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| 1 | Nat Med:靶向两分子或有助于彻底治愈白血病显示文摘科学家在癌细胞内发现两个信号蛋白能够让癌细胞抵抗化疗。研究表明阻断这两种蛋白能够增强化疗对人类白血病小鼠模型的治疗效果。相关研究结果发表在国际学术期刊NatureMedicine上。研究人员发现在治疗中阻断c-Fos和Dusp1这两个蛋白能够治愈一些受激酶驱动且抵抗治疗的白血病和实体瘤。 | Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes Mohammad Azam Tahir Latif Ming Xu H Leighton Grimes Mohammad Azam | 2017 | 现代生物医学进展2017，17，17： | 4 |
| 2 | Impact of parathyroid hormone on bone marrow-derived stem cell mobilization and migration显示文摘Parathyroid hormone(PTH) is well-known as the principal regulator of calcium homeostasis in the human body and controls bone metabolism via actions on the survival and activation of osteoblasts. The intermittent administration of PTH has been shown to stimulate bone production in mice and men and therefore PTH administration has been recently approved for the treatment of osteoporosis. Besides to its physiological role in bone remodelling PTH has been demonstrated to influence and expand the bone marrow stem cell niche where hematopoietic stem cells, capable of both self-renewal and differentiation, reside. Moreover, intermittent PTH treatment is capable to induce mobilization of progenitor cells from the bone marrow into the bloodstream. This novel function of PTH on modulating the activity of the stem cell niche in the bone marrow as well as on mobilization and regeneration of bone marrow-derived stem cells offers new therapeutic options in bone marrow and stem cell transplantation as well as in the field of ischemic disorders. | Bruno C Huber Ulrich Grabmaier Stefan Brunner | 2014 | World Journal of Stem Cells2014，6，5： | 4 |
| 3 | Biological treatment of ammonium-rich wastewater by partial nitritation and subsequent anaerobic ammonium oxidation ( Anammox ) in a pilot plant 显示文摘 | Fux C Boehler M Huber P | 2002 | Biotechnol2002，99，： | 1 |
| 4 | Epidurdl buttor butorphamol does not reduce side effects from epidural morphine after cesarean birth 显示文摘 | GAMBLING D R HOWELL P HUBER C | 1994 | Anesth Analg1994，78，6： | 1 |
| 5 | Biological treatment of ammonium-rich wastewater by partial nitritation and subsequent anaerobic ammonium oxidation (anammox) in a pilot plant 显示文摘 | Fux C Boehler M Huber P | 2002 | Journal of Biotechnology2002，99，3： | 1 |
| 6 | Sucrose-phosphate synthase and other sucrose metabolizing enzymes in fruit of various species 显示文摘 | Hubbard N L Pharr D M Huber S C | 1991 | Physiol Plant1991，82，： | 1 |
| 7 | Role of sucrose phosphate synthase in sucrose biosynthesis in ripening bananas and its relationship to the respiratory climacteric 显示文摘 | HUBBARD N L PARR D M HUBER S C | 1990 | Plant Physiol1990，94，1： | 1 |
| 8 | Differential response of nitrate reductase and sucrose phosphate synthase activation to inorganic and organic salts,in vitro and in situ显示文摘 | Huber S C Huber J L Kaider W M | 1994 | Plant Physiol1994，，92： | 1 |
| 9 | Hepatic synthersis and clearance of components of the fibrinolytic system in healthy volunteers and in patients with different stages of liver cirrhosis显示文摘 | Huber K Kirchheimer JC Korninger C | 1991 | Thromb Res1991，62，5： | 1 |
| 10 | TGF -β lates the CD^+ CD25^T T cell pool and the expression of Foxp3 invivo 显示文摘 | Schramm C Huber S Protschka M | 2004 | Int Imnmnol2004，16，9： | 1 |
| 11 | TGF-bregulates the CD4+ CD25+ T cells pool and the expression of Foxp3 in vivo 显示文摘 | Sehamm C Huber S Protschka M | 2004 | Int Immunol2004，16，9： | 1 |
| 12 | Preparative two-dimensional gel electrophoresis of membrane proteins显示文摘 | Pasquali C Fialka l Huber LA | 1997 | Electrophoresis1997，18，14： | 1 |
| 13 | PCR detection of the insertion/deletion polymophsim of the human angiotensin--coverting enzyme gene显示文摘 | Rigat B Huber C Corvol P | 1992 | Nucl Acids Res1992，20，： | 1 |
| 14 | Expression of functional CCR and CXCR chemokine receptors in podocytes显示文摘 | Huber T B Reinhardt H C Exner M | 2002 | J Immunol2002，168，12： | 1 |
| 15 | Characterization of diurnal changes in activity of enzymes involved in sucrose biosynthesis显示文摘 | THOMAS W R JRPHILLIP S KERR HUBER S C | 1983 | Plant Physiol1983，73，： | 1 |
| 16 | Role of sucrose phosphate synthase in sucrose biosynthesis in ripening bananas and its relationship to the respiratory climacteric显示文摘 | HUBBARD N L PHARR D M HUBER S C | 1990 | Plant Physiol1990，94，： | 1 |
| 17 | 显示文摘 | Huber G Mitrache C Guglielmetti M | 1998 | Schweiz Med Wochenschr1998，128，48： | 1 |
| 18 | Production of liquid alkanes by aqueousphase processing of biomass- derived carbohydrates 显示文摘 | HUBER G W CHHEDA J N BARREIT C J etal | 2005 | Science2005，，308： | 1 |
| 19 | Prospective study of the spontaneous course of subclinical hypothyroidism:Prognostic value of thyrotropin,thyroid reserve,and thyroid antibodies显示文摘 | Huber G Staub JJ Meier C | 2002 | J Clin Endocrinol Metab2002，87，： | 1 |
| 20 | IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells 显示文摘 | Ali S Huber M Kollewe C | 2007 | Proc Nat Acad Sc U S A2007，104，18： | 1 |
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