail lobe again. In additional, the Double Star TC-1 spacecraft was moving from magnetosheath into magnetosphere, and crossing the magnetopause near the subsolar region during this interval, and observed typical low-latitude magnetic reconnection signatures. This infers that the dayside high- and low-latitude reconnections may occur simultaneously. | ZHANG QingHe LIU RuiYuan YANG HuiGen HU HongQiao ZHANG BeiChen DUNLOP Malcolm LESTER Mark BOGDANOVA Yulia WALSH Andrew | 2012 | Science China(Technological Sciences)2012，55，5： | 5 |
| 4 | Statistical characteristics of ionospheric backscatter observed by SuperDARN Zhongshan radar in Antarctica显示文摘Zhongshan HF radar, as one component of SuperDARN, has been established and in operation since April, 2010. Using data from the first two years of its operation, this paper investigates the radar's performance, the diurnal and seasonal variations of ionospheric echoes, and their dependence on geomagnetic activity. Statistical studies show that the occurrence of echoes in different beams varies at different frequencies, which arises from the direction of the beam and the area over which the beam can achieve the orthogonality condition between the wave vector and the Earth's magnetic field. The diurnal variation is obvious with double peak structures both in the occurrence rate and average power at 04-08 UT and 16-17 UT. The line-of-sight velocities are mainly positive on the dayside and negative on the nightside for Beam 0, which is the opposite of the trend for Beam 15. The spectral widths on the dayside are often higher than those on the nightside owing to the high energy particle precipitation in the cusp region. The seasonal variations are more obvious for those beams with larger numbers. The occurrence, the average power, the line-of-sight velocity, and the spectral widths are generally larger in the winter months than in the summer months. The influence of geomagnetic activity on radar echoes is significant. The peak echo occurrence appears on the dayside during geomagnetically quiet times, and shifts toward the nightside and exhibits an obvious decrease with increasing Kp. With increasing geomagnetic activity, the line-of-sight velocities increase, whereas the spectral widths decrease. The frequency dependence is investigated and it is found that in the operating frequency bands in 2010, 9-10 MHz is the most appropriate band for the SuperDARN Zhongshan radar. | HU Hongqiao LIU Erxiao LIU Ruiyuan YANG Huigen ZHANG Beichen | 2013 | Advances in Polar Science2013，24，1： | 4 |
| 5 | Progress in polar upper atmospheric physics research in China显示文摘The Chinese Antarctic Great Wall, Zhongshan, Kunlun and Arctic Yellow River stations have unique geographical locations, well suited to carry out polar upper atmospheric observations. This paper reviews the tremendous history of nearly 30 years of Chinese polar expeditions and major progress in polar upper atmospheric physics research. This includes the polar upper atmospheric physics conjugate observation system at Zhongshan Station in the Antarctic and Yellow River Station in the Arctic, and original research achievements in polar ionospheric fields, aurora and particle precipitation, the polar current system, polar plasma convection, geomagnetic pulsations and space plasma waves, inter-hemispheric comparisons of the space environment, space weather in polar regions, power spectrum of the incoherent scatter radar, ionospheric heating experiments and polar meso- spheric summer echoes, polar ionosphere-magnetosphere numerical simulation and others. Finally, prospects for Chinese polar upper atmospheric physics research are outlined. | LIU Ruiyuan YANG Huigen | 2012 | Advances in Polar Science2012，23，2： | 4 |
| 6 | Enabling the thermal stability of solid electrolyte interphase in Li-ion battery显示文摘Lithium-ion batteries(LIBs)provide power for a variety of applications from the portable electronics to electric vehicles,and now they are supporting the smart grid.Safety of LIBs is of paramount importance in these scenarios.Specifically,thermal safety arouses increasing attention with the piling-up of LIBs.Heat generation can be significant.Hazardous incidents happen when thermal runaway occurs in a single cell level and drives the battery pack failure.Moreover,thermal runaway of LIBs is believed to originate from the exothermic reactions starting from the breakdown of the solid/cathode electrolyte interphase(SEI/CEI).To mitigate this challenge for a safe operation of LIBs,one straightforward and low-cost method is to build thermally stable SEI/CEI.This review gives an overview on the thermal behaviors of SEI/CEI as the first step in thermal runaway.We analyzed the electrolyte composition and the formation process of SEI/CEI that enable