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| 1 | Modulation of theglycogen synthase kinase-3 family by tyrosine phosphorylation显示文摘 | Hughes K Nikolakaki E Plyte S E ei al | 1993 | EMBO J1993，12，2： | 1 |
| 2 | Supportive care for patients with Guillain-Barr syndrome显示文摘 | Hughes RA Wijdicks EF Benson E et al | 2005 | Arch Neurol2005，62，8： | 1 |
| 3 | Targeter delivery of gas-filled microspheres,contrast agent:four ultrasound imaging显示文摘 | Klibanov AL Hughes MS Devine DV | 1999 | Drug Deliv Rev1999，37，： | 1 |
| 4 | Targeting and ultrasound imaging of microbubble based contrast agents显示文摘 | Klibanov AL Hughes MS Villanueva FS | 1999 | MAGMA1999，8，： | 1 |
| 5 | Evolution of the integrin alpha and beta protein families显示文摘 | Hughes AL | 2001 | J Mol Evol2001，52，1： | 1 |
| 6 | Nanoscale proteinpores modified with PAMAM dendrimers 显示文摘 | Hugh Martin Helen Kinns Nick Mitchell ef al | 2007 | Jacs2007，129，： | 1 |
| 7 | A genome-wide screen identifies a single 13-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins显示文摘 | Xiao Y J Hughes AL Ando J | 2004 | BMC Genomics2004，5，1： | 1 |
| 8 | Theaccyracy of diagnosis of parkinsonian syndromes in specialist movement disorder service显示文摘 | Hughes Al Daniel SE Ben-Shlomo Y | 2002 | Brain2002，125，4： | 1 |
| 9 | The regulation of the ADAMTS4 and ADAiVITS5 aggrecanases in osteoarthritis: a review显示文摘 | Bondeson J Wainwright S Hughes C ct al | 2008 | Clin Exp Rheumatol2008，26，1： | 1 |
| 10 | The 'cleavage' activities of foot-and-moulh disease virus 2A site-directed mulants and naturally occurring '2A-like' sequences显示文摘 | Donnelly M 1 Hughes L E Luke G el al | 2001 | J Gen Virol2001，82，5： | 1 |
| 11 | Laleral Lumbar Inlerbody Fusion显示文摘 | PAWAR A HUGHES A GIRARDI F el al | 2015 | Asian Spine J2015，9，6： | 1 |
| 12 | A genome-wide screen identifies a single beta-defensin gene cluster in the chicken:implications for the origin and evolution of mammalian defensins显示文摘 | Xiao Y Hughes AL Ando J | 2004 | BMC Genomic2004，5，1： | 1 |
| 13 | Genomewide pattern of synonymous nucleotide substitution in two complete genomes of Mycobacterium tuberculosis 显示文摘 | Hughes AL Friedman R Murray M | 2002 | Emerg Infect Dis2002，8，11： | 1 |
| 14 | CD36 expression and lipid metabolism following an oral glucose challenge in South Asians显示文摘AIM:To investigate lipid metabolism and the relationship with monocyte expression of the fatty acid translocase CD36 in South Asians.METHODS:An observational study of South Asians whom as an ethnic group have-a higher risk of developing diabetes.The susceptibility to diabetes is coupled with an earlier and more rapid progression of micro-,and macro-vascular complications.Twentynine healthy South Asian participants [mean age 34.6(8.9) years,76.2% male,mean body-mass index 25.0(5.2) kg/m2] were recruited from an urban residential area of central Birmingham(United Kingdom).The main outcomes measured were post prandial(30 min) and post absorptive(120 min) changes from fasting(0 min) in circulating lipoproteins,lipds and hormones,andmonocyte expression of CD36 post injection of a 75 g oral glucose challenge.The inducements of variations of monocyte CD36 expression were analysed.RESULTS:Our results showed evident changes in monocyte CD36 expression following the glucose challenge(P < 0.001).Non-esterified fatty acids(NEFA) levels decreased progressively during the challenge(P < 0.001),in contrast to increased cholesterol(but not triglyceride) concentrations within very low density lipoprotein(VLDL) and low density lipoprotein subfractions(P < 0.01).Levels of,glucose,serum triglycerides and high density lipoprotein cholesterol remained largely unchanged.Variations of monocyte CD36 were negatively(r =-0.47,P = 0.04) associated to fat from the diet and positively to carbohydrate from the diet(r = 0.65,P < 0.001).CONCLUSION:These data suggest that the initiation of VLDL genesis follows the consumption of glucose within this population,inferring that the sequestration of NEFA from these particles happens due to the increased availability of CD36 receptors.While these are preliminary results,it would appear that lifestyle exposures have a role in moderating the expression of CD36. | Jeetesh V Patel Amitava Banerjee Silvia Montoro-Garcia Eduard Shantsila Mushfique Alam Paul Flinders Kathleen AL Houlton Elizabeth A Hughes Gregory YH Lip Paramjit S Gill | 2015 | World Journal of Diabetes2015，6，7： | 1 |
| 15 | Tumor recurrence in the abdominal wall scar after large-bowel cancer surgery显示文摘 | Hughes ESR McDermott FT Polglase AL | 1983 | Dis Colon Rectum1983，26，： | 1 |
| 16 | Feasibility of brief psychological distress screening by a community-based telephone helpline ~br cancer patients and carers显示文摘 | Hawkes AL Hughes KL Hutchison SD | 2010 | BMC Cancer2010，10，： | 1 |
| 17 | Targeting and ultrasound imaging of microbubble-based contrast agents显示文摘 | Klibanov AL Hughes MS Villanueva FS | 1999 | MAGMA1999，8，3： | 1 |
| 18 | 显示文摘 | Hughes AL | 1999 | Cell Mol Life Sci1999，56，12： | 1 |
| 19 | Reversi-ble ,complete cleavage of si si doul)lebonds l)y isocyanide Insertion 显示文摘 | MAJl'MDAK M HUGH V BKJAN 1 el al | 2013 | Angew Chem IntEd2013，52，12： | 1 |
| 20 | A genome-wide screen identifies a single β-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins显示文摘 | Xiao Y J Hughes AL Ando J | 2004 | BMC Genomics2004，5，1： | 1 |
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