SEI/CEI of high thermal stability.It is identified that the stable lithium salts coupled with solvents of high boiling point is one way to enhance thermal stability of the battery system.In addition,the unsaturated bonds,halogen,phosphorus,sulfur,phenol,organic borate,borane,and silane are functional components to facilitate the formation of a thermally stable SEI/CEI,which is the immediate solution to boost thermal stability of high capacity electrodes.Moreover,in-situ polymerization/solidification is effective in enhancing simultaneously the electrochemical,chemical,and thermal stability.Finally,we revealed that only by constructing a stable SEI/CEI simultaneously could we harvest a battery system of high thermal stability. | Chenxi Zu Huigen Yu Hong Li | 2021 | InfoMat2021，3，6： | 3 |
| 7 | Chinese Antarctic Magnetometer Chain at the Cusp Latitude显示文摘A Chinese Antarctic Magnetometer(CAM) chain from Zhongshan Station(ZHS) to Dome-A(DMA) has been established since February 2009.A regular magnetometer is operated at ZHS,and four low power magnetometers are operated along the interior route from ZHS to DMA in the cusp latitude,extending over a distance of 1260 km.These stations fill an important void in the Antarctic magnetometer network.Furthermore,the CAM chain is magnetically conjugated with the Arctic region reaching from the Svalbard archipelago to Daneborg,on the east coast of Greenland.Conjugate measurements using the Arctic and Antarctic magnetometers provide excellent opportunities to investigate phenomena related to the coupling of the solar wind to the magnetosphere and ionosphere,such as magnetic impulse events,flux transfer events,traveling convection vortices and ultra-low frequency waves. | LIU Yonghua HU Hongqiao YANG Huigen ZHANG Beichen SUN Bo WEI Fuhai LIU Yang LIU Jianjun WANG Rui CHEN Zhuotian HU Zejun HAN Desheng SHI Guitao HU Zhengyi WANG Tao AN Chunlei Mike Rose | 2016 | Advances in Polar Science2016，27，2： | 2 |
| 8 | From mandatory icebreaker guiding to a permission regime: changes to the new Russian legislation of the Northern Sea Route显示文摘This article focuses on two issues. The first concerns definitions of the Northern Sea Route(NSR) in old and new Russian legislation, and the second relates to Russian rules on icebreaker guiding. Based on a comprehensive comparative analysis of relevant Russian legal provisions enacted in 2013 and previous laws in this area, we offer the following conclusions.(1) Our legal analysis indicates that Russia's view of the NSR as a historical national transportation route has not changed. However, the new law redefines the scope and coverage of the NSR, which now comprises the internal waters, territorial sea, adjacent zone, and the exclusive economic zone of the Russian Federation. In fact, the new law resolves previous ambiguity regarding extension of the NSR boundary to the high seas.(2) Based on an analysis of the new rules on icebreaker guiding, the article concludes that NSR is transitioning from a mandatory icebreaker guiding regime into a permit regime. This is particularly evident in its provision of a concrete, practical, and predictable clause on permissible or impermissible conditions relating to independent navigation. According to the new rules, it is possible for foreign ships to undertake independent navigation in the NSR. The Russian NSR policy, therefore, appears to have changed significantly, and has future potential for opening the NSR up to the international community. | ZHANG Xia ZOU Leilei TU Jingfang QIAN Zongqi WANG Zeming YANG Huigen | 2014 | Advances in Polar Science2014，25，3： | 2 |
| 9 | Simultaneous optical and radar observations of poleward moving auroral forms under different IMF conditions显示文摘Using high temporal resolution optical data obtained from three-wavelength all-sky imagers at Chinese Yellow River Station in the Arctic, together with the EISCAT Svalbard radar (ESR) and SuperDARN radars, we investigated the dayside poleward moving auroral forms (PMAFs) and the associated plasma features in the polar ionosphere under different interplanetary magnetic field (IMF) conditions, between 0900 and 1010 UT on 22 December 2003. Simultaneous optical and ESR observations revealed that all PMAFs were clearly associated with pulsed particle precipitations. During northward IMF, particles can precipitate into lower altitudes and reach the ionospheric E-region, and there is a reverse convection cell associated with these PMAFs. This cell is one of the typical signatures of the dayside high-latitude (lobe) reconnection in the polar ionosphere. These results indicate that the PMAFs were associated with the high-latitude reconnection. During southward IMF, the PMAFs show larger latitudinal motion, indicating a longer mean lifetime, and the associated ionospheric features indicate that the PMAFs were generated by the dayside low-latitude reconnection. | XING Zanyang YANG Huigen HAN Desheng WU Zhensen LIU Junming HU Zejun ZHANG Qinghe LIU Yonghua ZHANG Beichen HU Hongqiao | 2012 | Advances in Polar Science2012，23，4： | 2 |
| 10 | Dayside poleward moving auroral forms and ionospheric convection under stable interplanetary magnetic field (IMF) conditions显示文摘Using high temporal resolution optical data obtained from three-wavelength all-sky imagers over six winters continuously at Yellow River Station (78.92°N,11.93°E) in Arctic,we statistically investigated the dependence of location of poleward moving auroral forms (PMAFs) on the interplanetary magnetic field (IMF) B z and B y components as a function of MLT and MLAT under stable IMF conditions.It is found that more PMAFs occurred in lower latitude for Bz<0 and there was less evident IMF B y-related prenoon-postnoon asymmetry for Bz<0 than for Bz>0.We found that the PMAFs were distributed over a wide range of MLT when Bz<0,which indicates that the reconnection X-line might spread like an 'S' shape.However,during northward IMF,PMAFs were observed predominantly prenoon for IMF By>0 and postnoon for IMF By<0 associating with the effect of the high-latitude reconnection,which is largely consistent with the theoretical model of the convection flow. | XING ZanYang YANG HuiGen HAN DeSheng WU ZhenSen LIU JunMing HU ZeJun ZHANG QingHe HU HongQiao LIU YongHua | 2013 | Science China(Technological Sciences)2013，56，4： | 2 |
| 11 | Characterization and high-resolution mapping of a late blight resistance locus similar to R 2 in potato 显示文摘 | Park T H Vleeshouwers V Huigen D J | 2005 | Theor Appl Genet2005，111，3： | 1 |
| 12 | Predicting the failure probability of device features in MEMS显示文摘 | Pierce D M Zeyen B Huigens B M | 2011 | IEEE Transactions on Device and Materials Reliability2011，11，3： | 1 |
| 13 | First principles of the MameLuke multi-actor modelling framework for land use change,illustrated with a Philippine case study显示文摘 | HUIGEN M | | 0，，： | 1 |
| 14 | Analysis of the effects of land use change on protected areas in the Philippines显示文摘 | Verburg P H Overmars K P Huigen M G A | 2006 | Applied Geography2006，26，2： | 1 |
| 15 | Segregation analysis and RFLP mapping of R1 and R3 allels conferring racespecific resistance to Phytophthora infestans in progeny of dihaploid potato parents显示文摘 | El-Knarbotly A Leonards-Schipers C Huigen D J | 1994 | Mol Gen Genet1994，，242： | 1 |
| 16 | Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors显示文摘 | Ciechomska M Huigens C A Hugle T | 2013 | Annals of the Rheumatic Diseases2013，72，8： | 1 |
| 17 | Natural interspecific and intraspecifie horizontal transfer of parthenogenesis- inducing Wolbachia in Trichogramma wasps 显示文摘 | Huigens ME de Alnmida RP Boons PA | 2004 | Proc Royal Soc Lond B Biol Sci2004，271，1538： | 1 |
| 18 | Analysis of the effects of land use change on protected areas in the Philippines显示文摘 | Peter H. Verburg Koen P. Overmars Marco G.A. Huigen Wouter T. de Groot A. Veldkamp | 2005 | Applied Geography2005，，2： | 1 |
| 19 | Interplanetary shock-associated aurora显示文摘Interplanetary shocks or solar wind pressure pulses have prompted impacts on Earth's magnetospheric and ionospheric environment, especially in causing dynamic changes to the bright aurora in the polar ionosphere. The auroral phenomenon associated with shock impingements, referred to as shock aurora, exhibits distinct signatures differing from other geophysical features on the dayside polar ionosphere. Shock aurora provides a direct manifestation of the solar wind–magnetosphere–ionosphere interaction. Imagers onboard satellites can obtain the associated large-scale auroral characteristics during shock impingement on the magnetopause. Therefore, auroral data from satellites are very useful for surveying the comprehensive features of shock aurora and their general evolution. Nonetheless, the ground-based high temporal-spatial resolution all-sky imagers installed at scientific stations play an essential role in revealing medium-and small-scale characteristics of shock aurora. Here, we focus on shock aurora imaging signatures measured by imagers onboard satellites and ground-based all-sky imagers. | LIU Jianjun HU Hongqiao HAN Desheng YANG Huigen | 2019 | Advances in Polar Science2019，30，1： | 1 |
| 20 | Lercanidipine hydrochloride versus felodipine sustained-release for mild-to-moderate hypertension: a multi-center, randomized clinical trial显示文摘 | Ying Wu Mengdan Xu Hao Wang Xin Xu Shuiping Zhao Mei Zhang Huigen Jin Jinchuan Yan Bangning Wang Jianbin Gong Xiang Lu Jianqiang Peng Qiuyan Dai | 2014 | Current Medical Research & Opinion2014，，1： | 1 |
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